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[190283_at] RAS-related protein

Description F53F10.4 /REP_DB=WormBase Gene ID /WP=CE10986 /TR=O01577 /GB=AAB52431.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=RAS-related protein
Cluster 6grp_highest_10_10 > 50      6grp_high1_10_10 > 06      4grp_highest_8_8 > 52      4grp_high_8_8 > 16      6grp_highest_nonorm > 03      6grp_total > 07      4grp_total > 31      6grp_highest_sub > De      6grp_cgc > 21      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1273
1 2 3 4 range
A 3604.3
(3)
P 		2361.3
(-3)
P 		2631.8
(-1.7)
P 		3271
(1.4)
P 		1243
B 3221.4
(3)
P 		2985.9
(-3)
P 		3060.6
(-1.1)
P 		3097.8
(-0.1)
P 		236
C 3633.9
(3)
P 		3425.7
(1.3)
P 		2898
(-3)
P 		3041.1
(-1.8)
P 		736
avr 3486.5
(3) 		2924.3
(-2.4) 		2863.5
(-3) 		3136.6
(-0.4) 		623

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2192
1 2 3 4 5 6 range
A 3382.3
(3)
P 		3011.7
(1.1)
P 		2858.6
(0.3)
P 		2450.1
(-1.8)
P 		2354.9
(-2.3)
P 		2226.3
(-3)
P 		1156
B 3917.1
(3)
P 		2918.1
(-0.6)
P 		3343.3
(1)
P 		2854.7
(-0.8)
P 		2357.9
(-2.6)
P 		2232.7
(-3)
P 		1684
C 4418.1
(3)
P 		2919.5
(-1.3)
P 		2503.7
(-2.5)
P 		2658.7
(-2)
P 		2319.7
(-3)
P 		2374.9
(-2.8)
P 		2098
avr 3905.8
(3) 		2949.8
(-0.5) 		2901.9
(-0.7) 		2654.5
(-1.6) 		2344.2
(-2.8) 		2278
(-3) 		1628
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 834
1 2 3 4 range
A 1312.3
(3)
P 		512.6
(-2.8)
P 		688
(-1.5)
P 		478.8
(-3)
P 		834
B 1027.3
(3)
P 		737.4
(-1.7)
P 		709.2
(-2.2)
P 		660.1
(-3)
P 		367
C 1202.9
(3)
P 		984.9
(1.1)
P 		1010
(1.3)
P 		512.8
(-3)
P 		690
avr 1180.8
(3) 		745
(-1.1) 		802.4
(-0.6) 		550.6
(-3) 		630

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1103
1 2 3 4 5 6 range
A 623.5
(-2.1)
P 		1071.1
(3)
P 		622.5
(-2.1)
P 		621.4
(-2.1)
P 		710.6
(-1.1)
P 		542
(-3)
P 		529
B 1363
(3)
P 		971.3
(-0.9)
P 		811.9
(-2.4)
P 		756.1
(-3)
P 		958
(-1)
P 		832.6
(-2.2)
P 		607
C 1637.6
(3)
P 		890.8
(-1.1)
P 		637.2
(-2.4)
P 		534.7
(-3)
P 		750.6
(-1.8)
P 		795
(-1.6)
P 		1103
avr 1208
(3) 		977.7
(0.6) 		690.5
(-2.4) 		637.4
(-3) 		806.4
(-1.2) 		723.2
(-2.1) 		571
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190283_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.218
Sequence Type Exemplar sequence
Representative Public ID F53F10.4 NCBI
Target Description F53F10.4 /REP_DB=WormBase Gene ID /WP=CE10986 /TR=O01577 /GB=AAB52431.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=RAS-related protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058832(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058832 NCBI Caenorhabditis elegans UNCoordinated family member (unc-108) (unc-108) mRNA, complete cds. 11/11 A 
SNAP00000021854 ENSEMBL cdna:SNAP chromosome:CEL140:I:3824953:3826045:1 11/11 None
GENEFINDER00000021865 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:3824953:3826045:1 11/11 None
F53F10.4.2 ENSEMBL cdna:known chromosome:CEL140:I:3824948:3826508:1 gene:F53F10.4 11/11 None
F53F10.4.1 ENSEMBL cdna:known chromosome:CEL140:I:3824949:3826516:1 gene:F53F10.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:3824952-3826045(+) 100.0 100.0
Public Domain and Genome References
Gene Title RAS-related protein
Gene Symbol unc-108
Ensembl F53F10.4
Entrez Gene 171956 Entrez gene
SwissProt O01577 EMBL-EBI
WormBase CE10986 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:17949_S_AT Rab2-like GTP-binding protein (RAB2) at
ATGENOME1:17948_I_AT Rab2-like GTP-binding protein (RAB2) at
ATH1-121501:245407_AT Rab2-like GTP-binding protein (RAB2) at
CANINE:1582711_S_AT RAB2, member RAS oncogene family cfa
CANINE_2:CFA.3880.1.A1_S_AT RAB2, member RAS oncogene family cfa
CANINE_2:CFA.3880.1.A2_AT RAB2, member RAS oncogene family cfa
CANINE:1587782_AT RAB2, member RAS oncogene family cfa
CANINE:1594278_AT RAB2, member RAS oncogene family cfa
DROSOPHILA_2:1636607_AT Rab-protein 2 dm
DROSGENOME1:151803_AT Rab-protein 2 dm
CHICKEN:GGA.13000.1.S1_AT RAB2, member RAS oncogene family gga
CHICKEN:GGA.4794.1.S1_AT RAB2, member RAS oncogene family gga
HG-U133_PLUS_2:208733_AT RAB2, member RAS oncogene family hs
HG-U133A_2:208733_AT RAB2, member RAS oncogene family hs
HG-U133A:208733_AT RAB2, member RAS oncogene family hs
HG-U133_PLUS_2:208731_AT RAB2, member RAS oncogene family hs
HG-U133A_2:208731_AT RAB2, member RAS oncogene family hs
HG-U133A:208731_AT RAB2, member RAS oncogene family hs
HG-U133A:208734_X_AT RAB2, member RAS oncogene family hs
HG-U133_PLUS_2:208734_X_AT RAB2, member RAS oncogene family hs
HG-U133A_2:208734_X_AT RAB2, member RAS oncogene family hs
HG-U133_PLUS_2:208730_X_AT RAB2, member RAS oncogene family hs
HG-U133A_2:208730_X_AT RAB2, member RAS oncogene family hs
HG-U133A:208730_X_AT RAB2, member RAS oncogene family hs
HU35KSUBD:RC_R38819_AT RAB2, member RAS oncogene family hs
HG-U95AV2:623_S_AT RAB2, member RAS oncogene family hs
HC-G110:623_S_AT RAB2, member RAS oncogene family hs
HUGENEFL:X12953_AT RAB2, member RAS oncogene family hs
HUGENEFL:M28213_S_AT RAB2, member RAS oncogene family hs
U133_X3P:G550061_3P_A_AT RAB2, member RAS oncogene family hs
U133_X3P:HS.78305.0.A5_3P_AT RAB2, member RAS oncogene family hs
U133_X3P:HS.78305.0.A3_3P_AT RAB2, member RAS oncogene family hs
U133_X3P:HS.78305.0.A1_3P_AT RAB2, member RAS oncogene family hs
HG-U133_PLUS_2:208732_AT RAB2, member RAS oncogene family hs
HG-U133A_2:208732_AT RAB2, member RAS oncogene family hs
HG-FOCUS:208732_AT RAB2, member RAS oncogene family hs
HG-U133A:208732_AT RAB2, member RAS oncogene family hs
HU35KSUBD:RC_AA479949_AT RAB2, member RAS oncogene family hs
U133_X3P:HS.78305.0.A4_3P_AT RAB2, member RAS oncogene family hs
HG-U95AV2:32581_AT RAB2, member RAS oncogene family hs
HG-U133A_2:221960_S_AT RAB2, member RAS oncogene family hs
HG-U133_PLUS_2:221960_S_AT RAB2, member RAS oncogene family hs
HG-U133A:221960_S_AT RAB2, member RAS oncogene family hs
HG-U95D:67490_AT RAB2, member RAS oncogene family hs
HG-U95D:75891_AT RAB2, member RAS oncogene family hs
U133_X3P:HS.78305.1.A1_3P_A_AT RAB2, member RAS oncogene family hs
MOUSE430A_2:1436477_X_AT RAB2, member RAS oncogene family mm
MOE430A:1436477_X_AT RAB2, member RAS oncogene family mm
MOUSE430_2:1436477_X_AT RAB2, member RAS oncogene family mm
MU11KSUBA:C80220_RC_AT RAB2, member RAS oncogene family mm
MU11KSUBB:X95403_S_AT RAB2, member RAS oncogene family mm
MG-U74AV2:94031_AT RAB2, member RAS oncogene family mm
MG-U74AV2:162141_R_AT RAB2, member RAS oncogene family mm
MOE430A:1419945_S_AT RAB2, member RAS oncogene family mm
MOUSE430A_2:1419945_S_AT RAB2, member RAS oncogene family mm
MOUSE430_2:1419945_S_AT RAB2, member RAS oncogene family mm
MOE430A:1418621_AT RAB2, member RAS oncogene family mm
MOUSE430A_2:1418621_AT RAB2, member RAS oncogene family mm
MOUSE430_2:1418621_AT RAB2, member RAS oncogene family mm
MOE430A:1418622_AT RAB2, member RAS oncogene family mm
MOUSE430A_2:1418622_AT RAB2, member RAS oncogene family mm
MOUSE430_2:1418622_AT RAB2, member RAS oncogene family mm
MOE430A:1418623_AT RAB2, member RAS oncogene family mm
MOUSE430A_2:1418623_AT RAB2, member RAS oncogene family mm
MOUSE430_2:1418623_AT RAB2, member RAS oncogene family mm
MOE430A:1419946_S_AT RAB2, member RAS oncogene family (Rab2), mRNA mm
MOUSE430A_2:1419946_S_AT RAB2, member RAS oncogene family (Rab2), mRNA mm
MOUSE430_2:1419946_S_AT RAB2, member RAS oncogene family (Rab2), mRNA mm
MOE430A:1449676_AT RAB2, member RAS oncogene family (Rab2), mRNA mm
MOUSE430A_2:1449676_AT RAB2, member RAS oncogene family (Rab2), mRNA mm
MOUSE430_2:1449676_AT RAB2, member RAS oncogene family (Rab2), mRNA mm
MU19KSUBB:TC30361_AT RAB2, member RAS oncogene family (Rab2), mRNA mm
RG-U34C:RC_AI237381_AT RAB2, member RAS oncogene family rn
RAE230A:1370087_AT RAB2, member RAS oncogene family rn
RAT230_2:1370087_AT RAB2, member RAS oncogene family rn
RG-U34A:RC_AI009095_AT RAB2, member RAS oncogene family rn
RAE230B:1392681_AT RAB2, member RAS oncogene family rn
RAT230_2:1392681_AT RAB2, member RAS oncogene family rn
RG-U34C:RC_AI112132_AT RAB2, member RAS oncogene family rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
160 two-component signal transduction system (phosphorelay) inferred from electronic annotation QuickGO AmiGO
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
6886 intracellular protein transport inferred from electronic annotation QuickGO AmiGO
7264 small GTPase mediated signal transduction inferred from electronic annotation QuickGO AmiGO
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB52431 Uncoordinated protein 108 [Caenorhabditis elegans] ref|NP_491233.1| UNCoordinated family member (unc-108) [Caenorhabditis elegans] 1.0E-102
blast CAE66672 Hypothetical protein CBG12011 [Caenorhabditis briggsae] 1.0E-101
Protein Domains
Database ID Description E-Value
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 3.2E-100
Sequence
Target Sequence 
>C. ELEGANS:190283_AT
gccggacaagaatcattccgctccatcactcgttcctattatcgtggagccgccggagct
cttctcgtctacgacattacacgacgcgacacattcaatcatttgacatcttggcttgag
gatgccaggcagcacagtaattccaatatggttattatgttgattggaaataagagtgac
ctggaagcccgtcgcgaagtgaaacgtgaagagggagaagcattcgcacgagagcacgga
ctcgtattcatggagacatctgccaagacggctgccaacgtggaagaggcgttcatcgac
actgccaaagagatctaccgtaagattcaagaaggcgtgttcgacattaacaatgaggca
aacggaatcaagttgggaccacagcactctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCCGGACAAGAATCATTCCGCTCCA 606 283 199 Antisense
TCCATCACTCGTTCCTATTATCGTG 299 591 220 Antisense
GCTCTTCTCGTCTACGACATTACAC 545 299 256 Antisense
ACACGACGCGACACATTCAATCATT 116 109 277 Antisense
GGATGCCAGGCAGCACAGTAATTCC 91 513 318 Antisense
ATAAGAGTGACCTGGAAGCCCGTCG 85 23 368 Antisense
GAAGCATTCGCACGAGAGCACGGAC 580 341 415 Antisense
GAGAGCACGGACTCGTATTCATGGA 551 393 428 Antisense
TGCCAAGACGGCTGCCAACGTGGAA 628 579 459 Antisense
GAAGAGGCGTTCATCGACACTGCCA 612 337 481 Antisense
ATCAAGTTGGGACCACAGCACTCTC 432 25 565 Antisense
Sequence Source Affymetrix Proprietary Database