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[190288_at] glutamyl aminopeptidase

Description AC3.5 /REP_DB=WormBase Gene ID /WP=CE05135 /TR=Q17405 /GB=CAA94872.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=glutamyl aminopeptidase
Cluster 6grp_highest_10_10 > 16      6grp_high1_10_10 > 51      4grp_highest_8_8 > 17      4grp_high_8_8 > 61      6grp_highest_nonorm > 53      6grp_total > 51      4grp_total > 59      6grp_highest_sub > 03_04      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 519
1 2 3 4 range
A 558.2
(0.3)
P 		641.5
(3)
P 		637.2
(2.9)
P 		454
(-3)
P 		188
B 659.8
(0)
P 		790.5
(1.5)
P 		917.6
(3)
P 		398.4
(-3)
P 		519
C 600.7
(0.2)
P 		659.6
(1.2)
P 		763.8
(3)
P 		419.9
(-3)
P 		344
avr 606.2
(0.1) 		697.2
(1.7) 		772.9
(3) 		424.1
(-3) 		349

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1062
1 2 3 4 5 6 range
A 734.5
(-0.6)
P 		987.9
(1.3)
P 		1049
(1.8)
P 		1205.7
(3)
P 		595.3
(-1.6)
P 		415.1
(-3)
P 		791
B 641.9
(-1)
P 		633.2
(-1)
P 		993.3
(1.7)
P 		1158.1
(3)
P 		510.2
(-2)
P 		377.6
(-3)
P 		781
C 566.6
(-2.5)
P 		803.9
(-1)
P 		1439.3
(3)
P 		999.2
(0.2)
P 		490.1
(-3)
P 		507.1
(-2.9)
P 		949
avr 647.7
(-1.2) 		808.3
(0.1) 		1160.5
(3) 		1121
(2.7) 		531.9
(-2.2) 		433.3
(-3) 		727
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 200
1 2 3 4 range
A 203.2
(3)
P 		139.2
(0.2)
P 		166.6
(1.4)
P 		66.5
(-3)
P 		137
B 210.4
(2.9)
P 		195.2
(2.2)
P 		212.6
(3)
P 		84.9
(-3)
P 		128
C 198.8
(0.9)
P 		189.6
(0.6)
P 		266.2
(3)
P 		70.8
(-3)
P 		195
avr 204.1
(2.5) 		174.7
(1.3) 		215.1
(3) 		74.1
(-3) 		141

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 265
1 2 3 4 5 6 range
A 135.4
(-2.2)
P 		351.3
(3)
P 		228.4
(0.1)
P 		305.8
(1.9)
P 		179.6
(-1.1)
P 		101.1
(-3)
P 		250
B 223.4
(-0)
P 		210.8
(-0.5)
P 		241.2
(0.6)
P 		306.7
(3)
P 		207.3
(-0.6)
P 		140.8
(-3)
P 		166
C 210
(-1.5)
P 		245.3
(-0.5)
P 		366.3
(3)
P 		200.9
(-1.8)
P 		158.6
(-3)
P 		169.8
(-2.7)
P 		208
avr 189.6
(-0.8) 		269.1
(2.6) 		278.6
(3) 		271.1
(2.7) 		181.8
(-1.1) 		137.2
(-3) 		141
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190288_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11591
Sequence Type Exemplar sequence
Representative Public ID AC3.5 NCBI
Target Description AC3.5 /REP_DB=WormBase Gene ID /WP=CE05135 /TR=Q17405 /GB=CAA94872.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=glutamyl aminopeptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073268(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073268 NCBI Caenorhabditis elegans AC3.5 (AC3.5) mRNA, complete cds. 11/11 None
SNAP00000028837 ENSEMBL cdna:SNAP chromosome:CEL140:V:10391839:10395938:1 11/11 None
GENEFINDER00000028842 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10391109:10395938:1 11/11 None
AC3.5 ENSEMBL cdna:known chromosome:CEL140:V:10391052:10396087:1 gene:AC3.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10391108-10395938(+) 100.0 100.0
Public Domain and Genome References
Gene Title glutamyl aminopeptidase
Ensembl AC3.5
Entrez Gene 179447 Entrez gene
SwissProt Q17405 EMBL-EBI
WormBase CE36372 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4179 membrane alanyl aminopeptidase activity inferred from electronic annotation QuickGO AmiGO
4289 subtilase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94872 Hypothetical protein AC3.5 [Caenorhabditis elegans] ref|NP_505669.2| AC3.5 [Caenorhabditis elegans] 0.0
blast CAE64825 Hypothetical protein CBG09621 [Caenorhabditis briggsae] 0.0
blast CAB57358 microsomal aminopeptidase [Haemonchus contortus] 5.0E-91
Protein Domains
Database ID Description E-Value
Pfam IPR001930 EMBL-EBI Peptidase M1, membrane alanine aminopeptidase 1.0E-126
Pfam IPR001930 EMBL-EBI Peptidase M1, membrane alanine aminopeptidase 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_505669.2 1 80-102
AC3.5 1 80-102
SNAP00000028837 1 68-90
GENEFINDER00000028842 1 80-102
Sequence
Target Sequence 
>C. ELEGANS:190288_AT
tcgctccgtgccaattttctggaaatttcagcagtgactgctcagaggtgccaggggatc
ttcgagagaaggtgtactgcaatggagttgaatttggaaatgacacagtctttgaaacag
tccgcgaacttgccgaaaaggaagtcgatggagccgaaaaagatcttctccaaaattctc
tcgcctgttttagagatccacgtgctctccgtcgcctcattttggataatctcaacagta
cttctacagtaacactactactgagaaaaatgaatagccgtccagttggaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCGCTCCGTGCCAATTTTCTGGAAA 426 599 2612 Antisense
AGCAGTGACTGCTCAGAGGTGCCAG 428 77 2641 Antisense
TCAGAGGTGCCAGGGGATCTTCGAG 580 621 2653 Antisense
ACACAGTCTTTGAAACAGTCCGCGA 651 109 2714 Antisense
CAGTCCGCGAACTTGCCGAAAAGGA 21 199 2729 Antisense
AAGATCTTCTCCAAAATTCTCTCGC 430 155 2771 Antisense
CCAAAATTCTCTCGCCTGTTTTAGA 184 277 2781 Antisense
TTTTAGAGATCCACGTGCTCTCCGT 505 675 2799 Antisense
CTCCGTCGCCTCATTTTGGATAATC 687 233 2818 Antisense
GGATAATCTCAACAGTACTTCTACA 424 511 2835 Antisense
AAATGAATAGCCGTCCAGTTGGAAA 488 109 2879 Antisense
Sequence Source Affymetrix Proprietary Database