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[189755_at] epoxide hydrolase

Description W01A11.1 /REP_DB=WormBase Gene ID /WP=CE14390 /TR=Q23068 /GB=AAB04970.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=epoxide hydrolase
Cluster 6grp_highest_10_10 > 26      6grp_high1_10_10 > 40      4grp_highest_8_8 > 34      4grp_high_8_8 > 57      6grp_highest_nonorm > 25      6grp_total > 52      4grp_total > 62      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 851
1 2 3 4 range
A 1693.7
(3)
P 		1472.7
(1.1)
P 		1567
(1.9)
P 		998.4
(-3)
P 		695
B 1619.7
(3)
P 		1142
(-0.7)
P 		1588.1
(2.8)
P 		842.7
(-3)
P 		777
C 1494.1
(2.3)
P 		1133.9
(-2.4)
P 		1544.9
(3)
P 		1090.7
(-3)
P 		454
avr 1602.5
(3) 		1249.5
(-0.4) 		1566.7
(2.7) 		977.3
(-3) 		625

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 4064
1 2 3 4 5 6 range
A 3401.4
(-1.5)
P 		3786.6
(-0.7)
P 		5621
(3)
P 		4771.6
(1.3)
P 		2633.3
(-3)
P 		2736.9
(-2.8)
P 		2988
B 2656.2
(-2.7)
P 		3217.3
(-1.9)
P 		6517.9
(3)
P 		4216
(-0.4)
P 		2578.9
(-2.8)
P 		2453.8
(-3)
P 		4064
C 3015.7
(-2.4)
P 		3593
(-1.5)
P 		6369.8
(3)
P 		4948.2
(0.7)
P 		3268.4
(-2)
P 		2648.4
(-3)
P 		3721
avr 3024.4
(-2.3) 		3532.3
(-1.4) 		6169.6
(3) 		4645.3
(0.4) 		2826.9
(-2.6) 		2613
(-3) 		3557
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 471
1 2 3 4 range
A 616.7
(3)
P 		319.7
(-0.8)
P 		409.7
(0.4)
P 		146.1
(-3)
P 		471
B 516.5
(3)
P 		282
(-1.2)
P 		368
(0.4)
P 		179.6
(-3)
P 		337
C 494.6
(2.3)
P 		326
(-0.6)
P 		538.4
(3)
P 		183.9
(-3)
P 		355
avr 542.6
(3) 		309.2
(-0.8) 		438.7
(1.3) 		169.9
(-3) 		373

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 994
1 2 3 4 5 6 range
A 627
(-3)
P 		1346.7
(3)
P 		1224.1
(2)
P 		1210.2
(1.9)
P 		794.6
(-1.6)
P 		666.4
(-2.7)
P 		720
B 924.2
(-2.9)
P 		1070.9
(-1.6)
P 		1582.8
(3)
P 		1116.7
(-1.2)
P 		1047.8
(-1.8)
P 		915
(-3)
P 		668
C 1117.8
(-1.1)
P 		1096.3
(-1.3)
P 		1621.2
(3)
P 		995.1
(-2.1)
P 		1057.6
(-1.6)
P 		886.6
(-3)
P 		735
avr 889.7
(-2.4) 		1171.3
(0.2) 		1476
(3) 		1107.3
(-0.4) 		966.7
(-1.7) 		822.7
(-3) 		653
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189755_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11884
Sequence Type Exemplar sequence
Representative Public ID W01A11.1 NCBI
Target Description W01A11.1 /REP_DB=WormBase Gene ID /WP=CE14390 /TR=Q23068 /GB=AAB04970.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=epoxide hydrolase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072249(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072249 NCBI Caenorhabditis elegans W01A11.1 (W01A11.1) mRNA, complete cds. 11/11 None
SNAP00000000915 ENSEMBL cdna:SNAP chromosome:CEL140:V:6501818:6504959:1 11/11 None
GENEFINDER00000000920 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:6499704:6504959:1 11/11 None
W01A11.1.1 ENSEMBL cdna:known chromosome:CEL140:V:6501817:6505019:1 gene:W01A11.1 11/11 None
W01A11.1.2 ENSEMBL cdna:known chromosome:CEL140:V:6501818:6504960:1 gene:W01A11.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:6501817-6504959(+) 100.0 100.0
Public Domain and Genome References
Gene Title epoxide hydrolase
Ensembl W01A11.1
Entrez Gene 179036 Entrez gene
SwissProt Q23068 EMBL-EBI
WormBase CE14390 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1586332_AT similar to Epoxide hydrolase 1 (Microsomal epoxide hydrolase) (Epoxide hydratase) cfa
CANINE_2:CFA.4088.1.A1_AT similar to Epoxide hydrolase 1 (Microsomal epoxide hydrolase) (Epoxide hydratase) cfa
CANINE_2:CFA.4088.1.A1_S_AT similar to Epoxide hydrolase 1 (Microsomal epoxide hydrolase) (Epoxide hydratase) cfa
CANINE_2:CFAAFFX.24797.1.S1_AT similar to Epoxide hydrolase 1 (Microsomal epoxide hydrolase) (Epoxide hydratase) cfa
DROSOPHILA_2:1626414_AT Juvenile hormone epoxide hydrolase 1 dm
DROSGENOME1:142196_AT Juvenile hormone epoxide hydrolase 1 dm
CHICKEN:GGA.4674.3.S1_AT similar to Epoxide hydrolase 1 (Microsomal epoxide hydrolase) (Epoxide hydratase) gga
HG-U133A:202017_AT epoxide hydrolase 1, microsomal (xenobiotic) hs
HG-U133_PLUS_2:202017_AT epoxide hydrolase 1, microsomal (xenobiotic) hs
HG-FOCUS:202017_AT epoxide hydrolase 1, microsomal (xenobiotic) hs
HG-U133A_2:202017_AT epoxide hydrolase 1, microsomal (xenobiotic) hs
HU35KSUBA:L25880_S_AT epoxide hydrolase 1, microsomal (xenobiotic) hs
HUGENEFL:L25878_S_AT epoxide hydrolase 1, microsomal (xenobiotic) hs
U133_X3P:G4557560_3P_AT epoxide hydrolase 1, microsomal (xenobiotic) hs
HG-U95AV2:38790_AT epoxide hydrolase 1, microsomal (xenobiotic) hs
HG-U95C:59694_AT epoxide hydrolase 1, microsomal (xenobiotic) hs
HG-U95D:71322_AT Epoxide hydrolase 1, microsomal (xenobiotic) hs
MG-U74AV2:101587_AT epoxide hydrolase 1, microsomal mm
MOE430A:1422438_AT epoxide hydrolase 1, microsomal mm
MOUSE430A_2:1422438_AT epoxide hydrolase 1, microsomal mm
MOUSE430_2:1422438_AT epoxide hydrolase 1, microsomal mm
MU19KSUBB:TC33651_AT Epoxide hydrolase 1, microsomal, mRNA (cDNA clone MGC:30577 IMAGE:3491966) mm
RT-U34:M26125_AT epoxide hydrolase 1 rn
RG-U34A:M26125_AT epoxide hydrolase 1 rn
RAE230A:1387669_A_AT epoxide hydrolase 1 rn
RAT230_2:1387669_A_AT epoxide hydrolase 1 rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB04970 Hypothetical protein W01A11.1 [Caenorhabditis elegans] ref|NP_504650.1| W01A11.1 [Caenorhabditis elegans] 0.0
blast CAE71892 Hypothetical protein CBG18950 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR010497 EMBL-EBI Epoxide hydrolase, N-terminal 2.2E-67
Pfam IPR010497 EMBL-EBI Epoxide hydrolase, N-terminal 2.2E-67
Pfam IPR007130 EMBL-EBI Diacylglycerol acyltransferase 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000000920 3 41-63,68-85,368-390
Sequence
Target Sequence 
>C. ELEGANS:189755_AT
tgacatcctcggttggcttattccatctactctttcatcgaaagaaattcaaaaaactca
caatccattctcaaagttcggacttttgattgtcgagacaggctacatgcatcttcaagc
aacaaaaccagatactgcaggaacttccttgaatgattctccaattggtcttgctgcata
catcattgaaaagttctcaacatggaccaacacagaaaaccgtgcacttcctgatggtgg
tcttaacaaaagatttacaaatgatgaacttctcactattgttatgatctactggaccaa
tggaaacattgtctcttcgcagagattctacagagaaatgttcctcgaccgtagatgcga
ggcacttggaaaacgatatgtgtcaactccaactgcacatgccagcggcctcaacgagct
ctatgaccgtacaccaatcgaggtctcccgtcattcctataacatcacccattatactga
aatcgatatgggacactttgccgcgtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGACATCCTCGGTTGGCTTATTCCA 159 571 807 Antisense
TTATTCCATCTACTCTTTCATCGAA 45 679 824 Antisense
GACAGGCTACATGCATCTTCAAGCA 383 369 903 Antisense
AACCAGATACTGCAGGAACTTCCTT 148 149 932 Antisense
GATTCTCCAATTGGTCTTGCTGCAT 148 433 961 Antisense
AGAAAACCGTGCACTTCCTGATGGT 601 71 1020 Antisense
ATGGAAACATTGTCTCTTCGCAGAG 295 53 1106 Antisense
AGAAATGTTCCTCGACCGTAGATGC 590 71 1140 Antisense
GCCTCAACGAGCTCTATGACCGTAC 709 279 1214 Antisense
GACCGTACACCAATCGAGGTCTCCC 269 383 1231 Antisense
TCGATATGGGACACTTTGCCGCGTT 667 595 1289 Antisense
Sequence Source Affymetrix Proprietary Database