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[189779_at] ras-related protein

Description T01B7.3 /REP_DB=WormBase Gene ID /WP=CE03587 /TR=Q22045 /GB=CAA91296.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=ras-related protein
Cluster 6grp_highest_10_10 > 89      6grp_high1_10_10 > 98      4grp_highest_8_8 > 23      4grp_high_8_8 > 06      6grp_highest_nonorm > 94      6grp_total > 95      4grp_total > 02      6grp_highest_sub > In      6grp_cgc > 78      6grp_high1_sub > In      6grp_cgc_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1766
1 2 3 4 range
A 486.8
(-2.5)
P 		421.3
(-2.7)
P 		341.2
(-3)
P 		2107.3
(3)
P 		1766
B 520.2
(-2.5)
P 		459
(-2.8)
P 		405.6
(-3)
P 		1854.5
(3)
P 		1449
C 518.5
(-2.6)
P 		450.9
(-2.9)
P 		417.3
(-3)
P 		1997.2
(3)
P 		1580
avr 508.5
(-2.5) 		443.7
(-2.8) 		388
(-3) 		1986.3
(3) 		1598

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 516
1 2 3 4 5 6 range
A 410.6
(-3)
P 		465.1
(-2.2)
P 		419.6
(-2.9)
P 		743
(2.1)
P 		653.8
(0.7)
P 		803.1
(3)
P 		393
B 373.5
(-2.5)
P 		382.5
(-2.4)
P 		330.2
(-3)
P 		498.6
(-1)
P 		832.4
(3)
P 		801.6
(2.6)
P 		502
C 459.9
(-2)
P 		385.5
(-3)
P 		515.8
(-1.3)
P 		609.1
(-0.1)
P 		846.2
(3)
P 		791.1
(2.3)
P 		461
avr 414.7
(-2.9) 		411
(-3) 		421.9
(-2.8) 		616.9
(0.2) 		777.5
(2.7) 		798.6
(3) 		388
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 306
1 2 3 4 range
A 177.2
(-0.6)
P 		91.5
(-2.9)
P 		89.2
(-3)
P 		308.5
(3)
P 		219
B 165.9
(-1.6)
P 		113.4
(-2.6)
P 		94
(-3)
P 		395.2
(3)
P 		301
C 171.6
(-1.8)
P 		129.6
(-3)
P 		145.4
(-2.5)
P 		336.8
(3)
P 		207
avr 171.6
(-1.4) 		111.5
(-2.9) 		109.5
(-3) 		346.8
(3) 		237

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 263
1 2 3 4 5 6 range
A 75.7
(-3)
P 		165.4
(1.4)
P 		91.4
(-2.2)
P 		188.4
(2.6)
P 		197.3
(3)
P 		195.5
(2.9)
P 		122
B 130
(-1.8)
P 		127.3
(-1.9)
P 		80.2
(-3)
P 		132.1
(-1.8)
P 		338.2
(3)
P 		298.9
(2.1)
P 		258
C 170.5
(-1)
P 		117.6
(-3)
P 		131.3
(-2.5)
P 		122.5
(-2.8)
P 		273.8
(3)
P 		264.8
(2.7)
P 		156
avr 125.4
(-2.1) 		136.8
(-1.7) 		101
(-3) 		147.7
(-1.3) 		269.8
(3) 		253.1
(2.4) 		169
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189779_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3352
Sequence Type Exemplar sequence
Representative Public ID T01B7.3 NCBI
Target Description T01B7.3 /REP_DB=WormBase Gene ID /WP=CE03587 /TR=Q22045 /GB=CAA91296.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=ras-related protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063453(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063453 NCBI Caenorhabditis elegans RAB family member (rab-21) (rab-21) mRNA, complete cds. 11/11 None
SNAP00000025603 ENSEMBL cdna:SNAP chromosome:CEL140:II:8714074:8714931:-1 11/11 None
GENEFINDER00000025631 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8714074:8714931:-1 11/11 None
T01B7.3 ENSEMBL cdna:known chromosome:CEL140:II:8714074:8714931:-1 gene:T01B7.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8714070-8714928(-) 100.0 100.0
Public Domain and Genome References
Gene Title ras-related protein
Gene Symbol rab-21
Ensembl T01B7.3
Entrez Gene 187932 Entrez gene
SwissProt Q22045 EMBL-EBI
WormBase CE03587 Wormbase
Functional Annotations
Ortholog
ID Title Organism
HG-U133_PLUS_2:203885_AT RAB21, member RAS oncogene family hs
HG-U133A:203885_AT RAB21, member RAS oncogene family hs
HG-U133A_2:203885_AT RAB21, member RAS oncogene family hs
HG-U133_PLUS_2:226268_AT RAB21, member RAS oncogene family hs
HG-U133B:226268_AT RAB21, member RAS oncogene family hs
HU35KSUBB:RC_W37481_AT RAB21, member RAS oncogene family hs
HUGENEFL:D42087_AT RAB21, member RAS oncogene family hs
U133_X3P:G7661921_3P_AT RAB21, member RAS oncogene family hs
U133_X3P:HS.154697.0.A1_3P_AT RAB21, member RAS oncogene family hs
HG-U95AV2:33326_AT RAB21, member RAS oncogene family hs
HG-U95C:59971_AT RAB21, member RAS oncogene family hs
HG-U95D:70963_R_AT RAB21, member RAS oncogene family hs
HG-U133_PLUS_2:239329_AT RAB21, member RAS oncogene family hs
HG-U133B:239329_AT RAB21, member RAS oncogene family hs
HG-U95D:82594_AT RAB21, member RAS oncogene family hs
HG-U95E:89184_AT RAB21, member RAS oncogene family hs
HU35KSUBB:RC_R46244_AT RAB21, member RAS oncogene family hs
U133_X3P:HS.167028.0.A1_3P_AT RAB21, member RAS oncogene family hs
MU11KSUBB:MSA.27913.0_S_AT RAB21, member RAS oncogene family mm
MG-U74AV2:104112_AT RAB21, member RAS oncogene family mm
MOE430A:1437742_AT RAB21, member RAS oncogene family mm
MOUSE430A_2:1437742_AT RAB21, member RAS oncogene family mm
MOUSE430_2:1437742_AT RAB21, member RAS oncogene family mm
MOE430A:1437741_AT RAB21, member RAS oncogene family mm
MOUSE430A_2:1437741_AT RAB21, member RAS oncogene family mm
MOUSE430_2:1437741_AT RAB21, member RAS oncogene family mm
MOUSE430_2:1447497_AT MKIAA0118 protein mm
MOE430B:1447497_AT MKIAA0118 protein mm
MG-U74BV2:162944_AT MKIAA0118 protein mm
MU19KSUBB:TC31912_AT MKIAA0118 protein mm
MU19KSUBB:TC32311_AT MKIAA0118 protein mm
MU19KSUBC:TC36789_AT MKIAA0118 protein mm
RG-U34C:RC_AI234149_AT RAB21, member RAS oncogene family rn
RAE230B:1383089_AT RAB21, member RAS oncogene family rn
RAT230_2:1383089_AT RAB21, member RAS oncogene family rn
RG-U34C:RC_AI104371_AT RAB21, member RAS oncogene family rn
RG-U34C:RC_AI170084_AT RAB21, member RAS oncogene family rn
RAE230A:1389331_AT RAB21, member RAS oncogene family rn
RAT230_2:1389331_AT RAB21, member RAS oncogene family rn
RAE230B:1391639_AT RAB21, member RAS oncogene family rn
RAT230_2:1391639_AT RAB21, member RAS oncogene family rn
RAE230B:1397731_AT RAB21, member RAS oncogene family rn
RAT230_2:1397731_AT RAB21, member RAS oncogene family rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6886 intracellular protein transport inferred from electronic annotation QuickGO AmiGO
7264 small GTPase mediated signal transduction inferred from electronic annotation QuickGO AmiGO
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91296 Hypothetical protein T01B7.3 [Caenorhabditis elegans] ref|NP_495854.1| RAB family member (rab-21) [Caenorhabditis elegans] 1.0E-115
blast CAE59726 Hypothetical protein CBG03162 [Caenorhabditis briggsae] 4.0E-90
blast P55745 Ras-related protein Rab-21 7.0E-56
Protein Domains
Database ID Description E-Value
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 3.9E-80
Sequence
Target Sequence 
>C. ELEGANS:189779_AT
tcaagatcgtgttgctcggcgaaggatgtgttggtaaatcatcacttgtgcttcgattcg
ttgaaaataaattcagctgcaaacacctgtcgacgattcaggcaagcttccaaaacaaaa
ctgtgaatgtagaagactgccaagctgacctacacatctgggataccgctggacaggaga
aataccacgcactcggtccaatctactatcgaggaagcaatggcgtgctactggttttcg
atatcactgatagaaagtcatttgaaaaggttaagaactgggttctcgaaataaaaacat
gcctgggaaatactgcagagattctgatagtcgggaacaagattgatcttgaagaagaac
ggcaggtcactcgacaggatgcggaagcatacgcagaatcagaaggggcattgtatatgg
agacttctgctcaggacaatgttggaatctctgatgcttttgaatctttaactgcgaaaa
tgatcgaacattcgcgtactcgttcgacagaaccaccatctacgaatcgatcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCAAGATCGTGTTGCTCGGCGAAGG 514 631 50 Antisense
TCATCACTTGTGCTTCGATTCGTTG 99 621 88 Antisense
TCAGCTGCAAACACCTGTCGACGAT 369 623 122 Antisense
GTCGACGATTCAGGCAAGCTTCCAA 539 473 138 Antisense
TAGAAGACTGCCAAGCTGACCTACA 83 653 179 Antisense
TGACCTACACATCTGGGATACCGCT 143 569 195 Antisense
GCACTCGGTCCAATCTACTATCGAG 501 315 238 Antisense
GCAATGGCGTGCTACTGGTTTTCGA 121 321 266 Antisense
ACGGCAGGTCACTCGACAGGATGCG 543 95 408 Antisense
AACATTCGCGTACTCGTTCGACAGA 126 139 536 Antisense
AGAACCACCATCTACGAATCGATCC 84 75 558 Antisense
Sequence Source Affymetrix Proprietary Database