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[189834_at] GTP-binding protein

Description M01E5.2 /REP_DB=WormBase Gene ID /WP=CE12276 /TR=O45691 /GB=CAB07637.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=GTP-binding protein
Cluster 6grp_highest_10_10 > 66      6grp_high1_10_10 > 76      6grp_highest_nonorm > 81      6grp_total > 67      4grp_total > 43      6grp_highest_sub > Da      6grp_high1_sub > Da      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 206
1 2 3 4 range
A 252.2
(0.1)
P 		249.2
(-0.3)
M 		274
(3)
P 		228.8
(-3)
A 		45
B 247
(-3)
P 		422.9
(3)
A 		255.8
(-2.7)
A 		286.9
(-1.6)
P 		176
C 216.6
(-3)
P 		292.8
(3)
M 		232.4
(-1.8)
P 		278.1
(1.8)
M 		76
avr 238.6
(-3) 		321.6
(3) 		254.1
(-1.9) 		264.6
(-1.1) 		83

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 174
1 2 3 4 5 6 range
A 238.1
(-1.4)
P 		255.9
(-0.6)
P 		303.6
(1.8)
P 		206.5
(-3)
P 		270.8
(0.2)
P 		327.9
(3)
P 		121
B 269.1
(-1.6)
P 		259.1
(-2)
P 		282.3
(-1)
P 		235.8
(-3)
P 		243.5
(-2.7)
P 		377
(3)
P 		141
C 247.5
(-1.7)
P 		274.2
(-0.7)
P 		276.4
(-0.7)
P 		209.6
(-3)
P 		245.7
(-1.7)
P 		380.8
(3)
P 		171
avr 251.6
(-1.6) 		263.1
(-1.1) 		287.4
(-0.1) 		217.3
(-3) 		253.3
(-1.5) 		361.9
(3) 		145
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 71
1 2 3 4 range
A 91.8
(3)
P 		54.1
(-0.9)
M 		71.6
(0.9)
P 		33.5
(-3)
A 		58
B 78.8
(-0.4)
P 		104.4
(3)
A 		59.3
(-3)
A 		61.1
(-2.8)
P 		45
C 71.7
(1)
P 		84.2
(3)
M 		81
(2.5)
P 		46.9
(-3)
M 		37
avr 80.8
(3) 		80.9
(3) 		70.6
(1.2) 		47.2
(-3) 		34

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 99
1 2 3 4 5 6 range
A 43.9
(-3)
P 		91
(3)
P 		66.1
(-0.2)
P 		52.4
(-1.9)
P 		81.7
(1.8)
P 		79.8
(1.6)
P 		47
B 93.6
(-0.6)
P 		86.2
(-1.2)
P 		68.5
(-2.5)
P 		62.4
(-3)
P 		98.9
(-0.2)
P 		140.6
(3)
P 		78
C 91.7
(0.5)
P 		83.7
(-0.1)
P 		70.3
(-1)
P 		42.1
(-3)
P 		79.5
(-0.4)
P 		127.5
(3)
P 		85
avr 76.4
(-0.7) 		87
(0.3) 		68.3
(-1.5) 		52.3
(-3) 		86.7
(0.2) 		116
(3) 		64
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189834_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.662
Sequence Type Exemplar sequence
Representative Public ID M01E5.2 NCBI
Target Description M01E5.2 /REP_DB=WormBase Gene ID /WP=CE12276 /TR=O45691 /GB=CAB07637.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=GTP-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060933(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060933 NCBI Caenorhabditis elegans M01E5.2 (M01E5.2) mRNA, complete cds. 11/11 None
SNAP00000016098 ENSEMBL cdna:SNAP chromosome:CEL140:I:13285765:13288275:-1 11/11 None
GENEFINDER00000016136 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:13285765:13288275:-1 11/11 None
M01E5.2 ENSEMBL cdna:known chromosome:CEL140:I:13285180:13288294:-1 gene:M01E5.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:13285695-13288206(-) 100.0 100.0
Public Domain and Genome References
Gene Title GTP-binding protein
Ensembl M01E5.2
Entrez Gene 173192 Entrez gene
SwissProt O45691 EMBL-EBI
WormBase CE12276 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:249993_AT GTP1/OBG family protein at
CANINE:1601441_AT similar to GTP binding protein 5 cfa
CANINE:1594279_AT similar to GTP binding protein 5 cfa
CANINE:1588313_AT similar to GTP binding protein 5 cfa
CANINE_2:CFA.13706.1.A1_X_AT similar to GTP binding protein 5 cfa
CANINE_2:CFA.14720.1.A1_AT similar to GTP binding protein 5 cfa
CANINE_2:CFA.15019.1.A1_AT similar to GTP binding protein 5 cfa
CANINE_2:CFAAFFX.19500.1.S1_AT similar to GTP binding protein 5 cfa
DROSOPHILA_2:1624077_AT dm
DROSGENOME1:146026_AT dm
CHICKEN:GGAAFFX.3236.1.S1_AT similar to GTP binding protein 5; GTP-binding protein 5 (putative) gga
HU35KSUBD:RC_AA292376_AT GTP binding protein 5 (putative) hs
U133_X3P:HS2.425355.1.S1_3P_AT GTP binding protein 5 (putative) hs
U133_X3P:HS.35389.0.S1_3P_A_AT GTP binding protein 5 (putative) hs
U133_X3P:226598_3P_S_AT GTP binding protein 5 (putative) hs
HG-U133_PLUS_2:1568822_AT GTP binding protein 5 (putative) hs
HG-U133_PLUS_2:226598_S_AT GTP binding protein 5 (putative) hs
HG-U133B:226598_S_AT GTP binding protein 5 (putative) hs
HG-U133_PLUS_2:226606_S_AT GTP binding protein 5 (putative) hs
HG-U133B:226606_S_AT GTP binding protein 5 (putative) hs
HG-U95C:59491_AT GTP binding protein 5 (putative) hs
HG-U133_PLUS_2:236890_AT GTP binding protein 5 (putative) hs
HG-U133B:236890_AT GTP binding protein 5 (putative) hs
HG-U95E:71877_AT GTP binding protein 5 (putative) hs
U133_X3P:HS.221969.0.A1_3P_AT GTP binding protein 5 (putative) hs
MOUSE430A_2:1451467_S_AT GTP binding protein 5 mm
MOE430A:1451467_S_AT GTP binding protein 5 mm
MOUSE430_2:1451467_S_AT GTP binding protein 5 mm
MG-U74CV2:130778_AT GTP binding protein 5 mm
MOE430A:1452636_X_AT GTP binding protein 5 mm
MOUSE430A_2:1452636_X_AT GTP binding protein 5 mm
MOUSE430_2:1452636_X_AT GTP binding protein 5 mm
MOE430B:1460029_AT GTP binding protein 5 mm
MOUSE430_2:1460029_AT GTP binding protein 5 mm
MU19KSUBC:TC36075_AT GTP binding protein 5, mRNA (cDNA clone MGC:41265 IMAGE:1364804) mm
MU19KSUBC:TC36075_G_AT GTP binding protein 5, mRNA (cDNA clone MGC:41265 IMAGE:1364804) mm
MU19KSUBC:TC39377_AT GTP binding protein 5, mRNA (cDNA clone MGC:41265 IMAGE:1364804) mm
MU19KSUBC:TC39377_G_AT GTP binding protein 5, mRNA (cDNA clone MGC:41265 IMAGE:1364804) mm
RG-U34B:RC_AI012943_AT similar to GTP binding protein 5 rn
RAE230A:1373572_AT similar to GTP binding protein 5 rn
RAT230_2:1373572_AT similar to GTP binding protein 5 rn
YEAST_2:1777056_AT Putative GTPase, member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly Sc
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07637 Hypothetical protein M01E5.2 [Caenorhabditis elegans] ref|NP_493334.1| M01E5.2 [Caenorhabditis elegans] 0.0
blast XP_395391 PREDICTED: similar to CG13390-PA [Apis mellifera] 1.0E-74
blast AAH99033 Unknown (protein for MGC:115593) [Xenopus laevis] 7.0E-74
Protein Domains
Database ID Description E-Value
Pfam IPR006169 EMBL-EBI GTP1/OBG sub-domain 5.8E-50
Pfam IPR006169 EMBL-EBI GTP1/OBG sub-domain 9.2E-7
Pfam IPR006169 EMBL-EBI GTP1/OBG sub-domain 1.5E-36
Sequence
Target Sequence 
>C. ELEGANS:189834_AT
tatggcgacagcaggcctggttggattcccgaatgctggaaaatcttcgctgctccgtgc
aatttcccgagccaaaccgaaagtcgcctcgtacccatttacaacgctccacccgcatat
tggtgttgtattctatgaggatttcgagcaaatcgcggttgccgatattccagggctcat
tgaggattctcatttgaacaaagggctcggaatctcttttttgaagcatatcgaacgatg
cgaatccctgtggtacgtattggactattccactggatcactgacagatcaatacaaaat
gctccgcgttgaactggaaggatatcaaaaagggcttggagatcgagcatcaacaattgt
aatcaataagattgatttatcagggaagagcccggaggaagaagctcaccacctctcttc
actcttcccgaatctccctgtatttcctgtttctgcacaacaac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TATGGCGACAGCAGGCCTGGTTGGA 690 649 573 Antisense
CCTGGTTGGATTCCCGAATGCTGGA 98 267 588 Antisense
ATGCTGGAAAATCTTCGCTGCTCCG 248 43 605 Antisense
CGAGCCAAACCGAAAGTCGCCTCGT 630 249 640 Antisense
CGCTCCACCCGCATATTGGTGTTGT 524 255 677 Antisense
ATTTCGAGCAAATCGCGGTTGCCGA 660 15 713 Antisense
GTTGCCGATATTCCAGGGCTCATTG 74 441 730 Antisense
CGATGCGAATCCCTGTGGTACGTAT 288 249 808 Antisense
AATGCTCCGCGTTGAACTGGAAGGA 319 165 870 Antisense
AGGGCTTGGAGATCGAGCATCAACA 248 59 903 Antisense
GTATTTCCTGTTTCTGCACAACAAC 660 453 1012 Antisense
Sequence Source Affymetrix Proprietary Database