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[189894_at] DNA-binding protein

Description C42D8.4 /REP_DB=WormBase Gene ID /WP=CE04205 /TR=Q18579 /GB=AAA98717.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=DNA-binding protein
Cluster 6grp_total > 04      4grp_total > 21      6grp_cgc > 32      6grp_cgc_sub > De      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 166
1 2 3 4 range
A 155.5
(2.3)
A 		22.8
(-2.8)
A 		18.8
(-3)
A 		172.3
(3)
A 		154
B 168.6
(3)
M 		87.3
(-0)
A 		6.6
(-3)
A 		147.1
(2.2)
P 		162
C 128.7
(1.4)
A 		96.7
(0.1)
A 		19
(-3)
A 		169.7
(3)
P 		151
avr 150.9
(2.5) 		68.9
(-0.8) 		14.8
(-3) 		163
(3) 		148

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 147
1 2 3 4 5 6 range
A 127.8
(3)
A 		71
(0)
A 		74.1
(0.2)
A 		58.8
(-0.6)
A 		13
(-3)
A 		13.8
(-3)
A 		115
B 127.3
(2.1)
A 		148.7
(3)
A 		77.5
(0.1)
A 		80
(0.2)
A 		30.8
(-1.8)
A 		2
(-3)
A 		147
C 127.8
(3)
A 		125
(2.9)
A 		12.6
(-2.8)
A 		11.2
(-2.9)
A 		66.2
(-0.1)
A 		8.5
(-3)
A 		119
avr 127.6
(3) 		114.9
(2.4) 		54.7
(-0.7) 		50
(-0.9) 		36.7
(-1.6) 		8.1
(-3) 		120
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 55
1 2 3 4 range
A 56.6
(3)
A 		4.9
(-3)
A 		4.9
(-3)
A 		25.2
(-0.6)
A 		52
B 53.8
(3)
M 		21.6
(-0.7)
A 		1.5
(-3)
A 		31.3
(0.4)
P 		52
C 42.6
(3)
A 		27.8
(0.5)
A 		6.6
(-3)
A 		28.6
(0.7)
P 		36
avr 51
(3) 		18.1
(-1.2) 		4.3
(-3) 		28.4
(0.1) 		47

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 49
1 2 3 4 5 6 range
A 23.6
(2.5)
A 		25.3
(3)
A 		16.1
(0.5)
A 		14.9
(0.2)
A 		3.9
(-2.8)
A 		3.3
(-3)
A 		22
B 44.3
(2.4)
A 		49.5
(3)
A 		18.8
(-0.8)
A 		21.2
(-0.5)
A 		12.5
(-1.6)
A 		0.8
(-3)
A 		49
C 47.4
(3)
A 		38.2
(1.8)
A 		3.2
(-2.9)
A 		2.2
(-3)
A 		21.4
(-0.5)
A 		2.8
(-2.9)
A 		45
avr 38.4
(3) 		37.7
(2.9) 		12.7
(-1.3) 		12.8
(-1.3) 		12.6
(-1.3) 		2.3
(-3) 		36
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189894_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16177
Sequence Type Exemplar sequence
Representative Public ID C42D8.4 NCBI
Target Description C42D8.4 /REP_DB=WormBase Gene ID /WP=CE04205 /TR=Q18579 /GB=AAA98717.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=DNA-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076464(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076464 NCBI Caenorhabditis elegans C42D8.4 (C42D8.4) mRNA, complete cds. 11/11 None
SNAP00000033874 ENSEMBL cdna:SNAP chromosome:CEL140:X:5079729:5082836:-1 11/11 None
GENEFINDER00000033886 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:5079746:5084246:-1 11/11 None
C42D8.4 ENSEMBL cdna:known chromosome:CEL140:X:5079746:5081590:-1 gene:C42D8.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:5079746-5081591(-) 100.0 100.0
Public Domain and Genome References
Gene Title DNA-binding protein
Gene Symbol ets-5
Ensembl C42D8.4
Entrez Gene 180778 Entrez gene
SwissProt Q18579 EMBL-EBI
WormBase CE04205 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSGENOME1:151313_AT Ets at 65A dm
DROSOPHILA_2:1640371_A_AT Ets at 65A dm
DROSGENOME1:152728_AT Ets at 65A dm
DROSGENOME1:148266_AT Ets at 65A dm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_508865 C42D8.4 [Caenorhabditis elegans] gb|AAA98717.1| Hypothetical protein C42D8.4 [Caenorhabditis elegans] 1.0E-105
blast CAE68690 Hypothetical protein CBG14604 [Caenorhabditis briggsae] 1.0E-85
blast CAE68690 Hypothetical protein CBG14604 [Caenorhabditis briggsae] 2.0E-85
blast NP_508865 C42D8.4 [Caenorhabditis elegans] gb|AAA98717.1| Hypothetical protein C42D8.4 [Caenorhabditis elegans] 1.0E-82
blast CAE68690 Hypothetical protein CBG14604 [Caenorhabditis briggsae] 6.0E-70
blast AAF50696 CG7018-PB, isoform B [Drosophila melanogaster] ref|NP_523945.2| CG7018-PB, isoform B [Drosophila melanogaster] gb|AAL25355.1| GH18452p [Drosophila melanogaster] 6.0E-46
blast AAF50696 CG7018-PB, isoform B [Drosophila melanogaster] ref|NP_523945.2| CG7018-PB, isoform B [Drosophila melanogaster] gb|AAL25355.1| GH18452p [Drosophila melanogaster] 1.0E-45
Protein Domains
Database ID Description E-Value
Pfam IPR000418 EMBL-EBI Ets-domain 1.1E-61
Pfam IPR000418 EMBL-EBI Ets-domain 1.1E-61
Pfam IPR000418 EMBL-EBI Ets-domain 1.1E-61
Sequence
Target Sequence 
>C. ELEGANS:189894_AT
tgcaatacgcgagtgctctttcacgaattccatcatccaacagcacgagtgcatccaaag
gtcctatggcgattgcattatcagcaactgggactggtcaaattcaactgtggcagtttt
tgttggagcttctcgctgacgccgtcaatgcacactgcattgcttgggaaggtagcaacg
gggagttcaaattggttgacccagacgaggtcgccaggaaatggggagagcggaagagta
agccgaatatgaactacgataagttgagcagagcactccggtattattatgacaagaata
ttatgacaaaggtacaaggaaagcgttacgcgtataagttcgatttccaaggacttgctc
aagcttgtcagagtgcaattttgacaaatggtggaaaccccaacggagatctgtcatcaa
ctgttcattcactatcaccatacacaaatcaagtgcttccaattggtgtgaccagccgat
tatcgacttcaatgtcttcatatcattcaatactttcctcaacttcgtctacctcttcca
atcagataattccaccatcgactgcgacatactggtcgactcct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGCAATACGCGAGTGCTCTTTCACG 168 577 14 Antisense
TCTTTCACGAATTCCATCATCCAAC 587 615 30 Antisense
GCACGAGTGCATCCAAAGGTCCTAT 641 313 56 Antisense
GTTTTTGTTGGAGCTTCTCGCTGAC 478 449 129 Antisense
TCTCGCTGACGCCGTCAATGCACAC 200 611 144 Antisense
TGGTTGACCCAGACGAGGTCGCCAG 535 545 206 Antisense
GGAAACCCCAACGGAGATCTGTCAT 352 527 406 Antisense
AACTGTTCATTCACTATCACCATAC 219 143 432 Antisense
TGGTGTGACCAGCCGATTATCGACT 318 553 477 Antisense
CGTCTACCTCTTCCAATCAGATAAT 23 247 539 Antisense
GACTGCGACATACTGGTCGACTCCT 266 375 573 Antisense
Sequence Source Affymetrix Proprietary Database