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[190223_at] Src homology domain 2

Description K11E4.2 /REP_DB=WormBase Gene ID /WP=CE06180 /TR=Q21429 /GB=CAA94158.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=Src homology domain 2
Cluster 6grp_high1_10_10 > 61      6grp_total > 72      4grp_total > 55      6grp_high1_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 167
1 2 3 4 range
A 324.6
(3)
P 		214.6
(-2.5)
P 		227.2
(-1.9)
P 		204.4
(-3)
A 		120
B 327.8
(3)
P 		202.9
(-1.7)
A 		242.7
(-0.2)
P 		169
(-3)
A 		159
C 335.9
(3)
P 		201.4
(-2.5)
A 		242.6
(-0.8)
P 		189.9
(-3)
A 		146
avr 329.4
(3) 		206.3
(-2.2) 		237.5
(-0.9) 		187.8
(-3) 		142

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 281
1 2 3 4 5 6 range
A 245.5
(-0.9)
P 		313.9
(0.6)
P 		426.1
(3)
P 		381.2
(2)
P 		314.8
(0.6)
P 		145.4
(-3)
P 		281
B 219.3
(-2.4)
P 		301.6
(1)
P 		351.2
(3)
P 		307.9
(1.2)
P 		337.8
(2.5)
P 		204
(-3)
P 		147
C 173.1
(-3)
M 		293.9
(0)
P 		350.6
(1.4)
P 		413.9
(3)
P 		268.8
(-0.6)
P 		186.7
(-2.7)
P 		241
avr 212.6
(-2) 		303.1
(0.8) 		376
(3) 		367.7
(2.7) 		307.1
(0.9) 		178.7
(-3) 		197
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 88
1 2 3 4 range
A 118.2
(3)
P 		46.6
(-1.9)
P 		59.4
(-1)
P 		29.9
(-3)
A 		88
B 104.5
(3)
P 		50.1
(-1.8)
A 		56.2
(-1.2)
P 		36
(-3)
A 		69
C 111.2
(3)
P 		57.9
(-1)
A 		84.6
(1)
P 		32
(-3)
A 		79
avr 111.3
(3) 		51.5
(-1.6) 		66.7
(-0.4) 		32.6
(-3) 		79

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 102
1 2 3 4 5 6 range
A 45.3
(-2.2)
P 		111.6
(3)
P 		92.8
(1.5)
P 		96.7
(1.8)
P 		95
(1.7)
P 		35.4
(-3)
P 		76
B 76.3
(-3)
P 		100.4
(-0.6)
P 		85.3
(-2.1)
P 		81.5
(-2.5)
P 		137.2
(3)
P 		76.1
(-3)
P 		61
C 64.1
(-2.6)
M 		89.7
(3)
P 		89.2
(2.9)
P 		83.2
(1.6)
P 		87
(2.4)
P 		62.5
(-3)
P 		27
avr 61.9
(-2.5) 		100.6
(2.3) 		89.1
(0.9) 		87.1
(0.6) 		106.4
(3) 		58
(-3) 		48
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190223_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17833
Sequence Type Exemplar sequence
Representative Public ID K11E4.2 NCBI
Target Description K11E4.2 /REP_DB=WormBase Gene ID /WP=CE06180 /TR=Q21429 /GB=CAA94158.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=Src homology domain 2
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077894(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077894 NCBI Caenorhabditis elegans K11E4.2 (K11E4.2) mRNA, complete cds. 11/11 None
SNAP00000028495 ENSEMBL cdna:SNAP chromosome:CEL140:X:13717559:13719065:1 11/11 None
GENEFINDER00000028501 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:13717559:13719065:1 11/11 None
K11E4.2 ENSEMBL cdna:known chromosome:CEL140:X:13717559:13719065:1 gene:K11E4.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:13717558-13719065(+) 100.0 100.0
Public Domain and Genome References
Gene Title Src homology domain 2
Ensembl K11E4.2
Entrez Gene 187296 Entrez gene
SwissProt Q21429 EMBL-EBI
WormBase CE34056 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA94158 Hypothetical protein K11E4.2 [Caenorhabditis elegans] ref|NP_510295.2| K11E4.2 [Caenorhabditis elegans] 1.0E-158
blast CAA94158 Hypothetical protein K11E4.2 [Caenorhabditis elegans] ref|NP_510295.2| K11E4.2 [Caenorhabditis elegans] 1.0E-123
blast CAE63092 Hypothetical protein CBG07382 [Caenorhabditis briggsae] 4.0E-51
blast CAE63092 Hypothetical protein CBG07382 [Caenorhabditis briggsae] 8.0E-47
Protein Domains
Database ID Description E-Value
Pfam IPR000980 EMBL-EBI SH2 motif 7.5E-5
Pfam IPR000980 EMBL-EBI SH2 motif 7.5E-5
Sequence
Target Sequence 
>C. ELEGANS:190223_AT
gctgttaaggttgtcggtccgtatgttagtgtatatcagttggacttatttcttaacatc
agcagtttcactataacatgttttcacattcaagacggcagaactcatttgctcggaaga
tataagaataaccagatctcgcactataaatacagggaaatagatggacgtcattatttg
ggcattgtgatgaaaattggaagaactgagaaacgagagtgcaacgttttcatgttggat
aacgacatcgccctgaatgaccttacaacaaaattgcgaagtgtcgatgaacgaagacat
aataatgcgctacagttggaaactcgcctgaggtcgacacaagaatacaggtacacaccg
aacatgcttgcatgctaccatggtccgctgtcacacgaagacgcctgtaggcaactagtt
ctaccgggagaattcatcataagggatagttcaatgcgtggagagtttgccgtttcctat
aaaactagtcatggacctcacgacaaatcaattgtgcccaacaataacatcgactttt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTGTTAAGGTTGTCGGTCCGTATG 440 257 94 Antisense
GACGGCAGAACTCATTTGCTCGGAA 465 375 187 Antisense
TAACCAGATCTCGCACTATAAATAC 582 635 222 Antisense
GTTGGATAACGACATCGCCCTGAAT 454 435 327 Antisense
ATCGCCCTGAATGACCTTACAACAA 637 35 340 Antisense
TGGAAACTCGCCTGAGGTCGACACA 255 547 410 Antisense
GTACACACCGAACATGCTTGCATGC 520 459 444 Antisense
GTCACACGAAGACGCCTGTAGGCAA 316 465 483 Antisense
TGCGTGGAGAGTTTGCCGTTTCCTA 519 575 548 Antisense
AAACTAGTCATGGACCTCACGACAA 619 127 575 Antisense
GTGCCCAACAATAACATCGACTTTT 705 477 607 Antisense
Sequence Source Affymetrix Proprietary Database