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[189876_at] UMP-CMP kinase like

Description F40F8.1 /REP_DB=WormBase Gene ID /WP=CE05842 /TR=Q20230 /GB=CAA93264.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=UMP-CMP kinase like
Cluster 6grp_highest_10_10 > 37      6grp_high1_10_10 > 73      4grp_highest_8_8 > 12      4grp_high_8_8 > 39      6grp_highest_nonorm > 55      6grp_total > 74      4grp_total > 41      6grp_highest_sub > 03_04      6grp_high1_sub > 03_04      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 493
1 2 3 4 range
A 991.8
(-3)
P 		1380.8
(3)
P 		1269.5
(1.3)
P 		1152.8
(-0.5)
P 		389
B 957.3
(-3)
P 		1202.5
(-0)
P 		1450.5
(3)
P 		1238.7
(0.4)
P 		493
C 994.8
(-3)
P 		1239.8
(2.3)
P 		1268.4
(2.9)
P 		1271.8
(3)
P 		277
avr 981.3
(-3) 		1274.4
(2.1) 		1329.5
(3) 		1221.1
(1.1) 		348

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1416
1 2 3 4 5 6 range
A 821.6
(-3)
P 		1259.8
(-1)
P 		1821.8
(1.5)
P 		2141.1
(3)
P 		1172.2
(-1.4)
P 		1527.1
(0.2)
P 		1320
B 913.8
(-3)
P 		1093.3
(-1.6)
P 		1699.3
(3)
P 		1463.7
(1.2)
P 		1376.5
(0.5)
P 		1370.1
(0.5)
P 		786
C 973.3
(-3)
P 		979.7
(-3)
P 		2013.4
(1.9)
P 		2237.2
(3)
P 		1579.9
(-0.1)
P 		1558.7
(-0.2)
P 		1264
avr 902.9
(-3) 		1110.9
(-1.8) 		1844.8
(2.4) 		1947.3
(3) 		1376.2
(-0.3) 		1485.3
(0.3) 		1044
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 273
1 2 3 4 range
A 361.1
(3)
P 		299.7
(1.1)
P 		331.9
(2.1)
P 		168.7
(-3)
P 		192
B 305.3
(0.4)
P 		297
(-0.3)
P 		336.1
(3)
P 		264
(-3)
P 		72
C 329.3
(0)
P 		356.4
(0.7)
P 		442.1
(3)
P 		214.4
(-3)
P 		228
avr 331.9
(1.5) 		317.7
(1) 		370
(3) 		215.7
(-3) 		154

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 408
1 2 3 4 5 6 range
A 151.5
(-3)
P 		448
(1.5)
P 		396.7
(0.8)
P 		543
(3)
P 		353.7
(0.1)
P 		371.8
(0.4)
P 		392
B 318
(-3)
P 		363.9
(-1.9)
P 		412.6
(-0.6)
P 		387.7
(-1.3)
P 		559.2
(3)
P 		510.9
(1.8)
P 		241
C 360.8
(-1.3)
P 		298.9
(-3)
P 		512.4
(2.7)
P 		449.9
(1.1)
P 		511.2
(2.7)
P 		521.8
(3)
P 		223
avr 276.8
(-3) 		370.3
(-0.2) 		440.6
(2) 		460.2
(2.6) 		474.7
(3) 		468.2
(2.8) 		198
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189876_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3208
Sequence Type Exemplar sequence
Representative Public ID F40F8.1 NCBI
Target Description F40F8.1 /REP_DB=WormBase Gene ID /WP=CE05842 /TR=Q20230 /GB=CAA93264.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=UMP-CMP kinase like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063985(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063985 NCBI Caenorhabditis elegans F40F8.1 (F40F8.1) mRNA, complete cds. 11/11 None
SNAP00000001350 ENSEMBL cdna:SNAP chromosome:CEL140:II:11128401:11129027:1 11/11 None
GENEFINDER00000001365 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:11127682:11129027:1 11/11 None
F40F8.1.1 ENSEMBL cdna:known chromosome:CEL140:II:11127558:11129157:1 gene:F40F8.1 11/11 None
F40F8.1.2 ENSEMBL cdna:known chromosome:CEL140:II:11127623:11129157:1 gene:F40F8.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:11128397-11129024(+) 100.0 100.0
Public Domain and Genome References
Gene Title UMP-CMP kinase like
Ensembl F40F8.1
Entrez Gene 174701 Entrez gene
SwissProt Q20230 EMBL-EBI
WormBase CE05842 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.2567.2.S1_AT similar to UMP-CMP kinase (Cytidylate kinase) (Deoxycytidylate kinase) (Cytidine monophosphate kinase) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) (Uridine monophosphate kinase) cfa
CANINE_2:CFA.2567.2.S1_S_AT similar to UMP-CMP kinase (Cytidylate kinase) (Deoxycytidylate kinase) (Cytidine monophosphate kinase) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) (Uridine monophosphate kinase) cfa
DROSOPHILA_2:1636539_AT dm
DROSGENOME1:141217_AT dm
CHICKEN:GGAAFFX.12240.1.S1_S_AT cytidylate kinase gga
HG-U133B:222448_S_AT cytidylate kinase hs
HG-U133_PLUS_2:222448_S_AT cytidylate kinase hs
HG-U133_PLUS_2:217870_S_AT cytidylate kinase hs
HG-U133A:217870_S_AT cytidylate kinase hs
HG-FOCUS:217870_S_AT cytidylate kinase hs
HG-U133A_2:217870_S_AT cytidylate kinase hs
HU35KSUBA:RC_AA159322_AT cytidylate kinase hs
HU35KSUBA:R67751_AT cytidylate kinase hs
HU35KSUBA:AA458603_AT cytidylate kinase hs
U133_X3P:G7706496_3P_S_AT cytidylate kinase hs
U133_X3P:G6563219_3P_A_AT cytidylate kinase hs
U133_X3P:HS2.382940.1.S1_3P_AT cytidylate kinase hs
HG-U133_PLUS_2:1570533_AT cytidylate kinase hs
HG-U95B:56498_AT cytidylate kinase hs
HU35KSUBA:L44424_AT Cytidylate kinase hs
MOUSE430_2:1423073_AT cytidylate kinase mm
MOE430A:1423073_AT cytidylate kinase mm
MOUSE430A_2:1423073_AT cytidylate kinase mm
MU11KSUBA:AA543970_AT cytidylate kinase mm
MU11KSUBB:MSA.33790.0_AT cytidylate kinase mm
MG-U74AV2:160356_AT cytidylate kinase mm
MG-U74CV2:140830_AT Cytidylate kinase, mRNA (cDNA clone MGC:18911 IMAGE:4241782) mm
MOE430B:1440308_AT Cytidylate kinase, mRNA (cDNA clone MGC:18911 IMAGE:4241782) mm
MOUSE430_2:1440308_AT Cytidylate kinase, mRNA (cDNA clone MGC:18911 IMAGE:4241782) mm
MU19KSUBC:TC37775_AT Cytidylate kinase, mRNA (cDNA clone MGC:18911 IMAGE:4241782) mm
RG-U34B:RC_AA945089_AT similar to UMP-CMP kinase (predicted) rn
RAE230A:1373365_AT similar to UMP-CMP kinase (predicted) rn
RAT230_2:1373365_AT similar to UMP-CMP kinase (predicted) rn
YEAST_2:1773307_AT Uridylate kinase, catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP) Sc
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
16776 phosphotransferase activity, phosphate group as acceptor inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93264 Hypothetical protein F40F8.1 [Caenorhabditis elegans] ref|NP_496386.1| F40F8.1 [Caenorhabditis elegans] 1.0E-107
blast CAE59564 Hypothetical protein CBG02961 [Caenorhabditis briggsae] 2.0E-93
blast CAE59564 Hypothetical protein CBG02961 [Caenorhabditis briggsae] 3.0E-93
Protein Domains
Database ID Description E-Value
Pfam IPR000850 EMBL-EBI Adenylate kinase 2.0E-54
Pfam IPR000850 EMBL-EBI Adenylate kinase 2.0E-54
Sequence
Target Sequence 
>C. ELEGANS:189876_AT
tttgaactacgtccacttatcagccggagatttgcttcgagcggaacgtcaaagagaagg
aagcgagttcggagctctcatcgaaagtcatatcaaaaatgggtcaatcgttcctgttga
gatcacctgttccctcctcgagaatgccatgaaagcttgtggagatgctaaaggcttcct
ggttgacggattcccgagaaacgaggataaccttcaaggatggaacaagcagatggatgg
taaagcactcgtccagttcgtgcttttcctttcgtgtcctgtttcgatttgcattgaaag
atgtctgaatcgtggccaagggagaaccgatgacaatgaggagtctttgaagaagcgtgt
cgagacctacaatcaacaaaccttcccaatcatcgagcactttgaaaaatccggactcgt
cagagaagtgaagagcgaacgtccggtggatgttgtg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTGAACTACGTCCACTTATCAGCC 573 667 87 Antisense
ATCAGCCGGAGATTTGCTTCGAGCG 332 29 105 Antisense
AGGAAGCGAGTTCGGAGCTCTCATC 469 55 144 Antisense
AATCGTTCCTGTTGAGATCACCTGT 393 169 192 Antisense
TCCCTCCTCGAGAATGCCATGAAAG 480 597 217 Antisense
CTTCCTGGTTGACGGATTCCCGAGA 609 217 261 Antisense
GGTAAAGCACTCGTCCAGTTCGTGC 58 503 325 Antisense
CGTGTCCTGTTTCGATTTGCATTGA 333 245 359 Antisense
GAGACCTACAATCAACAAACCTTCC 493 393 448 Antisense
CTTCCCAATCATCGAGCACTTTGAA 44 219 468 Antisense
GAGCGAACGTCCGGTGGATGTTGTG 156 385 519 Antisense
Sequence Source Affymetrix Proprietary Database