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[190180_at] Src homology domain 2

Description F39B2.5 /REP_DB=WormBase Gene ID /WP=CE16011 /TR=O45498 /GB=CAB07386.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Src homology domain 2
Cluster 6grp_total > 58      4grp_total > 43      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 158
1 2 3 4 range
A 380.4
(-3)
A 		413.6
(3)
A 		394
(-0.5)
A 		383.8
(-2.4)
P 		33
B 437.3
(-0.2)
A 		490.2
(3)
P 		408.7
(-2)
A 		392.2
(-3)
P 		98
C 469.1
(0.4)
M 		538.1
(3)
A 		381.6
(-3)
A 		446.8
(-0.5)
P 		157
avr 428.9
(-0.6) 		480.6
(3) 		394.8
(-3) 		407.6
(-2.1) 		86

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 195
1 2 3 4 5 6 range
A 539.7
(3)
A 		404.3
(-2.9)
A 		469.5
(-0.1)
P 		402.9
(-3)
A 		417
(-2.4)
P 		517.7
(2)
P 		137
B 495.8
(0.3)
P 		396.5
(-3)
M 		513.4
(0.8)
P 		404
(-2.8)
M 		461.3
(-0.9)
P 		579.7
(3)
P 		183
C 476.6
(-0.1)
P 		384.5
(-3)
P 		389.6
(-2.8)
A 		417.8
(-1.9)
A 		430.1
(-1.5)
P 		572.1
(3)
P 		188
avr 504
(1) 		395.1
(-3) 		457.5
(-0.7) 		408.2
(-2.5) 		436.1
(-1.5) 		556.5
(3) 		161
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 99
1 2 3 4 range
A 138.5
(3)
A 		89.8
(-0.6)
A 		103
(0.4)
A 		56.2
(-3)
P 		82
B 139.5
(3)
A 		121.1
(1)
P 		94.7
(-1.8)
A 		83.6
(-3)
P 		56
C 155.3
(3)
M 		154.7
(3)
A 		133
(1.3)
A 		75.3
(-3)
P 		80
avr 144.4
(3) 		121.9
(1.1) 		110.2
(0.2) 		71.7
(-3) 		73

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 132
1 2 3 4 5 6 range
A 99.5
(-3)
A 		143.8
(3)
A 		102.3
(-2.6)
P 		102.2
(-2.6)
A 		125.8
(0.6)
P 		126
(0.6)
P 		44
B 172.5
(0.6)
P 		132
(-1.6)
M 		124.7
(-2)
P 		107
(-3)
M 		187.4
(1.4)
P 		216.2
(3)
P 		109
C 176.7
(2.2)
P 		117.3
(-1.1)
P 		99.2
(-2.2)
A 		84
(-3)
A 		139.2
(0.1)
P 		191.5
(3)
P 		108
avr 149.6
(0.9) 		131
(-0.5) 		108.7
(-2.2) 		97.7
(-3) 		150.8
(1) 		177.9
(3) 		80
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190180_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1691
Sequence Type Exemplar sequence
Representative Public ID F39B2.5 NCBI
Target Description F39B2.5 /REP_DB=WormBase Gene ID /WP=CE16011 /TR=O45498 /GB=CAB07386.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Src homology domain 2
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061173(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061173 NCBI Caenorhabditis elegans F39B2.5 (F39B2.5) mRNA, complete cds. 10/11 None
SNAP00000018503 ENSEMBL cdna:SNAP chromosome:CEL140:I:14783373:14784755:-1 10/11 None
GENEFINDER00000018512 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:14783373:14784755:-1 10/11 None
F39B2.5.2 ENSEMBL cdna:known chromosome:CEL140:I:14783342:14784783:-1 gene:F39B2.5 10/11 None
F39B2.5.1 ENSEMBL cdna:known chromosome:CEL140:I:14783349:14784781:-1 gene:F39B2.5 10/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:14783303-14784686(-) 100.0 100.0
Public Domain and Genome References
Gene Title Src homology domain 2
Ensembl F39B2.5
Entrez Gene 185487 Entrez gene
SwissProt O45498 EMBL-EBI
WormBase CE34485 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07386 Hypothetical protein F39B2.5 [Caenorhabditis elegans] ref|NP_493574.2| F39B2.5 [Caenorhabditis elegans] 1.0E-95
blast CAE72574 Hypothetical protein CBG19761 [Caenorhabditis briggsae] 6.0E-43
Protein Domains
Database ID Description E-Value
Pfam IPR000980 EMBL-EBI SH2 motif 5.9E-11
Sequence
Target Sequence 
>C. ELEGANS:190180_AT
gatagagtctatcattcgcgcttgtcacttgaagattcacgacggaatttgggtagtcgg
cagccatacgtctcacgtgactattggaatcttgtggaaattattgagagaagtttagag
aaaaaaattaaaaaatcaccatttttgttcacaaaaaaaaccacattcccgaaagaaaat
agttcagttttttcagaaattagtttttttttcaaaaatccgaaaaaaactgagtttttc
aagcaaaaaaataatttaatgtttcaaaaatcaaaaaaaatcgtagtttttcggaaaaaa
acactaaacttttttcagcaatccctaacaggacaacaagaaatgctccactatcgacgt
ggacatgaagccgaagcagcgcgtgtcaatttaacacgtccactcacaaaacgagagctt
ctaccatcactacagtacctctgtcgatttaccctgaaaacgagtcaacaaaaaccaccg
acacccaaaacagctcctctgccaccaacgattttaaag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATAGAGTCTATCATTCGCGCTTGT 247 425 184 Antisense
CGCGCTTGTCACTTGAAGATTCACG 645 255 200 Antisense
TGGGTAGTCGGCAGCCATACGTCTC 614 551 233 Antisense
AACTTTTTTCAGCAATCCCTAACAG 572 137 490 Antisense
ACAAGAAATGCTCCACTATCGACGT 529 113 519 Antisense
AAGCCGAAGCAGCGCGTGTCAATTT 292 149 551 Antisense
TCAATTTAACACGTCCACTCACAAA 532 633 569 Antisense
AAAACGAGAGCTTCTACCATCACTA 185 131 591 Antisense
ACCATCACTACAGTACCTCTGTCGA 89 87 606 Antisense
CCTCTGTCGATTTACCCTGAAAACG 380 265 621 Antisense
TCCTCTGCCACCAACGATTTTAAAG 702 591 678 Antisense
Sequence Source Affymetrix Proprietary Database