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[190378_s_at] Calnexin

Description ZK632.6 /REP_DB=WormBase Gene ID /WP=CE00423 /GEN=cnx-1 /TR=SW:P34652 /GB=CAA80183.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Calnexin
Cluster 6grp_highest_10_10 > 47      6grp_high1_10_10 > 73      4grp_highest_8_8 > 22      4grp_high_8_8 > 07      6grp_highest_nonorm > 66      6grp_total > 74      4grp_total > 01      6grp_cgc > 76      6grp_high1_sub > 03_04      6grp_cgc_sub > 03_04      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2673
1 2 3 4 range
A 1577.6
(-2.2)
P 		1233.5
(-3)
P 		1748.3
(-1.8)
P 		3807.5
(3)
P 		2574
B 1595.1
(-3)
P 		1664.2
(-2.8)
P 		1773.6
(-2.5)
P 		3906.7
(3)
P 		2312
C 1816.1
(-1.8)
P 		1437.3
(-3)
P 		2098.9
(-0.9)
P 		3372.1
(3)
P 		1935
avr 1662.9
(-2.4) 		1445
(-3) 		1873.6
(-1.9) 		3695.4
(3) 		2250

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 699
1 2 3 4 5 6 range
A 1238.5
(-3)
P 		1570.9
(0.6)
P 		1658.9
(1.6)
P 		1790.2
(3)
P 		1422.4
(-1)
P 		1642.3
(1.4)
P 		552
B 1615.4
(-0.7)
P 		1409.7
(-3)
P 		1937.4
(3)
P 		1706.9
(0.4)
P 		1638.5
(-0.4)
P 		1664.8
(-0.1)
P 		528
C 1693.5
(1.3)
P 		1333.4
(-3)
P 		1665.2
(1)
P 		1835.6
(3)
P 		1630
(0.5)
P 		1718.7
(1.6)
P 		502
avr 1515.8
(-1.6) 		1438
(-3) 		1753.8
(2.6) 		1777.6
(3) 		1563.6
(-0.8) 		1675.3
(1.2) 		340
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 565
1 2 3 4 range
A 574.4
(3)
P 		267.8
(-3)
P 		457
(0.7)
P 		557.3
(2.7)
P 		307
B 508.7
(-1.6)
P 		411
(-3)
P 		411
(-3)
P 		832.5
(3)
P 		422
C 601.2
(0.5)
P 		413.2
(-3)
P 		731.5
(3)
P 		568.6
(-0.1)
P 		318
avr 561.4
(1.1) 		364
(-3) 		533.2
(0.5) 		652.8
(3) 		289

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 437
1 2 3 4 5 6 range
A 228.3
(-3)
P 		558.7
(3)
P 		361.3
(-0.6)
P 		454
(1.1)
P 		429.2
(0.6)
P 		399.8
(0.1)
P 		330
B 562.1
(0.1)
P 		469.2
(-2.5)
P 		470.5
(-2.5)
P 		452.1
(-3)
P 		665.7
(3)
P 		620.8
(1.7)
P 		214
C 627.7
(3)
P 		406.9
(-2.1)
P 		423.8
(-1.7)
P 		369.1
(-3)
P 		527.4
(0.7)
P 		575.3
(1.8)
P 		259
avr 472.7
(-0.3) 		478.3
(-0.1) 		418.5
(-3) 		425.1
(-2.7) 		540.8
(3) 		532
(2.6) 		122
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190378_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6097
Sequence Type Exemplar sequence
Representative Public ID ZK632.6 NCBI
Target Description ZK632.6 /REP_DB=WormBase Gene ID /WP=CE00423 /GEN=cnx-1 /TR=SW:P34652 /GB=CAA80183.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Calnexin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066775(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066775 NCBI Caenorhabditis elegans ZK632.6 (Calnexin) mRNA, complete cds. 11/11 None
SNAP00000031476 ENSEMBL cdna:SNAP chromosome:CEL140:III:9814533:9817025:-1 11/11 None
GENEFINDER00000031485 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:9814533:9817025:-1 11/11 None
ZK632.6 ENSEMBL cdna:known chromosome:CEL140:III:9814277:9817031:-1 gene:ZK632.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:9814528-9817021(-) 100.0 100.0
Public Domain and Genome References
Gene Title Calnexin
Gene Symbol cnx-1
Ensembl ZK632.6
Entrez Gene 176390 Entrez gene
SwissProt P34652 EMBL-EBI
WormBase CE00423 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:247494_AT calnexin 1 (CNX1) at
ATGENOME1:17473_AT calnexin 1 (CNX1) at
CANINE:1584805_AT calnexin cfa
CANINE_2:CFA.3766.1.S1_AT calnexin cfa
CANINE_2:CFA.3766.1.S1_S_AT calnexin cfa
CANINE_2:CFA.3766.1.S2_AT calnexin cfa
CANINE_2:CFAAFFX.1477.1.S1_AT calnexin cfa
CANINE_2:CFA.612.1.A1_AT Calnexin cfa
CANINE:1599364_AT Calnexin cfa
DROSOPHILA_2:1627261_S_AT Calnexin 99A dm
DROSGENOME1:152192_AT Calnexin 99A dm
CHICKEN:GGAAFFX.11532.1.S1_S_AT calnexin gga
CHICKEN:GGA.1258.1.S1_AT Similar to calnexin precursor - dog gga
HG-U95AV2:40125_AT calnexin hs
PLASMODIUM_ANOPHELES:200068_S_AT calnexin hs
HG-U133B:200068_S_AT calnexin hs
HG-U133_PLUS_2:200068_S_AT calnexin hs
HG-U133A:200068_S_AT calnexin hs
HG-FOCUS:200068_S_AT calnexin hs
HG-U133A_2:200068_S_AT calnexin hs
U133_X3P:200068_S_AT calnexin hs
HG-U133A:208853_S_AT calnexin hs
HG-U133_PLUS_2:208853_S_AT calnexin hs
HG-U133A_2:208853_S_AT calnexin hs
HG-U133_PLUS_2:208852_S_AT calnexin hs
HG-U133A:208852_S_AT calnexin hs
HG-U133A_2:208852_S_AT calnexin hs
HG-FOCUS:208852_S_AT calnexin hs
HU35KSUBC:RC_R67083_S_AT calnexin hs
HU35KSUBC:RC_N30157_AT calnexin hs
HU35KSUBD:RC_T19271_AT calnexin hs
HUGENEFL:L10284_AT calnexin hs
U133_X3P:G306480_3P_A_AT calnexin hs
U133_X3P:G179831_3P_A_AT calnexin hs
U133_X3P:HS.43679.0.A1_3P_AT calnexin hs
U133_X3P:HS.155560.0.S2_3P_A_AT calnexin hs
HG-U133_PLUS_2:238034_AT calnexin hs
HG-U133B:238034_AT calnexin hs
HG-U95C:53131_AT calnexin hs
HG-U95C:57826_AT calnexin hs
MU11KSUBA:AA163552_G_AT calnexin mm
MU11KSUBA:AA163552_AT calnexin mm
MU11KSUBB:MSA.41901.0_F_AT calnexin mm
MU11KSUBB:MSA.353.0_S_AT calnexin mm
MG-U74AV2:94886_AT calnexin mm
MG-U74AV2:160180_AT calnexin mm
MG-U74CV2:167966_R_AT calnexin mm
MG-U74CV2:169621_I_AT calnexin mm
MOE430A:1415692_S_AT calnexin mm
MOE430B:1415692_S_AT calnexin mm
MOUSE430A_2:1415692_S_AT calnexin mm
MOUSE430_2:1415692_S_AT calnexin mm
MOE430A:1428935_AT calnexin mm
MOUSE430A_2:1428935_AT calnexin mm
MOUSE430_2:1428935_AT calnexin mm
MOE430A:1422845_AT calnexin mm
MOUSE430A_2:1422845_AT calnexin mm
MOUSE430_2:1422845_AT calnexin mm
MU19KSUBA:TC19544_AT Calnexin, mRNA (cDNA clone MGC:7708 IMAGE:3497769) mm
MU19KSUBB:TC34934_AT Calnexin, mRNA (cDNA clone MGC:7708 IMAGE:3497769) mm
MU19KSUBC:TC37046_AT Calnexin, mRNA (cDNA clone MGC:7708 IMAGE:3497769) mm
RN-U34:L18889_AT calnexin rn
RT-U34:L18889_AT calnexin rn
RG-U34A:L18889_AT calnexin rn
RT-U34:RC_AA893328_AT calnexin rn
RG-U34A:RC_AA893328_AT calnexin rn
RAE230A:1388442_AT calnexin rn
RAT230_2:1388442_AT calnexin rn
RAE230A:1371687_AT calnexin rn
RAT230_2:1371687_AT calnexin rn
RAE230A:1371686_AT calnexin rn
RAT230_2:1371686_AT calnexin rn
RT-U34:RC_AI010725_AT Calnexin rn
RG-U34A:RC_AI010725_AT Calnexin rn
RT-U34:RC_AI010725_G_AT Calnexin rn
RG-U34A:RC_AI010725_G_AT Calnexin rn
RG-U34B:RC_AI059038_AT Calnexin rn
RT-U34:RC_AI235707_G_AT Calnexin rn
RG-U34A:RC_AI235707_G_AT Calnexin rn
YEAST_2:1771966_AT Calnexin; integral membrane ER chaperone involved in the folding and quality control of glycoproteins, 24% identical and 31% similar to mammalian calnexin but the Ca+ binding typical of calnexins has not been demonstrated in yeast Sc
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA80183 Hypothetical protein ZK632.6 [Caenorhabditis elegans] ref|NP_499176.1| ZK632.6 [Caenorhabditis elegans] sp|P34652|CALX_CAEEL Calnexin homolog precursor 0.0
blast CAE65122 Hypothetical protein CBG09987 [Caenorhabditis briggsae] 0.0
blast BAB40783.1 calcium-binding protein Calnexin [Halocynthia roretzi] 1.0E-134
Protein Domains
Database ID Description E-Value
Pfam IPR001580 EMBL-EBI Calreticulin/calnexin 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_499176.1 1 480-502
ZK632.6 1 480-502
SNAP00000031476 1 480-502
GENEFINDER00000031485 1 480-502
Sequence
Target Sequence 
>C. ELEGANS:190378_S_AT
ataatatcctcatcacatcatcagaagaagactcgtctgatgtagctaaacaaacatttt
acgttaagcaaaaagaagaatatcgtctcgctgcagccactggaaatggaaatggtttct
tccagcaaattatcgacgcaacaaatgaaaaaccatggttgtgggcagtttatattcttt
gcgttcttcttcctcttgttgctatcggagtattttgcttcggaaaacaatcgaaaccaa
ctccaaactttgcgaaaaagtctgatgcttactcagccgatgatgacagagttccgaact
tggtcgatgatgacgaagaagaaattattggagatgaggaagacgatgtgaatcagcctg
gaccatccggttcccagagcaatccagaaccgcaagacgaggaagaaaatgccgaacaac
aatctgcgaattcctcgcaatccagt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATAATATCCTCATCACATCATCAGA 48 27 1295 Antisense
GAAGACTCGTCTGATGTAGCTAAAC 665 339 1321 Antisense
AAGAAGAATATCGTCTCGCTGCAGC 313 151 1367 Antisense
TCTCGCTGCAGCCACTGGAAATGGA 30 611 1380 Antisense
CAGTTTATATTCTTTGCGTTCTTCT 49 207 1460 Antisense
TTCTTCCTCTTGTTGCTATCGGAGT 614 689 1481 Antisense
GCTATCGGAGTATTTTGCTTCGGAA 500 303 1495 Antisense
AAGTCTGATGCTTACTCAGCCGATG 636 157 1552 Antisense
GATGTGAATCAGCCTGGACCATCCG 416 409 1639 Antisense
TTCCCAGAGCAATCCAGAACCGCAA 507 695 1665 Antisense
ATCTGCGAATTCCTCGCAATCCAGT 315 33 1716 Antisense
Sequence Source Affymetrix Proprietary Database