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[190027_at] serine/threonine kinase

Description M7.7 /REP_DB=WormBase Gene ID /WP=CE03487 /TR=Q21590 /GB=CAA92744.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 99      4grp_total > 0      6grp_total_sub > Increase      6grp_rule_based > S5      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 28
1 2 3 4 range
A 8.6
(-2.5)
A 		6.2
(-3)
A 		13.9
(-1.4)
A 		34.3
(3)
A 		28
B 8.1
(-1.7)
A 		11.6
(0.5)
A 		6.1
(-3)
A 		15.5
(3)
A 		9
C 16.3
(-1.6)
A 		14.7
(-3)
A 		21.8
(3)
A 		16.5
(-1.5)
A 		7
avr 11
(-2.9) 		10.8
(-3) 		13.9
(-1.4) 		22.1
(3) 		11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 73
1 2 3 4 5 6 range
A 10.4
(-2.5)
A 		4.8
(-2.9)
A 		4.1
(-3)
A 		6.2
(-2.8)
A 		76.7
(3)
A 		36
(-0.4)
A 		73
B 6.9
(-2.9)
A 		8.8
(-2.7)
A 		6.1
(-3)
A 		11.1
(-2.4)
A 		49.1
(1.9)
A 		59
(3)
A 		53
C 6.7
(-3)
A 		15
(-2.2)
A 		14.7
(-2.3)
A 		6.7
(-3)
A 		71.1
(3)
A 		50.7
(1.1)
A 		64
avr 8
(-3) 		9.5
(-2.8) 		8.3
(-3) 		8
(-3) 		65.6
(3) 		48.6
(1.2) 		58
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 6
1 2 3 4 range
A 3.1
(-0.1)
A 		1.3
(-3)
A 		3.6
(0.7)
A 		5
(3)
A 		4
B 2.6
(0.8)
A 		2.9
(1.7)
A 		1.4
(-3)
A 		3.3
(3)
A 		2
C 5.4
(0.3)
A 		4.2
(-1.3)
A 		7.6
(3)
A 		2.8
(-3)
A 		5
avr 3.7
(0.9) 		2.8
(-3) 		4.2
(3) 		3.7
(0.9) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 22
1 2 3 4 5 6 range
A 1.9
(-2.7)
A 		1.7
(-2.8)
A 		0.9
(-3)
A 		1.6
(-2.8)
A 		23.1
(3)
A 		8.8
(-0.9)
A 		22
B 2.4
(-2.7)
A 		2.9
(-2.6)
A 		1.5
(-3)
A 		2.9
(-2.6)
A 		20
(2.4)
A 		22
(3)
A 		21
C 2.5
(-2.7)
A 		4.6
(-2.1)
A 		3.7
(-2.4)
A 		1.4
(-3)
A 		23
(3)
A 		17
(1.3)
A 		22
avr 2.3
(-2.9) 		3.1
(-2.7) 		2
(-3) 		2
(-3) 		22
(3) 		15.9
(1.2) 		20
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190027_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10095
Sequence Type Exemplar sequence
Representative Public ID M7.7 NCBI
Target Description M7.7 /REP_DB=WormBase Gene ID /WP=CE03487 /TR=Q21590 /GB=CAA92744.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069667(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069667 NCBI Caenorhabditis elegans M7.7 (M7.7) mRNA, complete cds. 11/11 None
SNAP00000010383 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11086098:11091807:1 11/11 None
GENEFINDER00000010392 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11089934:11091807:1 11/11 None
M7.7 ENSEMBL cdna:known chromosome:CEL140:IV:11089934:11091807:1 gene:M7.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11089939-11091813(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl M7.7
Entrez Gene 187456 Entrez gene
SwissProt Q21590 EMBL-EBI
WormBase CE03487 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92744 Hypothetical protein M7.7 [Caenorhabditis elegans] ref|NP_502068.1| M7.7 [Caenorhabditis elegans] 0.0
blast CAE61996 Hypothetical protein CBG06004 [Caenorhabditis briggsae] 1.0E-150
blast CAE64723 Hypothetical protein CBG09510 [Caenorhabditis briggsae] 2.0E-41
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 6.7E-10
Pfam IPR000719 EMBL-EBI Protein kinase 6.7E-10
Sequence
Target Sequence 
>C. ELEGANS:190027_AT
aatcgagacgtcatctctacttgttagatttcggaatgagcaaaatttatgtggaaaagg
atgggacattgaaagcaagaagaacatctgctccattcagaggaactcttagatatgtct
ctgtcaatattcatcgtagacaggatgcaagccgctgggatgatatctggagtgcattct
acattgccactgagaatatggtcggacatttgccatggcgtcgaatgggagatgcgatga
aagttgaagagaaaaaagtttcttctgatctttctcgtctcatatatggatcggaccgta
gtcggcccaaatgcatggaatacattgaaaatgaattgaacaactcacaatctgatcctt
catacttttatgtgccaccagcctacgacaagatgcttcaacaaattgctggtgaccttc
gtcttcggaacttgtcaatggatacggtttgcttagattggatgactcgacaatacaaac
caactgatcaatacgtggctcataatccatacgctgttttg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATCGAGACGTCATCTCTACTTGTT 365 169 494 Antisense
GACAGGATGCAAGCCGCTGGGATGA 327 369 632 Antisense
GGAGTGCATTCTACATTGCCACTGA 216 517 662 Antisense
GTCGGACATTTGCCATGGCGTCGAA 103 473 694 Antisense
TTCTGATCTTTCTCGTCTCATATAT 236 695 756 Antisense
TATGGATCGGACCGTAGTCGGCCCA 605 531 778 Antisense
GAACAACTCACAATCTGATCCTTCA 608 351 831 Antisense
ATACTTTTATGTGCCACCAGCCTAC 340 23 855 Antisense
CAAATTGCTGGTGACCTTCGTCTTC 335 193 895 Antisense
ACCTTCGTCTTCGGAACTTGTCAAT 626 81 908 Antisense
GGCTCATAATCCATACGCTGTTTTG 381 539 990 Antisense
Sequence Source Affymetrix Proprietary Database