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[190222_s_at] adenosine A1 receptor

Description T21B4.4 /REP_DB=WormBase Gene ID /WP=CE26004 /TR=O18099 /GB=CAB03371.2 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=adenosine A1 receptor
Cluster 6grp_total > 03      4grp_total > 04      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 432
1 2 3 4 range
A 182.9
(-1.8)
A 		133.1
(-2.8)
A 		123.5
(-3)
A 		427.7
(3)
A 		304
B 208.3
(0.1)
A 		125.5
(-1.6)
A 		56.7
(-3)
A 		348.8
(3)
A 		292
C 187.5
(-1)
A 		45.8
(-3)
A 		85.5
(-2.4)
A 		477.9
(3)
A 		432
avr 192.9
(-1.1) 		101.5
(-2.8) 		88.6
(-3) 		418.1
(3) 		330

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 168
1 2 3 4 5 6 range
A 153.9
(1.2)
A 		121.1
(-0.9)
A 		143.8
(0.6)
A 		181.8
(3)
A 		87.7
(-3)
A 		98.4
(-2.3)
A 		94
B 143
(0.9)
A 		178.8
(3)
A 		78.9
(-2.9)
A 		106.6
(-1.2)
A 		103.9
(-1.4)
A 		76.4
(-3)
A 		102
C 112.9
(0.9)
A 		165.6
(3)
A 		152.9
(2.5)
A 		153.6
(2.5)
A 		119.8
(1.2)
A 		14.1
(-3)
A 		152
avr 136.6
(1.8) 		155.2
(3) 		125.2
(1) 		147.3
(2.5) 		103.8
(-0.3) 		63
(-3) 		92
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 68
1 2 3 4 range
A 66.6
(3)
A 		28.9
(-3)
A 		32.3
(-2.5)
A 		62.6
(2.4)
A 		38
B 66.4
(2.2)
A 		31
(-1.2)
A 		13.1
(-3)
A 		74.3
(3)
A 		61
C 62.1
(1.4)
A 		13.2
(-3)
A 		29.8
(-1.5)
A 		80.6
(3)
A 		67
avr 65
(2.1) 		24.4
(-3) 		25.1
(-2.9) 		72.5
(3) 		48

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 55
1 2 3 4 5 6 range
A 28.4
(-1.8)
A 		43.1
(2.2)
A 		31.3
(-1)
A 		46.1
(3)
A 		26.5
(-2.3)
A 		24
(-3)
A 		22
B 49.7
(1.5)
A 		59.5
(3)
A 		19.2
(-3)
A 		28.2
(-1.7)
A 		42.2
(0.4)
A 		28.5
(-1.6)
A 		40
C 41.9
(1.9)
A 		50.5
(3)
A 		38.9
(1.5)
A 		30.9
(0.4)
A 		38.8
(1.5)
A 		4.7
(-3)
A 		46
avr 40
(0.9) 		51
(3) 		29.8
(-1) 		35.1
(0) 		35.8
(0.1) 		19.1
(-3) 		32
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190222_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3908
Sequence Type Exemplar sequence
Representative Public ID T21B4.4 NCBI
Target Description T21B4.4 /REP_DB=WormBase Gene ID /WP=CE26004 /TR=O18099 /GB=CAB03371.2 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=adenosine A1 receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064266(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064266 NCBI Caenorhabditis elegans T21B4.4 (T21B4.4) mRNA, complete cds. 11/11 None
SNAP00000006686 ENSEMBL cdna:SNAP chromosome:CEL140:II:12497304:12499607:-1 10/11 None
GENEFINDER00000006703 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12497304:12501080:-1 10/11 None
T21B4.4 ENSEMBL cdna:known chromosome:CEL140:II:12497179:12502781:-1 gene:T21B4.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12497300-12502760(-) 100.0 100.0
Public Domain and Genome References
Gene Title adenosine A1 receptor
Ensembl T21B4.4
Entrez Gene 174890 Entrez gene
SwissProt O18099 EMBL-EBI
WormBase CE26004 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.16100.1.S1_S_AT adenosine A1 receptor cfa
CHICKEN:GGA.4980.1.S1_AT adenosine A1 receptor gga
HG-U133A:205481_AT adenosine A1 receptor hs
HG-U133_PLUS_2:205481_AT adenosine A1 receptor hs
HG-U133A_2:205481_AT adenosine A1 receptor hs
HU35KSUBD:RC_R40017_S_AT adenosine A1 receptor hs
HUGENEFL:L22214_AT adenosine A1 receptor hs
U133_X3P:G4501946_3P_AT adenosine A1 receptor hs
U133_X3P:HS.77867.1.S1_3P_A_AT adenosine A1 receptor hs
HG-U133A_2:216220_S_AT adenosine A1 receptor hs
HG-FOCUS:216220_S_AT adenosine A1 receptor hs
HG-U133_PLUS_2:216220_S_AT adenosine A1 receptor hs
HG-U133A:216220_S_AT adenosine A1 receptor hs
HG-U95AV2:40400_AT adenosine A1 receptor hs
MOUSE430A_2:1435495_AT adenosine A1 receptor mm
MOE430A:1435495_AT adenosine A1 receptor mm
MOUSE430_2:1435495_AT adenosine A1 receptor mm
MU11KSUBB:MSA.14229.0_AT adenosine A1 receptor mm
MG-U74AV2:92374_AT adenosine A1 receptor mm
MG-U74BV2:163668_AT adenosine A1 receptor mm
MOE430A:1427331_AT adenosine A1 receptor mm
MOUSE430A_2:1427331_AT adenosine A1 receptor mm
MOUSE430_2:1427331_AT adenosine A1 receptor mm
RAE230A:1387721_AT adenosine A1 receptor rn
RAT230_2:1387721_AT adenosine A1 receptor rn
RG-U34A:M64299_AT adenosine A1 receptor rn
RN-U34:M64299_AT adenosine A1 receptor rn
RAE230A:1370584_A_AT adenosine A1 receptor rn
RAT230_2:1370584_A_AT adenosine A1 receptor rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03371 Hypothetical protein T21B4.4 [Caenorhabditis elegans] ref|NP_496667.1| T21B4.4 [Caenorhabditis elegans] 0.0
blast CAE74206 Hypothetical protein CBG21888 [Caenorhabditis briggsae] 0.0
blast CAB03371 Hypothetical protein T21B4.4 [Caenorhabditis elegans] ref|NP_496667.1| T21B4.4 [Caenorhabditis elegans] 1.0E-129
blast CAE74206 Hypothetical protein CBG21888 [Caenorhabditis briggsae] 1.0E-124
blast CAB03371 Hypothetical protein T21B4.4 [Caenorhabditis elegans] ref|NP_496667.1| T21B4.4 [Caenorhabditis elegans] 1.0E-111
blast CAE74206 Hypothetical protein CBG21888 [Caenorhabditis briggsae] 1.0E-106
blast XP_394893 PREDICTED: similar to CG9753-PA, partial [Apis mellifera] 4.0E-26
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 1.9E-16
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 3.7E-19
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 6.5E-24
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 5.7E-19
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496667.1 7 5-27,40-62,77-99,182-204,233-255,285-306,321-343
T21B4.4 7 5-27,40-62,77-99,182-204,233-255,285-306,321-343
SNAP00000006686 3 44-66,96-117,132-154
GENEFINDER00000006703 4 226-248,277-299,329-350,365-387
Sequence
Target Sequence 
>C. ELEGANS:190222_S_AT
tcttctcgacaatcttagcgccaaccgctattatagtattactgtactcaagtatataca
gtagaatccggacggaagagaagcaggtcaagtgcctgctgcggcaatcagagagagaac
gtcggatggcgggaaggcggaagttgattcgaattttattgattttagttgtgtcctatg
ggatttgttggtaccccttgtacattatcaacacgattgactacttttggccggaatttt
caatcaatagcctcactttatggaccgttatcatgtcacacatgtcttgcgcgctgaatc
cgctgatctacgcatacggtatgccgggattcaagaaggtaacaaaaatcagtgagaaat
ctacagtaaaagaagttatttttcaggctctccgagcattcttcaacattcaaactgata
acaacacctgtgcaaactactcgtgttatatgagatcaaccgcaaaccaaaagcagcgga
gcatcagcgtgcgtggcatgccatacgaaacctcgcttgccgcaattcggaaaatttccg
ctccaactccg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCTTCTCGACAATCTTAGCGCCAAC 278 617 722 Antisense
TCAAGTGCCTGCTGCGGCAATCAGA 578 629 809 Antisense
GGATTTGTTGGTACCCCTTGTACAT 144 507 902 Antisense
ACACGATTGACTACTTTTGGCCGGA 680 103 932 Antisense
TAGCCTCACTTTATGGACCGTTATC 272 651 969 Antisense
TCATGTCACACATGTCTTGCGCGCT 203 623 992 Antisense
GAATCCGCTGATCTACGCATACGGT 509 329 1017 Antisense
TTCAGGCTCTCCGAGCATTCTTCAA 417 687 1103 Antisense
AAAGCAGCGGAGCATCAGCGTGCGT 614 123 1191 Antisense
TCAGCGTGCGTGGCATGCCATACGA 496 623 1205 Antisense
TCGGAAAATTTCCGCTCCAACTCCG 559 605 1248 Antisense
Sequence Source Affymetrix Proprietary Database