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[190282_at] carbonic anhydrase

Description R173.1 /REP_DB=WormBase Gene ID /WP=CE04844 /TR=SW:Q10462 /GB=AAA80437.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=carbonic anhydrase
Cluster 6grp_highest_10_10 > 41      6grp_high1_10_10 > 15      4grp_highest_8_8 > 32      4grp_high_8_8 > 51      6grp_highest_nonorm > 60      6grp_total > 15      4grp_total > 60      6grp_highest_sub > De      6grp_cgc > 32      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 948
1 2 3 4 range
A 829.1
(1.9)
P
969.4
(3)
P
925.9
(2.7)
P
182.2
(-3)
P
787
B 1126.7
(3)
P
971.7
(2)
P
981.1
(2.1)
P
195.2
(-3)
P
932
C 1084.4
(3)
P
942.7
(2.1)
P
847.5
(1.4)
P
178.6
(-3)
P
906
avr 1013.4
(3)
961.3
(2.6)
918.2
(2.3)
185.3
(-3)
828

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 616
1 2 3 4 5 6 range
A 745
(3)
P
715.7
(2.7)
P
291.7
(-2)
P
291.8
(-2)
P
322.3
(-1.7)
P
203.1
(-3)
P
542
B 603.8
(3)
P
597.5
(2.9)
P
319.5
(-1.7)
P
284.6
(-2.3)
P
321.1
(-1.7)
P
239.4
(-3)
P
364
C 596.3
(2.6)
P
628.4
(3)
P
327.1
(-0.6)
P
275.1
(-1.2)
P
361.1
(-0.2)
P
128.9
(-3)
P
500
avr 648.4
(3)
647.2
(3)
312.8
(-1.4)
283.8
(-1.8)
334.8
(-1.1)
190.5
(-3)
458
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 333
1 2 3 4 range
A 301.9
(3)
P
210.4
(1)
P
242.1
(1.7)
P
26.7
(-3)
P
275
B 359.3
(3)
P
240
(0.7)
P
227.3
(0.5)
P
41.6
(-3)
P
318
C 359
(3)
P
271
(1.4)
P
295.4
(1.8)
P
30.1
(-3)
P
329
avr 340.1
(3)
240.5
(1.1)
254.9
(1.3)
32.8
(-3)
307

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 212
1 2 3 4 5 6 range
A 137.3
(-0.4)
P
254.6
(3)
P
63.5
(-2.6)
P
74
(-2.3)
P
97.2
(-1.6)
P
49.4
(-3)
P
205
B 210.1
(3)
P
198.9
(2.5)
P
77.6
(-2.9)
P
75.4
(-3)
P
130.5
(-0.5)
P
89.3
(-2.4)
P
135
C 221
(3)
P
191.7
(2)
P
83.3
(-1.6)
P
55.3
(-2.6)
P
116.9
(-0.5)
P
43.1
(-3)
P
178
avr 189.5
(2)
215.1
(3)
74.8
(-2.4)
68.2
(-2.7)
114.9
(-0.9)
60.6
(-3)
155
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190282_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16359
Sequence Type Exemplar sequence
Representative Public ID R173.1 NCBI
Target Description R173.1 /REP_DB=WormBase Gene ID /WP=CE04844 /TR=SW:Q10462 /GB=AAA80437.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=carbonic anhydrase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076785(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_076785 NCBI Caenorhabditis elegans Carbonic AnHydrase family member (cah-5) (cah-5) mRNA, complete cds. 11/11 None
GENEFINDER00000027999 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:7019436:7023797:1 11/11 None
SNAP00000027996 ENSEMBL cdna:SNAP chromosome:CEL140:X:7021953:7023797:1 11/11 None
R173.1 ENSEMBL cdna:known chromosome:CEL140:X:7019978:7023881:1 gene:R173.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:7019980-7023796(+) 98.81 98.81
Public Domain and Genome References
Gene Title carbonic anhydrase
Gene Symbol cah-5
Ensembl R173.1
Entrez Gene 180972 Entrez gene
SwissProt Q10462 EMBL-EBI
WormBase CE36560 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.31230.1.S1_AT similar to Carbonic anhydrase VII (Carbonate dehydratase VII) (CA-VII) cfa
CHICKEN:GGAAFFX.3310.1.S1_AT similar to Carbonic anhydrase VII (Carbonate dehydratase VII) (CA-VII) gga
CHICKEN:GGAAFFX.3310.1.S1_S_AT similar to Carbonic anhydrase VII (Carbonate dehydratase VII) (CA-VII) gga
CHICKEN:GGAAFFX.3310.2.S1_AT similar to Carbonic anhydrase VII (Carbonate dehydratase VII) (CA-VII) gga
HG-U95AV2:34572_AT carbonic anhydrase VII hs
HG-U133_PLUS_2:207504_AT carbonic anhydrase VII hs
HG-U133A:207504_AT carbonic anhydrase VII hs
HG-FOCUS:207504_AT carbonic anhydrase VII hs
HG-U133A_2:207504_AT carbonic anhydrase VII hs
HU35KSUBC:RC_N62608_S_AT carbonic anhydrase VII hs
HUGENEFL:M76424_AT carbonic anhydrase VII hs
U133_X3P:G4885100_3P_AT carbonic anhydrase VII hs
HG-U95B:47673_S_AT carbonic anhydrase VII hs
MOE430A:1452484_AT carbonic anhydrase 7 mm
MOUSE430_2:1452484_AT carbonic anhydrase 7 mm
MOUSE430A_2:1452484_AT carbonic anhydrase 7 mm
MG-U74CV2:167479_AT carbonic anhydrase 7 mm
MOE430B:1434973_AT carbonic anhydrase 7 mm
MOUSE430_2:1434973_AT carbonic anhydrase 7 mm
MOE430B:1443824_S_AT carbonic anhydrase 7 mm
MOUSE430_2:1443824_S_AT carbonic anhydrase 7 mm
RG-U34B:RC_AI045537_AT carbonic anhydrase 7 (predicted) rn
RAE230A:1377085_AT carbonic anhydrase 7 (predicted) rn
RAT230_2:1377085_AT carbonic anhydrase 7 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6730 one-carbon compound metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4089 carbonate dehydratase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA80437 Carbonic anhydrase protein 5 [Caenorhabditis elegans] ref|NP_509186.3| Carbonic AnHydrase family member (cah-5) [Caenorhabditis elegans] sp|Q10462|CAH5_CAEEL Putative carbonic anhydrase 5 precursor (Carbonate dehydratase 5) 1.0E-166
blast AAA80437 Carbonic anhydrase protein 5 [Caenorhabditis elegans] ref|NP_509186.3| Carbonic AnHydrase family member (cah-5) [Caenorhabditis elegans] sp|Q10462|CAH5_CAEEL Putative carbonic anhydrase 5 precursor (Carbonate dehydratase 5) 1.0E-120
blast CAE69965 Hypothetical protein CBG16360 [Caenorhabditis briggsae] 8.0E-36
blast CAE69965 Hypothetical protein CBG16360 [Caenorhabditis briggsae] 1.0E-35
blast AAB52498 Carbonic anhydrase protein 3 [Caenorhabditis elegans] ref|NP_510674.1| Carbonic AnHydrase family member (cah-3) [Caenorhabditis elegans] sp|Q27504|CAH3_CAEEL Putative carbonic anhydrase 3 (Carbonate dehydratase 3) 2.0E-35
Protein Domains
Database ID Description E-Value
Pfam IPR001148 EMBL-EBI Carbonic anhydrase, eukaryotic 2.4E-56
Pfam IPR001148 EMBL-EBI Carbonic anhydrase, eukaryotic 2.4E-56
Pfam IPR001148 EMBL-EBI Carbonic anhydrase, eukaryotic 1.0E-52
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509186.3 1 287-309
R173.1 1 287-309
GENEFINDER00000027999 1 341-363
SNAP00000027996 2 4-21,216-238
Sequence
Target Sequence
>C. ELEGANS:190282_AT
gacgctgtcggatcagaacatgctatgggatccttgcattatccagctgagctacacttg
gttcatgttcgcgaaggtttaactctaaaagaagcactttcccgacctgatggcctggct
gtagttggtgtattccttgcaaaaaccaatgatccagttgccaacaaattttccccaatt
tccgaaagacttcacgatctgagacactctggcaataaaacagagttaaagaacttccgt
accaaatatgtcttgccactagacacggaagcgttctatcgctatgaaggaagtctcacg
accccagactgcagtgaagctgttatctggacagtgcttgccgagccaatggcgatctcc
agtcaccagcttcacctccttcgtcaattgcacaacaaggagctagtaaagtcggataaa
aattaccgcccccttcagcctctgaacggccgtcgcatccagtacagaccaagcaaactt
gaccgagccatgatctgctcttcttttgccacaacttcggtta


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
GACGCTGTCGGATCAGAACATGCTA 375 381 454 Antisense
ATCCTTGCATTATCCAGCTGAGCTA 514 39 483 Antisense
GCTACACTTGGTTCATGTTCGCGAA 298 303 504 Antisense
GATGGCCTGGCTGTAGTTGGTGTAT 267 407 562 Antisense
CAGTTGCCAACAAATTTTCCCCAAT 215 207 608 Antisense
ATGAAGGAAGTCTCACGACCCCAGA 376 43 737 Antisense
ACGACCCCAGACTGCAGTGAAGCTG 158 93 751 Antisense
TTATCTGGACAGTGCTTGCCGAGCC 155 681 776 Antisense
TTGCCGAGCCAATGGCGATCTCCAG 522 701 791 Antisense
TGACCGAGCCATGATCTGCTCTTCT 340 569 933 Antisense
TCTTCTTTTGCCACAACTTCGGTTA 676 613 952 Antisense
Sequence Source Affymetrix Proprietary Database