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[189987_s_at] zinc metalloprotease

Description C26C6.3 /REP_DB=WormBase Gene ID /WP=CE05312 /TR=Q18206 /GB=CAA96596.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=zinc metalloprotease
Cluster 6grp_total > 74      4grp_total > 48      6grp_cgc > 75      6grp_cgc_sub > 03_04      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 322
1 2 3 4 range
A 36.7
(-3)
P 		271.2
(1.9)
P 		325.2
(3)
P 		41.5
(-2.9)
A 		289
B 31.9
(-3)
A 		239.6
(3)
P 		238.1
(3)
P 		33.5
(-3)
A 		208
C 29.4
(-3)
A 		203.2
(0.2)
P 		350.9
(3)
P 		100.7
(-1.7)
M 		322
avr 32.7
(-3) 		238
(1.5) 		304.7
(3) 		58.6
(-2.4) 		272

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 158
1 2 3 4 5 6 range
A 77.4
(-3)
A 		136.7
(1.1)
P 		129.5
(0.6)
P 		163.9
(3)
P 		152.7
(2.2)
P 		153.5
(2.3)
P 		87
B 39.1
(-3)
A 		144.1
(1.1)
P 		110.5
(-0.2)
P 		194
(3)
P 		143.9
(1.1)
P 		153.9
(1.4)
P 		155
C 38.2
(-3)
A 		136.5
(0.7)
P 		131.3
(0.5)
P 		195.8
(3)
P 		159.5
(1.6)
P 		139.2
(0.8)
P 		158
avr 51.6
(-3) 		139.1
(0.9) 		123.8
(0.3) 		184.6
(3) 		152
(1.5) 		148.9
(1.4) 		133
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 116
1 2 3 4 range
A 13.3
(-2.5)
P 		58.9
(1)
P 		85
(3)
P 		6.1
(-3)
A 		79
B 10.2
(-2.6)
A 		59.2
(3)
P 		55.2
(2.5)
P 		7.1
(-3)
A 		52
C 9.7
(-3)
A 		58.4
(-0.4)
P 		122.3
(3)
P 		17
(-2.6)
M 		113
avr 11.1
(-2.9) 		58.8
(0.8) 		87.5
(3) 		10.1
(-3) 		77

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 45
1 2 3 4 5 6 range
A 14.3
(-3)
A 		48.6
(3)
P 		28.2
(-0.6)
P 		41.6
(1.8)
P 		46.1
(2.6)
P 		37.4
(1)
P 		34
B 13.6
(-3)
A 		48
(1.6)
P 		26.8
(-1.2)
P 		51.4
(2.1)
P 		58.5
(3)
P 		57.4
(2.9)
P 		45
C 14.2
(-3)
A 		41.6
(1.4)
P 		33.4
(0.1)
P 		39.4
(1)
P 		51.6
(3)
P 		46.6
(2.2)
P 		37
avr 14
(-3) 		46.1
(2.1) 		29.5
(-0.6) 		44.1
(1.7) 		52.1
(3) 		47.1
(2.2) 		38
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189987_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1354
Sequence Type Exemplar sequence
Representative Public ID C26C6.3 NCBI
Target Description C26C6.3 /REP_DB=WormBase Gene ID /WP=CE05312 /TR=Q18206 /GB=CAA96596.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=zinc metalloprotease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059708(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059708 NCBI Caenorhabditis elegans Nematode AStacin protease family member (nas-36) (nas-36) mRNA, complete cds. 9/11 None
GENEFINDER00000003877 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7535952:7539516:1 11/11 None
SNAP00000003873 ENSEMBL cdna:SNAP chromosome:CEL140:I:7537115:7539516:1 9/11 None
C26C6.3 ENSEMBL cdna:known chromosome:CEL140:I:7535435:7539827:1 gene:C26C6.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7535365-7539447(+) 100.0 100.0
Public Domain and Genome References
Gene Title zinc metalloprotease
Gene Symbol nas-36
Ensembl C26C6.3
Entrez Gene 172506 Entrez gene
WormBase CE38281 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA96596 Hypothetical protein C26C6.3 [Caenorhabditis elegans] ref|NP_492109.2| Nematode AStacin protease family member (nas-36) [Caenorhabditis elegans] 0.0
blast Q18206 Zinc metalloproteinase nas-36 precursor (Nematode astacin 36) 0.0
blast CAE66571 Hypothetical protein CBG11886 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001506 EMBL-EBI Peptidase M12A, astacin 1.4E-106
Pfam IPR000884 EMBL-EBI Thrombospondin, type I 9.4E-9
Pfam IPR000859 EMBL-EBI CUB 9.9E-12
Pfam IPR001506 EMBL-EBI Peptidase M12A, astacin 1.4E-106
Pfam IPR000884 EMBL-EBI Thrombospondin, type I 9.4E-9
Pfam IPR000859 EMBL-EBI CUB 9.9E-12
Pfam IPR001506 EMBL-EBI Peptidase M12A, astacin 9.4E-63
Pfam IPR000884 EMBL-EBI Thrombospondin, type I 9.4E-9
Pfam IPR000859 EMBL-EBI CUB 9.9E-12
Pfam IPR001506 EMBL-EBI Peptidase M12A, astacin 2.8E-104
Pfam IPR000884 EMBL-EBI Thrombospondin, type I 9.4E-9
Pfam IPR000859 EMBL-EBI CUB 9.9E-12
Sequence
Target Sequence 
>C. ELEGANS:189987_S_AT
gttttgtttctcagactgacactgctattattattttccgatcacaactttctacggata
ttggatttaaaattcaagcaaaatctaatgaattgattattaaaacttttaaaaatagcc
aaaaaaccaaaatgcaaatactttttcctaaactgtctttaaaaaataattcagccgatg
ccgaaccaaggacaacaattgctccaacaattatcacaacaactttggcaccaataactg
ttgatgcaccaaatgtatgggcagattggggtgaatggtcaatgtgttcaagaacatgtg
gaggttgtggaattagaagtcgggtcagatcatgtagaagcaaaaagtgcgagggacgac
gacaagaatttggaacctgtaatttgaaagcgtgccctgttgataaacattgcgcaaagc
tactatcaaataataggctttgcaatggaaaagtgtgtaccaaaaacgacattgcaatat
cgtcatgtgatgctccacaatgttgtcctccgtttattaatgttg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTTTGTTTCTCAGACTGACACTGC 87 449 1385 Antisense
GACACTGCTATTATTATTTTCCGAT 398 367 1402 Antisense
TATTTTCCGATCACAACTTTCTACG 184 661 1416 Antisense
GCAAATACTTTTTCCTAAACTGTCT 116 317 1518 Antisense
AAATAATTCAGCCGATGCCGAACCA 135 115 1548 Antisense
GGCACCAATAACTGTTGATGCACCA 471 535 1611 Antisense
AAGTCGGGTCAGATCATGTAGAAGC 196 157 1701 Antisense
TGAAAGCGTGCCCTGTTGATAAACA 232 573 1769 Antisense
GCAATATCGTCATGTGATGCTCCAC 310 323 1858 Antisense
TGTGATGCTCCACAATGTTGTCCTC 677 555 1870 Antisense
TGTTGTCCTCCGTTTATTAATGTTG 143 561 1885 Antisense
Sequence Source Affymetrix Proprietary Database