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[190270_at] protease inhibitor

Description T21D12.12 /REP_DB=WormBase Gene ID /WP=CE18275 /TR=O16784 /GB=AAC48097.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protease inhibitor
Cluster 6grp_highest_10_10 > 19      6grp_high1_10_10 > 92      4grp_highest_8_8 > 50      4grp_high_8_8 > 40      6grp_highest_nonorm > 55      6grp_total > 94      4grp_total > 46      6grp_highest_sub > 05      6grp_high1_sub > 04_05      6grp_total_sub > Hat      6grp_rule_based > S5      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1507
1 2 3 4 range
A 2958.9
(3)
P 		1993.9
(-1.7)
P 		1895.2
(-2.2)
P 		1725.1
(-3)
P 		1234
B 3119.4
(3)
P 		2131.1
(-0.9)
P 		2161.6
(-0.8)
P 		1612.9
(-3)
P 		1507
C 2488.6
(3)
P 		1945.3
(-1)
P 		1670.1
(-3)
P 		1948.6
(-1)
P 		819
avr 2855.6
(3) 		2023.4
(-1.6) 		1909
(-2.2) 		1762.2
(-3) 		1093

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1852
1 2 3 4 5 6 range
A 1442.3
(-2.8)
P 		1622.5
(-2.2)
P 		1403.2
(-3)
P 		2440.6
(1)
P 		2961.5
(3)
P 		1914.5
(-1)
P 		1558
B 1122.8
(-3)
P 		1264.7
(-2.5)
P 		1178.9
(-2.8)
P 		2340.7
(0.9)
P 		2974.9
(3)
P 		1535.5
(-1.7)
P 		1852
C 1166.2
(-3)
P 		1495.9
(-1.8)
P 		1850.5
(-0.5)
P 		1584.7
(-1.4)
P 		2777
(3)
P 		2188.4
(0.8)
P 		1611
avr 1243.8
(-3) 		1461
(-2.2) 		1477.5
(-2.2) 		2122
(0.2) 		2904.5
(3) 		1879.5
(-0.7) 		1661
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 825
1 2 3 4 range
A 1077.3
(3)
P 		432.8
(-1.7)
P 		495.4
(-1.2)
P 		252.5
(-3)
P 		825
B 994.7
(3)
P 		526.3
(-1.3)
P 		500.9
(-1.6)
P 		343.7
(-3)
P 		651
C 823.8
(3)
P 		559.3
(-0.2)
P 		582.1
(0.1)
P 		328.6
(-3)
P 		495
avr 965.3
(3) 		506.1
(-1.2) 		526.1
(-1) 		308.3
(-3) 		657

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 943
1 2 3 4 5 6 range
A 265.9
(-3)
P 		577
(-0)
P 		305.6
(-2.6)
P 		619
(0.4)
P 		893.7
(3)
P 		466.1
(-1.1)
P 		628
B 390.7
(-2.3)
P 		421
(-2.1)
P 		286.3
(-3)
P 		620
(-0.8)
P 		1208.7
(3)
P 		572.6
(-1.1)
P 		922
C 432.3
(-1.8)
P 		456.5
(-1.6)
P 		471
(-1.4)
P 		318.7
(-3)
P 		898.6
(3)
P 		732.6
(1.3)
P 		580
avr 363
(-2.9) 		484.8
(-1.8) 		354.3
(-3) 		519.2
(-1.5) 		1000.3
(3) 		590.4
(-0.8) 		646
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190270_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10634
Sequence Type Exemplar sequence
Representative Public ID T21D12.12 NCBI
Target Description T21D12.12 /REP_DB=WormBase Gene ID /WP=CE18275 /TR=O16784 /GB=AAC48097.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protease inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067491(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067491 NCBI Caenorhabditis elegans T21D12.12 (T21D12.12) mRNA, complete cds. 11/11 None
SNAP00000019186 ENSEMBL cdna:SNAP chromosome:CEL140:IV:266451:268271:1 11/11 None
GENEFINDER00000019194 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:266451:268271:1 11/11 None
T21D12.12 ENSEMBL cdna:known chromosome:CEL140:IV:266448:268321:1 gene:T21D12.12 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:266450-268271(+) 100.0 100.0
Public Domain and Genome References
Gene Title protease inhibitor
Ensembl T21D12.12
Entrez Gene 188695 Entrez gene
SwissProt O16784 EMBL-EBI
WormBase CE18275 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC48097 Hypothetical protein T21D12.12 [Caenorhabditis elegans] ref|NP_499892.1| T21D12.12 [Caenorhabditis elegans] 1.0E-102
blast CAE74732 Hypothetical protein CBG22550 [Caenorhabditis briggsae] 6.0E-84
blast CAA98461 Hypothetical protein F35B12.4 [Caenorhabditis elegans] ref|NP_505943.1| F35B12.4 [Caenorhabditis elegans] 6.0E-36
Protein Domains
Database ID Description E-Value
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 5.3E-23
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.8E-19
Sequence
Target Sequence 
>C. ELEGANS:190270_AT
ttgtttttccgctcgcgatactggaaattctggatgtggtcagcagggagcccgctcatt
ttatttccacaagaatacccgcacatgtcagccatttttctatcagggatgcgacggcaa
ctccaatcgattccaatcgaaagaggcttgtgaatcagcttgccggaacgcgactgcttc
tgacgatttagcttacgctgtatgtccatctggagcatacccagctggagccacttctgg
tcagactgttggatgttcgaattgcccacatggttacgagtgtcaaaatcaacaatgctg
tccaacaaaagaaaacacatgtagtttgcagtacgacgctggaaaattcggatctagtgg
aaaacatacacccagatatttcttctcaaagtcctacaagaactgcatgctgttcacttt
ctatggccgcgatggaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGTTTTTCCGCTCGCGATACTGGA 422 705 78 Antisense
AGCAGGGAGCCCGCTCATTTTATTT 569 73 119 Antisense
CGCACATGTCAGCCATTTTTCTATC 146 255 157 Antisense
ATGCGACGGCAACTCCAATCGATTC 100 43 186 Antisense
TTGTGAATCAGCTTGCCGGAACGCG 363 709 225 Antisense
ACGCGACTGCTTCTGACGATTTAGC 233 91 245 Antisense
TTAGCTTACGCTGTATGTCCATCTG 304 681 265 Antisense
GTCCATCTGGAGCATACCCAGCTGG 519 477 281 Antisense
GAGCCACTTCTGGTCAGACTGTTGG 23 385 305 Antisense
CATACACCCAGATATTTCTTCTCAA 15 215 442 Antisense
TTCACTTTCTATGGCCGCGATGGAA 348 687 490 Antisense
Sequence Source Affymetrix Proprietary Database