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[189823_s_at] dynein heavy chain

Description F18C12.1 /REP_DB=WormBase Gene ID /WP=CE05659 /TR=Q19542 /GB=CAA99830.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=dynein heavy chain
Cluster 6grp_high1_10_10 > 26      6grp_total > 26      4grp_total > 31      6grp_cgc > 15      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 315
1 2 3 4 range
A 352.6
(3)
P 		152.5
(-1.3)
A 		76.2
(-3)
A 		260.8
(1)
P 		276
B 375.2
(3)
P 		122.2
(-2.8)
A 		113.1
(-3)
A 		169.5
(-1.7)
P 		262
C 391.1
(3)
P 		137.1
(-2)
A 		83.3
(-3)
A 		210.3
(-0.5)
P 		308
avr 373
(3) 		137.3
(-2) 		90.9
(-3) 		213.5
(-0.4) 		282

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 184
1 2 3 4 5 6 range
A 253.5
(2.6)
P 		260
(3)
P 		160
(-3)
P 		176.9
(-2)
P 		162.8
(-2.8)
P 		168.8
(-2.5)
P 		100
B 298.3
(3)
P 		188.6
(-2.2)
P 		191.8
(-2)
P 		198.9
(-1.7)
P 		171.1
(-3)
P 		200.1
(-1.6)
P 		127
C 215.1
(0.8)
P 		272.5
(3)
P 		183
(-0.4)
P 		142.6
(-1.9)
P 		113.9
(-3)
M 		227.6
(1.3)
P 		159
avr 255.6
(3) 		240.4
(2.1) 		178.3
(-1.4) 		172.8
(-1.7) 		149.3
(-3) 		198.8
(-0.2) 		106
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 110
1 2 3 4 range
A 128.4
(3)
P 		33.1
(-2.3)
A 		19.9
(-3)
A 		38.2
(-2)
P 		109
B 119.6
(3)
P 		30.2
(-2.7)
A 		26.2
(-3)
A 		36.1
(-2.4)
P 		93
C 129.5
(3)
P 		39.4
(-2.4)
A 		29
(-3)
A 		35.5
(-2.6)
P 		101
avr 125.8
(3) 		34.2
(-2.5) 		25
(-3) 		36.6
(-2.3) 		101

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 75
1 2 3 4 5 6 range
A 46.7
(-1.8)
P 		92.5
(3)
P 		34.8
(-3)
P 		44.9
(-1.9)
P 		49.1
(-1.5)
P 		41.1
(-2.3)
P 		58
B 103.8
(3)
P 		62.8
(-1.3)
P 		46.6
(-3)
P 		52.7
(-2.4)
P 		69.5
(-0.6)
P 		74.6
(-0.1)
P 		57
C 79.7
(2.6)
P 		83.1
(3)
P 		46.6
(-1)
P 		28.7
(-3)
P 		36.9
(-2.1)
M 		76.2
(2.2)
P 		54
avr 76.7
(2.6) 		79.5
(3) 		42.7
(-2.9) 		42.1
(-3) 		51.8
(-1.4) 		64
(0.5) 		37
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189823_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2036
Sequence Type Exemplar sequence
Representative Public ID F18C12.1 NCBI
Target Description F18C12.1 /REP_DB=WormBase Gene ID /WP=CE05659 /TR=Q19542 /GB=CAA99830.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=dynein heavy chain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059820(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059820 NCBI Caenorhabditis elegans abnormal CHEmotaxis family member (che-3) (che-3) mRNA, complete cds. 11/11 None
SNAP00000022186 ENSEMBL cdna:SNAP chromosome:CEL140:I:8068969:8084823:-1 11/11 None
GENEFINDER00000022193 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:8068969:8089797:-1 11/11 None
F18C12.1 ENSEMBL cdna:known chromosome:CEL140:I:8070185:8089797:-1 gene:F18C12.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:8070115-8089728(-) 100.0 100.0
Public Domain and Genome References
Gene Title dynein heavy chain
Gene Symbol che-3
Ensembl F18C12.1
Entrez Gene 172593 Entrez gene
SwissProt Q19542 EMBL-EBI
WormBase CE32386 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1584134_S_AT similar to dynein, cytoplasmic, heavy polypeptide 2 cfa
CANINE:1584133_AT similar to dynein, cytoplasmic, heavy polypeptide 2 cfa
CANINE_2:CFA.4942.1.A1_S_AT similar to dynein, cytoplasmic, heavy polypeptide 2 cfa
CANINE_2:CFAAFFX.23098.1.S1_S_AT similar to dynein, cytoplasmic, heavy polypeptide 2 cfa
CHICKEN:GGAAFFX.11017.1.S1_S_AT similar to dynein, cytoplasmic, heavy chain 2 gga
CHICKEN:GGAAFFX.11017.3.S1_S_AT similar to dynein, cytoplasmic, heavy chain 2 gga
CHICKEN:GGAAFFX.11017.4.S1_S_AT similar to dynein, cytoplasmic, heavy chain 2 gga
CHICKEN:GGAAFFX.11017.5.S1_AT similar to dynein, cytoplasmic, heavy chain 2 gga
CHICKEN:GGAAFFX.11017.5.S1_S_AT similar to dynein, cytoplasmic, heavy chain 2 gga
HG-U133_PLUS_2:219469_AT dynein, cytoplasmic, heavy polypeptide 2 hs
HG-U133A:219469_AT dynein, cytoplasmic, heavy polypeptide 2 hs
HG-U133A_2:219469_AT dynein, cytoplasmic, heavy polypeptide 2 hs
HU35KSUBA:RC_AA609635_AT dynein, cytoplasmic, heavy polypeptide 2 hs
HUGENEFL:Z83800_AT dynein, cytoplasmic, heavy polypeptide 2 hs
U133_X3P:G13375812_3P_AT dynein, cytoplasmic, heavy polypeptide 2 hs
U133_X3P:HS2.384482.1.S1_3P_AT dynein, cytoplasmic, heavy polypeptide 2 hs
U133_X3P:HS2.383653.1.S1_3P_AT dynein, cytoplasmic, heavy polypeptide 2 hs
HG-U133_PLUS_2:1561939_AT dynein, cytoplasmic, heavy polypeptide 2 hs
HG-U133_PLUS_2:1565149_AT dynein, cytoplasmic, heavy polypeptide 2 hs
HG-U95B:44009_AT dynein, cytoplasmic, heavy polypeptide 2 hs
HG-U95D:71196_R_AT dynein, cytoplasmic, heavy polypeptide 2 hs
HG-U95C:58970_AT Dynein, cytoplasmic, heavy polypeptide 2 hs
MG-U74BV2:115507_AT dynein, cytoplasmic, heavy chain 2 mm
MG-U74BV2:105814_AT dynein, cytoplasmic, heavy chain 2 mm
MOE430B:1429250_AT dynein, cytoplasmic, heavy chain 2 mm
MOUSE430_2:1429250_AT dynein, cytoplasmic, heavy chain 2 mm
RG-U34A:D26495_AT hypothetical gene supported by NM_023024 rn
RAE230A:1368676_AT hypothetical gene supported by NM_023024 rn
RAT230_2:1368676_AT hypothetical gene supported by NM_023024 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7018 microtubule-based movement inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
30286 dynein complex inferred from electronic annotation QuickGO AmiGO
5929 cilium inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3777 microtubule motor activity inferred from electronic annotation QuickGO AmiGO
3777 microtubule motor activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA99830 Hypothetical protein F18C12.1 [Caenorhabditis elegans] ref|NP_492221.2| abnormal CHEmotaxis family member (che-3) [Caenorhabditis elegans] 0.0
blast CAE66545 Hypothetical protein CBG11853 [Caenorhabditis briggsae] 0.0
blast AAA63583 dynein heavy chain isotype 1B [Tripneustes gratilla] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR004273 EMBL-EBI Dynein heavy chain 1.0E-126
Pfam IPR004273 EMBL-EBI Dynein heavy chain 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000022186 1 3123-3145
GENEFINDER00000022193 1 4237-4259
Sequence
Target Sequence 
>C. ELEGANS:189823_S_AT
gcttctccagccgttcagaaaactattcaatcacttgtatttcaacagacacctgatgaa
tgggatagcatgtgggcgggaccaagtgatcctgcagattatttaaatgttgttgttaag
aagacacgtggaacattgcagctgttcgaatcgtcaaaatcatcttctctgctctcatcc
ccaattgatttttcggacttgttctatccaaacatctttttaaatgcactccgtcaaaca
acatctcgtcaaataaaaattccattagatcaactgatcttatcatcagcatggactcct
tctcaactaccagctaaacaatgtgttcaagttcaagggctcttgcttcaaggagcaacg
tttgattcatttcttcgtgaaactacagtatccagtgctgcttattctcaagctcctata
gtttttcttgcatggacatctgaaagttcttcaacgattactggagagcagattcaggta
ccagtgtatagttcaagtgaacgatctgatttgatatgctcggttaatatgccatgtcgt
ggagccgatcaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTTCTCCAGCCGTTCAGAAAACTA 510 305 11821 Antisense
ATGTGGGCGGGACCAAGTGATCCTG 484 49 11890 Antisense
ACATTGCAGCTGTTCGAATCGTCAA 303 103 11953 Antisense
CTCTCATCCCCAATTGATTTTTCGG 445 231 11992 Antisense
GATTTTTCGGACTTGTTCTATCCAA 451 429 12007 Antisense
AATGCACTCCGTCAAACAACATCTC 374 165 12043 Antisense
ATCATCAGCATGGACTCCTTCTCAA 178 31 12102 Antisense
TCCTTCTCAACTACCAGCTAAACAA 35 593 12117 Antisense
GTATCCAGTGCTGCTTATTCTCAAG 137 455 12208 Antisense
AGCTCCTATAGTTTTTCTTGCATGG 537 79 12231 Antisense
TATGCCATGTCGTGGAGCCGATCAA 608 657 12348 Antisense
Sequence Source Affymetrix Proprietary Database