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[189809_at] APX-1 like protein

Description F16B12.2 /REP_DB=WormBase Gene ID /WP=CE09426 /TR=Q93519 /GB=CAB02963.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=APX-1 like protein
Cluster 6grp_total > 44      4grp_total > 18      6grp_cgc > 90      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 108
1 2 3 4 range
A 5.9
(-3)
A 		19.5
(-1.8)
A 		6.7
(-2.9)
A 		72.3
(3)
A 		66
B 5.7
(-3)
A 		6.3
(-2.9)
A 		8.5
(-2.7)
A 		68
(3)
A 		62
C 6.6
(-3)
A 		62.9
(0.2)
A 		9
(-2.9)
A 		113.3
(3)
A 		107
avr 6.1
(-3) 		29.6
(-1.2) 		8.1
(-2.8) 		84.5
(3) 		78

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 43
1 2 3 4 5 6 range
A 18.1
(0.1)
A 		7.3
(-2.3)
A 		29.7
(2.7)
A 		4.3
(-3)
A 		10
(-1.7)
A 		31
(3)
A 		27
B 40.5
(3)
A 		5.7
(-2.7)
A 		8.5
(-2.3)
A 		4.1
(-3)
A 		36.8
(2.4)
A 		5.5
(-2.8)
A 		36
C 21.2
(-0.5)
A 		20.8
(-0.5)
A 		45.9
(3)
A 		8.5
(-2.3)
A 		3.3
(-3)
A 		13.9
(-1.5)
A 		43
avr 26.6
(2.6) 		11.3
(-1.5) 		28
(3) 		5.6
(-3) 		16.7
(-0) 		16.8
(0) 		22
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 18
1 2 3 4 range
A 2.1
(-2.8)
A 		4.2
(-1.4)
A 		1.8
(-3)
A 		10.6
(3)
A 		9
B 1.8
(-2.9)
A 		1.5
(-3)
A 		2
(-2.8)
A 		14.5
(3)
A 		13
C 2.2
(-3)
A 		18.1
(2.6)
A 		3.2
(-2.6)
A 		19.1
(3)
A 		17
avr 2
(-3) 		7.9
(-0.2) 		2.3
(-2.9) 		14.7
(3) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 14
1 2 3 4 5 6 range
A 3.3
(-1)
A 		2.6
(-1.6)
A 		6.5
(2)
A 		1.1
(-3)
A 		3
(-1.2)
A 		7.6
(3)
A 		7
B 14.1
(2.7)
A 		1.9
(-2.7)
A 		2.1
(-2.6)
A 		1.1
(-3)
A 		14.9
(3)
A 		2.1
(-2.6)
A 		14
C 7.9
(0.8)
A 		6.3
(-0.1)
A 		11.7
(3)
A 		1.7
(-2.7)
A 		1.1
(-3)
A 		4.7
(-1)
A 		11
avr 8.4
(3) 		3.6
(-1.1) 		6.8
(1.6) 		1.3
(-3) 		6.3
(1.2) 		4.8
(-0) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189809_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18041
Sequence Type Exemplar sequence
Representative Public ID F16B12.2 NCBI
Target Description F16B12.2 /REP_DB=WormBase Gene ID /WP=CE09426 /TR=Q93519 /GB=CAB02963.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=APX-1 like protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077945(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077945 NCBI Caenorhabditis elegans Delta/Serrate/Lag-2 domain family member (dsl-4) (dsl-4) mRNA, complete cds. 11/11 None
GENEFINDER00000024905 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:14085490:14095410:1 11/11 None
F16B12.2 ENSEMBL cdna:known chromosome:CEL140:X:14090905:14091974:1 gene:F16B12.2 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000024897 4/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:14090904-14091974(+) 90.51 100.0
Public Domain and Genome References
Gene Title APX-1 like protein
Gene Symbol dsl-4
Ensembl F16B12.2
Entrez Gene 184563 Entrez gene
SwissProt Q93519 EMBL-EBI
WormBase CE09426 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB02962 Hypothetical protein F16B12.1 [Caenorhabditis elegans] ref|NP_510345.2| F16B12.1 [Caenorhabditis elegans] 0.0
blast CAB02963 Hypothetical protein F16B12.2 [Caenorhabditis elegans] ref|NP_510346.1| Delta/Serrate/Lag-2 domain family member (dsl-4) [Caenorhabditis elegans] 1.0E-166
blast CAB02963 Hypothetical protein F16B12.2 [Caenorhabditis elegans] ref|NP_510346.1| Delta/Serrate/Lag-2 domain family member (dsl-4) [Caenorhabditis elegans] 1.0E-155
blast CAE63033 Hypothetical protein CBG07297 [Caenorhabditis briggsae] 7.0E-99
blast CAE74150 Hypothetical protein CBG21821 [Caenorhabditis briggsae] 2.0E-33
blast CAD45191 Delta2 protein [Cupiennius salei] 6.0E-30
Protein Domains
Database ID Description E-Value
Pfam IPR006209 EMBL-EBI EGF-like domain 4.4E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 4.9E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 4.4E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 4.9E-7
Pfam IPR000859 EMBL-EBI CUB 8.6E-5
Pfam IPR000859 EMBL-EBI CUB 6.1E-15
Pfam IPR005135 EMBL-EBI Endonuclease/exonuclease/phosphatase 1.0E-7
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000024905 1 625-647
Sequence
Target Sequence 
>C. ELEGANS:189809_AT
gggtatagtgggccgaattgcgataaagtagattgtccgttcaactgtcataatcatggg
agctgtgaagttcctggaaaatgtatgtgttctcaaggttttttcggaacgtactgtgaa
tattgcaagccttcaactacttgtaaacatggtgcagtgttagtaaatgaacttgggtgc
catccttacacttgtcgctgttttgaaggatacgctggagataatggcgacaaagatgac
gtttgctattatgcaaaaccatgccgacatggaaattgcgtatccaatgttacagtttct
ggaggatttgagtgtatatgccccaaagcttttggtggccgacgatgtgaaaaaagaata
gcacgatgggattgcagtgatgaaggttattgtcaaaacaaaggagtatgctcattcgtt
gatggtattagcagatgtagatgtgcagttggttttacaggaaagcattgtgaaaggaaa
actgcaaaaacgtgtttgaaaaagaaatgtcgggagggatttatatgtataatagacaac
aaaaaaacaggaacaatgccttgcttcaattactccaaaacctcgtctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGGTATAGTGGGCCGAATTGCGATA 169 495 163 Antisense
GTAGATTGTCCGTTCAACTGTCATA 155 457 190 Antisense
GTATGTGTTCTCAAGGTTTTTTCGG 152 455 245 Antisense
GAATATTGCAAGCCTTCAACTACTT 73 327 280 Antisense
ATGAACTTGGGTGCCATCCTTACAC 159 21 329 Antisense
ATCCTTACACTTGTCGCTGTTTTGA 42 39 344 Antisense
GAGTGTATATGCCCCAAAGCTTTTG 635 399 472 Antisense
AAAGCTTTTGGTGGCCGACGATGTG 685 121 487 Antisense
GGAGTATGCTCATTCGTTGATGGTA 476 517 565 Antisense
GGAACAATGCCTTGCTTCAATTACT 68 529 712 Antisense
TTCAATTACTCCAAAACCTCGTCTC 92 685 727 Antisense
Sequence Source Affymetrix Proprietary Database