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[190259_at] Src homology domain 2

Description C48G7.2 /REP_DB=WormBase Gene ID /WP=CE08826 /TR=Q18702 /GB=CAB01493.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Src homology domain 2
Cluster 6grp_total > 47      4grp_total > 44      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 85
1 2 3 4 range
A 117.8
(3)
A 		78.9
(-3)
A 		81.6
(-2.6)
A 		80.8
(-2.7)
A 		39
B 91.6
(0.1)
A 		133.2
(3)
A 		61.9
(-2)
A 		48
(-3)
A 		85
C 96.7
(-1.6)
A 		133.3
(3)
A 		98.3
(-1.4)
A 		86
(-3)
A 		47
avr 102
(1.2) 		115.1
(3) 		80.6
(-1.8) 		71.6
(-3) 		44

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 113
1 2 3 4 5 6 range
A 70.1
(-1)
A 		106.1
(0.9)
A 		32.3
(-3)
A 		68.1
(-1.1)
A 		85.9
(-0.2)
A 		145.5
(3)
A 		113
B 123.5
(3)
A 		89.6
(0.7)
A 		72.9
(-0.5)
A 		53.1
(-1.8)
A 		36.1
(-3)
A 		101.6
(1.5)
A 		87
C 57
(-3)
A 		99.4
(3)
A 		57.1
(-3)
A 		63.9
(-2)
A 		81
(0.4)
A 		65.1
(-1.9)
A 		42
avr 83.5
(0.5) 		98.4
(2.3) 		54.1
(-3) 		61.7
(-2.1) 		67.7
(-1.4) 		104.1
(3) 		50
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 33
1 2 3 4 range
A 42.9
(3)
A 		17.1
(-2)
A 		21.3
(-1.2)
A 		11.8
(-3)
A 		31
B 29.2
(2)
A 		32.9
(3)
A 		14.3
(-1.9)
A 		10.2
(-3)
A 		23
C 32
(1.4)
A 		38.3
(3)
A 		34.3
(2)
A 		14.5
(-3)
A 		24
avr 34.7
(3) 		29.4
(1.6) 		23.3
(-0) 		12.2
(-3) 		23

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 36
1 2 3 4 5 6 range
A 12.9
(-1.8)
A 		37.7
(3)
A 		7
(-3)
A 		17.3
(-1)
A 		25.9
(0.7)
A 		35.4
(2.6)
A 		31
B 43
(3)
A 		29.8
(0.3)
A 		17.7
(-2.3)
A 		14.1
(-3)
A 		14.6
(-2.9)
A 		37.9
(1.9)
A 		29
C 21.1
(-0.2)
A 		30.3
(3)
A 		14.5
(-2.4)
A 		12.9
(-3)
A 		26.2
(1.6)
A 		21.8
(0.1)
A 		17
avr 25.7
(0.9) 		32.6
(3) 		13.1
(-3) 		14.8
(-2.5) 		22.2
(-0.2) 		31.7
(2.7) 		20
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190259_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13985
Sequence Type Exemplar sequence
Representative Public ID C48G7.2 NCBI
Target Description C48G7.2 /REP_DB=WormBase Gene ID /WP=CE08826 /TR=Q18702 /GB=CAB01493.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Src homology domain 2
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074251(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074251 NCBI Caenorhabditis elegans C48G7.2 (C48G7.2) mRNA, complete cds. 11/11 None
SNAP00000031747 ENSEMBL cdna:SNAP chromosome:CEL140:V:14811051:14814037:-1 11/11 None
GENEFINDER00000031749 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:14810511:14818133:-1 11/11 None
C48G7.2 ENSEMBL cdna:known chromosome:CEL140:V:14811051:14817893:-1 gene:C48G7.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:14811050-14817893(-) 100.0 100.0
Public Domain and Genome References
Gene Title Src homology domain 2
Ensembl C48G7.2
Entrez Gene 183584 Entrez gene
SwissProt Q18702 EMBL-EBI
WormBase CE08826 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01493 Hypothetical protein C48G7.2 [Caenorhabditis elegans] ref|NP_506652.1| C48G7.2 [Caenorhabditis elegans] 0.0
blast CAE66363 Hypothetical protein CBG11620 [Caenorhabditis briggsae] 1.0E-150
blast CAE66363 Hypothetical protein CBG11620 [Caenorhabditis briggsae] 1.0E-145
blast CAB01493 Hypothetical protein C48G7.2 [Caenorhabditis elegans] ref|NP_506652.1| C48G7.2 [Caenorhabditis elegans] 1.0E-111
blast CAE66363 Hypothetical protein CBG11620 [Caenorhabditis briggsae] 2.0E-94
blast EAA08210 ENSANGP00000003034 [Anopheles gambiae str. PEST] ref|XP_312446.2| ENSANGP00000003034 [Anopheles gambiae str. PEST] 3.0E-17
blast EAA08210 ENSANGP00000003034 [Anopheles gambiae str. PEST] ref|XP_312446.2| ENSANGP00000003034 [Anopheles gambiae str. PEST] 1.0E-16
Protein Domains
Database ID Description E-Value
Pfam IPR000980 EMBL-EBI SH2 motif 1.2E-7
Pfam IPR000980 EMBL-EBI SH2 motif 0.0039
Pfam IPR000980 EMBL-EBI SH2 motif 1.2E-7
Pfam IPR000980 EMBL-EBI SH2 motif 0.0039
Pfam IPR000980 EMBL-EBI SH2 motif 1.2E-7
Pfam IPR000980 EMBL-EBI SH2 motif 0.0039
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000031749 1 554-576
Sequence
Target Sequence 
>C. ELEGANS:190259_AT
gtgtttactcggatttcgtgctcaaaaggaattcgtcgacgtcgtcaatgtctgggaaga
gtgtcactttgttggaacaaattatacgaacacacgcagtttggtatcttccacacatgg
gtcgaccagaagttctccatctccttcgccgaatggaaccgggaaacttcattgtcagag
catcgacacgcgagaattgcatggctctttcagttcggctggctccgggagctcacgtcg
aaattgatcattatataatcgagaagctcgtcgttccactgaaaccgacaacatcaaaag
aacctgcagctcctacaactgctaaagcggtcaggctagaaggaagccctctcacatttc
gatcacttcctcttctcattgaacattattgtgttaacgaaaattattacaatttatttt
cgttgataatttcagtatcacgaaaaaaaaaatctgaaaacttgaatttcgaaaaccgga
aaaattacaagaaactttcagacgaactagagcaccgtctccaacttccatcggcaatcc
gtgcat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGTTTACTCGGATTTCGTGCTCAA 166 485 830 Antisense
CGTCGACGTCGTCAATGTCTGGGAA 673 245 863 Antisense
GAACACACGCAGTTTGGTATCTTCC 240 353 917 Antisense
ATCTTCCACACATGGGTCGACCAGA 654 29 935 Antisense
CATCTCCTTCGCCGAATGGAACCGG 615 211 967 Antisense
GACACGCGAGAATTGCATGGCTCTT 164 367 1014 Antisense
AGCTCGTCGTTCCACTGAAACCGAC 362 77 1094 Antisense
ACATCAAAAGAACCTGCAGCTCCTA 640 101 1120 Antisense
AGCTCCTACAACTGCTAAAGCGGTC 394 79 1137 Antisense
CTAGAAGGAAGCCCTCTCACATTTC 548 197 1165 Antisense
CAACTTCCATCGGCAATCCGTGCAT 363 187 1351 Antisense
Sequence Source Affymetrix Proprietary Database