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[190286_at] alcohol dehydrogenase

Description C55A6.6 /REP_DB=WormBase Gene ID /WP=CE09003 /TR=O17721 /GB=CAB02866.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=alcohol dehydrogenase
Cluster 6grp_highest_10_10 > 12      6grp_high1_10_10 > 30      4grp_highest_8_8 > 46      4grp_high_8_8 > 10      6grp_highest_nonorm > 51      6grp_total > 45      4grp_total > 14      6grp_high1_sub > 03      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 723
1 2 3 4 range
A 728.4
(2.8)
P 		262.9
(-2.2)
P 		183.2
(-3)
P 		748.5
(3)
P 		565
B 711.7
(1.6)
P 		253.2
(-2.2)
P 		162.1
(-3)
P 		885
(3)
P 		723
C 664.2
(1.7)
P 		209.2
(-2.8)
P 		186.3
(-3)
P 		791.3
(3)
P 		605
avr 701.4
(2) 		241.8
(-2.4) 		177.2
(-3) 		808.3
(3) 		631

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 542
1 2 3 4 5 6 range
A 537.4
(-0.6)
P 		455.6
(-1.5)
P 		862.4
(3)
P 		588.9
(-0)
P 		320.6
(-3)
P 		417.5
(-1.9)
P 		542
B 700.8
(3)
P 		656.8
(2.3)
P 		692.2
(2.9)
P 		410.3
(-1.8)
P 		336.6
(-3)
P 		636.3
(1.9)
P 		364
C 731.9
(3)
P 		554.2
(0.2)
P 		535.4
(-0.1)
P 		525.4
(-0.2)
P 		348.2
(-3)
P 		613.9
(1.2)
P 		384
avr 656.7
(2.3) 		555.5
(0.7) 		696.7
(3) 		508.2
(-0.1) 		335.1
(-3) 		555.9
(0.7) 		362
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 228
1 2 3 4 range
A 265.2
(3)
P 		57.1
(-2.7)
P 		47.9
(-3)
P 		109.6
(-1.3)
P 		217
B 226.9
(3)
P 		62.5
(-2.2)
P 		37.6
(-3)
P 		188.6
(1.8)
P 		189
C 219.9
(3)
P 		60.1
(-3)
P 		64.9
(-2.8)
P 		133.4
(-0.2)
P 		160
avr 237.3
(3) 		59.9
(-2.7) 		50.1
(-3) 		143.9
(0) 		187

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 175
1 2 3 4 5 6 range
A 99.1
(-2.8)
P 		162
(1.3)
P 		187.8
(3)
P 		149.4
(0.5)
P 		96.7
(-3)
P 		101.7
(-2.7)
P 		91
B 243.9
(3)
P 		218.6
(1.9)
P 		168.1
(-0.4)
P 		108.7
(-3)
P 		136.8
(-1.8)
P 		237.3
(2.7)
P 		135
C 271.3
(3)
P 		169.1
(-0.7)
P 		136.3
(-1.9)
P 		105.7
(-3)
P 		112.7
(-2.7)
P 		205.5
(0.6)
P 		166
avr 204.8
(3) 		183.2
(1.6) 		164.1
(0.3) 		121.3
(-2.6) 		115.4
(-3) 		181.5
(1.4) 		89
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190286_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13566
Sequence Type Exemplar sequence
Representative Public ID C55A6.6 NCBI
Target Description C55A6.6 /REP_DB=WormBase Gene ID /WP=CE09003 /TR=O17721 /GB=CAB02866.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=alcohol dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073519(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073519 NCBI Caenorhabditis elegans C55A6.6 (C55A6.6) mRNA, complete cds. 11/11 None
SNAP00000029772 ENSEMBL cdna:SNAP chromosome:CEL140:V:11516422:11518767:-1 11/11 None
GENEFINDER00000029780 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:11516422:11517319:-1 11/11 None
C55A6.6 ENSEMBL cdna:known chromosome:CEL140:V:11516341:11517326:-1 gene:C55A6.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:11516421-11517319(-) 100.0 100.0
Public Domain and Genome References
Gene Title alcohol dehydrogenase
Ensembl C55A6.6
Entrez Gene 183835 Entrez gene
SwissProt O17721 EMBL-EBI
WormBase CE09003 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02866 Hypothetical protein C55A6.6 [Caenorhabditis elegans] ref|NP_505920.1| C55A6.6 [Caenorhabditis elegans] 1.0E-135
blast CAE75267 Hypothetical protein CBG23230 [Caenorhabditis briggsae] 1.0E-109
blast CAB02865 Hypothetical protein C55A6.5 [Caenorhabditis elegans] ref|NP_505921.1| C55A6.5 [Caenorhabditis elegans] pdb|1YO6|F Chain F, Crystal Structure Of The Putative Carbonyl Reductase Sniffer Of Caenorhabditis Elegans pdb|1YO6|E Chain E, Crystal Structure Of The Putative Carbonyl Reductase Sniffer Of Caenorhabditis Elegans pdb|1YO6|D Chain D, Crystal Structure Of The Putative Carbonyl Reductase Sniffer Of Caenorhabditis Elegans pdb|1YO6|C Chain C, Crystal Structure Of The Putative Carbonyl Reductase Sniffer Of Caenorhabditis Elegans pdb|1YO6|B Chain B, Crystal Structure Of The Putative Carbonyl Reductase Sniffer Of Caenorhabditis Elegans pdb|1YO6|A Chain A, Crystal Structure Of The Putative Carbonyl Reductase Sniffer Of Caenorhabditis Elegans 1.0E-109
Protein Domains
Database ID Description E-Value
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 1.1E-16
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 3.0E-18
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 1.1E-16
Sequence
Target Sequence 
>C. ELEGANS:190286_AT
cacatgttcatgttcttccattgatagtaacttgtgataaatcaattgattcttttgtga
caaaagttgaagaaatagttggatctgatggactcaatttacttgtcaacaacgcgggaa
ttgctgtcaaatatctcacaaaaactaaaccaaaccgttcaatgattgctgagcaactag
atgtcaacacaacaagtgttgtgatactaactcaaaaactattaccacttttaacaagag
ctgcatccaaagtttctggagatcaactttccgtttcacgtgctgctgtaatcactatct
catctggactcggatcaattactgaaaacactacaggatcagcagtattcgatagtttgg
catacagaatgagtaaggctgcagttaatatgtttggtaggactttggcaattgatctgc
aagatgatcacattttggtggttaacttttgtccaggatgggttcaaactgatatgggag
ggcaagaagcgatgctcactgtagagcagtccacttctgaactagtttcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CACATGTTCATGTTCTTCCATTGAT 571 195 164 Antisense
GTCAACAACGCGGGAATTGCTGTCA 611 463 268 Antisense
AAACCAAACCGTTCAATGATTGCTG 118 115 310 Antisense
GATTGCTGAGCAACTAGATGTCAAC 152 435 327 Antisense
ACAAGAGCTGCATCCAAAGTTTCTG 498 105 397 Antisense
AACACTACAGGATCAGCAGTATTCG 46 137 490 Antisense
GTAGGACTTTGGCAATTGATCTGCA 569 453 560 Antisense
TGGTGGTTAACTTTTGTCCAGGATG 363 543 599 Antisense
GAGGGCAAGAAGCGATGCTCACTGT 608 401 641 Antisense
GCTCACTGTAGAGCAGTCCACTTCT 381 301 657 Antisense
GCAGTCCACTTCTGAACTAGTTTCC 126 309 669 Antisense
Sequence Source Affymetrix Proprietary Database