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[189798_s_at] GTP-binding protein

Description D2013.5 /REP_DB=WormBase Gene ID /WP=CE00930 /TR=Q18965 /GB=CAA87771.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=GTP-binding protein
Cluster 6grp_highest_10_10 > 53      6grp_high1_10_10 > 35      4grp_highest_8_8 > 43      4grp_high_8_8 > 48      6grp_highest_nonorm > 60      6grp_total > 35      4grp_total > 55      6grp_highest_sub > 02      6grp_cgc > 34      6grp_high1_sub > 02      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 419
1 2 3 4 range
A 593.7
(3)
P 		206.6
(-3)
P 		211
(-2.9)
P 		250.5
(-2.3)
P 		387
B 502.7
(3)
P 		175.7
(-3)
P 		266.7
(-1.3)
P 		207.7
(-2.4)
P 		327
C 595
(3)
P 		224.8
(-2.5)
P 		452.4
(0.9)
P 		191.4
(-3)
P 		404
avr 563.8
(3) 		202.4
(-3) 		310
(-1.2) 		216.5
(-2.8) 		361

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 376
1 2 3 4 5 6 range
A 204.8
(-2.8)
P 		419.4
(3)
P 		395.7
(2.4)
P 		337.3
(0.8)
P 		199
(-3)
P 		257.5
(-1.4)
P 		220
B 568.7
(3)
P 		496
(1.8)
P 		528.3
(2.3)
P 		284.6
(-1.8)
P 		217
(-3)
P 		344.3
(-0.8)
P 		352
C 465.9
(1.9)
P 		528.3
(3)
P 		297.9
(-1.1)
P 		259.7
(-1.8)
P 		193
(-3)
P 		364.4
(0.1)
P 		335
avr 413.1
(1.5) 		481.2
(3) 		407.3
(1.4) 		293.9
(-1) 		203
(-3) 		322.1
(-0.4) 		278
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 184
1 2 3 4 range
A 216.2
(3)
P 		44.8
(-2.7)
P 		55.1
(-2.4)
P 		36.7
(-3)
P 		180
B 160.3
(3)
P 		43.4
(-3)
P 		61.8
(-2.1)
P 		44.3
(-3)
P 		117
C 197
(3)
P 		64.6
(-1.8)
P 		157.7
(1.6)
P 		32.3
(-3)
P 		165
avr 191.2
(3) 		50.9
(-2.5) 		91.5
(-0.9) 		37.8
(-3) 		153

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 160
1 2 3 4 5 6 range
A 37.8
(-3)
P 		149.2
(3)
P 		86.2
(-0.4)
P 		85.6
(-0.4)
P 		60.1
(-1.8)
P 		62.7
(-1.7)
P 		111
B 197.9
(3)
P 		165.1
(1.4)
P 		128.3
(-0.4)
P 		75.4
(-3)
P 		88.2
(-2.4)
P 		128.4
(-0.4)
P 		123
C 172.7
(3)
P 		161.2
(2.4)
P 		75.8
(-1.8)
P 		52.2
(-3)
P 		62.4
(-2.5)
P 		122
(0.5)
P 		121
avr 136.1
(1.5) 		158.5
(3) 		96.8
(-1.2) 		71.1
(-2.9) 		70.2
(-3) 		104.4
(-0.7) 		88
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189798_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3918
Sequence Type Exemplar sequence
Representative Public ID D2013.5 NCBI
Target Description D2013.5 /REP_DB=WormBase Gene ID /WP=CE00930 /TR=Q18965 /GB=CAA87771.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=GTP-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063585(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063585 NCBI Caenorhabditis elegans EATing: abnormal pharyngeal pumping family member (eat-3) (eat-3) mRNA, complete cds. 9/11 None
SNAP00000019826 ENSEMBL cdna:SNAP chromosome:CEL140:II:9325944:9329198:1 9/11 None
GENEFINDER00000019838 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:9324800:9329198:1 9/11 None
D2013.5 ENSEMBL cdna:known chromosome:CEL140:II:9324786:9329567:1 gene:D2013.5 9/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:9324796-9329235(+) 100.0 100.0
Public Domain and Genome References
Gene Title GTP-binding protein
Gene Symbol eat-3
Ensembl D2013.5
Entrez Gene 174476 Entrez gene
SwissProt Q18965 EMBL-EBI
WormBase CE32846 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1606031_AT similar to optic atrophy 1 isoform 8 cfa
CANINE:1587655_AT similar to optic atrophy 1 isoform 8 cfa
CANINE_2:CFA.1129.1.S1_AT similar to optic atrophy 1 isoform 8 cfa
CANINE_2:CFA.1129.1.S1_S_AT similar to optic atrophy 1 isoform 8 cfa
CANINE_2:CFA.1129.2.S1_AT similar to optic atrophy 1 isoform 8 cfa
CANINE_2:CFA.18132.1.S1_AT similar to optic atrophy 1 isoform 8 cfa
CANINE_2:CFA.18132.1.S1_S_AT similar to optic atrophy 1 isoform 8 cfa
CANINE_2:CFA.19901.1.S1_S_AT similar to optic atrophy 1 isoform 8 cfa
DROSOPHILA_2:1626840_A_AT dm
DROSGENOME1:152526_AT dm
CHICKEN:GGAAFFX.22169.1.S1_S_AT similar to optic atrophy 1 isoform 7 gga
CHICKEN:GGAAFFX.22169.2.S1_AT similar to optic atrophy 1 isoform 7 gga
HG-U133_PLUS_2:241027_AT optic atrophy 1 (autosomal dominant) hs
HG-U133B:241027_AT optic atrophy 1 (autosomal dominant) hs
HG-U133_PLUS_2:214306_AT optic atrophy 1 (autosomal dominant) hs
HG-U133A_2:214306_AT optic atrophy 1 (autosomal dominant) hs
HG-U133A:214306_AT optic atrophy 1 (autosomal dominant) hs
HU35KSUBA:RC_AA412298_AT optic atrophy 1 (autosomal dominant) hs
HU35KSUBA:HUM_ALU_AT optic atrophy 1 (autosomal dominant) hs
HU35KSUBB:HUM_ALU_AT optic atrophy 1 (autosomal dominant) hs
HU35KSUBC:HUM_ALU_AT optic atrophy 1 (autosomal dominant) hs
HU35KSUBD:HUM_ALU_AT optic atrophy 1 (autosomal dominant) hs
HUGENEFL:HUM_ALU_AT optic atrophy 1 (autosomal dominant) hs
HC-G110:HUM_ALU_AT optic atrophy 1 (autosomal dominant) hs
HU35KSUBC:RC_N39103_AT optic atrophy 1 (autosomal dominant) hs
HU35KSUBC:RC_AA130235_AT optic atrophy 1 (autosomal dominant) hs
U133_X3P:HS.147946.1.S1_3P_AT optic atrophy 1 (autosomal dominant) hs
U133_X3P:HS.147946.0.S2_3P_S_AT optic atrophy 1 (autosomal dominant) hs
U133_X3P:HS.147946.0.S1_3P_AT optic atrophy 1 (autosomal dominant) hs
U133_X3P:HS.131273.0.A1_3P_AT optic atrophy 1 (autosomal dominant) hs
HG-U133A_2:212213_X_AT optic atrophy 1 (autosomal dominant) hs
HG-U133_PLUS_2:212213_X_AT optic atrophy 1 (autosomal dominant) hs
HG-U133A:212213_X_AT optic atrophy 1 (autosomal dominant) hs
HG-U133A_2:212214_AT optic atrophy 1 (autosomal dominant) hs
HG-U133_PLUS_2:212214_AT optic atrophy 1 (autosomal dominant) hs
HG-U133A:212214_AT optic atrophy 1 (autosomal dominant) hs
HG-U95AV2:39745_AT optic atrophy 1 (autosomal dominant) hs
HG-U133_PLUS_2:216287_AT Optic atrophy 1 (autosomal dominant) hs
HG-U133A_2:216287_AT Optic atrophy 1 (autosomal dominant) hs
HG-U133A:216287_AT Optic atrophy 1 (autosomal dominant) hs
HG-U95C:51532_AT Optic atrophy 1 (autosomal dominant) hs
HG-U95C:61560_R_AT Optic atrophy 1 (autosomal dominant) hs
HU35KSUBD:RC_N23897_AT Optic atrophy 1 (autosomal dominant) hs
MOE430A:1418768_AT optic atrophy 1 homolog (human) mm
MOUSE430A_2:1418768_AT optic atrophy 1 homolog (human) mm
MOUSE430_2:1418768_AT optic atrophy 1 homolog (human) mm
MG-U74BV2:109411_AT optic atrophy 1 homolog (human) mm
MG-U74CV2:171396_AT optic atrophy 1 homolog (human) mm
MOE430A:1449214_A_AT optic atrophy 1 homolog (human) mm
MOUSE430A_2:1449214_A_AT optic atrophy 1 homolog (human) mm
MOUSE430_2:1449214_A_AT optic atrophy 1 homolog (human) mm
MOE430B:1434890_AT optic atrophy 1 homolog (human) mm
MOUSE430_2:1434890_AT optic atrophy 1 homolog (human) mm
MG-U74BV2:110757_AT Optic atrophy 1 homolog (human), mRNA (cDNA clone IMAGE:4019536) mm
MU19KSUBA:TC22064_AT Optic atrophy 1 homolog (human), mRNA (cDNA clone IMAGE:4019536) mm
MU19KSUBA:TC24745_AT Optic atrophy 1 homolog (human), mRNA (cDNA clone IMAGE:4019536) mm
MU19KSUBA:TC24745_G_AT Optic atrophy 1 homolog (human), mRNA (cDNA clone IMAGE:4019536) mm
MU19KSUBB:TC33393_AT Optic atrophy 1 homolog (human), mRNA (cDNA clone IMAGE:4019536) mm
MU19KSUBC:TC39083_AT Optic atrophy 1 homolog (human), mRNA (cDNA clone IMAGE:4019536) mm
RG-U34A:U93197_AT optic atrophy 1 homolog (human) rn
RAE230A:1387225_AT optic atrophy 1 homolog (human) rn
RAT230_2:1387225_AT optic atrophy 1 homolog (human) rn
RAE230A:1372334_AT Optic atrophy 1 homolog (human) rn
RAT230_2:1372334_AT Optic atrophy 1 homolog (human) rn
RAE230B:1384608_AT Optic atrophy 1 homolog (human) rn
RAT230_2:1384608_AT Optic atrophy 1 homolog (human) rn
RG-U34B:RC_AA851026_AT Optic atrophy 1 homolog (human) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA87771 Hypothetical protein D2013.5 [Caenorhabditis elegans] ref|NP_495986.2| EATing: abnormal pharyngeal pumping family member (eat-3) [Caenorhabditis elegans] 0.0
blast CAE72910 Hypothetical protein CBG20228 [Caenorhabditis briggsae] 0.0
blast XP_623413 PREDICTED: similar to ENSANGP00000008246 [Apis mellifera] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001401 EMBL-EBI Dynamin 5.6E-17
Pfam IPR001401 EMBL-EBI Dynamin 5.6E-17
Sequence
Target Sequence 
>C. ELEGANS:189798_S_AT
cattcaggacgagctttactcaattttaggagcagatccagagcacaaacaggcgttgac
tgatgatgatattactgtaatcagaagaaatattgagacgaaaggcgtacttgaagttcc
cactgaatcgattagaaaacaatggaaattagtatttaagaagcactttttggagaggat
aattaatagcagcaaggactgtctatcgatgtatcagatgtatcgtcaaggaatgattga
aggacaagatatcgattgccaaaccatcgtacttttctacagaatccaaaagatggtcaa
cttgacgtgtaacgcactgcggcaacaaatcacaaatactgaacacagaaggctggaaaa
agagattaaggaggtgttggatgattggtcacaagagccagatattaaaaagaaatattt
gacgggaagacgtgtcgatcttgcagaagaaattcgtatgtttttttctgatcttcaaat
ttttattaatgaaaacctggatttctcatgcaaaaacaagttcgccgaatccaagagaaa
ctcgaagagttcatggctcaatt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATTCAGGACGAGCTTTACTCAATT 189 217 2295 Antisense
GAGCACAAACAGGCGTTGACTGATG 701 389 2335 Antisense
GCGTACTTGAAGTTCCCACTGAATC 576 287 2399 Antisense
GCAAGGACTGTCTATCGATGTATCA 496 321 2486 Antisense
TTGCCAAACCATCGTACTTTTCTAC 290 681 2550 Antisense
ACTTGACGTGTAACGCACTGCGGCA 710 101 2594 Antisense
GACGGGAAGACGTGTCGATCTTGCA 382 377 2715 Antisense
ATTCGTATGTTTTTTTCTGATCTTC 526 9 2746 Antisense
ATGAAAACCTGGATTTCTCATGCAA 321 45 2783 Antisense
CAAGTTCGCCGAATCCAAGAGAAAC 553 183 2811 Antisense
AACTCGAAGAGTTCATGGCTCAATT 325 141 2833 Antisense
Sequence Source Affymetrix Proprietary Database