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[190185_at] ATP citrate lyase

Description D1005.1 /REP_DB=WormBase Gene ID /WP=CE06997 /TR=SW:P53585 /GB=AAB00585.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=ATP citrate lyase
Cluster 6grp_highest_10_10 > 25      6grp_high1_10_10 > 52      4grp_highest_8_8 > 10      4grp_high_8_8 > 54      6grp_highest_nonorm > 33      6grp_total > 52      4grp_total > 57      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 979
1 2 3 4 range
A 599
(-2)
P 		1264.7
(2.2)
P 		1395.7
(3)
P 		447.6
(-3)
P 		948
B 556.2
(-2.4)
P 		1229.8
(1.8)
P 		1426.4
(3)
P 		463.6
(-3)
P 		963
C 610
(-2)
P 		1261.8
(2.5)
P 		1336
(3)
P 		459.5
(-3)
P 		877
avr 588.4
(-2.2) 		1252.1
(2.1) 		1386
(3) 		456.9
(-3) 		929

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3028
1 2 3 4 5 6 range
A 913.9
(-2.3)
P 		1962.2
(0.9)
P 		2675.8
(3)
P 		1655.4
(-0.1)
P 		1040.2
(-1.9)
P 		671.8
(-3)
P 		2004
B 802.7
(-2.5)
P 		1451.7
(-1)
P 		3171.8
(3)
P 		1678.1
(-0.5)
P 		978.7
(-2.1)
P 		581.4
(-3)
P 		2590
C 1045.6
(-2)
P 		1587.7
(-0.9)
P 		3580.3
(3)
P 		1429.7
(-1.3)
P 		1098.6
(-1.9)
P 		552.2
(-3)
P 		3028
avr 920.7
(-2.2) 		1667.2
(-0.5) 		3142.6
(3) 		1587.7
(-0.7) 		1039.2
(-2) 		601.8
(-3) 		2541
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 400
1 2 3 4 range
A 218.1
(0.1)
P 		274.5
(1.2)
P 		364.9
(3)
P 		65.5
(-3)
P 		299
B 177.4
(-1)
P 		303.7
(2.3)
P 		330.5
(3)
P 		98.8
(-3)
P 		232
C 201.9
(-1.1)
P 		362.8
(1.4)
P 		465.6
(3)
P 		77.5
(-3)
P 		388
avr 199.1
(-0.7) 		313.7
(1.6) 		387
(3) 		80.6
(-3) 		306

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 748
1 2 3 4 5 6 range
A 168.5
(-2.9)
P 		697.9
(3)
P 		582.7
(1.7)
P 		419.8
(-0.1)
P 		313.9
(-1.3)
P 		163.6
(-3)
P 		534
B 279.3
(-2.3)
P 		483.2
(-0.1)
P 		770.2
(3)
P 		444.5
(-0.5)
P 		397.6
(-1)
P 		216.8
(-3)
P 		553
C 387.6
(-1.3)
P 		484.5
(-0.5)
P 		911.2
(3)
P 		287.5
(-2.2)
P 		355.5
(-1.6)
P 		184.8
(-3)
P 		726
avr 278.5
(-2) 		555.2
(0.9) 		754.7
(3) 		383.9
(-0.9) 		355.7
(-1.2) 		188.4
(-3) 		566
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190185_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18271
Sequence Type Exemplar sequence
Representative Public ID D1005.1 NCBI
Target Description D1005.1 /REP_DB=WormBase Gene ID /WP=CE06997 /TR=SW:P53585 /GB=AAB00585.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=ATP citrate lyase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075879(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075879 NCBI Caenorhabditis elegans D1005.1 (D1005.1) mRNA, complete cds. 11/11 None
SNAP00000027967 ENSEMBL cdna:SNAP chromosome:CEL140:X:1479567:1484082:1 11/11 None
GENEFINDER00000027970 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:1479567:1484082:1 11/11 None
D1005.1 ENSEMBL cdna:known chromosome:CEL140:X:1479537:1484393:1 gene:D1005.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:1479566-1484082(+) 100.0 100.0
Public Domain and Genome References
Gene Title ATP citrate lyase
Ensembl D1005.1
Entrez Gene 180485 Entrez gene
SwissProt P53585 EMBL-EBI
WormBase CE06997 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:248608_AT ATP-citrate synthase, putative / ATP-citrate (pro-S-)-lyase, putative / citrate cleavage enzyme, putative at
CANINE_2:CFA.16841.1.S1_AT similar to ATP citrate lyase isoform 2 cfa
CANINE_2:CFA.18455.1.S1_S_AT similar to ATP citrate lyase isoform 2 cfa
CANINE_2:CFAAFFX.24270.1.S1_S_AT similar to ATP citrate lyase isoform 2 cfa
DROSOPHILA_2:1634006_S_AT ATP citrate lyase dm
DROSGENOME1:143912_AT ATP citrate lyase dm
CHICKEN:GGA.18859.1.S1_AT ATP citrate lyase gga
CHICKEN:GGA.2159.1.S1_AT ATP citrate lyase gga
HG-U133_PLUS_2:210337_S_AT ATP citrate lyase hs
HG-U133A:210337_S_AT ATP citrate lyase hs
HG-U133A_2:210337_S_AT ATP citrate lyase hs
HG-U133_PLUS_2:201128_S_AT ATP citrate lyase hs
HG-U133A:201128_S_AT ATP citrate lyase hs
HG-FOCUS:201128_S_AT ATP citrate lyase hs
HG-U133A_2:201128_S_AT ATP citrate lyase hs
HG-U133_PLUS_2:201127_S_AT ATP citrate lyase hs
HG-U133A_2:201127_S_AT ATP citrate lyase hs
HG-U133A:201127_S_AT ATP citrate lyase hs
HU35KSUBC:RC_H08548_S_AT ATP citrate lyase hs
HUGENEFL:X64330_AT ATP citrate lyase hs
U133_X3P:G603073_3P_S_AT ATP citrate lyase hs
U133_X3P:G4501864_3P_S_AT ATP citrate lyase hs
HG-U95AV2:40881_AT ATP citrate lyase hs
MOE430A:1425326_AT ATP citrate lyase mm
MOUSE430_2:1425326_AT ATP citrate lyase mm
MOUSE430A_2:1425326_AT ATP citrate lyase mm
MOE430A:1451666_AT ATP citrate lyase mm
MOUSE430A_2:1451666_AT ATP citrate lyase mm
MOUSE430_2:1451666_AT ATP citrate lyase mm
MU11KSUBA:AA271471_S_AT ATP citrate lyase mm
MU11KSUBB:MSA.18310.0_S_AT ATP citrate lyase mm
MU11KSUBB:MSA.8346.0_AT ATP citrate lyase mm
MU11KSUBB:MSA.17426.0_S_AT ATP citrate lyase mm
MU11KSUBB:MSA.28960.0_S_AT ATP citrate lyase mm
MU11KSUBB:MSA.7212.0_S_AT ATP citrate lyase mm
MG-U74AV2:160207_AT ATP citrate lyase mm
MG-U74CV2:170897_R_AT ATP citrate lyase mm
MOE430A:1438389_X_AT ATP citrate lyase mm
MOUSE430A_2:1438389_X_AT ATP citrate lyase mm
MOUSE430_2:1438389_X_AT ATP citrate lyase mm
MOE430A:1439459_X_AT ATP citrate lyase mm
MOUSE430A_2:1439459_X_AT ATP citrate lyase mm
MOUSE430_2:1439459_X_AT ATP citrate lyase mm
MOE430B:1446315_AT ATP citrate lyase mm
MOUSE430_2:1446315_AT ATP citrate lyase mm
MOE430A:1439445_X_AT ATP citrate lyase, mRNA (cDNA clone IMAGE:5346507) mm
MOUSE430A_2:1439445_X_AT ATP citrate lyase, mRNA (cDNA clone IMAGE:5346507) mm
MOUSE430_2:1439445_X_AT ATP citrate lyase, mRNA (cDNA clone IMAGE:5346507) mm
RG-U34A:L27075_G_AT ATP citrate lyase rn
RG-U34A:J05210_G_AT ATP citrate lyase rn
RG-U34A:L27075_AT ATP citrate lyase rn
RG-U34A:J05210_AT ATP citrate lyase rn
RAE230A:1367854_AT ATP citrate lyase rn
RAT230_2:1367854_AT ATP citrate lyase rn
RAE230B:1395841_AT ATP citrate lyase rn
RAT230_2:1395841_AT ATP citrate lyase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB00585 Hypothetical protein D1005.1 [Caenorhabditis elegans] ref|NP_508280.1| D1005.1 [Caenorhabditis elegans] sp|P53585|ACLY_CAEEL Probable ATP-citrate synthase (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme) 0.0
blast CAE56725 Hypothetical protein CBG24512 [Caenorhabditis briggsae] 0.0
blast CAB02690 Hypothetical protein B0365.1 [Caenorhabditis elegans] ref|NP_506267.1| B0365.1 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR003781 EMBL-EBI CoA-binding domain 1.4E-31
Pfam IPR005811 EMBL-EBI ATP-citrate lyase/succinyl-CoA ligase 4.5E-77
Sequence
Target Sequence 
>C. ELEGANS:190185_AT
ccgatcacggaccagctgtgtcgggagcccataacactattgtgtgtgctcgtgctggaa
aagatctgatctcttcgctcacgtctggtctactcaccattggtgatcgcttcggaggtg
ccctcgatggagccgctcgtcagttctctgaggcttttgatcaaggatggtcggcgaatc
agtttgtcagcgagatgagaaagaagggaaagcatattatgggaattggacatcgtgtga
agagtatcaacaaccctgacaaacgtgtggagattctgaaaagatttgccatggacaaga
aggagtttgcccaggagacgccgttgttcgagtatgctcttgaggtcgagaagatcacga
ccgccaaaaaaccgaacctcattctcaacgtggacggagcgattgcgatcttattcgtcg
atatccttcgccacagtggcatgttcaccaagcaggaggccgaggagacaatcgagattg
gatcgctcaatgggcttttcgtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCGATCACGGACCAGCTGTGTCGGG 115 265 2705 Antisense
TCGGGAGCCCATAACACTATTGTGT 632 605 2725 Antisense
TCACCATTGGTGATCGCTTCGGAGG 548 625 2798 Antisense
TGGTCGGCGAATCAGTTTGTCAGCG 286 551 2872 Antisense
AGAAGGAGTTTGCCCAGGAGACGCC 423 73 3002 Antisense
GAGACGCCGTTGTTCGAGTATGCTC 600 393 3019 Antisense
ACCTCATTCTCAACGTGGACGGAGC 426 87 3080 Antisense
GGACGGAGCGATTGCGATCTTATTC 227 525 3096 Antisense
TCTTATTCGTCGATATCCTTCGCCA 43 617 3113 Antisense
GCCACAGTGGCATGTTCACCAAGCA 21 279 3134 Antisense
TGGATCGCTCAATGGGCTTTTCGTT 211 551 3183 Antisense
Sequence Source Affymetrix Proprietary Database