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[190201_s_at] ras-related protein

Description T25G12.4 /REP_DB=WormBase Gene ID /WP=CE07541 /TR=Q22782 /GB=AAC69020.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=ras-related protein
Cluster 6grp_highest_10_10 > 03      6grp_high1_10_10 > 11      4grp_highest_8_8 > 01      4grp_high_8_8 > 45      6grp_highest_nonorm > 31      6grp_total > 32      4grp_total > 50      6grp_highest_sub > De      6grp_cgc > 61      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Hat      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1102
1 2 3 4 range
A 814.1
(-2.9)
P 		1718.8
(3)
P 		1243.5
(-0.1)
P 		801.7
(-3)
P 		917
B 744.4
(-3)
P 		1383.4
(3)
P 		1288.2
(2.1)
P 		740.2
(-3)
P 		643
C 806.6
(-1.3)
P 		1291.8
(3)
P 		1218
(2.3)
P 		617.3
(-3)
P 		675
avr 788.4
(-2.4) 		1464.7
(3) 		1249.9
(1.3) 		719.7
(-3) 		745

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 660
1 2 3 4 5 6 range
A 1152.8
(3)
P 		1006.8
(1.6)
P 		1061.6
(2.1)
P 		846.2
(-0)
P 		743.1
(-1)
P 		540
(-3)
P 		613
B 1184.1
(3)
P 		976.7
(1.1)
P 		1158.8
(2.8)
P 		1091.9
(2.2)
P 		697.1
(-1.4)
P 		524.6
(-3)
P 		660
C 938.9
(1.4)
P 		1084.1
(3)
P 		992
(2)
P 		857.3
(0.5)
P 		726.6
(-1)
P 		544.3
(-3)
P 		540
avr 1091.9
(3) 		1022.5
(2.3) 		1070.8
(2.8) 		931.8
(1.3) 		722.3
(-1) 		536.3
(-3) 		556
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 320
1 2 3 4 range
A 296.4
(1.2)
P 		373.1
(3)
P 		325.1
(1.9)
P 		117.4
(-3)
P 		256
B 237.4
(-0.4)
P 		341.7
(3)
P 		298.5
(1.6)
P 		157.7
(-3)
P 		184
C 267
(0.1)
P 		371.4
(2)
P 		424.5
(3)
P 		104.1
(-3)
P 		320
avr 266.9
(0.6) 		362.1
(3) 		349.4
(2.7) 		126.4
(-3) 		236

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 281
1 2 3 4 5 6 range
A 212.5
(-0.9)
P 		358.1
(3)
P 		231.2
(-0.4)
P 		214.6
(-0.8)
P 		224.2
(-0.5)
P 		131.5
(-3)
P 		227
B 412
(3)
P 		325.1
(0.6)
P 		281.4
(-0.6)
P 		289.2
(-0.4)
P 		283.2
(-0.6)
P 		195.6
(-3)
P 		216
C 348
(3)
P 		330.8
(2.4)
P 		252.5
(-0.3)
P 		172.4
(-3)
P 		235.1
(-0.9)
P 		182.2
(-2.7)
P 		176
avr 324.2
(2.5) 		338
(3) 		255
(0) 		225.4
(-1) 		247.5
(-0.2) 		169.8
(-3) 		168
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190201_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17461
Sequence Type Exemplar sequence
Representative Public ID T25G12.4 NCBI
Target Description T25G12.4 /REP_DB=WormBase Gene ID /WP=CE07541 /TR=Q22782 /GB=AAC69020.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=ras-related protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078389(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078389 NCBI Caenorhabditis elegans RAB family member (rab-6.2) (rab-6.2) mRNA, complete cds. 11/11 A 
GENEFINDER00000027884 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:17222391:17225045:1 11/11 None
T25G12.4 ENSEMBL cdna:known chromosome:CEL140:X:17222387:17224424:1 gene:T25G12.4 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000027869 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:17222390-17224086(+) 100.0 100.0
Public Domain and Genome References
Gene Title ras-related protein
Gene Symbol rab-6.2
Ensembl T25G12.4
Entrez Gene 181759 Entrez gene
SwissProt Q22782 EMBL-EBI
WormBase CE07541 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:12489_AT Ras-related GTP-binding protein, putative at
ATH1-121501:263458_AT Ras-related GTP-binding protein, putative at
CANINE:1605534_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
CANINE:1604621_S_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
CANINE:1588931_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
CANINE:1588347_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
CANINE_2:CFA.1463.1.S1_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
CANINE_2:CFA.14815.1.A1_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
CANINE_2:CFA.20401.1.S1_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
CANINE_2:CFA.20401.1.S1_S_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
CANINE_2:CFAAFFX.9333.1.S1_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
CANINE_2:CFAAFFX.9333.1.S1_S_AT similar to Ras-related protein Rab-6A (Rab-6) cfa
DROSOPHILA_2:1629797_AT Rab-protein 6 dm
DROSGENOME1:143845_AT Rab-protein 6 dm
CHICKEN:GGA.186.1.S1_AT similar to RAB6A, member RAS oncogene family isoform a; Oncogene RAB6; RAB6, member RAS oncogene family; Rab GTPase gga
HG-U133_PLUS_2:201045_S_AT RAB6A, member RAS oncogene family hs
HG-U133A_2:201045_S_AT RAB6A, member RAS oncogene family hs
HG-U133A:201045_S_AT RAB6A, member RAS oncogene family hs
HG-U133_PLUS_2:201048_X_AT RAB6A, member RAS oncogene family hs
HG-U133A:201048_X_AT RAB6A, member RAS oncogene family hs
HG-U133A_2:201048_X_AT RAB6A, member RAS oncogene family hs
HG-U95AV2:622_AT RAB6A, member RAS oncogene family hs
HC-G110:622_AT RAB6A, member RAS oncogene family hs
HG-U133A:201047_X_AT RAB6A, member RAS oncogene family hs
HG-U133_PLUS_2:201047_X_AT RAB6A, member RAS oncogene family hs
HG-U133A_2:201047_X_AT RAB6A, member RAS oncogene family hs
HG-U133_PLUS_2:210406_S_AT RAB6A, member RAS oncogene family hs
HG-U133A:210406_S_AT RAB6A, member RAS oncogene family hs
HG-FOCUS:210406_S_AT RAB6A, member RAS oncogene family hs
HG-U133A_2:210406_S_AT RAB6A, member RAS oncogene family hs
HU35KSUBD:RC_H95393_AT RAB6A, member RAS oncogene family hs
HUGENEFL:M28212_AT RAB6A, member RAS oncogene family hs
U133_X3P:G4506372_3P_A_AT RAB6A, member RAS oncogene family hs
U133_X3P:G12052972_3P_A_AT RAB6A, member RAS oncogene family hs
U133_X3P:HS2.406327.1.S1_3P_X_AT RAB6A, member RAS oncogene family hs
U133_X3P:HS2.406327.1.S1_3P_AT RAB6A, member RAS oncogene family hs
U133_X3P:HS.5636.0.A1_3P_X_AT RAB6A, member RAS oncogene family hs
U133_X3P:HS.5636.0.A1_3P_S_AT RAB6A, member RAS oncogene family hs
U133_X3P:HS.5636.0.A1_3P_AT RAB6A, member RAS oncogene family hs
U133_X3P:HS.5636.0.A1_3P_A_AT RAB6A, member RAS oncogene family hs
U133_X3P:201045_3P_S_AT RAB6A, member RAS oncogene family hs
U133_X3P:1559174_3P_AT RAB6A, member RAS oncogene family hs
HG-U133_PLUS_2:1559174_AT RAB6A, member RAS oncogene family hs
HG-U95AV2:35304_AT RAB6A, member RAS oncogene family hs
HG-U95D:74773_S_AT RAB6A, member RAS oncogene family hs
HG-U133_PLUS_2:1564820_AT RAB6A, member RAS oncogene family hs
HG-U133_PLUS_2:239445_AT RAB6A, member RAS oncogene family hs
HG-U133B:239445_AT RAB6A, member RAS oncogene family hs
HG-U95C:62792_AT RAB6A, member RAS oncogene family hs
HU35KSUBA:H21219_AT RAB6A, member RAS oncogene family hs
HU35KSUBD:RC_AA485970_AT RAB6A, member RAS oncogene family hs
U133_X3P:HS.191718.0.A1_3P_AT RAB6A, member RAS oncogene family hs
MOE430A:1448304_A_AT RAB6, member RAS oncogene family mm
MOUSE430_2:1448304_A_AT RAB6, member RAS oncogene family mm
MOUSE430A_2:1448304_A_AT RAB6, member RAS oncogene family mm
MOE430A:1448305_AT RAB6, member RAS oncogene family mm
MOUSE430A_2:1448305_AT RAB6, member RAS oncogene family mm
MOUSE430_2:1448305_AT RAB6, member RAS oncogene family mm
MOUSE430_2:1447776_X_AT RAB6, member RAS oncogene family mm
MOE430B:1447776_X_AT RAB6, member RAS oncogene family mm
MG-U74AV2:97222_AT RAB6, member RAS oncogene family mm
MG-U74AV2:98927_AT RAB6, member RAS oncogene family mm
MG-U74CV2:168437_I_AT RAB6, member RAS oncogene family mm
MU11KSUBB:MSA.15834.0_S_AT RAB6, member RAS oncogene family, mRNA (cDNA clone IMAGE:3491845) mm
MU11KSUBB:MSA.6251.0_S_AT RAB6, member RAS oncogene family, mRNA (cDNA clone IMAGE:3491845) mm
MU19KSUBA:TC15050_AT RAB6, member RAS oncogene family, mRNA (cDNA clone IMAGE:3491845) mm
MU19KSUBA:TC15224_AT RAB6, member RAS oncogene family, mRNA (cDNA clone IMAGE:3491845) mm
MU19KSUBB:TC34345_AT RAB6, member RAS oncogene family, mRNA (cDNA clone IMAGE:3491845) mm
MU19KSUBC:TC41118_AT RAB6, member RAS oncogene family, mRNA (cDNA clone IMAGE:3491845) mm
MU19KSUBC:TC41118_G_AT RAB6, member RAS oncogene family, mRNA (cDNA clone IMAGE:3491845) mm
MU11KSUBB:W13350_AT RAB6, member RAS oncogene family, mRNA (cDNA clone IMAGE:3491845) mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6886 intracellular protein transport inferred from electronic annotation QuickGO AmiGO
7264 small GTPase mediated signal transduction inferred from electronic annotation QuickGO AmiGO
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC69020 Rab family protein 6.2 [Caenorhabditis elegans] ref|NP_510790.1| RAB family member (rab-6.2) [Caenorhabditis elegans] 1.0E-114
blast CAE69689 Hypothetical protein CBG15944 [Caenorhabditis briggsae] 1.0E-113
blast AAC69020 Rab family protein 6.2 [Caenorhabditis elegans] ref|NP_510790.1| RAB family member (rab-6.2) [Caenorhabditis elegans] 1.0E-111
blast CAE69689 Hypothetical protein CBG15944 [Caenorhabditis briggsae] 1.0E-110
blast EAA13076 ENSANGP00000020507 [Anopheles gambiae str. PEST] ref|XP_317957.1| ENSANGP00000020507 [Anopheles gambiae str. PEST] 5.0E-91
blast EAA13076 ENSANGP00000020507 [Anopheles gambiae str. PEST] ref|XP_317957.1| ENSANGP00000020507 [Anopheles gambiae str. PEST] 4.0E-90
Protein Domains
Database ID Description E-Value
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 3.4E-87
Sequence
Target Sequence 
>C. ELEGANS:190201_S_AT
gttcgtcttcaactttgggacaccgctggacaggaacgtttccgctcactcatcccatcc
tacatccgtgattctacagttgctgttgtggtttatgacatcaccaactccaactctttc
catcaaacttccaagtggattgacgacgtccgtactgagcgtggaagtgatgtaatcatc
atgttggtcggcaacaagaccgatctttccgataagaggcaagtcaccaccgacgaagga
gagagaaaggccaaggagcttaatgtgatgttcatcgagacttctgccaaggccggctac
aatgtgaagcagcttttccgtcgtatcgccggagccctaccaggaatcatcaaggacgac
ccagtggagccaccaaatgtggtcacgatggacccaatccgtca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTCGTCTTCAACTTTGGGACACCG 501 431 187 Antisense
CATCCGTGATTCTACAGTTGCTGTT 413 211 249 Antisense
CAACTCTTTCCATCAAACTTCCAAG 182 187 297 Antisense
CGACGTCCGTACTGAGCGTGGAAGT 635 249 330 Antisense
GGCAACAAGACCGATCTTTCCGATA 165 535 376 Antisense
GTGATGTTCATCGAGACTTCTGCCA 541 483 451 Antisense
CTTCTGCCAAGGCCGGCTACAATGT 512 219 467 Antisense
ATGTGAAGCAGCTTTTCCGTCGTAT 688 47 488 Antisense
CGGAGCCCTACCAGGAATCATCAAG 178 241 516 Antisense
CATCAAGGACGACCCAGTGGAGCCA 654 209 534 Antisense
TGGTCACGATGGACCCAATCCGTCA 189 551 566 Antisense
Sequence Source Affymetrix Proprietary Database