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[190330_s_at] acyl-CoA thioesterase

Description F25E2.3 /REP_DB=WormBase Gene ID /WP=CE07132 /TR=Q19781 /GB=AAA91256.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=acyl-CoA thioesterase
Cluster 6grp_highest_10_10 > 72      6grp_high1_10_10 > 27      6grp_highest_nonorm > 60      6grp_total > 27      4grp_total > 54      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 857
1 2 3 4 range
A 924.7
(3)
P 		430
(-0.6)
P 		320.3
(-1.3)
P 		89.1
(-3)
M 		836
B 848.8
(3)
P 		388.1
(-0.5)
P 		357.3
(-0.8)
P 		67.7
(-3)
A 		781
C 910.8
(3)
P 		400.9
(-0.7)
P 		330.1
(-1.2)
P 		82.2
(-3)
A 		829
avr 894.8
(3) 		406.3
(-0.6) 		335.9
(-1.1) 		79.7
(-3) 		815

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 518
1 2 3 4 5 6 range
A 619.4
(3)
P 		444.4
(0.4)
P 		290.5
(-1.9)
P 		250.4
(-2.5)
P 		214
(-3)
P 		394.7
(-0.3)
P 		405
B 678.4
(3)
P 		392.5
(-0.9)
P 		320.7
(-1.9)
P 		239.9
(-3)
P 		256.6
(-2.8)
P 		365.4
(-1.3)
P 		439
C 728.1
(3)
P 		376.4
(-1.1)
P 		346.2
(-1.4)
P 		210.4
(-3)
P 		242.7
(-2.6)
P 		364.2
(-1.2)
P 		518
avr 675.3
(3) 		404.4
(-0.7) 		319.1
(-1.8) 		233.6
(-3) 		237.8
(-2.9) 		374.8
(-1.1) 		442
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 324
1 2 3 4 range
A 336.7
(3)
P 		93.3
(-1.5)
P 		83.7
(-1.7)
P 		13
(-3)
M 		324
B 270.7
(3)
P 		95.9
(-1.1)
P 		82.8
(-1.4)
P 		14.4
(-3)
A 		256
C 301.5
(3)
P 		115.3
(-0.9)
P 		115
(-0.9)
P 		13.9
(-3)
A 		288
avr 303
(3) 		101.5
(-1.2) 		93.8
(-1.3) 		13.8
(-3) 		289

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 228
1 2 3 4 5 6 range
A 114.2
(0.2)
P 		158.1
(3)
P 		63.3
(-3)
P 		63.5
(-3)
P 		64.6
(-2.9)
P 		96.1
(-0.9)
P 		95
B 236.1
(3)
P 		130.7
(-0.7)
P 		77.9
(-2.5)
P 		63.5
(-3)
P 		104.3
(-1.6)
P 		136.3
(-0.5)
P 		173
C 269.9
(3)
P 		114.9
(-1.1)
P 		88.1
(-1.8)
P 		42.3
(-3)
P 		78.5
(-2)
P 		121.9
(-0.9)
P 		228
avr 206.7
(3) 		134.6
(0.1) 		76.4
(-2.2) 		56.4
(-3) 		82.5
(-2) 		118.1
(-0.5) 		150
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190330_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18094
Sequence Type Exemplar sequence
Representative Public ID F25E2.3 NCBI
Target Description F25E2.3 /REP_DB=WormBase Gene ID /WP=CE07132 /TR=Q19781 /GB=AAA91256.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=acyl-CoA thioesterase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075758(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075758 NCBI Caenorhabditis elegans F25E2.3 (F25E2.3) mRNA, complete cds. 11/11 None
SNAP00000017576 ENSEMBL cdna:SNAP chromosome:CEL140:X:811252:813099:-1 11/11 None
GENEFINDER00000017587 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:811252:813099:-1 11/11 None
F25E2.3 ENSEMBL cdna:known chromosome:CEL140:X:811184:813099:-1 gene:F25E2.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:811251-813099(-) 100.0 100.0
Public Domain and Genome References
Gene Title acyl-CoA thioesterase
Ensembl F25E2.3
Entrez Gene 180429 Entrez gene
SwissProt Q19781 EMBL-EBI
WormBase CE35508 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:261560_AT acyl-CoA thioesterase family protein at
CANINE:1584820_AT similar to peroxisomal acyl-CoA thioesterase isoform c cfa
CANINE_2:CFA.10633.1.A1_AT similar to peroxisomal acyl-CoA thioesterase isoform c cfa
CANINE_2:CFA.10633.1.A1_S_AT similar to peroxisomal acyl-CoA thioesterase isoform c cfa
CANINE_2:CFA.19852.1.S1_S_AT similar to peroxisomal acyl-CoA thioesterase isoform c cfa
CHICKEN:GGA.4688.1.S1_AT acyl-CoA thioesterase 8 gga
CHICKEN:GGAAFFX.22071.1.S1_AT acyl-CoA thioesterase 8 gga
HG-U95AV2:36841_AT acyl-CoA thioesterase 8 hs
HG-U133_PLUS_2:204212_AT acyl-CoA thioesterase 8 hs
HG-U133A:204212_AT acyl-CoA thioesterase 8 hs
HG-FOCUS:204212_AT acyl-CoA thioesterase 8 hs
HG-U133A_2:204212_AT acyl-CoA thioesterase 8 hs
HU35KSUBA:X86032_AT acyl-CoA thioesterase 8 hs
HU35KSUBD:RC_H29206_AT acyl-CoA thioesterase 8 hs
U133_X3P:G4885564_3P_AT acyl-CoA thioesterase 8 hs
HG-U95B:47789_AT acyl-CoA thioesterase 8 hs
HG-U133_PLUS_2:236514_AT Acyl-CoA thioesterase 8 hs
HG-U133B:236514_AT Acyl-CoA thioesterase 8 hs
HG-U133_PLUS_2:244484_AT Acyl-CoA thioesterase 8 hs
HG-U133B:244484_AT Acyl-CoA thioesterase 8 hs
HG-U95D:91755_AT Acyl-CoA thioesterase 8 hs
HU35KSUBB:RC_H18458_AT Acyl-CoA thioesterase 8 hs
HU35KSUBC:RC_AA425058_AT Acyl-CoA thioesterase 8 hs
U133_X3P:HS.107040.0.A1_3P_AT Acyl-CoA thioesterase 8 hs
U133_X3P:HS.6511.0.A1_3P_AT Acyl-CoA thioesterase 8 hs
MG-U74AV2:103386_AT acyl-CoA thioesterase 8 mm
MG-U74CV2:166997_AT acyl-CoA thioesterase 8 mm
MOE430A:1417449_AT acyl-CoA thioesterase 8 mm
MOUSE430A_2:1417449_AT acyl-CoA thioesterase 8 mm
MOUSE430_2:1417449_AT acyl-CoA thioesterase 8 mm
MG-U74BV2:116495_AT Acyl-CoA thioesterase 8 (Acot8), mRNA mm
MU19KSUBC:TC38795_AT Acyl-CoA thioesterase 8 (Acot8), mRNA mm
MU19KSUBC:TC39723_AT Acyl-CoA thioesterase 8 (Acot8), mRNA mm
RG-U34C:RC_AI072375_AT peroxisomal acyl-CoA thioesterase 1 rn
RAE230A:1368206_AT peroxisomal acyl-CoA thioesterase 1 rn
RAT230_2:1368206_AT peroxisomal acyl-CoA thioesterase 1 rn
RAE230B:1394902_AT Peroxisomal acyl-CoA thioesterase 1 rn
RAT230_2:1394902_AT Peroxisomal acyl-CoA thioesterase 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6637 acyl-CoA metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16291 acyl-CoA thioesterase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA91256 Hypothetical protein F25E2.3 [Caenorhabditis elegans] ref|NP_508159.2| F25E2.3 [Caenorhabditis elegans] 0.0
blast CAE63617 Hypothetical protein CBG08110 [Caenorhabditis briggsae] emb|CAE56356.1| Hypothetical protein CBG24030 [Caenorhabditis briggsae] 0.0
blast AAA91256 Hypothetical protein F25E2.3 [Caenorhabditis elegans] ref|NP_508159.2| F25E2.3 [Caenorhabditis elegans] 1.0E-146
blast CAE63617 Hypothetical protein CBG08110 [Caenorhabditis briggsae] emb|CAE56356.1| Hypothetical protein CBG24030 [Caenorhabditis briggsae] 1.0E-139
blast AAK68237 Hypothetical protein C37H5.13a [Caenorhabditis elegans] ref|NP_504301.1| C37H5.13a [Caenorhabditis elegans] 1.0E-102
Protein Domains
Database ID Description E-Value
Pfam IPR003703 EMBL-EBI Acyl-CoA thioesterase 1.9E-23
Pfam IPR003703 EMBL-EBI Acyl-CoA thioesterase 4.8E-18
Pfam IPR003703 EMBL-EBI Acyl-CoA thioesterase 2.3E-18
Pfam IPR003703 EMBL-EBI Acyl-CoA thioesterase 4.8E-18
Sequence
Target Sequence 
>C. ELEGANS:190330_S_AT
atgccggaagtaacacctccagaacaattgcttccagctcgagaagcagcgctggaagtg
ctccgcacgaaagaagtcgatgaagtcaccgctggtgtcatccaacattttttgaaagaa
attccagatgcttttgagcgagtttttgatgttcgcccggtcaacccagccaagtacttg
cttaaagaagatactgagccaatgtcgatgatttggattcgagcaagagagaatttggga
gatgatcaccgtctccatcagtgcgtcgctgcttacctcaccgacttgagcatgctcacc
acggcagtacgacctcatatcagaaacggattcatcccttcaatgtctttttccctggat
cattgtatttggatgcatgaaaatgagtttcgaatcgatgattggatgctgtatgagaca
attagctcaaaagctggtggaagtcgtgcatttattgaaggccgtttatggtctcgtgat
ggtcgacttatcatttcgactgctcaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGCCGGAAGTAACACCTCCAGAAC 117 41 508 Antisense
GAGAAGCAGCGCTGGAAGTGCTCCG 682 391 548 Antisense
GAAGTCGATGAAGTCACCGCTGGTG 540 335 580 Antisense
ACCGCTGGTGTCATCCAACATTTTT 463 89 595 Antisense
GCGAGTTTTTGATGTTCGCCCGGTC 165 289 645 Antisense
GTCAACCCAGCCAAGTACTTGCTTA 354 463 667 Antisense
GATACTGAGCCAATGTCGATGATTT 612 423 697 Antisense
GGAGATGATCACCGTCTCCATCAGT 355 519 745 Antisense
GATTCATCCCTTCAATGTCTTTTTC 3 431 836 Antisense
GAAGGCCGTTTATGGTCTCGTGATG 332 333 964 Antisense
TCGACTTATCATTTCGACTGCTCAA 623 601 990 Antisense
Sequence Source Affymetrix Proprietary Database