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[190113_at]

Description R57.1 /REP_DB=WormBase Gene ID /WP=CE12844 /TR=P91406 /GB=AAB52660.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=trans-membrane protein
Cluster 6grp_highest_10_10 > 38      6grp_high1_10_10 > 72      4grp_highest_8_8 > 25      4grp_high_8_8 > 59      6grp_highest_nonorm > 56      6grp_total > 73      4grp_total > 60      6grp_highest_sub > 04      6grp_high1_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1577
1 2 3 4 range
A 2258.1
(2.3)
P 		2187.6
(2)
P 		2414
(3)
P 		1066.2
(-3)
P 		1348
B 2291.4
(2.9)
P 		2079.9
(2)
P 		2320.4
(3)
P 		836.7
(-3)
P 		1484
C 2106.5
(2.9)
P 		1962.3
(2.2)
P 		2123.5
(3)
P 		839.2
(-3)
P 		1284
avr 2218.7
(2.7) 		2076.6
(2.1) 		2286
(3) 		914
(-3) 		1372

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1114
1 2 3 4 5 6 range
A 1580.8
(-3)
P 		2003.8
(-0)
P 		2120.5
(0.8)
P 		2434.3
(3)
P 		2168.7
(1.1)
P 		2154.9
(1)
P 		854
B 1785.1
(-3)
P 		1858.8
(-2.4)
P 		2152.7
(0.1)
P 		2501.9
(3)
P 		2059.4
(-0.7)
P 		1990.1
(-1.3)
P 		717
C 1500.1
(-3)
P 		1895
(-0.9)
P 		2613.8
(3)
P 		2568.8
(2.8)
P 		1914.8
(-0.8)
P 		1709.5
(-1.9)
P 		1114
avr 1622
(-3) 		1919.2
(-1) 		2295.7
(1.6) 		2501.7
(3) 		2047.6
(-0.1) 		1951.5
(-0.8) 		880
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 681
1 2 3 4 range
A 822.2
(3)
P 		474.9
(-0.1)
P 		631.1
(1.3)
P 		156.1
(-3)
P 		666
B 730.7
(3)
P 		513.7
(0.6)
P 		537.7
(0.9)
P 		178.3
(-3)
P 		552
C 697.3
(2.6)
P 		564.2
(1.2)
P 		740.1
(3)
P 		141.5
(-3)
P 		599
avr 750.1
(3) 		517.6
(0.6) 		636.3
(1.8) 		158.6
(-3) 		592

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 545
1 2 3 4 5 6 range
A 291.4
(-3)
P 		712.7
(3)
P 		461.8
(-0.6)
P 		617.4
(1.6)
P 		654.4
(2.2)
P 		524.6
(0.3)
P 		421
B 621.1
(-1.1)
P 		618.7
(-1.2)
P 		522.7
(-3)
P 		662.7
(-0.3)
P 		836.7
(3)
P 		742.1
(1.2)
P 		314
C 556
(-1.4)
P 		578.2
(-0.5)
P 		665.2
(3)
P 		516.6
(-3)
P 		619.6
(1.2)
P 		572.3
(-0.8)
P 		149
avr 489.5
(-3) 		636.5
(1.1) 		549.9
(-1.3) 		598.9
(0.1) 		703.6
(3) 		613
(0.5) 		214
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190113_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18617
Sequence Type Exemplar sequence
Representative Public ID R57.1 NCBI
Target Description R57.1 /REP_DB=WormBase Gene ID /WP=CE12844 /TR=P91406 /GB=AAB52660.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=trans-membrane protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075684(11), NM_001029695(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075684 NCBI Caenorhabditis elegans R57.1a (R57.1) mRNA, complete cds. 11/11 None
NM_001029695 NCBI Caenorhabditis elegans R57.1c (R57.1) mRNA, complete cds. 11/11 None
SNAP00000036377 ENSEMBL cdna:SNAP chromosome:CEL140:X:306933:308231:1 11/11 None
GENEFINDER00000036384 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:307643:314627:1 10/11 None
R57.1a ENSEMBL cdna:known chromosome:CEL140:X:301832:308296:1 gene:R57.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_182448 1/11 Cross Hyb Matching Probes None
R57.1b.2 1/11 Cross Hyb Matching Probes None
R57.1b.1 1/11 Cross Hyb Matching Probes None
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
180386 3 2 NM_001029695 190113_at (11)
NM_075684 190113_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:302766-308231(+) 100.0 100.0
Public Domain and Genome References
Ensembl R57.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast NP_508085 R57.1a [Caenorhabditis elegans] gb|AAU05546.1| Hypothetical protein R57.1a [Caenorhabditis elegans] sp|P91406|GCP2_CAEEL Glutamate carboxypeptidase II homolog 0.0
blast NP_001024866 R57.1c [Caenorhabditis elegans] gb|AAX88809.1| Hypothetical protein R57.1c [Caenorhabditis elegans] 0.0
blast Q5WN23 Glutamate carboxypeptidase II homolog emb|CAE63676.1| Hypothetical protein CBG08178 [Caenorhabditis briggsae] 0.0
blast NP_001024866 R57.1c [Caenorhabditis elegans] gb|AAX88809.1| Hypothetical protein R57.1c [Caenorhabditis elegans] 1.0E-108
Protein Domains
Database ID Description E-Value
Pfam IPR007365 EMBL-EBI Transferrin receptor-like dimerisation domain 1.2E-53
Pfam IPR007484 EMBL-EBI Peptidase M28 1.2E-118
Pfam IPR003137 EMBL-EBI Protease-associated PA 6.5E-29
Pfam IPR007365 EMBL-EBI Transferrin receptor-like dimerisation domain 1.2E-53
Pfam IPR007484 EMBL-EBI Peptidase M28 1.2E-118
Pfam IPR003137 EMBL-EBI Protease-associated PA 6.5E-29
Pfam IPR007365 EMBL-EBI Transferrin receptor-like dimerisation domain 1.2E-53
Pfam IPR007484 EMBL-EBI Peptidase M28 8.9E-8
Pfam IPR007365 EMBL-EBI Transferrin receptor-like dimerisation domain 3.2E-52
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508085.2 1 21-43
NP_001024866.1 1 5-24
R57.1a 1 21-43
Sequence
Target Sequence 
>C. ELEGANS:190113_AT
tgtacgagacgccgttttccaacattcatctattggatacagacaacttatcagtgcaca
aagcaattgggcagtattgggctgagttggcgaagacgtttgcggatgatgtaattctcc
caatgaataccacacattttgcgtcagtcatgctgaaaacctatctcccacaactgaaaa
caacaatctccggaataaatgtttcgagaagcgatttcgaagatatacgcacacagtatg
cacttctctcaaaaagtgctcaagatttacttacaatgtcaaaaaaattccaagaaacca
tccattttacacaacacagcttctctcagaatccatacgacccgaaacacgtgaatgcgg
tcaatgagagattaaagagcacggaaagatgcttcatcaacccccgtggcgtttcaatgc
acaatccctcagctagacatgtcctgttttcagtcagcgattctgattcatactcgagtt
ctttaatggcaggagtacagaatgcgatcaacagttacgacttgaatccaaccaaaaaag
gcttgagggaaataatcaaccaaatctccattgtccagtactctg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGTACGAGACGCCGTTTTCCAACAT 311 559 1646 Antisense
GAATACCACACATTTTGCGTCAGTC 103 327 1770 Antisense
CAGTCATGCTGAAAACCTATCTCCC 663 207 1790 Antisense
TACGCACACAGTATGCACTTCTCTC 481 649 1871 Antisense
TTTACACAACACAGCTTCTCTCAGA 198 673 1951 Antisense
TTCTCTCAGAATCCATACGACCCGA 101 693 1966 Antisense
GTGGCGTTTCAATGCACAATCCCTC 47 493 2051 Antisense
CAATCCCTCAGCTAGACATGTCCTG 479 181 2067 Antisense
GACATGTCCTGTTTTCAGTCAGCGA 201 369 2081 Antisense
GATTCTGATTCATACTCGAGTTCTT 520 431 2104 Antisense
CAAATCTCCATTGTCCAGTACTCTG 628 193 2206 Antisense
Sequence Source Affymetrix Proprietary Database