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[189849_at] Cysteine protease

Description Y40H7A.10 /REP_DB=WormBase Gene ID /WP=CE21821 /TR=Q9XWA4 /GB=CAA22062.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Cysteine protease
Cluster 6grp_highest_10_10 > 48      6grp_high1_10_10 > 83      6grp_highest_nonorm > 63      6grp_total > 73      4grp_total > 59      6grp_high1_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S5      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 311
1 2 3 4 range
A 215.5
(0.3)
P 		312.8
(2.4)
P 		339.3
(3)
P 		61.5
(-3)
A 		278
B 233.3
(1)
P 		332.6
(3)
P 		318.2
(2.7)
P 		40
(-3)
A 		293
C 290.5
(1.8)
P 		234.7
(0.7)
P 		351
(3)
P 		45.5
(-3)
A 		306
avr 246.4
(1.1) 		293.4
(2.1) 		336.2
(3) 		49
(-3) 		287

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 665
1 2 3 4 5 6 range
A 182.2
(-3)
P 		366.5
(-1.1)
P 		700.4
(2.4)
P 		756.6
(3)
P 		705.6
(2.5)
P 		648.6
(1.9)
P 		574
B 122.2
(-3)
P 		329.8
(-1.1)
P 		683.2
(2.1)
P 		618.8
(1.5)
P 		787.5
(3)
P 		549.8
(0.9)
P 		665
C 154.9
(-3)
P 		318
(-1.2)
P 		607.3
(2.1)
P 		687.7
(3)
P 		662.5
(2.7)
P 		572
(1.7)
P 		533
avr 153.1
(-3) 		338.1
(-1) 		663.6
(2.4) 		687.7
(2.7) 		718.5
(3) 		590.1
(1.6) 		565
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 115
1 2 3 4 range
A 78.4
(2.2)
P 		67.9
(1.4)
P 		88.7
(3)
P 		9
(-3)
A 		80
B 74.4
(2.4)
P 		82.1
(3)
P 		73.7
(2.3)
P 		8.5
(-3)
A 		74
C 96.2
(1.6)
P 		67.5
(0.1)
P 		122.3
(3)
P 		7.7
(-3)
A 		115
avr 83
(2.2) 		72.5
(1.4) 		94.9
(3) 		8.4
(-3) 		87

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 286
1 2 3 4 5 6 range
A 33.6
(-3)
P 		130.3
(0.2)
P 		152.5
(1)
P 		191.9
(2.3)
P 		212.9
(3)
P 		157.9
(1.2)
P 		179
B 42.5
(-3)
P 		109.8
(-1.5)
P 		165.9
(-0.3)
P 		163.9
(-0.4)
P 		320
(3)
P 		205
(0.5)
P 		278
C 57.4
(-3)
P 		97
(-1.5)
P 		154.6
(0.7)
P 		138.3
(0.1)
P 		214.4
(3)
P 		191.5
(2.1)
P 		157
avr 44.5
(-3) 		112.4
(-1) 		157.7
(0.3) 		164.7
(0.5) 		249.1
(3) 		184.8
(1.1) 		205
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189849_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9429
Sequence Type Exemplar sequence
Representative Public ID Y40H7A.10 NCBI
Target Description Y40H7A.10 /REP_DB=WormBase Gene ID /WP=CE21821 /TR=Q9XWA4 /GB=CAA22062.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Cysteine protease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070435(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070435 NCBI Caenorhabditis elegans Y40H7A.10 (Y40H7A.10) mRNA, complete cds. 11/11 None
SNAP00000019409 ENSEMBL cdna:SNAP chromosome:CEL140:IV:15210134:15213684:-1 11/11 None
GENEFINDER00000019415 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:15210134:15215547:-1 11/11 None
Y40H7A.10 ENSEMBL cdna:known chromosome:CEL140:IV:15210134:15215558:-1 gene:Y40H7A.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:15210139-15215553(-) 100.0 100.0
Public Domain and Genome References
Gene Title Cysteine protease
Ensembl Y40H7A.10
Entrez Gene 189809 Entrez gene
SwissProt Q9XWA4 EMBL-EBI
WormBase CE21821 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4197 cysteine-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
8234 cysteine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA22062 Hypothetical protein Y40H7A.10 [Caenorhabditis elegans] ref|NP_502836.1| Y40H7A.10 [Caenorhabditis elegans] 0.0
blast CAE68098 Hypothetical protein CBG13738 [Caenorhabditis briggsae] 1.0E-151
blast CAA22062 Hypothetical protein Y40H7A.10 [Caenorhabditis elegans] ref|NP_502836.1| Y40H7A.10 [Caenorhabditis elegans] 1.0E-147
blast CAE68098 Hypothetical protein CBG13738 [Caenorhabditis briggsae] 1.0E-120
blast BAA22546.1 FB1035 precursor [Ananas comosus] 3.0E-38
Protein Domains
Database ID Description E-Value
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 1.4E-58
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 1.4E-58
Sequence
Target Sequence 
>C. ELEGANS:189849_AT
gttgggcatttgcaacagctgctgcaattgaatcggccgtatcaattagtggtggaggtc
tgcagagtttgtcttctcaacagctcctagactgcactgttgtatctgacaaatgtggag
gtggtgagccagttgaagctctcaaatatgctcaatcccatggaattaccactgctcata
actatccatactacttttggactacaaaatgtcgtgaaactgtaccaactgttgctcgaa
tctctagttggatgaaagcagaaagtgaagatgaaatggctcaaatagttgctctgaatg
gtccaatga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTGGGCATTTGCAACAGCTGCTGC 202 435 497 Antisense
GAATCGGCCGTATCAATTAGTGGTG 278 323 526 Antisense
GGAGGTCTGCAGAGTTTGTCTTCTC 116 517 550 Antisense
TTGTCTTCTCAACAGCTCCTAGACT 423 707 565 Antisense
GCTCCTAGACTGCACTGTTGTATCT 12 299 579 Antisense
GAAGCTCTCAAATATGCTCAATCCC 211 343 631 Antisense
CAATCCCATGGAATTACCACTGCTC 133 181 649 Antisense
ACCACTGCTCATAACTATCCATACT 527 85 664 Antisense
AATGTCGTGAAACTGTACCAACTGT 127 163 704 Antisense
TACCAACTGTTGCTCGAATCTCTAG 152 651 719 Antisense
ATAGTTGCTCTGAATGGTCCAATGA 672 21 781 Antisense
Sequence Source Affymetrix Proprietary Database