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[189787_at] carrier protein

Description C16C10.1 /REP_DB=WormBase Gene ID /WP=CE01489 /TR=SW:Q09461 /GB=CAA86739.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=carrier protein
Cluster 6grp_total > 97      4grp_total > 40      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 106
1 2 3 4 range
A 165.9
(2.4)
A 		158.7
(-3)
A 		159.7
(-2.3)
A 		166.7
(3)
A 		8
B 120.1
(-3)
A 		142.1
(-1.2)
A 		192.8
(3)
A 		172.7
(1.3)
A 		73
C 103.1
(-3)
A 		208.8
(3)
A 		204.1
(2.7)
A 		170
(0.8)
A 		106
avr 129.7
(-3) 		169.9
(1.3) 		185.5
(3) 		169.8
(1.3) 		56

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 267
1 2 3 4 5 6 range
A 163.1
(-2.5)
A 		142.8
(-3)
A 		159.7
(-2.6)
P 		159.8
(-2.6)
A 		271.2
(0.2)
P 		382.6
(3)
P 		240
B 136.7
(-2.8)
A 		130.2
(-3)
A 		188.2
(-1.2)
A 		143.5
(-2.6)
A 		312.1
(2.6)
P 		326.6
(3)
P 		196
C 188.1
(-1)
P 		149.4
(-2.1)
A 		115.8
(-3)
A 		255.6
(0.8)
M 		252
(0.7)
P 		334.3
(3)
P 		219
avr 162.6
(-2.4) 		140.8
(-3) 		154.6
(-2.6) 		186.3
(-1.7) 		278.4
(1) 		347.8
(3) 		207
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 47
1 2 3 4 range
A 60.4
(3)
A 		34.5
(-1.3)
A 		41.7
(-0.1)
A 		24.4
(-3)
A 		36
B 38.3
(-1)
A 		35.1
(-3)
A 		44.7
(3)
A 		36.8
(-1.9)
A 		10
C 34.1
(-2.2)
A 		60
(1.4)
A 		71.1
(3)
A 		28.7
(-3)
A 		42
avr 44.3
(0.8) 		43.2
(0.5) 		52.5
(3) 		30
(-3) 		23

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 97
1 2 3 4 5 6 range
A 30.1
(-3)
A 		50.8
(-1)
A 		34.8
(-2.6)
P 		40.5
(-2)
A 		81.9
(1.9)
P 		93.2
(3)
P 		63
B 47.6
(-2.4)
A 		43.3
(-2.6)
A 		45.7
(-2.5)
A 		38
(-3)
A 		126.8
(3)
P 		121.8
(2.7)
P 		89
C 69.7
(-0.1)
P 		45.6
(-1.8)
A 		29.5
(-3)
A 		51.4
(-1.4)
M 		81.5
(0.8)
P 		111.9
(3)
P 		82
avr 49.1
(-2) 		46.6
(-2.2) 		36.7
(-3) 		43.3
(-2.5) 		96.7
(2) 		109
(3) 		72
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189787_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6622
Sequence Type Exemplar sequence
Representative Public ID C16C10.1 NCBI
Target Description C16C10.1 /REP_DB=WormBase Gene ID /WP=CE01489 /TR=SW:Q09461 /GB=CAA86739.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=carrier protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065435(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065435 NCBI Caenorhabditis elegans C16C10.1 (C16C10.1) mRNA, complete cds. 11/11 None
SNAP00000043778 ENSEMBL cdna:SNAP chromosome:CEL140:III:4179033:4181403:-1 11/11 None
GENEFINDER00000043784 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4179033:4181403:-1 11/11 None
C16C10.1.2 ENSEMBL cdna:known chromosome:CEL140:III:4179033:4181411:-1 gene:C16C10.1 11/11 None
C16C10.1.1 ENSEMBL cdna:known chromosome:CEL140:III:4179033:4181409:-1 gene:C16C10.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4179032-4181403(-) 100.0 100.0
Public Domain and Genome References
Gene Title carrier protein
Ensembl C16C10.1
Entrez Gene 175537 Entrez gene
SwissProt Q09461 EMBL-EBI
WormBase CE33519 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:15325_AT mitochondrial substrate carrier family protein at
ATH1-121501:253824_AT mitochondrial substrate carrier family protein at
CANINE:1605580_AT similar to mitochondrial carrier family protein cfa
CANINE_2:CFA.18876.1.S1_AT similar to mitochondrial carrier family protein cfa
CANINE_2:CFA.18876.1.S1_S_AT similar to mitochondrial carrier family protein cfa
CANINE_2:CFA.19588.1.S1_AT similar to mitochondrial carrier family protein cfa
CANINE_2:CFAAFFX.3669.1.S1_AT similar to mitochondrial carrier family protein cfa
HG-U133_PLUS_2:205716_AT mitochondrial carrier family protein hs
HG-U133A:205716_AT mitochondrial carrier family protein hs
HG-FOCUS:205716_AT mitochondrial carrier family protein hs
HG-U133A_2:205716_AT mitochondrial carrier family protein hs
HU35KSUBA:AA401605_AT mitochondrial carrier family protein hs
U133_X3P:G10047121_3P_AT mitochondrial carrier family protein hs
U133_X3P:HS.208414.0.A1_3P_AT mitochondrial carrier family protein hs
HG-U133_PLUS_2:227012_AT mitochondrial carrier family protein hs
HG-U133B:227012_AT mitochondrial carrier family protein hs
HG-U95AV2:35465_AT Mitochondrial carrier family protein hs
MG-U74BV2:112210_AT RIKEN cDNA B230315F11 gene mm
MOE430B:1438005_AT RIKEN cDNA B230315F11 gene mm
MOUSE430_2:1438005_AT RIKEN cDNA B230315F11 gene mm
MOUSE430_2:1458031_AT RIKEN cDNA B230315F11 gene, mRNA (cDNA clone MGC:103255 IMAGE:30726859) mm
MOE430B:1458031_AT RIKEN cDNA B230315F11 gene, mRNA (cDNA clone MGC:103255 IMAGE:30726859) mm
MU19KSUBC:TC38645_AT RIKEN cDNA B230315F11 gene, mRNA (cDNA clone MGC:103255 IMAGE:30726859) mm
RG-U34C:RC_AI233762_AT similar to mitochondrial carrier family protein (predicted) rn
YEAST_2:1778000_AT Mitochondrial protein of the mitochondrial carrier family, involved in activating mitochondrial Sod2p probably by facilitating insertion of an essential manganese cofactor Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5488 binding inferred from electronic annotation QuickGO AmiGO
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA86739 Hypothetical protein C16C10.1 [Caenorhabditis elegans] ref|NP_497836.2| C16C10.1 [Caenorhabditis elegans] sp|Q09461|YQ51_CAEEL Putative mitochondrial carrier C16C10.1 0.0
blast CAE72859 Hypothetical protein CBG20158 [Caenorhabditis briggsae] 1.0E-157
blast CAE72859 Hypothetical protein CBG20158 [Caenorhabditis briggsae] 1.0E-156
blast CAE72859 Hypothetical protein CBG20158 [Caenorhabditis briggsae] 1.0E-152
Protein Domains
Database ID Description E-Value
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 9.8E-25
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.7E-27
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.4E-22
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 9.8E-25
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.7E-27
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.4E-22
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.7E-19
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.7E-27
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.4E-22
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497836.2 4 125-147,174-196,225-247,267-289
C16C10.1.2 4 125-147,174-196,225-247,267-289
C16C10.1.1 4 125-147,174-196,225-247,267-289
SNAP00000043778 4 111-133,160-182,211-233,253-275
GENEFINDER00000043784 4 158-180,207-229,258-280,300-322
Sequence
Target Sequence 
>C. ELEGANS:189787_AT
tgtgttgccgacgggcattttctccggaaaaatggacgcctcctgattggtcagctgcag
cagtggctggaattgtagcaagaaccattgcggttacggtagtcagtcccattgagatga
ttcgtacgaaaatgcaaagcaagaggcttacttatcatgaaatcggtcacctggtgcgta
gttcaatggcaaccaaaggaatctccagtttctacctcggttggacgcccacaatgctcc
gtgatattccattttctggaatctactgggctggatatgatttattcaaaacaaatcttc
aacgacgtcaaggacctgatcacaatccgtttgtagtgtcattcgtgagcggagcagctg
caggagttgtcgcctcgatattcacacatccatttgatgttataaagacgaattgtcaga
ttagaattggtggaagtattgatgatatgaataaatcaattacaacagttatcaaggata
tgtatcattcgagaggaatttcagcgttttcttcaggtcttgtcccacgcctcgtcaaag
tttcaccatcctgtgccatcatgatcagc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGTGTTGCCGACGGGCATTTTCTCC 588 555 389 Antisense
AAAATGGACGCCTCCTGATTGGTCA 388 133 417 Antisense
GTTACGGTAGTCAGTCCCATTGAGA 344 443 481 Antisense
AATCGGTCACCTGGTGCGTAGTTCA 476 167 549 Antisense
AAAGGAATCTCCAGTTTCTACCTCG 81 111 583 Antisense
TGCTCCGTGATATTCCATTTTCTGG 460 581 623 Antisense
GTCAAGGACCTGATCACAATCCGTT 367 463 695 Antisense
ACAATCCGTTTGTAGTGTCATTCGT 239 113 710 Antisense
GTCATTCGTGAGCGGAGCAGCTGCA 155 469 726 Antisense
AGTTGTCGCCTCGATATTCACACAT 514 65 753 Antisense
ACCATCCTGTGCCATCATGATCAGC 402 83 933 Antisense
Sequence Source Affymetrix Proprietary Database