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[190251_s_at] protease

Description CD4.6 /REP_DB=WormBase Gene ID /WP=CE16954 /GEN=pas-6 /TR=SW:O44156 /GB=AAB88344.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=protease
Cluster 6grp_highest_10_10 > 46      6grp_high1_10_10 > 63      4grp_highest_8_8 > 10      4grp_high_8_8 > 54      6grp_highest_nonorm > 47      6grp_total > 63      4grp_total > 57      6grp_cgc > 91      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4078
1 2 3 4 range
A 3720.7
(-1.6)
P 		5935.5
(2.1)
P 		6491.5
(3)
P 		2873.9
(-3)
P 		3618
B 3708.3
(-3)
P 		6172.3
(1.6)
P 		6952.1
(3)
P 		3781.2
(-2.9)
P 		3244
C 3708.5
(-1.7)
P 		4702.5
(0.6)
P 		5712.6
(3)
P 		3163.6
(-3)
P 		2549
avr 3712.5
(-2.2) 		5603.4
(1.5) 		6385.4
(3) 		3272.9
(-3) 		3113

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1406
1 2 3 4 5 6 range
A 3434.2
(-0.9)
P 		3281.3
(-3)
P 		3716.3
(3)
P 		3406.2
(-1.3)
P 		3592
(1.3)
P 		3536.1
(0.5)
P 		435
B 3219.5
(-3)
P 		3385.7
(-2.3)
P 		4625.9
(3)
P 		3790.3
(-0.6)
P 		3304.7
(-2.6)
P 		3570.3
(-1.5)
P 		1406
C 3381
(-3)
P 		3511
(-0.1)
P 		3649.7
(3)
P 		3506.8
(-0.2)
P 		3436.9
(-1.8)
P 		3567.6
(1.2)
P 		269
avr 3344.9
(-3) 		3392.7
(-2.6) 		3997.3
(3) 		3567.8
(-1) 		3444.5
(-2.1) 		3558
(-1) 		652
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1570
1 2 3 4 range
A 1354.7
(1.4)
P 		1288.4
(1.1)
P 		1697
(3)
P 		420.7
(-3)
P 		1276
B 1182.5
(-0.2)
P 		1524.4
(2.4)
P 		1611
(3)
P 		805.8
(-3)
P 		805
C 1227.6
(-0.1)
P 		1352
(0.4)
P 		1991
(3)
P 		533.4
(-3)
P 		1458
avr 1254.9
(0.4) 		1388.3
(1.1) 		1766.3
(3) 		586.6
(-3) 		1180

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 710
1 2 3 4 5 6 range
A 633.1
(-3)
P 		1167
(3)
P 		809.3
(-1)
P 		863.9
(-0.4)
P 		1083.9
(2.1)
P 		860.9
(-0.4)
P 		534
B 1120.2
(-0.9)
P 		1127
(-0.8)
P 		1123.3
(-0.9)
P 		1003.9
(-3)
P 		1342.7
(3)
P 		1331.3
(2.8)
P 		339
C 1253.2
(3)
P 		1071.3
(1)
P 		928.9
(-0.6)
P 		705.2
(-3)
P 		1112.1
(1.5)
P 		1194.3
(2.4)
P 		548
avr 1002.2
(-0.3) 		1121.8
(1.9) 		953.8
(-1.2) 		857.7
(-3) 		1179.6
(3) 		1128.8
(2.1) 		322
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190251_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12009
Sequence Type Exemplar sequence
Representative Public ID CD4.6 NCBI
Target Description CD4.6 /REP_DB=WormBase Gene ID /WP=CE16954 /GEN=pas-6 /TR=SW:O44156 /GB=AAB88344.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=protease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072071(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072071 NCBI Caenorhabditis elegans CD4.6 (protease) mRNA, complete cds. 11/11 None
SNAP00000006227 ENSEMBL cdna:SNAP chromosome:CEL140:V:5585953:5586929:-1 11/11 None
GENEFINDER00000006243 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:5585953:5586929:-1 11/11 None
CD4.6.2 ENSEMBL cdna:known chromosome:CEL140:V:5585364:5586943:-1 gene:CD4.6 11/11 None
CD4.6.1 ENSEMBL cdna:known chromosome:CEL140:V:5585810:5586943:-1 gene:CD4.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:5585952-5586929(-) 100.0 100.0
Public Domain and Genome References
Gene Title protease
Gene Symbol pas-6
Ensembl CD4.6
Entrez Gene 178943 Entrez gene
SwissProt O44156 EMBL-EBI
WormBase CE16954 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:249161_AT 20S proteasome alpha subunit F1 (PAF1) at
CANINE:1592695_AT similar to Proteasome subunit alpha type 1 (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30) cfa
CANINE:1586313_AT similar to Proteasome subunit alpha type 1 (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30) cfa
CANINE_2:CFA.11083.1.A1_S_AT similar to Proteasome subunit alpha type 1 (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30) cfa
CANINE_2:CFA.19196.1.S1_X_AT similar to Proteasome subunit alpha type 1 (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30) cfa
CANINE_2:CFA.19196.2.S1_AT similar to Proteasome subunit alpha type 1 (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30) cfa
CANINE_2:CFAAFFX.12323.1.S1_AT similar to Proteasome subunit alpha type 1 (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30) cfa
CANINE_2:CFAAFFX.17342.1.S1_AT similar to Proteasome subunit alpha type 1 (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30) cfa
CANINE_2:CFAAFFX.30689.1.S1_X_AT similar to Proteasome subunit alpha type 1 (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30) cfa
DROSOPHILA_2:1631376_AT Proteasome 35kD subunit dm
DROSGENOME1:143314_AT Proteasome 35kD subunit dm
CHICKEN:GGA.3661.1.S1_A_AT proteasome (prosome, macropain) subunit, alpha type, 1 gga
HG-U133_PLUS_2:210759_S_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U133A:210759_S_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-FOCUS:210759_S_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U133A_2:210759_S_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U133_PLUS_2:201676_X_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U133A_2:201676_X_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U133A:201676_X_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U133_PLUS_2:211746_X_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U133A:211746_X_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U133A_2:211746_X_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HU35KSUBD:RC_H23538_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HUGENEFL:M64992_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
U133_X3P:G190446_3P_S_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U95AV2:38371_AT proteasome (prosome, macropain) subunit, alpha type, 1 hs
HG-U95D:73114_AT Proteasome (prosome, macropain) subunit, alpha type, 1 hs
HU35KSUBD:RC_N70998_AT Proteasome (prosome, macropain) subunit, alpha type, 1 hs
MOE430A:1415695_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOUSE430_2:1415695_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOE430B:1415695_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOUSE430A_2:1415695_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MG-U74AV2:96892_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOE430A:1436770_X_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOUSE430A_2:1436770_X_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOUSE430_2:1436770_X_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOE430A:1436769_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOUSE430A_2:1436769_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOUSE430_2:1436769_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOE430B:1458292_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MOUSE430_2:1458292_AT proteasome (prosome, macropain) subunit, alpha type 1 mm
MU19KSUBA:TC15682_AT Proteasome (prosome, macropain) subunit, alpha type 1, mRNA (cDNA clone MGC:6546 IMAGE:2655483) mm
MU19KSUBC:TC36011_AT Proteasome (prosome, macropain) subunit, alpha type 1, mRNA (cDNA clone MGC:6546 IMAGE:2655483) mm
RG-U34A:D90265_S_AT proteasome (prosome, macropain) subunit, alpha type 1 rn
RAE230A:1398778_AT proteasome (prosome, macropain) subunit, alpha type 1 rn
RAT230_2:1398778_AT proteasome (prosome, macropain) subunit, alpha type 1 rn
RG-U34A:RC_AI009111_AT proteasome (prosome, macropain) subunit, alpha type 1 rn
YEAST_2:1778905_AT 20S proteasome alpha-type subunit Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6511 ubiquitin-dependent protein catabolism inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5839 proteasome core complex (sensu Eukaryota) inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4175 endopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_504472 CD4.6 [Caenorhabditis elegans] gb|AAB88344.1| Proteasome alpha subunit protein 6 [Caenorhabditis elegans] sp|O44156|PSA1_CAEEL Proteasome subunit alpha type 1 (Proteasome subunit alpha 6) 1.0E-138
blast CAE64609 Hypothetical protein CBG09365 [Caenorhabditis briggsae] 1.0E-128
Protein Domains
Database ID Description E-Value
Pfam IPR001353 EMBL-EBI Peptidase T1, 20S proteasome 6.2E-59
Sequence
Target Sequence 
>C. ELEGANS:190251_S_AT
tgacactcacgctggagtttccatcgctggtctcctctccgatggtcgcatcttggctcg
ctacctccaaaccgagtgctcgagttggcgttgggattacaagcaagcggttccaatcaa
gaagctcgctgaatctatgcaattgaaacttcaagccaatacacaatattatggccgtcg
tccattcggagttggaattctgattgccggatatgacaaagatggagcacacatcattca
aactgacccatctgctgaagtcgtcagcatgcatggaacttcaatcggagcaagatctca
gtctgcgcgcacttacctcgagagaaatgttgataacttcgagaaatcaactccggaaca
attgattgtccatgctctccttgctcttcgcgacacacttccagccgaagaaaacctcaa
cgctcagaatacgtctattggaattgtcgggaaagattctccattcagtcttctcgaaga
tgctcaagtcgccgttcatctcaaccaagtttccacac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGACACTCACGCTGGAGTTTCCATC 243 571 210 Antisense
AACCGAGTGCTCGAGTTGGCGTTGG 684 141 279 Antisense
GAAGCTCGCTGAATCTATGCAATTG 701 341 330 Antisense
ATATTATGGCCGTCGTCCATTCGGA 183 19 375 Antisense
GAGCACACATCATTCAAACTGACCC 25 391 434 Antisense
AACTGACCCATCTGCTGAAGTCGTC 216 143 450 Antisense
CGGAGCAAGATCTCAGTCTGCGCGC 581 243 495 Antisense
AACAATTGATTGTCCATGCTCTCCT 236 135 566 Antisense
AAAGATTCTCCATTCAGTCTTCTCG 328 123 661 Antisense
AAGATGCTCAAGTCGCCGTTCATCT 39 155 686 Antisense
GTTCATCTCAACCAAGTTTCCACAC 144 445 703 Antisense
Sequence Source Affymetrix Proprietary Database