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[189907_s_at] dynein heavy chain

Description T21E12.4 /REP_DB=WormBase Gene ID /WP=CE23997 /GEN=dhc-1 /GB=AAK21472.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=dynein heavy chain
Cluster 6grp_highest_10_10 > 51      6grp_high1_10_10 > 16      4grp_highest_8_8 > 49      4grp_high_8_8 > 41      6grp_highest_nonorm > 0      6grp_total > 25      4grp_total > 54      6grp_highest_sub > De      6grp_cgc > 24      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1305
1 2 3 4 range
A 2018.6
(3)
P 		1360.3
(-0.5)
P 		1204.6
(-1.3)
P 		894.7
(-3)
P 		1124
B 2083.1
(3)
P 		1199.9
(-1.3)
P 		1230
(-1.1)
P 		849.6
(-3)
P 		1234
C 1922.1
(3)
P 		1265.8
(-0.4)
P 		1017.5
(-1.7)
P 		777.7
(-3)
P 		1144
avr 2007.9
(3) 		1275.3
(-0.8) 		1150.7
(-1.4) 		840.7
(-3) 		1167

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1712
1 2 3 4 5 6 range
A 2669.1
(3)
P 		1865.2
(-0.2)
P 		1156.7
(-3)
P 		1244.5
(-2.7)
P 		1357
(-2.2)
P 		1472.9
(-1.7)
P 		1512
B 2343
(3)
P 		2036.9
(1.7)
P 		1461.2
(-0.8)
P 		1805.3
(0.7)
P 		957.5
(-3)
P 		1476
(-0.8)
P 		1386
C 1955.9
(3)
P 		1919
(2.8)
P 		1774.5
(1.8)
P 		1772.9
(1.8)
P 		1014.2
(-3)
P 		1331.3
(-1)
P 		942
avr 2322.7
(3) 		1940.4
(1.1) 		1464.1
(-1.2) 		1607.6
(-0.5) 		1109.6
(-3) 		1426.7
(-1.4) 		1213
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 604
1 2 3 4 range
A 735
(3)
P 		295.3
(-1.4)
P 		314.9
(-1.2)
P 		131
(-3)
P 		604
B 664.3
(3)
P 		296.3
(-1.6)
P 		285
(-1.7)
P 		181
(-3)
P 		483
C 636.3
(3)
P 		363.9
(-0.2)
P 		354.6
(-0.3)
P 		131.1
(-3)
P 		505
avr 678.5
(3) 		318.5
(-1.1) 		318.2
(-1.1) 		147.7
(-3) 		531

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 563
1 2 3 4 5 6 range
A 492
(0.5)
P 		663.3
(3)
P 		251.9
(-3)
P 		315.6
(-2.1)
P 		409.5
(-0.7)
P 		358.6
(-1.4)
P 		411
B 815.3
(3)
P 		678
(1.2)
P 		354.8
(-3)
P 		478.2
(-1.4)
P 		389
(-2.6)
P 		550.4
(-0.5)
P 		461
C 725
(3)
P 		585.6
(0.9)
P 		451.6
(-1.1)
P 		356.5
(-2.6)
P 		328.2
(-3)
P 		445.7
(-1.2)
P 		397
avr 677.4
(3) 		642.3
(2.4) 		352.8
(-3) 		383.4
(-2.4) 		375.6
(-2.6) 		451.6
(-1.2) 		325
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189907_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1010
Sequence Type Exemplar sequence
Representative Public ID T21E12.4 NCBI
Target Description T21E12.4 /REP_DB=WormBase Gene ID /WP=CE23997 /GEN=dhc-1 /GB=AAK21472.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=dynein heavy chain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058962(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058962 NCBI Caenorhabditis elegans Dynein Heavy Chain family member (dhc-1) (dhc-1) mRNA, complete cds. 11/11 None
SNAP00000041455 ENSEMBL cdna:SNAP chromosome:CEL140:I:4386788:4401756:1 11/11 None
GENEFINDER00000041462 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:4386791:4401756:1 11/11 None
T21E12.4 ENSEMBL cdna:known chromosome:CEL140:I:4386791:4401981:1 gene:T21E12.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:4386790-4401756(+) 100.0 100.0
Public Domain and Genome References
Gene Title dynein heavy chain
Gene Symbol dhc-1
Ensembl T21E12.4
Entrez Gene 172041 Entrez gene
SwissProt Q19020 EMBL-EBI
WormBase CE23997 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1583299_AT similar to dynein, cytoplasmic, heavy polypeptide 1 cfa
CANINE_2:CFA.1472.1.A1_AT similar to dynein, cytoplasmic, heavy polypeptide 1 cfa
CANINE_2:CFA.1472.1.A1_S_AT similar to dynein, cytoplasmic, heavy polypeptide 1 cfa
CANINE_2:CFA.17344.1.S1_S_AT similar to dynein, cytoplasmic, heavy polypeptide 1 cfa
CANINE_2:CFA.18098.1.S1_S_AT similar to dynein, cytoplasmic, heavy polypeptide 1 cfa
CANINE_2:CFA.20805.1.S1_S_AT similar to dynein, cytoplasmic, heavy polypeptide 1 cfa
DROSOPHILA_2:1623383_AT Dynein heavy chain 64C dm
DROSGENOME1:151529_AT Dynein heavy chain 64C dm
DROSOPHILA_2:1637137_A_AT Dynein heavy chain 64C dm
DROSOPHILA_2:1632408_AT Dynein heavy chain 64C dm
CHICKEN:GGA.2959.1.S1_AT similar to Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) gga
CHICKEN:GGA.2959.2.S1_AT similar to Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) gga
CHICKEN:GGAAFFX.23527.1.S1_S_AT similar to Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) gga
HG-U133_PLUS_2:211928_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133A_2:211928_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133A:211928_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133_PLUS_2:244768_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133B:244768_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBA:HUM_ALU_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBB:HUM_ALU_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBC:HUM_ALU_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBD:HUM_ALU_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HUGENEFL:HUM_ALU_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HC-G110:HUM_ALU_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBA:AB002323_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBB:RC_T86293_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133_PLUS_2:229115_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133B:229115_AT dynein, cytoplasmic, heavy polypeptide 1 hs
U133_X3P:HS.7720.3.A1_3P_AT dynein, cytoplasmic, heavy polypeptide 1 hs
U133_X3P:HS.7720.0.A1_3P_AT dynein, cytoplasmic, heavy polypeptide 1 hs
U133_X3P:HS.320699.0.A1_3P_AT dynein, cytoplasmic, heavy polypeptide 1 hs
U133_X3P:HS.309947.0.A1_3P_S_AT dynein, cytoplasmic, heavy polypeptide 1 hs
U133_X3P:HS.302653.0.S1_3P_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133_PLUS_2:236183_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133B:236183_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133_PLUS_2:241084_X_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133B:241084_X_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U95AV2:37300_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U95B:48151_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U95C:50084_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U95C:63979_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U95D:82861_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133_PLUS_2:229042_S_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133B:229042_S_AT dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U95B:47960_AT dynein, cytoplasmic, heavy polypeptide 1 hs
U133_X3P:HS2.376169.1.S1_3P_X_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
U133_X3P:HS2.376169.1.S1_3P_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
U133_X3P:1556831_3P_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133_PLUS_2:1556831_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U95D:74065_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133_PLUS_2:233925_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U133B:233925_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
HG-U95C:65376_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBA:N39708_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBB:RC_AA058843_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBC:RC_N46343_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
HU35KSUBD:RC_H97017_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
U133_X3P:HS.7720.2.S1_3P_AT Dynein, cytoplasmic, heavy polypeptide 1 hs
MU11KSUBB:MSA.5789.0_S_AT dynein, cytoplasmic, heavy chain 1 mm
MU11KSUBB:MSA.5688.0_S_AT dynein, cytoplasmic, heavy chain 1 mm
MU11KSUBB:MSA.33267.0_AT dynein, cytoplasmic, heavy chain 1 mm
MG-U74AV2:97333_AT dynein, cytoplasmic, heavy chain 1 mm
MOE430A:1416648_AT dynein, cytoplasmic, heavy chain 1 mm
MOUSE430A_2:1416648_AT dynein, cytoplasmic, heavy chain 1 mm
MOUSE430_2:1416648_AT dynein, cytoplasmic, heavy chain 1 mm
MOE430B:1439950_AT dynein, cytoplasmic, heavy chain 1 mm
MOUSE430_2:1439950_AT dynein, cytoplasmic, heavy chain 1 mm
MG-U74CV2:167954_AT Dynein, cytoplasmic, heavy chain 1, mRNA (cDNA clone IMAGE:3584121) mm
MU19KSUBB:TC29874_AT Dynein, cytoplasmic, heavy chain 1, mRNA (cDNA clone IMAGE:3584121) mm
MU19KSUBB:TC30838_AT Dynein, cytoplasmic, heavy chain 1, mRNA (cDNA clone IMAGE:3584121) mm
MU19KSUBC:TC38885_AT Dynein, cytoplasmic, heavy chain 1, mRNA (cDNA clone IMAGE:3584121) mm
RG-U34A:L08505_AT dynein, cytoplasmic, heavy chain 1 rn
RAE230A:1398803_AT dynein, cytoplasmic, heavy chain 1 rn
RAT230_2:1398803_AT dynein, cytoplasmic, heavy chain 1 rn
RG-U34B:RC_AA997606_AT Dynein, cytoplasmic, heavy chain 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
7018 microtubule-based movement inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
30286 dynein complex inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
166 nucleotide binding inferred from electronic annotation QuickGO AmiGO
3777 microtubule motor activity inferred from electronic annotation QuickGO AmiGO
4197 cysteine-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK21472 Dynein heavy chain protein 1 [Caenorhabditis elegans] ref|NP_491363.1| Dynein Heavy Chain family member (dhc-1) [Caenorhabditis elegans] sp|Q19020|DYHC_CAEEL Dynein heavy chain, cytosolic (DYHC) gb|AAC37251.1| dynein heavy chain 0.0
blast D87755 protein T21E12.4 [imported] - Caenorhabditis elegans 0.0
blast CAE66826 Hypothetical protein CBG12193 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
scop a.2.7.Methicillin resistance protein FemA probable tRNA-binding arm All alpha proteins; Long alpha-hairpin; tRNA-binding arm; Methicillin resistance protein FemA probable tRNA-binding arm 0.370000004768372
Pfam IPR004273 EMBL-EBI Dynein heavy chain 1.0E-126
Pfam IPR004273 EMBL-EBI Dynein heavy chain 1.0E-126
Pfam IPR004273 EMBL-EBI Dynein heavy chain 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:189907_S_AT
ttgaacgaaatttccgctgtctgccgagccgaaaagaaacaaaacaatgagacacgtgca
ctggctgccagtctacagaagggagaagttccaacaggatggaagagatacactgttcca
cgagaagttactgtgatggattggatgactgatctcaacgaacgactgaaacaactgatt
cgtatcggaggagctgataacttgaagcgtgaaactttctggcttggaggaactttctca
ccagaagcctacatcactgccactcgccaacaagttgctcaggccaacacttggtctctc
gaacagctcaatcttcacattcacattggacgaactgatagtacagatgtgttccgtatt
tcgggaattgatattcgtggagcaaaatcagtcggcggaaataaacttgaactgtgcgag
cttgtcaaatccgaatgtgacattgtcgagttcagttggaagcaggatgttgctgatgga
acacgtctgccactgtatctctatggtgatcgccgtcaactgatttcaccactcgcattc
catctttcttctgcaacagtgt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGAACGAAATTTCCGCTGTCTGCC 661 703 13114 Antisense
ACAATGAGACACGTGCACTGGCTGC 600 113 13157 Antisense
TCACCAGAAGCCTACATCACTGCCA 640 625 13351 Antisense
TGCCACTCGCCAACAAGTTGCTCAG 347 587 13371 Antisense
TCAGGCCAACACTTGGTCTCTCGAA 111 623 13392 Antisense
ACAGCTCAATCTTCACATTCACATT 141 109 13416 Antisense
GAACTGTGCGAGCTTGTCAAATCCG 151 349 13522 Antisense
GTTGCTGATGGAACACGTCTGCCAC 310 439 13582 Antisense
GTCTGCCACTGTATCTCTATGGTGA 495 471 13598 Antisense
TCTATGGTGATCGCCGTCAACTGAT 384 615 13613 Antisense
TTCCATCTTTCTTCTGCAACAGTGT 246 701 13651 Antisense
Sequence Source Affymetrix Proprietary Database