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[189974_s_at] t-complex protein 1

Description T21B10.7 /REP_DB=WormBase Gene ID /WP=CE16437 /TR=Q22628 /GB=CAA92697.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=t-complex protein 1
Cluster 6grp_highest_10_10 > 62      6grp_high1_10_10 > 26      4grp_highest_8_8 > 21      4grp_high_8_8 > 23      6grp_highest_nonorm > 02      6grp_total > 25      4grp_total > 16      6grp_highest_sub > Cu      6grp_high1_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4637
1 2 3 4 range
A 3075.4
(-2.3)
P 		2643.4
(-3)
P 		4011.2
(-0.7)
P 		6214.6
(3)
P 		3571
B 2666.1
(-3)
P 		3894.8
(-1.4)
P 		4579.3
(-0.5)
P 		7280.8
(3)
P 		4615
C 3264.2
(-3)
P 		4044.6
(-1.2)
P 		4307.9
(-0.6)
P 		5877.8
(3)
P 		2614
avr 3001.9
(-3) 		3527.6
(-2.1) 		4299.5
(-0.7) 		6457.7
(3) 		3456

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1776
1 2 3 4 5 6 range
A 2639.3
(2)
P 		2824.9
(3)
P 		1971
(-1.7)
P 		1772.6
(-2.8)
P 		1735.6
(-3)
P 		2073.9
(-1.1)
P 		1089
B 3407.6
(3)
P 		2808.1
(0.7)
P 		2877
(0.9)
P 		1860.5
(-3)
P 		1881
(-2.9)
P 		1972.2
(-2.6)
P 		1547
C 3137.7
(3)
P 		2728.2
(1.4)
P 		2323.9
(-0.2)
P 		1631.6
(-3)
P 		2024.2
(-1.4)
P 		2189.4
(-0.8)
P 		1506
avr 3061.5
(3) 		2787.1
(1.7) 		2390.6
(-0.1) 		1754.9
(-3) 		1880.3
(-2.4) 		2078.5
(-1.5) 		1307
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 978
1 2 3 4 range
A 1119.8
(3)
P 		573.8
(-3)
P 		1048.6
(2.2)
P 		909.7
(0.7)
P 		546
B 850.2
(-3)
P 		961.9
(-2)
P 		1061.1
(-1.2)
P 		1551.5
(3)
P 		701
C 1080.5
(-1.9)
P 		1162.8
(-1)
P 		1501.4
(3)
P 		991.1
(-3)
P 		510
avr 1016.8
(-0.7) 		899.5
(-3) 		1203.7
(3) 		1150.8
(2) 		304

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 858
1 2 3 4 5 6 range
A 486.5
(-2.4)
P 		1004.7
(3)
P 		429.2
(-3)
P 		449.6
(-2.8)
P 		523.7
(-2)
P 		504.9
(-2.2)
P 		576
B 1185.7
(3)
P 		934.7
(0.8)
P 		698.6
(-1.2)
P 		492.8
(-3)
P 		764.2
(-0.6)
P 		735.4
(-0.9)
P 		693
C 1163
(3)
P 		832.5
(0.6)
P 		591.5
(-1.1)
P 		328.1
(-3)
P 		655
(-0.7)
P 		732.9
(-0.1)
P 		835
avr 945.1
(3) 		924
(2.8) 		573.1
(-1.3) 		423.5
(-3) 		647.6
(-0.4) 		657.7
(-0.3) 		522
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189974_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3898
Sequence Type Exemplar sequence
Representative Public ID T21B10.7 NCBI
Target Description T21B10.7 /REP_DB=WormBase Gene ID /WP=CE16437 /TR=Q22628 /GB=CAA92697.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=t-complex protein 1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_171985(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_171985 NCBI Caenorhabditis elegans T21B10.7 (T21B10.7) mRNA, complete cds. 11/11 A 
SNAP00000044361 ENSEMBL cdna:SNAP chromosome:CEL140:II:8928515:8929393:1 11/11 None
GENEFINDER00000044374 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8928562:8929393:1 11/11 None
T21B10.7.3 ENSEMBL cdna:known chromosome:CEL140:II:8927645:8929646:1 gene:T21B10.7 11/11 A 
T21B10.7.2 ENSEMBL cdna:known chromosome:CEL140:II:8927649:8929725:1 gene:T21B10.7 11/11 A 
T21B10.7.1 ENSEMBL cdna:known chromosome:CEL140:II:8927651:8929725:1 gene:T21B10.7 11/11 A 
T21B10.7.4 ENSEMBL cdna:known chromosome:CEL140:II:8927651:8929726:1 gene:T21B10.7 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8927651-8929390(+) 100.0 100.0
Public Domain and Genome References
Gene Title t-complex protein 1
Ensembl T21B10.7
Entrez Gene 174421 Entrez gene
SwissProt P47207 EMBL-EBI
WormBase CE16437 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:246191_AT chaperonin, putative at
CANINE:1604348_AT similar to chaperonin containing TCP1, subunit 2 cfa
CANINE:1583199_AT similar to chaperonin containing TCP1, subunit 2 cfa
CANINE_2:CFA.18704.1.S1_S_AT similar to chaperonin containing TCP1, subunit 2 cfa
CANINE_2:CFA.6470.1.A1_AT similar to chaperonin containing TCP1, subunit 2 cfa
CANINE_2:CFAAFFX.6738.1.S1_S_AT similar to chaperonin containing TCP1, subunit 2 cfa
DROSOPHILA_2:1630408_S_AT dm
DROSGENOME1:151740_AT dm
DROSGENOME1:142977_AT dm
CHICKEN:GGA.7759.1.S1_A_AT chaperonin containing TCP1, subunit 2 (beta) gga
HG-U95AV2:35759_AT chaperonin containing TCP1, subunit 2 (beta) hs
HG-U133A_2:201947_S_AT chaperonin containing TCP1, subunit 2 (beta) hs
HG-U133A:201947_S_AT chaperonin containing TCP1, subunit 2 (beta) hs
HG-U133_PLUS_2:201947_S_AT chaperonin containing TCP1, subunit 2 (beta) hs
HG-U133A:201946_S_AT chaperonin containing TCP1, subunit 2 (beta) hs
HG-U133A_2:201946_S_AT chaperonin containing TCP1, subunit 2 (beta) hs
HG-FOCUS:201946_S_AT chaperonin containing TCP1, subunit 2 (beta) hs
HG-U133_PLUS_2:201946_S_AT chaperonin containing TCP1, subunit 2 (beta) hs
HU35KSUBB:RC_N70633_AT chaperonin containing TCP1, subunit 2 (beta) hs
HU35KSUBD:RC_N38959_F_AT chaperonin containing TCP1, subunit 2 (beta) hs
HU35KSUBD:RC_N38959_R_AT chaperonin containing TCP1, subunit 2 (beta) hs
HU35KSUBD:RC_AA488991_S_AT chaperonin containing TCP1, subunit 2 (beta) hs
HUGENEFL:U91327_AT chaperonin containing TCP1, subunit 2 (beta) hs
U133_X3P:G5453602_3P_X_AT chaperonin containing TCP1, subunit 2 (beta) hs
U133_X3P:G5453602_3P_A_AT chaperonin containing TCP1, subunit 2 (beta) hs
U133_X3P:HS.6456.0.S1_3P_A_AT chaperonin containing TCP1, subunit 2 (beta) hs
HG-U95D:87489_AT Chaperonin containing TCP1, subunit 2 (beta) hs
MOE430A:1416037_A_AT chaperonin subunit 2 (beta) mm
MOUSE430A_2:1416037_A_AT chaperonin subunit 2 (beta) mm
MOUSE430_2:1416037_A_AT chaperonin subunit 2 (beta) mm
MU11KSUBB:Z31553_S_AT chaperonin subunit 2 (beta) mm
MG-U74AV2:160442_AT chaperonin subunit 2 (beta) mm
MOE430A:1433535_X_AT chaperonin subunit 2 (beta) mm
MOUSE430A_2:1433535_X_AT chaperonin subunit 2 (beta) mm
MOUSE430_2:1433535_X_AT chaperonin subunit 2 (beta) mm
MOE430A:1433534_A_AT chaperonin subunit 2 (beta) mm
MOUSE430A_2:1433534_A_AT chaperonin subunit 2 (beta) mm
MOUSE430_2:1433534_A_AT chaperonin subunit 2 (beta) mm
MU19KSUBA:TC14520_AT Chaperonin subunit 2 (beta), mRNA (cDNA clone MGC:25091 IMAGE:4500896) mm
MU19KSUBA:TC14521_AT Chaperonin subunit 2 (beta), mRNA (cDNA clone MGC:25091 IMAGE:4500896) mm
RG-U34C:RC_AI233731_AT chaperonin containing TCP1, subunit 2 (beta) rn
RAE230A:1371418_AT chaperonin containing TCP1, subunit 2 (beta) rn
RAT230_2:1371418_AT chaperonin containing TCP1, subunit 2 (beta) rn
YEAST_2:1774928_AT Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo Sc
Protein Similarities
Method ID Description E-Value
blast CAA92697 Hypothetical protein T21B10.7 [Caenorhabditis elegans] emb|CAA20331.1| Hypothetical protein T21B10.7 [Caenorhabditis elegans] ref|NP_741031.1| T21B10.7 [Caenorhabditis elegans] sp|P47207|TCPB_CAEEL T-complex protein 1, beta subunit (TCP-1-beta) (CCT-beta) pir||T18589 chaperonin beta chain - Caenorhabditis elegans 0.0
blast AAA93233 CCT-2 0.0
blast CAE59760 Hypothetical protein CBG03212 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002423 EMBL-EBI Chaperonin Cpn60/TCP-1 9.0E-92
Pfam IPR002423 EMBL-EBI Chaperonin Cpn60/TCP-1 4.4E-90
Pfam IPR002423 EMBL-EBI Chaperonin Cpn60/TCP-1 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:189974_S_AT
tgattcaccacaaactgctcaattcggatcttgtgatctgattgaagagattatgattgg
agaagatagacttcttcggttctcgggagtcaaattgggtgaagcttgctcagtcgttct
tcgtggagcaactcagcagattcttgatgagtccgaaagatccctccatgatgccctttg
tgttctcgttactcacgtgaaagaatcaaagactgttgccggagctggagcgagcgaaat
tttgatgagttcagccatcgccgtcgaagctcaaaaggttgcgggtaaggaagcccttgc
cgttgaagccttcggaagagcccttgctcaattgccaaccatcatttgcgacaatgctgg
acttgactcggctgaacttgtcacaagactccgtgcagagcacgccaatggacgtcaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGATTCACCACAAACTGCTCAATTC 134 565 999 Antisense
TAGACTTCTTCGGTTCTCGGGAGTC 420 651 1065 Antisense
TGAAGCTTGCTCAGTCGTTCTTCGT 703 573 1098 Antisense
TGATGAGTCCGAAAGATCCCTCCAT 247 567 1143 Antisense
CCTTTGTGTTCTCGTTACTCACGTG 607 267 1173 Antisense
CCCTTGCCGTTGAAGCCTTCGGAAG 345 259 1292 Antisense
GAAGAGCCCTTGCTCAATTGCCAAC 623 337 1313 Antisense
AATTGCCAACCATCATTTGCGACAA 252 177 1328 Antisense
GCGACAATGCTGGACTTGACTCGGC 256 289 1346 Antisense
AACTTGTCACAAGACTCCGTGCAGA 677 137 1373 Antisense
GCAGAGCACGCCAATGGACGTCACA 515 311 1393 Antisense
Sequence Source Affymetrix Proprietary Database