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[189956_at] GTP-binding protein

Description W01H2.3 /REP_DB=WormBase Gene ID /WP=CE07562 /TR=O02046 /GB=AAB52888.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=GTP-binding protein
Cluster 6grp_high1_10_10 > 05      6grp_total > 14      4grp_total > 38      6grp_cgc > 31      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 168
1 2 3 4 range
A 133.7
(3)
P 		50.7
(-0.9)
A 		6.5
(-3)
A 		70.6
(0)
A 		127
B 174.4
(3)
P 		58.8
(-2)
A 		36.9
(-3)
A 		57.1
(-2.1)
A 		138
C 150.2
(3)
P 		76.3
(-1)
A 		38.1
(-3)
M 		62.1
(-1.7)
A 		112
avr 152.8
(3) 		61.9
(-1.3) 		27.2
(-3) 		63.3
(-1.3) 		126

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 111
1 2 3 4 5 6 range
A 124.3
(3)
P 		118.4
(2.4)
P 		84.2
(-1)
P 		63.9
(-3)
P 		93.7
(-0)
P 		81.5
(-1.3)
P 		60
B 116.6
(3)
P 		102
(1.7)
P 		112.2
(2.6)
P 		79.7
(-0.2)
P 		64.9
(-1.5)
P 		47.9
(-3)
P 		69
C 158.5
(3)
P 		100.6
(-0.2)
P 		77
(-1.4)
P 		115.9
(0.7)
P 		48.6
(-3)
A 		58.3
(-2.5)
P 		110
avr 133.1
(3) 		107
(0.8) 		91.1
(-0.6) 		86.5
(-1) 		69.1
(-2.4) 		62.6
(-3) 		71
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 54
1 2 3 4 range
A 48.7
(3)
P 		11
(-1.8)
A 		1.7
(-3)
A 		10.3
(-1.9)
A 		47
B 55.6
(3)
P 		14.5
(-2.2)
A 		8.6
(-3)
A 		12.2
(-2.5)
A 		47
C 49.7
(3)
P 		21.9
(-1.3)
A 		13.3
(-2.6)
M 		10.5
(-3)
A 		39
avr 51.3
(3) 		15.8
(-1.9) 		7.9
(-3) 		11
(-2.6) 		43

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 43
1 2 3 4 5 6 range
A 22.9
(-1.4)
P 		42.1
(3)
P 		18.3
(-2.5)
P 		16.2
(-3)
P 		28.3
(-0.2)
P 		19.9
(-2.1)
P 		26
B 40.6
(3)
P 		34
(1.3)
P 		27.2
(-0.5)
P 		21.1
(-2.2)
P 		26.4
(-0.8)
P 		17.9
(-3)
P 		23
C 58.8
(3)
P 		30.7
(-0.9)
P 		19.6
(-2.5)
P 		23.3
(-1.9)
P 		15.7
(-3)
A 		19.5
(-2.5)
P 		43
avr 40.8
(3) 		35.6
(1.6) 		21.7
(-2.3) 		20.2
(-2.7) 		23.5
(-1.8) 		19.1
(-3) 		22
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189956_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16650
Sequence Type Exemplar sequence
Representative Public ID W01H2.3 NCBI
Target Description W01H2.3 /REP_DB=WormBase Gene ID /WP=CE07562 /TR=O02046 /GB=AAB52888.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=GTP-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076320(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076320 NCBI Caenorhabditis elegans RAB family member (rab-37) (rab-37) mRNA, complete cds. 11/11 None
GENEFINDER00000010127 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:4228502:4231346:-1 11/11 None
W01H2.3 ENSEMBL cdna:known chromosome:CEL140:X:4227831:4231196:-1 gene:W01H2.3 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000010125 7/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:4228502-4231197(-) 100.0 100.0
Public Domain and Genome References
Gene Title GTP-binding protein
Gene Symbol rab-37
Ensembl W01H2.3
Entrez Gene 180696 Entrez gene
SwissProt O02046 EMBL-EBI
WormBase CE07562 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.7823.1.S1_AT similar to Ras-related protein Rab-37 cfa
CANINE_2:CFAAFFX.7826.1.S1_AT similar to Ras-related protein Rab-37 cfa
CANINE_2:CFAAFFX.7826.1.S1_S_AT similar to Ras-related protein Rab-37 cfa
DROSOPHILA_2:1623233_AT dm
DROSGENOME1:152856_AT dm
HU35KSUBB:RC_R62453_AT RAB37, member RAS oncogene family hs
U133_X3P:HS.321677.1.S1_3P_AT RAB37, member RAS oncogene family hs
HG-U133_PLUS_2:228113_AT RAB37, member RAS oncogene family hs
HG-U133B:228113_AT RAB37, member RAS oncogene family hs
HG-U95B:47429_AT RAB37, member RAS oncogene family hs
HG-U95D:84874_AT RAB37, member RAS oncogene family hs
U133_X3P:HS.147066.0.A1_3P_AT RAB37, member RAS oncogene family hs
MOUSE430_2:1450167_AT RAB37, member of RAS oncogene family mm
MOE430A:1450167_AT RAB37, member of RAS oncogene family mm
MOUSE430A_2:1450167_AT RAB37, member of RAS oncogene family mm
MG-U74CV2:139223_AT RAB37, member of RAS oncogene family mm
MOE430B:1433947_AT RAB37, member of RAS oncogene family mm
MOUSE430_2:1433947_AT RAB37, member of RAS oncogene family mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6886 intracellular protein transport inferred from electronic annotation QuickGO AmiGO
7264 small GTPase mediated signal transduction inferred from electronic annotation QuickGO AmiGO
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB52888 Rab family protein 37 [Caenorhabditis elegans] ref|NP_508721.1| RAB family member (rab-37) [Caenorhabditis elegans] dbj|BAD32698.1| Rab37 [Caenorhabditis elegans] 1.0E-110
blast AAB52888 Rab family protein 37 [Caenorhabditis elegans] ref|NP_508721.1| RAB family member (rab-37) [Caenorhabditis elegans] dbj|BAD32698.1| Rab37 [Caenorhabditis elegans] 1.0E-108
blast CAE68542 Hypothetical protein CBG14372 [Caenorhabditis briggsae] 2.0E-90
blast CAE68542 Hypothetical protein CBG14372 [Caenorhabditis briggsae] 5.0E-89
blast XP_540417 PREDICTED: similar to Ras-related protein Rab-37 [Canis familiaris] 6.0E-54
blast XP_540417 PREDICTED: similar to Ras-related protein Rab-37 [Canis familiaris] 8.0E-54
Protein Domains
Database ID Description E-Value
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 5.7E-82
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 5.7E-82
Sequence
Target Sequence 
>C. ELEGANS:189956_AT
gctacttggtgacagctgcactggaaaaacgtgccttctgattcgatacaaagatggagc
ttttctaaataacaatttcatttcaacagttggaattgattacagaaataaactaatcac
aatgggagataagaaggtcaaacttcagatttgggacaccgcgggacaagaacgttttcg
atcagtgaccacatcatactaccgcgacgccgatgctcttctcttggtctacgacatcgc
caatcgtgcaagctttgagaactgccggaactggctctctcaaatcaaagaatatgggaa
agaggcggtacaagtgacacttgttggcaacaaatgtgatttgccaagagcagtaccgac
ggatgagggaaaacgtcttgctgaggcctatcaaattccattcatggagacgagcgccaa
aactgggttcaatgtagatagagcattcctcggattggcagaacgaatgctcaagttgaa
atacggttttgttcccggaggtgaaatggcggacacgatttccgtcgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTACTTGGTGACAGCTGCACTGGA 124 303 30 Antisense
AAACGTGCCTTCTGATTCGATACAA 703 125 56 Antisense
GATCAGTGACCACATCATACTACCG 575 419 209 Antisense
TTCTCTTGGTCTACGACATCGCCAA 16 691 248 Antisense
ACATCGCCAATCGTGCAAGCTTTGA 469 105 263 Antisense
CAAGCTTTGAGAACTGCCGGAACTG 616 185 278 Antisense
GGAACTGGCTCTCTCAAATCAAAGA 113 531 296 Antisense
GGAAAACGTCTTGCTGAGGCCTATC 199 527 397 Antisense
GAGGCCTATCAAATTCCATTCATGG 676 405 412 Antisense
GAGCATTCCTCGGATTGGCAGAACG 431 389 470 Antisense
AAATGGCGGACACGATTTCCGTCGC 74 121 533 Antisense
Sequence Source Affymetrix Proprietary Database