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[190244_s_at] zinc carboxypeptidase

Description F01D4.4 /REP_DB=WormBase Gene ID /WP=CE09156 /TR=O17754 /GB=CAB02881.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=zinc carboxypeptidase
Cluster 6grp_highest_10_10 > 22      6grp_high1_10_10 > 03      4grp_highest_8_8 > 54      4grp_high_8_8 > 10      6grp_highest_nonorm > 16      6grp_total > 24      4grp_total > 22      6grp_highest_sub > De      6grp_cgc > 31      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 7651
1 2 3 4 range
A 11464.8
(3)
P
5834.3
(-2)
P
4760
(-3)
P
11189.2
(2.8)
P
6705
B 10461.7
(2.3)
P
6597.5
(-1.2)
P
4649.3
(-3)
P
11263.1
(3)
P
6614
C 10736.1
(1.9)
P
5702.1
(-2.1)
P
4492.9
(-3)
P
12144
(3)
P
7651
avr 10887.5
(2.4)
6044.6
(-1.8)
4634.1
(-3)
11532.1
(3)
6898

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 4158
1 2 3 4 5 6 range
A 8396.1
(3)
P
8320.3
(2.9)
P
7294
(0.9)
P
6893.4
(0.1)
P
5310.6
(-3)
P
6270.7
(-1.1)
P
3086
B 9279.5
(3)
P
8594.9
(2)
P
8997.6
(2.6)
P
6851.3
(-0.5)
P
5427.6
(-2.6)
P
5121.9
(-3)
P
4158
C 8792.8
(3)
P
8288.5
(2.1)
P
8042.6
(1.7)
P
5857.5
(-2.3)
P
6980.4
(-0.3)
P
5455.7
(-3)
P
3337
avr 8822.8
(3)
8401.2
(2.2)
8111.4
(1.7)
6534.1
(-1.3)
5906.2
(-2.5)
5616.1
(-3)
3207
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3097
1 2 3 4 range
A 4174.3
(3)
P
1266.5
(-3)
P
1244.3
(-3)
P
1637.9
(-2.2)
P
2930
B 3336.1
(3)
P
1629.4
(-1.5)
P
1077.3
(-3)
P
2400.2
(0.5)
P
2259
C 3553.9
(3)
P
1639.4
(-2.8)
P
1565.9
(-3)
P
2047.7
(-1.5)
P
1988
avr 3688.1
(3)
1511.8
(-2.5)
1295.8
(-3)
2028.6
(-1.2)
2392

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2081
1 2 3 4 5 6 range
A 1547.7
(-2.9)
P
2959.1
(3)
P
1588.5
(-2.7)
P
1748.3
(-2.1)
P
1602.5
(-2.7)
P
1526.7
(-3)
P
1432
B 3228.8
(3)
P
2860.9
(1.4)
P
2184.9
(-1.4)
P
1814.7
(-3)
P
2205.2
(-1.3)
P
1909.9
(-2.6)
P
1414
C 3259.1
(3)
P
2529.1
(0.9)
P
2047
(-0.5)
P
1177.9
(-3)
P
2258.7
(0.1)
P
1826.3
(-1.1)
P
2081
avr 2678.5
(2.5)
2783
(3)
1940.1
(-1.2)
1580.3
(-3)
2022.1
(-0.8)
1754.3
(-2.1)
1203
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190244_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8655
Sequence Type Exemplar sequence
Representative Public ID F01D4.4 NCBI
Target Description F01D4.4 /REP_DB=WormBase Gene ID /WP=CE09156 /TR=O17754 /GB=CAB02881.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=zinc carboxypeptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069534(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_069534 NCBI Caenorhabditis elegans EGg Laying defective family member (egl-21) (egl-21) mRNA, complete cds. 11/11 None
SNAP00000032307 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10478614:10481727:-1 11/11 None
GENEFINDER00000032310 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10478614:10481727:-1 11/11 None
F01D4.4.1 ENSEMBL cdna:known chromosome:CEL140:IV:10478176:10481816:-1 gene:F01D4.4 11/11 None
F01D4.4.3 ENSEMBL cdna:known chromosome:CEL140:IV:10478176:10481946:-1 gene:F01D4.4 11/11 None
F01D4.4.6 ENSEMBL cdna:known chromosome:CEL140:IV:10478423:10481746:-1 gene:F01D4.4 11/11 None
F01D4.4.2 ENSEMBL cdna:known chromosome:CEL140:IV:10478423:10481818:-1 gene:F01D4.4 11/11 None
F01D4.4.5 ENSEMBL cdna:known chromosome:CEL140:IV:10478440:10481778:-1 gene:F01D4.4 11/11 None
F01D4.4.4 ENSEMBL cdna:known chromosome:CEL140:IV:10478459:10481778:-1 gene:F01D4.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10478619-10481745(-) 100.0 100.0
Public Domain and Genome References
Gene Title zinc carboxypeptidase
Gene Symbol egl-21
Ensembl F01D4.4
Entrez Gene 177940 Entrez gene
SwissProt O17754 EMBL-EBI
WormBase CE09156 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1588916_AT similar to Carboxypeptidase E precursor (CPH) (Carboxypeptidase H) (CPE) (Enkephalin convertase) (Prohormone processing carboxypeptidase) cfa
CANINE:1583244_AT similar to Carboxypeptidase E precursor (CPH) (Carboxypeptidase H) (CPE) (Enkephalin convertase) (Prohormone processing carboxypeptidase) cfa
CANINE_2:CFA.1374.1.S1_AT similar to Carboxypeptidase E precursor (CPH) (Carboxypeptidase H) (CPE) (Enkephalin convertase) (Prohormone processing carboxypeptidase) cfa
CANINE_2:CFAAFFX.13996.1.S1_S_AT similar to Carboxypeptidase E precursor (CPH) (Carboxypeptidase H) (CPE) (Enkephalin convertase) (Prohormone processing carboxypeptidase) cfa
CHICKEN:GGA.5494.1.S1_AT carboxypeptidase E gga
HG-U133_PLUS_2:201116_S_AT carboxypeptidase E hs
HG-U133A_2:201116_S_AT carboxypeptidase E hs
HG-U133A:201116_S_AT carboxypeptidase E hs
HG-U133_PLUS_2:201117_S_AT carboxypeptidase E hs
HG-U133A_2:201117_S_AT carboxypeptidase E hs
HG-U133A:201117_S_AT carboxypeptidase E hs
HG-FOCUS:201117_S_AT carboxypeptidase E hs
HU35KSUBD:RC_T94885_S_AT carboxypeptidase E hs
HUGENEFL:X51405_AT carboxypeptidase E hs
U133_X3P:G4503008_3P_X_AT carboxypeptidase E hs
U133_X3P:G4503008_3P_A_AT carboxypeptidase E hs
U133_X3P:HS.75360.0.A1_3P_A_AT carboxypeptidase E hs
HG-U95AV2:36606_AT carboxypeptidase E hs
MOE430A:1439437_X_AT carboxypeptidase E mm
MOUSE430_2:1439437_X_AT carboxypeptidase E mm
MOUSE430A_2:1439437_X_AT carboxypeptidase E mm
MOE430A:1415949_AT carboxypeptidase E mm
MOUSE430A_2:1415949_AT carboxypeptidase E mm
MOUSE430_2:1415949_AT carboxypeptidase E mm
MU11KSUBA:U23184_S_AT carboxypeptidase E mm
MU11KSUBB:MSA.13505.0_S_AT carboxypeptidase E mm
MU11KSUBB:X61232_S_AT carboxypeptidase E mm
MG-U74AV2:99642_I_AT carboxypeptidase E mm
MG-U74AV2:99643_F_AT carboxypeptidase E mm
MG-U74CV2:137173_AT carboxypeptidase E mm
MG-U74CV2:170012_R_AT carboxypeptidase E mm
MU19KSUBC:TC40890_AT Carboxypeptidase E, mRNA (cDNA clone MGC:7101 IMAGE:3157558) mm
MU19KSUBC:TC40890_G_AT Carboxypeptidase E, mRNA (cDNA clone MGC:7101 IMAGE:3157558) mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4181 metallocarboxypeptidase activity inferred from electronic annotation QuickGO AmiGO
4182 carboxypeptidase A activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02881 Hypothetical protein F01D4.4 [Caenorhabditis elegans] ref|NP_501935.1| EGg Laying defective family member (egl-21) [Caenorhabditis elegans] 0.0
blast CAE63795 Hypothetical protein CBG08337 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 5.2E-51
Pfam IPR008575 EMBL-EBI Peptidase M14B 1.1E-65
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 5.2E-51
Pfam IPR008575 EMBL-EBI Peptidase M14B 1.1E-65
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501935.1 1 7-29
F01D4.4.1 1 7-29
F01D4.4.3 1 7-29
F01D4.4.6 1 7-29
F01D4.4.2 1 7-29
F01D4.4.5 1 7-29
F01D4.4.4 1 7-29
Sequence
Target Sequence
>C. ELEGANS:190244_S_AT
gctcgctaagtcctatgctgataatcatgctcatatgtcaaagaacgatcatgccccgtg
tgacggaaccagccaagatgcttttgctcgccaaggaggaattaccaacggagctaagtg
gtactcggttgccggaggaatgcaagacttcaactacttggctaccaatgcaatggaaat
tacattggaattgagctgtgagaagatgccagaaggatctcaacttcctcgattctggga
ggacaaccagaaatccattttcgagtatgtttggaaatctcacagcggagttaagggaat
ggttgtcgatgcaatgaccggcgagccaatcaagcgggccgttgtctggattcgtaatgg
aactgagactgttccagttaagcatccagttaccacatggtccgagggagacttctacag
agtgctcccagctggaaagtacgaaattatcgttgccgctgaaggatacgatattgccgc
caagaatgtgacagtcgagaacaaggtccgcgacagcgctcttgttgtcaactttgc


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
GCTCGCTAAGTCCTATGCTGATAAT 235 299 810 Antisense
CAAAGAACGATCATGCCCCGTGTGA 145 193 848 Antisense
AACCAGCCAAGATGCTTTTGCTCGC 158 149 876 Antisense
GAGCTAAGTGGTACTCGGTTGCCGG 690 387 920 Antisense
AAGACTTCAACTACTTGGCTACCAA 522 153 953 Antisense
GAAGGATCTCAACTTCCTCGATTCT 3 335 1021 Antisense
GAGCCAATCAAGCGGGCCGTTGTCT 516 383 1132 Antisense
GGCCGTTGTCTGGATTCGTAATGGA 324 543 1146 Antisense
AAGCATCCAGTTACCACATGGTCCG 435 151 1189 Antisense
GGAGACTTCTACAGAGTGCTCCCAG 149 519 1216 Antisense
ACAGCGCTCTTGTTGTCAACTTTGC 579 109 1322 Antisense
Sequence Source Affymetrix Proprietary Database