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[190294_at] Protein phosphatase 2C

Description F33A8.6 /REP_DB=WormBase Gene ID /WP=CE18659 /TR=O62212 /GB=CAB04260.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=Protein phosphatase 2C
Cluster 6grp_highest_10_10 > 03      6grp_high1_10_10 > 11      4grp_highest_8_8 > 24      4grp_high_8_8 > 51      6grp_highest_nonorm > 80      6grp_total > 13      4grp_total > 52      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 278
1 2 3 4 range
A 326.2
(1.6)
P 		393.2
(3)
P 		312.5
(1.3)
P 		114.8
(-3)
P 		278
B 343.5
(2.7)
P 		352.6
(3)
P 		295.4
(1.3)
P 		155.9
(-3)
P 		197
C 317.3
(1.5)
P 		364.6
(3)
P 		303.4
(1.1)
P 		173.3
(-3)
P 		191
avr 329
(1.9) 		370.1
(3) 		303.8
(1.2) 		148
(-3) 		222

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 189
1 2 3 4 5 6 range
A 318
(3)
P 		237.2
(0.3)
P 		287.9
(2)
P 		257.2
(0.9)
P 		197.1
(-1.1)
P 		141
(-3)
P 		177
B 298.6
(2.1)
P 		325.6
(3)
P 		282
(1.5)
P 		305.8
(2.3)
P 		266.6
(1)
P 		145.4
(-3)
P 		180
C 226.2
(1.5)
P 		255.4
(3)
P 		216.9
(1.1)
P 		207.5
(0.6)
P 		194.7
(-0.1)
P 		136.7
(-3)
P 		119
avr 280.9
(3) 		272.7
(2.6) 		262.3
(2.2) 		256.8
(2) 		219.5
(0.4) 		141
(-3) 		140
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 102
1 2 3 4 range
A 118.8
(3)
P 		85.3
(1)
P 		81.7
(0.8)
P 		16.8
(-3)
P 		102
B 109.5
(3)
P 		87.1
(1.2)
P 		68.5
(-0.2)
P 		33.2
(-3)
P 		76
C 105
(2.9)
P 		104.8
(2.9)
P 		105.8
(3)
P 		29.2
(-3)
P 		77
avr 111.1
(3) 		92.4
(1.7) 		85.3
(1.2) 		26.4
(-3) 		85

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 74
1 2 3 4 5 6 range
A 58.6
(-0.1)
P 		84.4
(3)
P 		62.7
(0.4)
P 		65.2
(0.7)
P 		59.5
(0)
P 		34.3
(-3)
P 		50
B 103.9
(2.5)
P 		108.4
(3)
P 		68.5
(-1.4)
P 		81
(-0)
P 		108.3
(3)
P 		54.2
(-3)
P 		54
C 83.8
(3)
P 		77.9
(2.2)
P 		55.2
(-1.1)
P 		41.7
(-3)
P 		63
(0)
P 		45.8
(-2.4)
P 		42
avr 82.1
(1.9) 		90.2
(3) 		62.1
(-0.7) 		62.6
(-0.6) 		76.9
(1.2) 		44.8
(-3) 		45
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190294_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2650
Sequence Type Exemplar sequence
Representative Public ID F33A8.6 NCBI
Target Description F33A8.6 /REP_DB=WormBase Gene ID /WP=CE18659 /TR=O62212 /GB=CAB04260.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=Protein phosphatase 2C
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063969(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063969 NCBI Caenorhabditis elegans F33A8.6 (F33A8.6) mRNA, complete cds. 11/11 None
F33A8.6 ENSEMBL cdna:known chromosome:CEL140:II:11050173:11052240:1 gene:F33A8.6 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000042088 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:11050169-11052237(+) 100.0 100.0
Public Domain and Genome References
Gene Title Protein phosphatase 2C
Ensembl F33A8.6
Entrez Gene 185220 Entrez gene
SwissProt O62212 EMBL-EBI
WormBase CE18659 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:255910_AT protein phosphatase 2C, putative / PP2C, putative at
CANINE_2:CFAAFFX.19259.1.S1_AT similar to integrin-linked kinase-associated protein phosphatase 2C isoform 2 cfa
CHICKEN:GGA.12903.1.S1_AT similar to integrin-linked kinase-associated protein phosphatase 2C isoform 1; protein phosphatase 2c, delta isozyme gga
HG-U133_PLUS_2:221548_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HG-U133A:221548_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HG-U133A_2:221548_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HU35KSUBC:RC_F02863_AT integrin-linked kinase-associated serine/threonine phosphatase 2C hs
U133_X3P:G13432041_3P_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HG-U95C:51005_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HG-U95B:52587_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HG-U95C:63005_I_AT integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HG-U133_PLUS_2:239692_AT Integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HG-U133B:239692_AT Integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HG-U95E:74516_AT Integrin-linked kinase-associated serine/threonine phosphatase 2C hs
HG-U95D:88150_R_AT Integrin-linked kinase-associated serine/threonine phosphatase 2C hs
U133_X3P:HS.129885.0.A1_3P_AT Integrin-linked kinase-associated serine/threonine phosphatase 2C hs
MOUSE430_2:1452506_A_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MOUSE430A_2:1452506_A_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MOE430A:1452506_A_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MOUSE430_2:1453784_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MOUSE430A_2:1453784_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MOE430A:1453784_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MU11KSUBA:AA597164_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MU11KSUBB:MSA.4917.0_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MU11KSUBB:MSA.22526.0_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MG-U74AV2:96750_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
MG-U74CV2:168309_I_AT integrin-linked kinase-associated serine/threonine phosphatase 2C mm
RG-U34C:RC_AI172528_AT integrin-linked kinase-associated serine/threonine phosphatase 2C rn
RG-U34A:AF095927_AT integrin-linked kinase-associated serine/threonine phosphatase 2C rn
RG-U34A:AF095927_G_AT integrin-linked kinase-associated serine/threonine phosphatase 2C rn
RG-U34B:RC_AA955651_S_AT integrin-linked kinase-associated serine/threonine phosphatase 2C rn
RAE230A:1367921_AT integrin-linked kinase-associated serine/threonine phosphatase 2C rn
RAT230_2:1367921_AT integrin-linked kinase-associated serine/threonine phosphatase 2C rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
8287 protein serine/threonine phosphatase complex inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
4722 protein serine/threonine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04260 Hypothetical protein F33A8.6 [Caenorhabditis elegans] emb|CAA20326.1| Hypothetical protein F33A8.6 [Caenorhabditis elegans] ref|NP_496370.1| F33A8.6 [Caenorhabditis elegans] 1.0E-130
blast CAE59576 Hypothetical protein CBG02976 [Caenorhabditis briggsae] 1.0E-106
blast NP_110395 integrin-linked kinase-associated protein phosphatase 2C isoform 1 [Homo sapiens] emb|CAG38564.1| ILKAP [Homo sapiens] emb|CAB66784.1| hypothetical protein [Homo sapiens] gb|AAH06576.1| Integrin-linked kinase-associated protein phosphatase 2C, isoform 1 [Homo sapiens] gb|AAY24336.1| unknown [Homo sapiens] gb|AAK07736.1| integrin-linked kinase-associated serine/threonine phosphatase 2C [Homo sapiens] 1.0E-42
Protein Domains
Database ID Description E-Value
Pfam IPR001932 EMBL-EBI Protein phosphatase 2C-like 2.6E-40
Sequence
Target Sequence 
>C. ELEGANS:190294_AT
gcaagacactcacataatgcttccaaaattcgatttaggaaccgaaaaatcatttctgtc
tcgtgcatcatttttcgcgatttttgatggtcacgcaggaccacgcgccgcagagcattg
tcagagtcagatgggtaaaacggtcaaagaaaaacttgccaaattttcggatttcccaac
attgactaaatcactcaagcagaccttcacagaatcctacaaagcagtggacgacgggtt
tttggcaattgccaaacagaataaacctatctggaaggatggaaccaccgcgaccaccat
gatcattctgaacaatgtgatctacgtggcaaatattggtgatagtcgagctgttgttgc
tagaaagaaagaagatggatcatttgcaccagtttgtcttactgtagatcacgatccaat
gtctcatgatgaaaggatgagaattcagaaagctggagcagttgtgaaagatggtcgaat
taatggagtaatcgaagtgtctcgttcaattggagatttgccattcaaatcacttggcat
catcagtactccgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCAAGACACTCACATAATGCTTCCA 286 321 150 Antisense
AAAATCATTTCTGTCTCGTGCATCA 454 133 195 Antisense
GTCTCGTGCATCATTTTTCGCGATT 8 471 207 Antisense
CGCCGCAGAGCATTGTCAGAGTCAG 417 257 255 Antisense
AGCAGACCTTCACAGAATCCTACAA 503 77 347 Antisense
GACGACGGGTTTTTGGCAATTGCCA 47 365 379 Antisense
TGGAAGGATGGAACCACCGCGACCA 425 545 421 Antisense
GCGACCACCATGATCATTCTGAACA 289 289 439 Antisense
GATCATTTGCACCAGTTTGTCTTAC 84 421 527 Antisense
GTAGATCACGATCCAATGTCTCATG 89 457 553 Antisense
TCACTTGGCATCATCAGTACTCCGG 452 625 679 Antisense
Sequence Source Affymetrix Proprietary Database