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[190358_at] sorbitol dehydrogenase

Description R04B5.5 /REP_DB=WormBase Gene ID /WP=CE06215 /TR=Q21702 /GB=CAA94841.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=sorbitol dehydrogenase
Cluster 6grp_highest_10_10 > 35      6grp_high1_10_10 > 53      6grp_highest_nonorm > 72      6grp_total > 20      4grp_total > 63      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 188
1 2 3 4 range
A 136.8
(2.9)
P 		71.5
(-0.6)
A 		137.9
(3)
P 		27.2
(-3)
A 		111
B 143.8
(0.5)
P 		48.4
(-2.8)
M 		215.6
(3)
P 		41.9
(-3)
A 		174
C 190.7
(2.2)
P 		42.8
(-3)
A 		212.4
(3)
P 		52.4
(-2.7)
A 		170
avr 157.1
(1.7) 		54.2
(-2.4) 		188.6
(3) 		40.5
(-3) 		148

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 447
1 2 3 4 5 6 range
A 236.8
(-3)
P 		521.2
(1.8)
P 		593.8
(3)
P 		491.4
(1.3)
P 		238.6
(-3)
P 		300.5
(-1.9)
P 		357
B 165.3
(-3)
P 		514.3
(2.5)
P 		548.8
(3)
P 		354
(-0)
P 		372.3
(0.2)
P 		303.9
(-0.8)
P 		384
C 146.8
(-3)
P 		435.8
(1.1)
P 		572.6
(3)
P 		470.8
(1.6)
P 		207.8
(-2.1)
P 		419.9
(0.8)
P 		426
avr 183
(-3) 		490.4
(1.7) 		571.7
(3) 		438.7
(0.9) 		272.9
(-1.6) 		341.4
(-0.6) 		389
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 70
1 2 3 4 range
A 49.8
(3)
P 		15.5
(-1.5)
A 		36.1
(1.2)
P 		4
(-3)
A 		46
B 45.8
(2.4)
P 		11.9
(-2.6)
M 		50
(3)
P 		8.9
(-3)
A 		41
C 63.1
(2)
P 		12.3
(-2.7)
A 		74
(3)
P 		8.8
(-3)
A 		65
avr 52.9
(2.9) 		13.2
(-2.2) 		53.4
(3) 		7.2
(-3) 		46

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 142
1 2 3 4 5 6 range
A 43.7
(-3)
P 		185.3
(3)
P 		129.3
(0.6)
P 		124.6
(0.4)
P 		72
(-1.8)
P 		73.2
(-1.8)
P 		142
B 57.5
(-3)
P 		171.2
(3)
P 		133.3
(1)
P 		93.8
(-1.1)
P 		151.3
(1.9)
P 		113.3
(-0.1)
P 		114
C 54.4
(-3)
P 		133
(2.2)
P 		145.7
(3)
P 		94.7
(-0.4)
P 		67.3
(-2.2)
P 		140.6
(2.7)
P 		91
avr 51.9
(-3) 		163.2
(3) 		136.1
(1.5) 		104.4
(-0.2) 		96.9
(-0.6) 		109
(0.1) 		111
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190358_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11409
Sequence Type Exemplar sequence
Representative Public ID R04B5.5 NCBI
Target Description R04B5.5 /REP_DB=WormBase Gene ID /WP=CE06215 /TR=Q21702 /GB=CAA94841.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=sorbitol dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073190(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073190 NCBI Caenorhabditis elegans R04B5.5 (R04B5.5) mRNA, complete cds. 11/11 None
SNAP00000020537 ENSEMBL cdna:SNAP chromosome:CEL140:V:10090070:10091499:1 11/11 None
GENEFINDER00000020551 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10090070:10091499:1 11/11 None
R04B5.5 ENSEMBL cdna:known chromosome:CEL140:V:10090070:10091579:1 gene:R04B5.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10090069-10091499(+) 100.0 100.0
Public Domain and Genome References
Gene Title sorbitol dehydrogenase
Ensembl R04B5.5
Entrez Gene 179405 Entrez gene
SwissProt Q21702 EMBL-EBI
WormBase CE06215 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.18326.1.S1_S_AT similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) cfa
CANINE_2:CFAAFFX.21119.1.S1_AT similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) cfa
DROSOPHILA_2:1639892_AT Sorbitol dehydrogenase 1 dm
DROSGENOME1:141450_AT Sorbitol dehydrogenase 1 dm
CHICKEN:GGA.9991.1.S1_AT sorbitol dehydrogenase gga
HG-U133_PLUS_2:201562_S_AT sorbitol dehydrogenase hs
HG-U133A:201562_S_AT sorbitol dehydrogenase hs
HG-U133A_2:201562_S_AT sorbitol dehydrogenase hs
HG-U133_PLUS_2:201563_AT sorbitol dehydrogenase hs
HG-U133A:201563_AT sorbitol dehydrogenase hs
HG-FOCUS:201563_AT sorbitol dehydrogenase hs
HG-U133A_2:201563_AT sorbitol dehydrogenase hs
HUGENEFL:L29008_AT sorbitol dehydrogenase hs
U133_X3P:G496077_3P_AT sorbitol dehydrogenase hs
U133_X3P:G4507154_3P_A_AT sorbitol dehydrogenase hs
HG-U95AV2:38763_AT sorbitol dehydrogenase hs
MOE430A:1426584_A_AT sorbitol dehydrogenase 1 mm
MOUSE430A_2:1426584_A_AT sorbitol dehydrogenase 1 mm
MOUSE430_2:1426584_A_AT sorbitol dehydrogenase 1 mm
MOUSE430_2:1438183_X_AT sorbitol dehydrogenase 1 mm
MOE430A:1438183_X_AT sorbitol dehydrogenase 1 mm
MOUSE430A_2:1438183_X_AT sorbitol dehydrogenase 1 mm
MU11KSUBA:U27014_S_AT sorbitol dehydrogenase 1 mm
MG-U74AV2:162078_AT sorbitol dehydrogenase 1 mm
MG-U74BV2:164338_F_AT sorbitol dehydrogenase 1 mm
MG-U74CV2:171355_AT sorbitol dehydrogenase 1 mm
MG-U74CV2:170584_AT sorbitol dehydrogenase 1 mm
MG-U74CV2:171348_AT Sorbitol dehydrogenase 1 (Sdh1), mRNA mm
MU19KSUBB:TC31726_AT Sorbitol dehydrogenase 1 (Sdh1), mRNA mm
MU19KSUBB:TC31726_G_AT Sorbitol dehydrogenase 1 (Sdh1), mRNA mm
RG-U34A:RC_AI030175_S_AT sorbitol dehydrogenase rn
RG-U34A:X74593_AT sorbitol dehydrogenase rn
RAE230A:1369636_AT sorbitol dehydrogenase rn
RAT230_2:1369636_AT sorbitol dehydrogenase rn
RAE230A:1369635_AT sorbitol dehydrogenase rn
RAT230_2:1369635_AT sorbitol dehydrogenase rn
YEAST_2:1773903_AT Xylitol dehydrogenase, converts xylitol to D-xylulose in the endogenous xylose utilization pathway Sc
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4024 alcohol dehydrogenase activity, zinc-dependent inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94841 Hypothetical protein R04B5.5 [Caenorhabditis elegans] ref|NP_505591.1| R04B5.5 [Caenorhabditis elegans] 0.0
blast CAE64010 Hypothetical protein CBG08605 [Caenorhabditis briggsae] 0.0
blast CAE64012 Hypothetical protein CBG08607 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002085 EMBL-EBI Zinc-containing alcohol dehydrogenase superfamily 5.1E-103
Sequence
Target Sequence 
>C. ELEGANS:190358_AT
agacggggctcttattgaaccactttccgttgcgattcatgcgtgtcgacgtggaaatgt
tcaaatgggacaccgagttcttgttctcggagccggtcctattggagttttaaacctcat
taccgctaaagctgtaggagctggaaaagtagttattactgatttagatgatggcagact
tgcgctcgcaaagaaacttggggcagatgcaacaattaacgttaaaggaaagtcattgga
cgcagttaaatcggagatcattaccgcactgggtgatcagcagccggatgtctgtattga
gtgtactggcgcacagccgagtatcgagacagctataacgaccaccaaatcaggtggagt
catagttcttgtcggattgggagcagaccgagttgaaataccaataattgaatcagcaac
tagagaagttgacatgcgtgggattttcagatatgtaaactgctacccaacagcaatcga
actcatttcatctggaaaactaaatttgtcggggctaacacgtgctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGACGGGGCTCTTATTGAACCACTT 194 71 450 Antisense
ACTTTCCGTTGCGATTCATGCGTGT 674 101 471 Antisense
AATGGGACACCGAGTTCTTGTTCTC 245 163 513 Antisense
CTCGGAGCCGGTCCTATTGGAGTTT 170 233 535 Antisense
TAAACCTCATTACCGCTAAAGCTGT 335 637 560 Antisense
TAGATGATGGCAGACTTGCGCTCGC 577 651 614 Antisense
GGAGATCATTACCGCACTGGGTGAT 478 517 702 Antisense
GGTGATCAGCAGCCGGATGTCTGTA 270 501 721 Antisense
TTGAGTGTACTGGCGCACAGCCGAG 19 705 746 Antisense
GGTGGAGTCATAGTTCTTGTCGGAT 317 499 802 Antisense
AATTTGTCGGGGCTAACACGTGCTC 185 175 952 Antisense
Sequence Source Affymetrix Proprietary Database