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[190298_s_at] alcohol dehydrogenase

Description R05D8.8 /REP_DB=WormBase Gene ID /WP=CE23899 /TR=Q9N5G3 /GB=AAF39953.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=alcohol dehydrogenase
Cluster 6grp_highest_10_10 > 58      6grp_high1_10_10 > 84      4grp_highest_8_8 > 43      4grp_high_8_8 > 24      6grp_highest_nonorm > 96      6grp_total > 75      4grp_total > 55      6grp_cgc > 67      6grp_cgc_sub > In      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 257
1 2 3 4 range
A 359.1
(3)
P 		184.2
(-3)
P 		285.7
(0.5)
P 		243.5
(-1)
P 		175
B 406.6
(3)
P 		209.9
(-3)
P 		245.4
(-1.9)
P 		242
(-2)
P 		197
C 440.9
(3)
P 		192.5
(-3)
P 		249.9
(-1.6)
P 		293.3
(-0.6)
P 		248
avr 402.2
(3) 		195.5
(-3) 		260.3
(-1.1) 		259.6
(-1.1) 		207

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1129
1 2 3 4 5 6 range
A 532.3
(-2.2)
P 		433.2
(-3)
P 		1155.3
(3)
P 		896.9
(0.9)
P 		1022.7
(1.9)
P 		965.8
(1.4)
P 		722
B 605.6
(-2.4)
P 		492.2
(-3)
P 		981.1
(-0.3)
P 		960.3
(-0.4)
P 		894.9
(-0.7)
P 		1562.3
(3)
P 		1070
C 465.3
(-3)
P 		542.7
(-2.6)
P 		861.5
(-0.8)
P 		1052.4
(0.3)
P 		750.9
(-1.4)
P 		1532.5
(3)
P 		1067
avr 534.4
(-2.7) 		489.4
(-3) 		999.3
(0.5) 		969.9
(0.3) 		889.5
(-0.2) 		1353.5
(3) 		864
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 110
1 2 3 4 range
A 130.8
(3)
P 		40
(-2.7)
P 		74.7
(-0.5)
P 		35.6
(-3)
P 		95
B 129.7
(3)
P 		51.8
(-3)
P 		56.9
(-2.6)
P 		51.6
(-3)
P 		78
C 146
(3)
P 		55.4
(-2.6)
P 		87.1
(-0.7)
P 		49.5
(-3)
P 		97
avr 135.5
(3) 		49.1
(-2.8) 		72.9
(-1.2) 		45.6
(-3) 		90

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 485
1 2 3 4 5 6 range
A 98.1
(-3)
P 		154.1
(-1.4)
P 		251.6
(1.4)
P 		227.5
(0.7)
P 		308.6
(3)
P 		235.1
(0.9)
P 		211
B 210.7
(-2.3)
P 		163.8
(-3)
P 		238.3
(-1.9)
P 		254.3
(-1.7)
P 		363.6
(-0.1)
P 		582.6
(3)
P 		419
C 172.5
(-2.9)
P 		165.6
(-3)
P 		219.3
(-2.1)
P 		211.6
(-2.2)
P 		243
(-1.7)
P 		513
(3)
P 		347
avr 160.4
(-3) 		161.2
(-3) 		236.4
(-1.4) 		231.1
(-1.5) 		305.1
(0.1) 		443.6
(3) 		283
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190298_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15544
Sequence Type Exemplar sequence
Representative Public ID R05D8.8 NCBI
Target Description R05D8.8 /REP_DB=WormBase Gene ID /WP=CE23899 /TR=Q9N5G3 /GB=AAF39953.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=alcohol dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071351(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071351 NCBI Caenorhabditis elegans DeHydrogenases, Short chain family member (dhs-14) (dhs-14) mRNA, complete cds. 11/11 None
SNAP00000009122 ENSEMBL cdna:SNAP chromosome:CEL140:V:2763846:2766035:-1 11/11 None
GENEFINDER00000009144 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:2763846:2767330:-1 11/11 None
R05D8.8 ENSEMBL cdna:known chromosome:CEL140:V:2763831:2765039:-1 gene:R05D8.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:2763845-2765021(-) 100.0 100.0
Public Domain and Genome References
Gene Title alcohol dehydrogenase
Gene Symbol dhs-14
Ensembl R05D8.8
Entrez Gene 178738 Entrez gene
SwissProt Q9N5G3 EMBL-EBI
WormBase CE23899 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:252070_AT short-chain dehydrogenase/reductase (SDR) family protein at
CANINE:1586142_S_AT similar to dehydrogenase/reductase (SDR family) member 10 cfa
CANINE_2:CFA.10427.1.A1_AT similar to dehydrogenase/reductase (SDR family) member 10 cfa
CANINE_2:CFAAFFX.6781.1.S1_S_AT similar to dehydrogenase/reductase (SDR family) member 10 cfa
HG-U133_PLUS_2:224494_X_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U133B:224494_X_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U133B:224497_X_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U133_PLUS_2:224497_X_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U133_PLUS_2:228713_S_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U133B:228713_S_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U133_PLUS_2:219113_X_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U133A:219113_X_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-FOCUS:219113_X_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U133A_2:219113_X_AT dehydrogenase/reductase (SDR family) member 10 hs
HU35KSUBB:RC_R00296_AT dehydrogenase/reductase (SDR family) member 10 hs
U133_X3P:G13623365_3P_S_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U95B:43419_S_AT dehydrogenase/reductase (SDR family) member 10 hs
HG-U95C:65515_AT dehydrogenase/reductase (SDR family) member 10 hs
MOE430B:1429802_AT dehydrogenase/reductase (SDR family) member 10 mm
MOUSE430_2:1429802_AT dehydrogenase/reductase (SDR family) member 10 mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK18930 Hypothetical protein F12E12.7 [Caenorhabditis elegans] ref|NP_494640.1| F12E12.7 [Caenorhabditis elegans] 1.0E-144
blast NP_503752 DeHydrogenases, Short chain family member (dhs-14) [Caenorhabditis elegans] gb|AAF39953.1| Dehydrogenases, short chain protein 14 [Caenorhabditis elegans] 1.0E-143
blast NP_503752 DeHydrogenases, Short chain family member (dhs-14) [Caenorhabditis elegans] gb|AAF39953.1| Dehydrogenases, short chain protein 14 [Caenorhabditis elegans] 1.0E-136
blast CAE62263 Hypothetical protein CBG06322 [Caenorhabditis briggsae] 1.0E-135
blast CAE66774 Hypothetical protein CBG12129 [Caenorhabditis briggsae] 1.0E-124
blast CAE66773 Hypothetical protein CBG12128 [Caenorhabditis briggsae] 1.0E-119
Protein Domains
Database ID Description E-Value
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 1.0E-60
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 3.0E-54
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 7.9E-51
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 1.0E-60
Sequence
Target Sequence 
>C. ELEGANS:190298_S_AT
gccggagcggcttttaatgacgatcaaggacgtgttggagttgatcaagatgtctcagtt
tacgatagaattatgcaaattaacatgagaagtgtggttactttgactcaaaaagccaag
gagcatttggttaaggctaagggagaagttgtaaatgtttcgagcatcggagcaggacca
caggctcaaccaactttcatgtattatgcaatgtcaaaagccgcattggatcaatatacc
agaagtgctgccatcgatcttattcagtacggggttagagtcaactcggtgagccctgga
gctgtagtgacaggtttcggagaagcaatgggaatgcctgctgatatgcatgagaagtat
ggacatttcatggaatctcgcaaagaatgtattccttgcggaaaaatggggcaacccatc
gacattgccaatataattgcgttcttggctgatcgaaaactctcttcatacattattgga
cagtcgattgtggcagatggaggttcgactttggta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCCGGAGCGGCTTTTAATGACGATC 660 281 292 Antisense
TTCGAGCATCGGAGCAGGACCACAG 345 693 450 Antisense
TACCAGAAGTGCTGCCATCGATCTT 22 651 528 Antisense
CAGTACGGGGTTAGAGTCAACTCGG 430 59 556 Antisense
AGCCCTGGAGCTGTAGTGACAGGTT 3 83 583 Antisense
GCAATGGGAATGCCTGCTGATATGC 364 319 616 Antisense
GGACATTTCATGGAATCTCGCAAAG 210 525 652 Antisense
TGGGGCAACCCATCGACATTGCCAA 620 553 698 Antisense
GGCTGATCGAAAACTCTCTTCATAC 628 539 738 Antisense
AACTCTCTTCATACATTATTGGACA 364 141 749 Antisense
GGCAGATGGAGGTTCGACTTTGGTA 660 531 783 Antisense
Sequence Source Affymetrix Proprietary Database