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[189765_at] nuclear autoantigen

Description K07C5.8 /REP_DB=WormBase Gene ID /WP=CE06118 /TR=Q17406 /GB=CAA94901.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=nuclear autoantigen
Cluster 6grp_highest_10_10 > 85      6grp_high1_10_10 > 57      4grp_highest_8_8 > 30      4grp_high_8_8 > 06      6grp_highest_nonorm > 90      6grp_total > 58      4grp_total > 03      6grp_highest_sub > Cu      6grp_cgc > 28      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 114
1 2 3 4 range
A 162.2
(-2.7)
P 		155.7
(-3)
P 		208.4
(-0.2)
P 		269.8
(3)
P 		114
B 195.1
(-0.6)
P 		215.2
(0.8)
P 		159.7
(-3)
P 		246.6
(3)
P 		87
C 216.3
(0.8)
P 		174.4
(-3)
P 		196.4
(-1)
P 		241.3
(3)
P 		67
avr 191.2
(-2.2) 		181.8
(-3) 		188.2
(-2.5) 		252.6
(3) 		71

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 157
1 2 3 4 5 6 range
A 149.1
(-1.5)
P 		153.2
(-1.3)
P 		109.2
(-3)
P 		139.9
(-1.8)
P 		154
(-1.3)
P 		266.3
(3)
P 		157
B 179.2
(0.9)
P 		176.3
(0.7)
P 		175.8
(0.7)
P 		121.1
(-3)
P 		137.4
(-1.9)
P 		210.4
(3)
P 		89
C 232.2
(3)
P 		158.8
(-2.4)
P 		159.1
(-2.4)
P 		180.9
(-0.8)
P 		150.4
(-3)
P 		207.7
(1.2)
P 		82
avr 186.8
(-0.1) 		162.8
(-1.8) 		148
(-2.9) 		147.3
(-3) 		147.3
(-3) 		228.1
(3) 		81
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 38
1 2 3 4 range
A 59.1
(3)
P 		33.8
(-3)
P 		54.5
(1.9)
P 		39.5
(-1.6)
P 		25
B 62.2
(3)
P 		53.1
(0.8)
P 		37
(-3)
P 		52.6
(0.7)
P 		25
C 71.6
(3)
P 		50.1
(-1.2)
P 		68.5
(2.4)
P 		40.7
(-3)
P 		31
avr 64.3
(3) 		45.7
(-2.6) 		53.3
(-0.3) 		44.3
(-3) 		20

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 62
1 2 3 4 5 6 range
A 27.5
(-2.5)
P 		54.5
(1.5)
P 		23.8
(-3)
P 		35.5
(-1.3)
P 		46.5
(0.3)
P 		64.8
(3)
P 		41
B 62.4
(0.9)
P 		58.7
(0.4)
P 		42.7
(-1.6)
P 		32.1
(-3)
P 		55.8
(0.1)
P 		78.5
(3)
P 		46
C 86.1
(3)
P 		48.5
(-1.5)
P 		40.5
(-2.5)
P 		36.4
(-3)
P 		48.7
(-1.5)
P 		69.5
(1)
P 		50
avr 58.7
(1) 		53.9
(0.2) 		35.7
(-2.8) 		34.7
(-3) 		50.3
(-0.4) 		70.9
(3) 		36
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189765_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12251
Sequence Type Exemplar sequence
Representative Public ID K07C5.8 NCBI
Target Description K07C5.8 /REP_DB=WormBase Gene ID /WP=CE06118 /TR=Q17406 /GB=CAA94901.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=nuclear autoantigen
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073263(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073263 NCBI Caenorhabditis elegans K07C5.8 (K07C5.8) mRNA, complete cds. 10/11 None
SNAP00000028831 ENSEMBL cdna:SNAP chromosome:CEL140:V:10365735:10367761:1 10/11 None
GENEFINDER00000028844 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10365817:10367761:1 11/11 None
K07C5.8 ENSEMBL cdna:known chromosome:CEL140:V:10364907:10368771:1 gene:K07C5.8 10/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10364906-10367761(+) 100.0 100.0
Public Domain and Genome References
Gene Title nuclear autoantigen
Gene Symbol cash-1
Ensembl K07C5.8
Entrez Gene 179445 Entrez gene
SwissProt Q17406 EMBL-EBI
WormBase CE35585 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CHICKEN:GGAAFFX.23076.1.S1_S_AT similar to Striatin 3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen) gga
MU11KSUBA:AA138853_S_AT striatin, calmodulin binding protein 3 mm
MG-U74AV2:100878_AT striatin, calmodulin binding protein 3 mm
MG-U74BV2:162577_AT striatin, calmodulin binding protein 3 mm
MOE430A:1423535_AT striatin, calmodulin binding protein 3 mm
MOUSE430A_2:1423535_AT striatin, calmodulin binding protein 3 mm
MOUSE430_2:1423535_AT striatin, calmodulin binding protein 3 mm
MOE430A:1423536_AT striatin, calmodulin binding protein 3 mm
MOUSE430A_2:1423536_AT striatin, calmodulin binding protein 3 mm
MOUSE430_2:1423536_AT striatin, calmodulin binding protein 3 mm
MOE430B:1441266_AT Striatin, calmodulin binding protein 3 (Strn3), mRNA mm
MOUSE430_2:1441266_AT Striatin, calmodulin binding protein 3 (Strn3), mRNA mm
MU19KSUBC:TC36769_AT Striatin, calmodulin binding protein 3 (Strn3), mRNA mm
RG-U34C:RC_AI172489_AT striatin, calmodulin binding protein 3 rn
RAE230A:1375537_AT striatin, calmodulin binding protein 3 rn
RAT230_2:1375537_AT striatin, calmodulin binding protein 3 rn
RG-U34A:RC_AA875215_AT Striatin, calmodulin binding protein 3 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4190 aspartic-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94873 Hypothetical protein K07C5.8 [Caenorhabditis elegans] emb|CAA94901.2| Hypothetical protein K07C5.8 [Caenorhabditis elegans] ref|NP_505664.2| K07C5.8 [Caenorhabditis elegans] 0.0
blast CAE64801 Hypothetical protein CBG09594 [Caenorhabditis briggsae] 0.0
blast CAD58749 striatin, calmodulin binding protein 3 [Danio rerio] emb|CAI29388.1| striatin, calmodulin binding protein 3 [Danio rerio] 1.0E-140
Protein Domains
Database ID Description E-Value
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 9.9E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 9.0E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 3.0E-11
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.57
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 8.8E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.0E-4
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 9.9E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 9.0E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 3.0E-11
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.57
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 8.8E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.0E-4
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 9.9E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 9.0E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 3.0E-11
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.57
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 8.8E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.0E-4
Sequence
Target Sequence 
>C. ELEGANS:189765_AT
atctgctgtttcaatgtaccatcttcaaacggggatccatttgattcttatgatccacga
gtcctaactgaaacacttactggacatacggatgcaatttggtcggtggcttatcattca
tcaaacagtcgccttgtttctgccagttctgattcaacggttcgtctatgggaaccagga
aatggtgaaccacttatcagaactattggtgccccaaaatccggaatacttccgacatca
gttgattttgtatctacggaaacatcacatttacttgctgcatacacaaattgctatgct
caaattattgatatcgatactggaagcactgtcatggtgttcgatttcggagcggttaca
ggttcaccaacaatgaacaaaattgttagtcatccaacaatgcctctcacacttattggc
ggtgaagatcggacgattcggtactttgacaacaccaacggatcgataattcatgaagct
atcgcacatgttgagggagtttcttctcttgctattgatccaaatggtctttatcttttg
tctggaagtcatgatggatctgccggtgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCTGCTGTTTCAATGTACCATCTT 509 33 1321 Antisense
GATTCTTATGATCCACGAGTCCTAA 612 431 1363 Antisense
TGGTCGGTGGCTTATCATTCATCAA 61 553 1420 Antisense
TCAAACAGTCGCCTTGTTTCTGCCA 503 629 1441 Antisense
GCCAGTTCTGATTCAACGGTTCGTC 438 279 1462 Antisense
TTGGTGCCCCAAAATCCGGAATACT 532 707 1526 Antisense
GAAACATCACATTTACTTGCTGCAT 203 357 1579 Antisense
GATTTCGGAGCGGTTACAGGTTCAC 501 395 1663 Antisense
AATGCCTCTCACACTTATTGGCGGT 483 167 1719 Antisense
GTTTCTTCTCTTGCTATTGATCCAA 116 451 1819 Antisense
GAAGTCATGATGGATCTGCCGGTGC 541 335 1865 Antisense
Sequence Source Affymetrix Proprietary Database