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[189807_at] MIP family protein

Description M02F4.8 /REP_DB=WormBase Gene ID /WP=CE04769 /TR=Q21473 /GB=AAA83205.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=MIP family protein
Cluster 6grp_highest_10_10 > 03      6grp_high1_10_10 > 22      4grp_highest_8_8 > 40      4grp_high_8_8 > 50      6grp_highest_nonorm > 06      6grp_total > 22      4grp_total > 53      6grp_highest_sub > De      6grp_cgc > 61      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Hat      6grp_rule_based > S2      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 12087
1 2 3 4 range
A 12861.2
(3)
P 		11007.1
(2)
P 		9009.2
(1)
P 		1526.7
(-3)
P 		11335
B 13502.3
(3)
P 		10662.9
(1.6)
P 		9987.8
(1.3)
P 		1415.4
(-3)
P 		12087
C 12209.6
(3)
P 		10109.9
(1.8)
P 		8701.5
(1)
P 		1445.9
(-3)
P 		10764
avr 12857.7
(3) 		10593.3
(1.8) 		9232.8
(1.1) 		1462.7
(-3) 		11395

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 10645
1 2 3 4 5 6 range
A 13438.5
(3)
P 		12334.5
(2.4)
P 		12054.3
(2.2)
P 		9392.2
(0.6)
P 		7763.8
(-0.3)
P 		3228.4
(-3)
P 		10210
B 9593.5
(1.6)
P 		11559.7
(3)
P 		9334.9
(1.4)
P 		10012.3
(1.9)
P 		7732.4
(0.3)
P 		3067.7
(-3)
P 		8492
C 10717.9
(1.7)
P 		11827.3
(2.4)
P 		12868.7
(3)
P 		8244.6
(0.2)
P 		8437.6
(0.4)
P 		2793.8
(-3)
P 		10075
avr 11250
(2.6) 		11907.2
(3) 		11419.3
(2.7) 		9216.4
(1.2) 		7977.9
(0.3) 		3030
(-3) 		8877
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4459
1 2 3 4 range
A 4682.8
(3)
P 		2389.3
(-0.1)
P 		2355.2
(-0.1)
P 		223.5
(-3)
P 		4459
B 4305.8
(3)
P 		2633.5
(0.5)
P 		2314.4
(0)
P 		301.6
(-3)
P 		4004
C 4041.7
(3)
P 		2906.7
(1.2)
P 		3032.7
(1.4)
P 		243.8
(-3)
P 		3798
avr 4343.4
(3) 		2643.2
(0.5) 		2567.4
(0.4) 		256.3
(-3) 		4087

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3601
1 2 3 4 5 6 range
A 2477.3
(-0.2)
P 		4386.7
(3)
P 		2625.2
(0.1)
P 		2382.1
(-0.3)
P 		2342.8
(-0.4)
P 		786
(-3)
P 		3601
B 3338.1
(1.9)
P 		3847.7
(3)
P 		2266.8
(-0.5)
P 		2651.9
(0.3)
P 		3141.6
(1.4)
P 		1143.9
(-3)
P 		2704
C 3972.6
(3)
P 		3608.9
(2.3)
P 		3275.3
(1.6)
P 		1658
(-1.6)
P 		2730.3
(0.5)
P 		935.2
(-3)
P 		3037
avr 3262.7
(1.6) 		3947.8
(3) 		2722.4
(0.5) 		2230.7
(-0.4) 		2738.2
(0.6) 		955
(-3) 		2993
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189807_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18383
Sequence Type Exemplar sequence
Representative Public ID M02F4.8 NCBI
Target Description M02F4.8 /REP_DB=WormBase Gene ID /WP=CE04769 /TR=Q21473 /GB=AAA83205.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=MIP family protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076114(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076114 NCBI Caenorhabditis elegans AQuaPorin or aquaglyceroporin related family member (aqp-7) (aqp-7) mRNA, complete cds. 11/11 None
SNAP00000027796 ENSEMBL cdna:SNAP chromosome:CEL140:X:3025527:3026697:1 11/11 None
GENEFINDER00000027803 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:3025527:3027292:1 11/11 None
M02F4.8.1 ENSEMBL cdna:known chromosome:CEL140:X:3025527:3027124:1 gene:M02F4.8 11/11 None
M02F4.8.2 ENSEMBL cdna:known chromosome:CEL140:X:3025527:3026877:1 gene:M02F4.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:3025115-3026697(+) 100.0 100.0
Public Domain and Genome References
Gene Title MIP family protein
Gene Symbol aqp-7
Ensembl M02F4.8
Entrez Gene 180589 Entrez gene
SwissProt Q21473 EMBL-EBI
WormBase CE34058 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.26323.1.S1_AT similar to aquaporin 10 cfa
U133_X3P:HS2AFFX.1.212.S1_3P_S_AT aquaporin 10 hs
HG-U133_PLUS_2:1555338_S_AT aquaporin 10 hs
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5215 transporter activity inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA83205 Aquaporin or aquaglyceroporin related protein 7 [Caenorhabditis elegans] ref|NP_508515.2| AQuaPorin or aquaglyceroporin related family member (aqp-7) [Caenorhabditis elegans] 1.0E-151
blast AAA83205 Aquaporin or aquaglyceroporin related protein 7 [Caenorhabditis elegans] ref|NP_508515.2| AQuaPorin or aquaglyceroporin related family member (aqp-7) [Caenorhabditis elegans] 1.0E-149
blast CAE68364 Hypothetical protein CBG14117 [Caenorhabditis briggsae] 1.0E-137
Protein Domains
Database ID Description E-Value
Pfam IPR000425 EMBL-EBI Major intrinsic protein 6.6E-43
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508515.2 6 21-43,53-75,101-123,160-179,192-214,239-261
M02F4.8.1 6 21-43,53-75,101-123,160-179,192-214,239-261
M02F4.8.2 6 21-43,53-75,101-123,160-179,192-214,239-261
SNAP00000027796 6 21-43,53-75,101-123,160-179,192-214,239-261
GENEFINDER00000027803 6 21-43,53-75,101-123,160-179,192-214,239-261
Sequence
Target Sequence 
>C. ELEGANS:189807_AT
caaagatttcctcgtctactgtgtcgtccaaaccataggtgccgctcttggatctgctgc
cgcttttggactttactatgatcaatttgtcaagtttgccggagcttaccgcaccatcct
cgggccaaaggctacagccggatgcttctgctcttatccagctcttcatgtttccaacac
caccgccttcttcgatcaatttgctggaactgctcttcttgtgctcttcgtttgcgtcgt
cattgataagagaaacggaatcccaggagccgctcacccacttctctttggacttgtcgt
catgatgatcggaactgcctatggaatgaacctcggatacccaatcaacccagctcgtga
tctcggaccaagacttttcagtttcttcatctacggatctggagtcttcagctaccactc
gtactacttctggatcccagtcattgctccacttttcggtgctatcttcggagcctggtc
ctacacattcttcgttggagctcacattccagatcaacgcgaaaccacctatgtccttgt
tgatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAAAGATTTCCTCGTCTACTGTGTC 72 193 339 Antisense
AAACCATAGGTGCCGCTCTTGGATC 595 125 368 Antisense
TCAAGTTTGCCGGAGCTTACCGCAC 556 627 428 Antisense
AAAGGCTACAGCCGGATGCTTCTGC 493 121 465 Antisense
CAATTTGCTGGAACTGCTCTTCTTG 322 181 535 Antisense
CACTTCTCTTTGGACTTGTCGTCAT 375 197 617 Antisense
GATCTGGAGTCTTCAGCTACCACTC 123 419 734 Antisense
TACCACTCGTACTACTTCTGGATCC 80 649 751 Antisense
CACTTTTCGGTGCTATCTTCGGAGC 414 197 788 Antisense
GGTCCTACACATTCTTCGTTGGAGC 70 503 815 Antisense
GAAACCACCTATGTCCTTGTTGATG 406 357 859 Antisense
Sequence Source Affymetrix Proprietary Database