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[189768_at] fatty acid synthase

Description F32H2.5 /REP_DB=WormBase Gene ID /WP=CE09880 /TR=P91871 /GB=CAB04244.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=fatty acid synthase
Cluster 6grp_highest_10_10 > 60      6grp_high1_10_10 > 06      4grp_highest_8_8 > 09      4grp_high_8_8 > 53      6grp_highest_nonorm > 02      6grp_total > 07      4grp_total > 59      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2644
1 2 3 4 range
A 1854.1
(1)
P
2185.8
(2.1)
P
2450.6
(3)
P
631.1
(-3)
P
1820
B 1738.4
(-0)
P
2743.4
(2.9)
P
2782
(3)
P
721.7
(-3)
P
2060
C 1787
(-0.4)
P
3274.9
(3)
P
2792.8
(1.9)
P
656.5
(-3)
P
2618
avr 1793.2
(0.3)
2734.7
(3)
2675.1
(2.8)
669.8
(-3)
2065

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 4849
1 2 3 4 5 6 range
A 3164.2
(3)
P
2813.4
(2)
P
1230.5
(-2.3)
P
1322.9
(-2.1)
P
994.3
(-3)
P
1166.8
(-2.5)
P
2170
B 3624.2
(3)
P
1983.6
(-0.5)
P
1828.3
(-0.8)
P
1361.8
(-1.8)
P
789.4
(-3)
P
827.6
(-2.9)
P
2835
C 5637.9
(3)
P
1984.3
(-1.6)
P
2082.7
(-1.5)
P
1271.4
(-2.5)
P
1343.2
(-2.4)
P
878.9
(-3)
P
4759
avr 4142.1
(3)
2260.4
(-0.5)
1713.8
(-1.6)
1318.7
(-2.3)
1042.3
(-2.8)
957.8
(-3)
3184
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 881
1 2 3 4 range
A 675.1
(3)
P
474.5
(0.9)
P
640.6
(2.6)
P
92.4
(-3)
P
583
B 554.4
(1.6)
P
677.5
(3)
P
644.7
(2.6)
P
153.8
(-3)
P
524
C 591.6
(0.3)
P
941.6
(2.8)
P
973.4
(3)
P
110.7
(-3)
P
863
avr 607
(1.6)
697.9
(2.5)
752.9
(3)
119
(-3)
634

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1834
1 2 3 4 5 6 range
A 583.3
(-0.4)
P
1000.6
(3)
P
268
(-3)
P
335.5
(-2.4)
P
300
(-2.7)
P
284.1
(-2.9)
P
733
B 1261
(3)
P
660.3
(-0.8)
P
444
(-2.1)
P
360.7
(-2.7)
P
320.7
(-2.9)
P
308.6
(-3)
P
952
C 2089.7
(3)
P
605.5
(-1.9)
P
530.1
(-2.1)
P
255.7
(-3)
P
434.6
(-2.4)
P
294.2
(-2.9)
P
1834
avr 1311.3
(3)
755.5
(-0.3)
414
(-2.3)
317.3
(-2.9)
351.8
(-2.7)
295.6
(-3)
1016
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189768_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2535
Sequence Type Exemplar sequence
Representative Public ID F32H2.5 NCBI
Target Description F32H2.5 /REP_DB=WormBase Gene ID /WP=CE09880 /TR=P91871 /GB=CAB04244.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=fatty acid synthase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060016(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_060016 NCBI Caenorhabditis elegans F32H2.5 (F32H2.5) mRNA, complete cds. 11/11 None
SNAP00000013732 ENSEMBL cdna:SNAP chromosome:CEL140:I:8984081:8992895:-1 11/11 None
GENEFINDER00000013770 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:8984081:8992895:-1 11/11 None
F32H2.5 ENSEMBL cdna:known chromosome:CEL140:I:8983508:8992895:-1 gene:F32H2.5 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:8984011-8992826(-) 100.0 100.0
Public Domain and Genome References
Gene Title fatty acid synthase
Ensembl F32H2.5
Entrez Gene 172715 Entrez gene
SwissProt P91871 EMBL-EBI
WormBase CE09880 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.17136.1.S1_AT similar to fatty acid synthase cfa
CANINE_2:CFA.17678.1.S1_S_AT similar to fatty acid synthase cfa
CANINE_2:CFAAFFX.10018.1.S1_S_AT similar to fatty acid synthase cfa
CANINE_2:CFAAFFX.10039.1.S1_S_AT similar to fatty acid synthase cfa
DROSOPHILA_2:1624549_AT dm
DROSGENOME1:152126_AT dm
CHICKEN:GGA.2448.1.S2_AT fatty acid synthase gga
HU35KSUBC:RC_AA058907_F_AT fatty acid synthase hs
HUGENEFL:S80437_S_AT fatty acid synthase hs
U133_X3P:HS.83190.1.S1_3P_A_AT fatty acid synthase hs
U133_X3P:HS.11050.2.A2_3P_S_AT fatty acid synthase hs
HG-U133A_2:212218_S_AT fatty acid synthase hs
HG-FOCUS:212218_S_AT fatty acid synthase hs
HG-U133_PLUS_2:212218_S_AT fatty acid synthase hs
HG-U133A:212218_S_AT fatty acid synthase hs
HG-U95AV2:38429_AT fatty acid synthase hs
MOE430A:1423828_AT fatty acid synthase mm
MOUSE430A_2:1423828_AT fatty acid synthase mm
MOUSE430_2:1423828_AT fatty acid synthase mm
MU11KSUBB:X13135_S_AT fatty acid synthase mm
MG-U74AV2:98575_AT fatty acid synthase mm
MG-U74BV2:110645_AT fatty acid synthase mm
MG-U74BV2:110644_S_AT fatty acid synthase mm
MU19KSUBB:TC33017_AT Fatty acid synthase, mRNA (cDNA clone IMAGE:5699125) mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6633 fatty acid biosynthesis inferred from electronic annotation QuickGO AmiGO
8152 metabolism inferred from electronic annotation QuickGO AmiGO
9058 biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
4024 alcohol dehydrogenase activity, zinc-dependent inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
16740 transferase activity inferred from electronic annotation QuickGO AmiGO
16788 hydrolase activity, acting on ester bonds inferred from electronic annotation QuickGO AmiGO
48037 cofactor binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04244 Hypothetical protein F32H2.5 [Caenorhabditis elegans] ref|NP_492417.1| F32H2.5 [Caenorhabditis elegans] 0.0
blast CAE67008 Hypothetical protein CBG12408 [Caenorhabditis briggsae] 0.0
blast P12276 Fatty acid synthase [Includes: [Acyl-carrier-protein] S-acetyltransferase ; [Acyl-carrier-protein] S-malonyltransferase ; 3-oxoacyl-[acyl-carrier-protein] synthase ; 3-oxoacyl-[acyl-carrier-protein] reductase ; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase ; Enoyl-[acyl-carrier-protein] reductase ; Oleoyl-[acyl-carrier-protein] hydrolase ] gb|AAB46389.1| fatty acid synthase 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001227 EMBL-EBI Acyl transferase domain 1.5E-64
Pfam IPR001031 EMBL-EBI Thioesterase 3.5E-58
Pfam IPR000794 EMBL-EBI Beta-ketoacyl synthase 7.6E-94
Pfam IPR002085 EMBL-EBI Zinc-containing alcohol dehydrogenase superfamily 5.0E-62
Pfam IPR000794 EMBL-EBI Beta-ketoacyl synthase 1.3E-74
Pfam IPR006163 EMBL-EBI Phosphopantetheine-binding domain 1.2E-7
Pfam IPR002085 EMBL-EBI Zinc-containing alcohol dehydrogenase superfamily 5.0E-62
Pfam IPR001227 EMBL-EBI Acyl transferase domain 1.5E-64
Pfam IPR000794 EMBL-EBI Beta-ketoacyl synthase 1.3E-74
Pfam IPR001031 EMBL-EBI Thioesterase 3.5E-58
Pfam IPR006163 EMBL-EBI Phosphopantetheine-binding domain 1.2E-7
Pfam IPR000794 EMBL-EBI Beta-ketoacyl synthase 1.3E-24
Pfam IPR000794 EMBL-EBI Beta-ketoacyl synthase 2.4E-58
Sequence
Target Sequence
>C. ELEGANS:189768_AT
ccatctggaccatatcgtcttgttggatattcttacggagcttgcattggatttgaaatg
gccaatatgcttcaagagtccgacggaagagatgctgttgaacgattgattcttctcgat
ggatcccatctctacatgcaaacttacagaaacgtataccgtatggcctttggagtaacg
ggagattccctggtcaacaatccactcttcgaatctgagatcatgtgtgccatgactctt
cgtttcgccaatgtggattacaagaagttccgatttgaactccttcaacaaccaggattc
aaggcccgtgtgcaaaaggtggtggatcaagtcatgctaactggtctcttcaagtcacca
gagaccgttgcatttgcctgtgaggcaatgcattccaagttcctcatggctgacaagtac
aagccaagaagaaacttcggtggacacatcacactgatcagagctgagcaaggagctgct
cgtgaggaggacgttggagaagattatggagttgcggccgtgtcagaag


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
CCATCTGGACCATATCGTCTTGTTG 535 271 7144 Antisense
TTGATTCTTCTCGATGGATCCCATC 46 707 7249 Antisense
ATCCCATCTCTACATGCAAACTTAC 471 37 7266 Antisense
TCAACAATCCACTCTTCGAATCTGA 271 629 7337 Antisense
ACTCTTCGTTTCGCCAATGTGGATT 97 99 7378 Antisense
CAGGATTCAAGGCCCGTGTGCAAAA 574 207 7436 Antisense
AAGTCATGCTAACTGGTCTCTTCAA 614 157 7472 Antisense
ACCAGAGACCGTTGCATTTGCCTGT 700 85 7500 Antisense
GCATTCCAAGTTCCTCATGGCTGAC 619 307 7533 Antisense
GAAACTTCGGTGGACACATCACACT 229 357 7574 Antisense
TATGGAGTTGCGGCCGTGTCAGAAG 282 655 7648 Antisense
Sequence Source Affymetrix Proprietary Database