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[190105_at] RAS-related protein

Description C54A12.4 /REP_DB=WormBase Gene ID /WP=CE01868 /TR=Q09930 /GB=AAA68305.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=RAS-related protein
Cluster 6grp_highest_10_10 > 23      6grp_high1_10_10 > 31      4grp_high_8_8 > 10      6grp_highest_nonorm > 71      6grp_total > 34      4grp_total > 22      6grp_highest_sub > 01_02_03      6grp_cgc > 44      6grp_high1_sub > 03      6grp_cgc_sub > 02      6grp_total_sub > Decrease      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 435
1 2 3 4 range
A 517.8
(3)
P
154.2
(-2)
P
82.6
(-3)
M
353.1
(0.7)
P
435
B 424.7
(1.8)
P
125.5
(-3)
P
125.3
(-3)
P
500.2
(3)
P
375
C 446
(2.2)
P
121.9
(-3)
P
123.1
(-3)
P
493.9
(3)
P
372
avr 462.8
(3)
133.9
(-2.6)
110.3
(-3)
449.1
(2.8)
353

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 370
1 2 3 4 5 6 range
A 368.3
(-0)
P
287.3
(-1.4)
P
556.2
(3)
P
197.9
(-2.8)
P
303.3
(-1.1)
P
186
(-3)
P
370
B 397.3
(0.3)
P
469.2
(1.7)
P
533.4
(3)
P
229.8
(-3)
P
303
(-1.6)
P
258.1
(-2.4)
P
304
C 316.2
(-0.1)
P
445.6
(3)
P
258
(-1.5)
P
252.3
(-1.7)
P
196.9
(-3)
P
272.1
(-1.2)
P
249
avr 360.6
(0.6)
400.7
(1.7)
449.2
(3)
226.7
(-3)
267.7
(-1.9)
238.7
(-2.7)
223
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 167
1 2 3 4 range
A 188.5
(3)
P
33.5
(-2.6)
P
21.6
(-3)
M
51.7
(-1.9)
P
167
B 135.4
(3)
P
31
(-2.9)
P
29
(-3)
P
106.6
(1.4)
P
106
C 147.7
(3)
P
35.1
(-3)
P
42.9
(-2.6)
P
83.3
(-0.4)
P
113
avr 157.2
(3)
33.2
(-2.9)
31.2
(-3)
80.5
(-0.7)
126

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 111
1 2 3 4 5 6 range
A 67.9
(-1.2)
P
102.2
(1.5)
P
121.1
(3)
P
50.2
(-2.6)
P
91.5
(0.7)
P
45.3
(-3)
P
76
B 138.2
(1.9)
P
156.2
(3)
P
129.5
(1.3)
P
60.9
(-3)
P
123.1
(0.9)
P
96.3
(-0.8)
P
95
C 117.2
(1.7)
P
136
(3)
P
65.7
(-1.9)
P
50.7
(-3)
P
63.7
(-2.1)
P
91.1
(-0.2)
P
85
avr 107.8
(1.2)
131.5
(3)
105.4
(1)
53.9
(-3)
92.8
(0)
77.6
(-1.2)
78
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190105_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5677
Sequence Type Exemplar sequence
Representative Public ID C54A12.4 NCBI
Target Description C54A12.4 /REP_DB=WormBase Gene ID /WP=CE01868 /TR=Q09930 /GB=AAA68305.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=RAS-related protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062588(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_062588 NCBI Caenorhabditis elegans Di-Ras/Rig/Noey2 Ras-like protein homolog family member (drn-1) (drn-1) mRNA, complete cds. 11/11 None
SNAP00000020502 ENSEMBL cdna:SNAP chromosome:CEL140:II:5270457:5271682:-1 11/11 None
GENEFINDER00000020507 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:5270457:5271615:-1 11/11 None
C54A12.4 ENSEMBL cdna:known chromosome:CEL140:II:5270457:5271615:-1 gene:C54A12.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:5270454-5271613(-) 100.0 100.0
Public Domain and Genome References
Gene Title RAS-related protein
Gene Symbol drn-1
Ensembl C54A12.4
Entrez Gene 183765 Entrez gene
SwissProt Q09930 EMBL-EBI
WormBase CE01868 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.4148.1.S1_AT similar to GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) cfa
DROSOPHILA_2:1635009_AT dm
DROSGENOME1:149588_AT dm
HG-U133_PLUS_2:219619_AT DIRAS family, GTP-binding RAS-like 2 hs
HG-U133A:219619_AT DIRAS family, GTP-binding RAS-like 2 hs
HG-U133A_2:219619_AT DIRAS family, GTP-binding RAS-like 2 hs
HU35KSUBB:RC_AA084085_AT DIRAS family, GTP-binding RAS-like 2 hs
HU35KSUBC:RC_H29470_AT DIRAS family, GTP-binding RAS-like 2 hs
U133_X3P:G8922160_3P_AT DIRAS family, GTP-binding RAS-like 2 hs
HG-U95C:62275_AT DIRAS family, GTP-binding RAS-like 2 hs
HG-U95C:62704_AT DIRAS family, GTP-binding RAS-like 2 hs
MG-U74BV2:112876_AT similar to Di-Ras2 mm
MOE430B:1455436_AT similar to Di-Ras2 mm
MOUSE430_2:1455436_AT similar to Di-Ras2 mm
MOE430B:1445473_AT similar to Di-Ras2 mm
MOUSE430_2:1445473_AT similar to Di-Ras2 mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7264 small GTPase mediated signal transduction inferred from electronic annotation QuickGO AmiGO
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA68305 Hypothetical protein C54A12.4 [Caenorhabditis elegans] ref|NP_494989.1| Di-Ras/Rig/Noey2 Ras-like protein homolog family member (drn-1) [Caenorhabditis elegans] 1.0E-112
blast AAA68305 Hypothetical protein C54A12.4 [Caenorhabditis elegans] ref|NP_494989.1| Di-Ras/Rig/Noey2 Ras-like protein homolog family member (drn-1) [Caenorhabditis elegans] 2.0E-99
blast CAE59074 Hypothetical protein CBG02361 [Caenorhabditis briggsae] 2.0E-83
blast AAF54453 CG8500-PA [Drosophila melanogaster] ref|NP_649948.1| CG8500-PA [Drosophila melanogaster] 3.0E-60
Protein Domains
Database ID Description E-Value
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 6.2E-48
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 6.2E-48
Sequence
Target Sequence
>C. ELEGANS:190105_AT
gtagcgaggcgtcgacctcggactaccgtgtcgccgtattcggcgcgggtggagttggaa
aatcatcgataacgcagcgatttgtaaaaggaacattcaatgagaattatgttccaacta
tcgaagatacctatcgacaagtgatcagttgcaatcagaagaatgtgtgcactcttcaaa
tcacagatacaaccggaagtcatcagtttcctgcgatgcaaagactgtcgatcagcaagg
gaaatgcatttattctcatttatagcgttacgaataagcagtcatttgctgagctagtac
cgattattgaaatgatgaaggaagtaaaggggaatgcaattgctgaaacgccaataatgc
tcgttggaaacaaaaaagatgaagaatcaaaacgagaagtctcttcaaactctggacaga
aagttgcaacaaatatggaatgtggcttcatcgagacatccgcgaaaaacaacgaaaaca
tcacagaactatttcagcagcttcttgcactggaa


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
GTAGCGAGGCGTCGACCTCGGACTA 623 457 80 Antisense
ACTACCGTGTCGCCGTATTCGGCGC 606 101 101 Antisense
CGTATTCGGCGCGGGTGGAGTTGGA 190 247 114 Antisense
GATACCTATCGACAAGTGATCAGTT 326 425 205 Antisense
AGAATGTGTGCACTCTTCAAATCAC 226 75 239 Antisense
AACCGGAAGTCATCAGTTTCCTGCG 338 145 270 Antisense
GTTTCCTGCGATGCAAAGACTGTCG 463 451 285 Antisense
GCAGTCATTTGCTGAGCTAGTACCG 629 311 357 Antisense
GAAGTCTCTTCAAACTCTGGACAGA 216 337 475 Antisense
TGGCTTCATCGAGACATCCGCGAAA 577 543 522 Antisense
ATTTCAGCAGCTTCTTGCACTGGAA 494 15 570 Antisense
Sequence Source Affymetrix Proprietary Database