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[190238_at] carbonic anhydrase I

Description F54D8.4 /REP_DB=WormBase Gene ID /WP=CE01310 /TR=Q20781 /GB=AAA20616.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=carbonic anhydrase I
Cluster 6grp_highest_10_10 > 55      6grp_high1_10_10 > 44      4grp_highest_8_8 > 62      4grp_high_8_8 > 18      6grp_highest_nonorm > 81      6grp_total > 0      4grp_total > 29      6grp_total_sub > Hat      6grp_cgc > 65      6grp_high1_sub > 02      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 201
1 2 3 4 range
A 249.8
(3)
P 		133.5
(-1.4)
P 		92.3
(-3)
P 		248.3
(2.9)
P 		158
B 268.8
(3)
P 		209.4
(1.1)
P 		84.7
(-3)
P 		171.5
(-0.2)
P 		184
C 281.1
(2.8)
P 		213.6
(0.4)
P 		117.7
(-3)
P 		285.9
(3)
P 		168
avr 266.6
(3) 		185.5
(0.1) 		98.2
(-3) 		235.2
(1.9) 		168

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 174
1 2 3 4 5 6 range
A 199.5
(-3)
P 		304.9
(2.4)
P 		315.9
(3)
P 		282.8
(1.3)
P 		269.3
(0.6)
P 		240.6
(-0.9)
P 		116
B 280.5
(-0.7)
P 		350.5
(2.1)
P 		222
(-3)
P 		322.1
(1)
P 		245.2
(-2.1)
P 		373.6
(3)
P 		152
C 231.3
(-2.3)
P 		318.5
(1.6)
P 		257
(-1.2)
P 		349.4
(3)
P 		216.1
(-3)
P 		292.7
(0.4)
P 		133
avr 237.1
(-3) 		324.6
(3) 		265
(-1.1) 		318.1
(2.6) 		243.5
(-2.6) 		302.3
(1.5) 		88
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 73
1 2 3 4 range
A 90.9
(3)
P 		29
(-2.6)
P 		24.1
(-3)
P 		36.3
(-1.9)
P 		67
B 85.7
(3)
P 		51.7
(-0.1)
P 		19.6
(-3)
P 		36.5
(-1.5)
P 		66
C 93
(3)
P 		61.4
(-0.6)
P 		41
(-3)
P 		48.2
(-2.2)
P 		52
avr 89.9
(3) 		47.4
(-1.1) 		28.2
(-3) 		40.3
(-1.8) 		62

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 103
1 2 3 4 5 6 range
A 36.8
(-3)
P 		108.4
(3)
P 		68.8
(-0.3)
P 		71.7
(-0.1)
P 		81.3
(0.7)
P 		58.6
(-1.2)
P 		72
B 97.6
(0.1)
P 		116.7
(1.4)
P 		53.9
(-3)
P 		85.3
(-0.8)
P 		99.6
(0.2)
P 		139.3
(3)
P 		85
C 85.7
(0.7)
P 		97.2
(2.9)
P 		65.4
(-3)
P 		70.3
(-2.1)
P 		69.9
(-2.2)
P 		98
(3)
P 		33
avr 73.4
(-1.6) 		107.4
(3) 		62.7
(-3) 		75.8
(-1.2) 		83.6
(-0.2) 		98.6
(1.8) 		45
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190238_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7860
Sequence Type Exemplar sequence
Representative Public ID F54D8.4 NCBI
Target Description F54D8.4 /REP_DB=WormBase Gene ID /WP=CE01310 /TR=Q20781 /GB=AAA20616.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=carbonic anhydrase I
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065682(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065682 NCBI Caenorhabditis elegans Carbonic AnHydrase family member (cah-1) (cah-1) mRNA, complete cds. 11/11 None
SNAP00000022622 ENSEMBL cdna:SNAP chromosome:CEL140:III:5083023:5085248:-1 10/11 None
GENEFINDER00000022636 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:5083023:5085248:-1 10/11 None
F54D8.4 ENSEMBL cdna:known chromosome:CEL140:III:5083165:5085248:-1 gene:F54D8.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:5083163-5085247(-) 90.8 100.0
Public Domain and Genome References
Gene Title carbonic anhydrase I
Gene Symbol cah-1
Ensembl F54D8.4
Entrez Gene 186231 Entrez gene
SwissProt Q20781 EMBL-EBI
WormBase CE01310 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1591127_AT similar to Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) cfa
CANINE_2:CFA.9271.1.A1_AT similar to Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) cfa
CANINE_2:CFAAFFX.26508.1.S1_AT similar to Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) cfa
DROSOPHILA_2:1641185_AT dm
DROSGENOME1:144656_AT dm
CHICKEN:GGAAFFX.25710.1.S1_AT similar to Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) (Cerebral protein-15) (hucep-15) (UNQ533/PRO1076) gga
HG-U133_PLUS_2:220889_S_AT carbonic anhydrase X hs
HG-U133A:220889_S_AT carbonic anhydrase X hs
HG-FOCUS:220889_S_AT carbonic anhydrase X hs
HG-U133A_2:220889_S_AT carbonic anhydrase X hs
HG-U133_PLUS_2:223550_S_AT carbonic anhydrase X hs
HG-U133B:223550_S_AT carbonic anhydrase X hs
HU35KSUBA:RC_AA609023_AT carbonic anhydrase X hs
HU35KSUBD:RC_N26826_AT carbonic anhydrase X hs
HU35KSUBD:RC_H23162_S_AT carbonic anhydrase X hs
U133_X3P:G9910365_3P_S_AT carbonic anhydrase X hs
U133_X3P:G13094698_3P_A_AT carbonic anhydrase X hs
HG-U95B:46593_AT carbonic anhydrase X hs
HG-U95B:50694_AT carbonic anhydrase X hs
MOUSE430_2:1431288_AT carbonic anhydrase 10 mm
MOE430B:1431288_AT carbonic anhydrase 10 mm
MG-U74BV2:107346_AT carbonic anhydrase 10 mm
MG-U74CV2:166211_AT carbonic anhydrase 10 mm
MOE430A:1424547_AT carbonic anhydrase 10 mm
MOUSE430A_2:1424547_AT carbonic anhydrase 10 mm
MOUSE430_2:1424547_AT carbonic anhydrase 10 mm
MOE430B:1445497_AT Car10 mRNA for carbonic anhydrase-related protein X mm
MOUSE430_2:1445497_AT Car10 mRNA for carbonic anhydrase-related protein X mm
MG-U74CV2:167747_F_AT Car10 mRNA for carbonic anhydrase-related protein X mm
RG-U34C:RC_AI101117_AT similar to Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) rn
RAE230A:1376726_AT similar to Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) rn
RAT230_2:1376726_AT similar to Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) rn
RAE230B:1396778_AT Similar to Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) rn
RAT230_2:1396778_AT Similar to Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6730 one-carbon compound metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4089 carbonate dehydratase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA20616 Carbonic anhydrase protein 1 [Caenorhabditis elegans] ref|NP_498083.1| Carbonic AnHydrase family member (cah-1) [Caenorhabditis elegans] sp|Q20781|CAH1_CAEEL Putative carbonic anhydrase-like protein 1 precursor 0.0
blast CAE75085 Hypothetical protein CBG23005 [Caenorhabditis briggsae] 1.0E-144
blast CAE75085 Hypothetical protein CBG23005 [Caenorhabditis briggsae] 1.0E-137
blast CAE75085 Hypothetical protein CBG23005 [Caenorhabditis briggsae] 1.0E-113
blast AAA20616 Carbonic anhydrase protein 1 [Caenorhabditis elegans] ref|NP_498083.1| Carbonic AnHydrase family member (cah-1) [Caenorhabditis elegans] sp|Q20781|CAH1_CAEEL Putative carbonic anhydrase-like protein 1 precursor 5.0E-99
blast AAA20616 Carbonic anhydrase protein 1 [Caenorhabditis elegans] ref|NP_498083.1| Carbonic AnHydrase family member (cah-1) [Caenorhabditis elegans] sp|Q20781|CAH1_CAEEL Putative carbonic anhydrase-like protein 1 precursor 3.0E-95
blast NP_495567 Carbonic AnHydrase family member (cah-2) [Caenorhabditis elegans] gb|AAB93341.3| Carbonic anhydrase protein 2 [Caenorhabditis elegans] sp|Q18932|CAH2_CAEEL Putative carbonic anhydrase-like protein 2 precursor 3.0E-56
blast NP_495567 Carbonic AnHydrase family member (cah-2) [Caenorhabditis elegans] gb|AAB93341.3| Carbonic anhydrase protein 2 [Caenorhabditis elegans] sp|Q18932|CAH2_CAEEL Putative carbonic anhydrase-like protein 2 precursor 7.0E-53
Protein Domains
Database ID Description E-Value
Pfam IPR001148 EMBL-EBI Carbonic anhydrase, eukaryotic 2.7E-43
Pfam IPR001148 EMBL-EBI Carbonic anhydrase, eukaryotic 3.1E-39
Pfam IPR001148 EMBL-EBI Carbonic anhydrase, eukaryotic 3.0E-41
Sequence
Target Sequence 
>C. ELEGANS:190238_AT
tattcctctaaaaaaccatccgtcaatattacaagtggtccattatacggttataggtat
cgggttcaacgaatcgattttcatatgggtcgtaaaaatgagaacggaagtgagcataca
ataaatggacgacgatttccgatggaagtacaattagttgcatataatacagatttgtat
ccaaattttacgagcgcctccaagtctccacatggaattgcaattttatcagttttggta
gattttggacctgaaactaatcaagaactcatcaaactaacaattgcaacagctagcatc
agttacaaggatcaacgtgtccaacttgctgatttcgaaccttggcgacttcttccattc
actagagatattatcacttatgaaggatctctcacttctcctggatgccatgagactgtc
acttggattattctgaatcaacctatttttatcaaaaaggagcatttcgaggagtggtca
cacttatatctgagcatggaaggcgccgagaaagtcccc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TATTCCTCTAAAAAACCATCCGTCA 94 665 502 Antisense
GTATCCAAATTTTACGAGCGCCTCC 31 453 678 Antisense
GCCTCCAAGTCTCCACATGGAATTG 97 283 697 Antisense
AGGATCAACGTGTCCAACTTGCTGA 16 57 809 Antisense
GCTGATTTCGAACCTTGGCGACTTC 545 293 829 Antisense
CGACTTCTTCCATTCACTAGAGATA 697 251 847 Antisense
TATGAAGGATCTCTCACTTCTCCTG 105 657 880 Antisense
TCTCACTTCTCCTGGATGCCATGAG 530 613 891 Antisense
GGATGCCATGAGACTGTCACTTGGA 371 511 904 Antisense
GAGTGGTCACACTTATATCTGAGCA 511 401 973 Antisense
CATGGAAGGCGCCGAGAAAGTCCCC 356 209 996 Antisense
Sequence Source Affymetrix Proprietary Database