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[189870_at] trypsin inhibitor

Description Y49G5A.1 /REP_DB=WormBase Gene ID /WP=CE22273 /TR=Q9UAZ2 /GB=AAD14760.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=trypsin inhibitor
Cluster 6grp_total > 21      4grp_total > 41      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 76
1 2 3 4 range
A 18.7
(-3)
A 		34.7
(0.2)
A 		48.3
(3)
P 		46.5
(2.6)
A 		30
B 1.3
(-3)
A 		62.6
(3)
A 		54.9
(2.2)
A 		1.2
(-3)
A 		61
C 42.4
(-2.4)
A 		77.5
(3)
A 		38.6
(-3)
A 		68.8
(1.7)
A 		39
avr 20.8
(-3) 		58.3
(3) 		47.3
(1.2) 		38.8
(-0.1) 		38

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 98
1 2 3 4 5 6 range
A 54
(1.2)
A 		70.2
(2.6)
M 		74.3
(3)
M 		65.9
(2.2)
P 		71.3
(2.7)
P 		7.4
(-3)
A 		67
B 27.8
(-1.4)
A 		73.7
(3)
P 		44.5
(0.2)
P 		59.4
(1.6)
A 		49.6
(0.7)
M 		10.8
(-3)
A 		63
C 34.4
(-0.9)
A 		98.4
(3)
P 		43.5
(-0.4)
P 		64.5
(0.9)
M 		46
(-0.2)
A 		0.7
(-3)
A 		98
avr 38.7
(-0.4) 		80.8
(3) 		54.1
(0.8) 		63.3
(1.6) 		55.6
(1) 		6.3
(-3) 		75
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 22
1 2 3 4 range
A 6.8
(-3)
A 		7.5
(-2.3)
A 		12.6
(3)
P 		6.8
(-3)
A 		6
B 0.4
(-3)
A 		15.5
(3)
A 		12.7
(1.9)
A 		0.3
(-3)
A 		15
C 14
(-1.7)
A 		22.3
(3)
A 		13.5
(-1.9)
A 		11.6
(-3)
A 		11
avr 7.1
(-2.4) 		15.1
(3) 		12.9
(1.5) 		6.2
(-3) 		9

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 30
1 2 3 4 5 6 range
A 10
(-0.9)
A 		25
(3)
M 		16.2
(0.7)
M 		16.7
(0.9)
P 		21.5
(2.1)
P 		1.8
(-3)
A 		23
B 9.7
(-1.3)
A 		24.5
(3)
P 		10.8
(-1)
P 		15.7
(0.4)
A 		20.2
(1.7)
M 		4
(-3)
A 		21
C 12.8
(-0.5)
A 		30
(3)
P 		11.1
(-0.8)
P 		13
(-0.4)
M 		14.9
(-0)
A 		0.2
(-3)
A 		30
avr 10.8
(-0.8) 		26.5
(3) 		12.7
(-0.4) 		15.1
(0.2) 		18.9
(1.1) 		2
(-3) 		25
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189870_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11850
Sequence Type Exemplar sequence
Representative Public ID Y49G5A.1 NCBI
Target Description Y49G5A.1 /REP_DB=WormBase Gene ID /WP=CE22273 /TR=Q9UAZ2 /GB=AAD14760.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=trypsin inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072012(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072012 NCBI Caenorhabditis elegans Y49G5A.1 (Y49G5A.1) mRNA, complete cds. 11/11 None
SNAP00000021354 ENSEMBL cdna:SNAP chromosome:CEL140:V:5286219:5287172:-1 11/11 None
GENEFINDER00000021356 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:5286219:5287172:-1 11/11 None
Y49G5A.1 ENSEMBL cdna:known chromosome:CEL140:V:5286219:5287172:-1 gene:Y49G5A.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:5286218-5287172(-) 100.0 100.0
Public Domain and Genome References
Gene Title trypsin inhibitor
Ensembl Y49G5A.1
Entrez Gene 190090 Entrez gene
SwissProt Q9UAZ2 EMBL-EBI
WormBase CE22273 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAD14760 Hypothetical protein Y49G5A.1 [Caenorhabditis elegans] ref|NP_504413.1| Y49G5A.1 [Caenorhabditis elegans] 1.0E-109
blast CAE62639 Hypothetical protein CBG06772 [Caenorhabditis briggsae] 4.0E-66
blast CAE62640 Hypothetical protein CBG06774 [Caenorhabditis briggsae] 2.0E-57
Protein Domains
Database ID Description E-Value
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 4.8E-19
Sequence
Target Sequence 
>C. ELEGANS:189870_AT
ttcttcttacctttttggctactattctgtgtgtcagtgagttagtctcgacacttcaac
cggagtgcaaacttccattggacatgggaaaaacaccatgtaaaaatggaaagaaggaga
taagataccactttgaccaaaaatccaatatcccattggcttttgagtacagtggatgtg
gaggaaacaagaataatttcaaaactgagagtgaatgtcgatttacatgtactggatatg
atcaatcgggatgtgccgctggaagtaagccaataaacgataaaaactgccaaaccgatg
aagaatgtgggccaaaaggtatctgtaggtactctaatcatattaatatttgctgtgaca
agaagattgaaaagttgattgaagctgattatgagccaaaatgtccaaaaggaaagaaag
ttgcaaaaattgtcgagggtggaatccctacaacgattgttgggaagagttgcaaatcaa
agttctgtccagctggagcaacctgtgtgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCTTCTTACCTTTTTGGCTACTAT 39 691 20 Antisense
TTTTGGCTACTATTCTGTGTGTCAG 455 677 32 Antisense
TGTGTGTCAGTGAGTTAGTCTCGAC 594 555 47 Antisense
TTAGTCTCGACACTTCAACCGGAGT 577 681 61 Antisense
ACCGGAGTGCAAACTTCCATTGGAC 395 87 78 Antisense
GGAGATAAGATACCACTTTGACCAA 697 517 135 Antisense
AAATCCAATATCCCATTGGCTTTTG 216 119 160 Antisense
GATCAATCGGGATGTGCCGCTGGAA 635 421 259 Antisense
GGTATCTGTAGGTACTCTAATCATA 383 505 337 Antisense
GGGTGGAATCCCTACAACGATTGTT 690 497 456 Antisense
TGTCCAGCTGGAGCAACCTGTGTGG 709 553 505 Antisense
Sequence Source Affymetrix Proprietary Database