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[189995_s_at] fumarylacetoacetase

Description K10C2.4 /REP_DB=WormBase Gene ID /WP=CE04750 /TR=Q94272 /GB=AAK39259.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=fumarylacetoacetase
Cluster 6grp_highest_10_10 > 25      6grp_high1_10_10 > 41      4grp_highest_8_8 > 18      4grp_high_8_8 > 62      6grp_highest_nonorm > 24      6grp_total > 41      4grp_total > 56      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2066
1 2 3 4 range
A 2810.8
(-1.9)
P 		3317.1
(0.1)
P 		4059.7
(3)
P 		2516.9
(-3)
P 		1543
B 3264.2
(-0.9)
P 		3248.7
(-1)
P 		4582.7
(3)
P 		2570.6
(-3)
P 		2012
C 2951.2
(-1.2)
P 		3584
(2.1)
P 		3764.1
(3)
P 		2613
(-3)
P 		1151
avr 3008.7
(-1.3) 		3383.3
(0.1) 		4135.5
(3) 		2566.8
(-3) 		1569

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3945
1 2 3 4 5 6 range
A 2457.2
(-1.2)
P 		3421.6
(0.7)
P 		4568
(3)
P 		4087.7
(2)
P 		1915.9
(-2.3)
P 		1583
(-3)
P 		2985
B 2317.5
(-1.2)
P 		3966.7
(2)
P 		4470.7
(3)
P 		3373.5
(0.9)
P 		1998.5
(-1.8)
P 		1395.5
(-3)
P 		3075
C 2964.7
(-0.6)
P 		3271
(-0.1)
P 		5318.9
(3)
P 		3767.2
(0.6)
P 		1937.1
(-2.1)
P 		1374.3
(-3)
P 		3945
avr 2579.8
(-1) 		3553.1
(0.8) 		4785.9
(3) 		3742.8
(1.1) 		1950.5
(-2.1) 		1450.9
(-3) 		3335
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 944
1 2 3 4 range
A 1023.4
(2.7)
P 		720.1
(0)
P 		1061.3
(3)
P 		368.4
(-3)
P 		693
B 1040.9
(2.8)
P 		802.3
(-0)
P 		1061.9
(3)
P 		547.8
(-3)
P 		514
C 976.9
(0.7)
P 		1030.4
(1.1)
P 		1311.9
(3)
P 		440.6
(-3)
P 		871
avr 1013.7
(1.9) 		850.9
(0.5) 		1145
(3) 		452.3
(-3) 		693

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 968
1 2 3 4 5 6 range
A 453
(-2.5)
P 		1216.9
(3)
P 		994.8
(1.4)
P 		1036.7
(1.7)
P 		578.1
(-1.6)
P 		385.4
(-3)
P 		832
B 806.4
(-0.9)
P 		1320.3
(3)
P 		1085.6
(1.2)
P 		893.5
(-0.2)
P 		811.9
(-0.8)
P 		520.4
(-3)
P 		800
C 1098.9
(1.3)
P 		998.1
(0.6)
P 		1353.7
(3)
P 		757.6
(-1)
P 		626.8
(-1.9)
P 		460.1
(-3)
P 		894
avr 786.1
(-0.3) 		1178.4
(3) 		1144.7
(2.7) 		895.9
(0.7) 		672.3
(-1.2) 		455.3
(-3) 		723
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189995_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16559
Sequence Type Exemplar sequence
Representative Public ID K10C2.4 NCBI
Target Description K10C2.4 /REP_DB=WormBase Gene ID /WP=CE04750 /TR=Q94272 /GB=AAK39259.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=fumarylacetoacetase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076682(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076682 NCBI Caenorhabditis elegans K10C2.4 (fumarylacetoacetase) mRNA, complete cds. 11/11 A 
SNAP00000032620 ENSEMBL cdna:SNAP chromosome:CEL140:X:6446787:6448863:-1 11/11 None
GENEFINDER00000032623 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:6446787:6448863:-1 11/11 None
K10C2.4.1 ENSEMBL cdna:known chromosome:CEL140:X:6446604:6448954:-1 gene:K10C2.4 11/11 None
K10C2.4.2 ENSEMBL cdna:known chromosome:CEL140:X:6446604:6448871:-1 gene:K10C2.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:6446786-6448863(-) 100.0 100.0
Public Domain and Genome References
Gene Title fumarylacetoacetase
Ensembl K10C2.4
Entrez Gene 180918 Entrez gene
SwissProt Q94272 EMBL-EBI
WormBase CE04750 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:264396_AT fumarylacetoacetase, putative at
ATGENOME1:19258_AT fumarylacetoacetase, putative at
CANINE:1587265_AT similar to Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) cfa
CANINE_2:CFA.14908.1.A1_AT similar to Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) cfa
CANINE_2:CFA.14908.1.A1_S_AT similar to Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) cfa
DROSOPHILA_2:1638810_AT Fumarylacetoacetase dm
DROSGENOME1:142340_AT Fumarylacetoacetase dm
CHICKEN:GGA.9670.1.S1_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) gga
HG-U133A:202862_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U133A_2:202862_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U133_PLUS_2:202862_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-FOCUS:202862_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HU35KSUBD:RC_W79422_S_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HUGENEFL:M55150_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
U133_X3P:G4557586_3P_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U95AV2:36876_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U133_PLUS_2:236481_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U133B:236481_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HU35KSUBB:RC_T97217_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
U133_X3P:HS.18001.0.S1_3P_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U95B:48002_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
MU11KSUBA:M84145_S_AT fumarylacetoacetate hydrolase mm
MG-U74AV2:98588_AT fumarylacetoacetate hydrolase mm
MOE430A:1417220_AT fumarylacetoacetate hydrolase mm
MOUSE430A_2:1417220_AT fumarylacetoacetate hydrolase mm
MOUSE430_2:1417220_AT fumarylacetoacetate hydrolase mm
MU19KSUBC:TC36660_S_AT Fumarylacetoacetate hydrolase, mRNA (cDNA clone MGC:18569 IMAGE:4242421) mm
RAT230_2:1368092_AT fumarylacetoacetate hydrolase rn
RAE230A:1368092_AT fumarylacetoacetate hydrolase rn
RG-U34A:M77694_AT fumarylacetoacetate hydrolase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
9072 aromatic amino acid family metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
4334 fumarylacetoacetase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK39259 Hypothetical protein K10C2.4 [Caenorhabditis elegans] ref|NP_509083.1| K10C2.4 [Caenorhabditis elegans] 0.0
blast CAE61259 Hypothetical protein CBG05065 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002529 EMBL-EBI Fumarylacetoacetate (FAA) hydrolase 2.5E-115
Sequence
Target Sequence 
>C. ELEGANS:189995_S_AT
ggatcgtatctttggagttgtgctcatgaacgactggagtgctcgcgatatccaagcttg
ggaatacgttccactcggcccattccttgctaaatcctttgccacaactgtttctccatg
ggtcgtctcaattgaagctcttcgtccatactttgttgagaatccagtacaagatccagt
tccaccagcatatctccatcacgatgacccatttacccttgacatcaatttggccgtcag
tatccgtccagaaggagatgctgtggaccatattgtctgtaaaactaacttcaagcattt
gtattggactctaaaacaacaacttgctcaccacaccgtcaatggatgcaacctccgcgc
tggagatcttttgggatcaggaactgtatctggaccagaagaaggtgcatatggatccat
gctcgagctttcgtggcgcggagccaaagaagttccagttggctcagaaatccgaaagtt
cttaaaggacggagatgaggtcaacctttctggagtttgtg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGATCGTATCTTTGGAGTTGTGCTC 134 511 684 Antisense
GAACGACTGGAGTGCTCGCGATATC 288 347 711 Antisense
AGCTTGGGAATACGTTCCACTCGGC 581 75 738 Antisense
AAATCCTTTGCCACAACTGTTTCTC 344 117 775 Antisense
TCTCCATGGGTCGTCTCAATTGAAG 390 609 796 Antisense
GCTCTTCGTCCATACTTTGTTGAGA 146 299 820 Antisense
GCATATCTCCATCACGATGACCCAT 254 309 871 Antisense
ACCCATTTACCCTTGACATCAATTT 228 91 890 Antisense
ATCAATTTGGCCGTCAGTATCCGTC 206 27 907 Antisense
TATGGATCCATGCTCGAGCTTTCGT 54 655 1093 Antisense
GAGGTCAACCTTTCTGGAGTTTGTG 424 403 1180 Antisense
Sequence Source Affymetrix Proprietary Database