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[189750_s_at] adenylate kinase

Description ZK673.2 /REP_DB=WormBase Gene ID /WP=CE01714 /TR=SW:Q09629 /GB=CAA88479.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=adenylate kinase
Cluster 6grp_highest_10_10 > 48      6grp_high1_10_10 > 73      4grp_highest_8_8 > 31      4grp_high_8_8 > 05      6grp_highest_nonorm > 55      6grp_total > 73      4grp_total > 03      6grp_high1_sub > 03_04      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5609
1 2 3 4 range
A 1861.5
(-2)
P 		1246.2
(-2.7)
P 		1009.7
(-3)
P 		5884.2
(3)
P 		4875
B 1825.8
(-2.2)
P 		1458
(-2.6)
P 		1108.6
(-3)
P 		6618.9
(3)
P 		5510
C 1984.1
(-1.6)
P 		1361.6
(-2.6)
P 		1137.1
(-3)
P 		4740.3
(3)
P 		3603
avr 1890.5
(-2) 		1355.3
(-2.7) 		1085.1
(-3) 		5747.8
(3) 		4663

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1118
1 2 3 4 5 6 range
A 1261.4
(-3)
P 		1706.8
(0.8)
P 		1968.9
(3)
P 		1763.5
(1.3)
P 		1689.5
(0.6)
P 		1515.7
(-0.8)
P 		708
B 1454.9
(-3)
P 		1595.4
(-2.1)
P 		2271.9
(2.3)
P 		1782.2
(-0.9)
P 		2379.1
(3)
P 		1869.8
(-0.3)
P 		924
C 1434.4
(-3)
P 		1525.1
(-2)
P 		1694.1
(-0.2)
P 		1923.8
(2.3)
P 		1737.5
(0.3)
P 		1985.5
(3)
P 		551
avr 1383.6
(-3) 		1609.1
(-0.7) 		1978.3
(3) 		1823.2
(1.4) 		1935.4
(2.6) 		1790.3
(1.1) 		595
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1154
1 2 3 4 range
A 677.8
(1.2)
P 		270.5
(-2.9)
P 		264
(-3)
P 		861.3
(3)
P 		597
B 582.2
(-1.3)
P 		360.1
(-2.5)
P 		256.9
(-3)
P 		1410.5
(3)
P 		1154
C 656.8
(0.9)
P 		391.5
(-3)
P 		396.3
(-2.9)
P 		799.3
(3)
P 		408
avr 638.9
(-0.2) 		340.7
(-2.7) 		305.7
(-3) 		1023.7
(3) 		718

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 734
1 2 3 4 5 6 range
A 232.5
(-3)
P 		607
(3)
P 		428.8
(0.1)
P 		447.3
(0.4)
P 		509.8
(1.4)
P 		369
(-0.8)
P 		375
B 506.2
(-2.6)
P 		531
(-2.3)
P 		551.7
(-2)
P 		472.1
(-3)
P 		966.6
(3)
P 		697.2
(-0.3)
P 		495
C 531.7
(0.1)
P 		465.3
(-1.3)
P 		431.2
(-2)
P 		386.9
(-3)
P 		562.2
(0.8)
P 		664.7
(3)
P 		278
avr 423.5
(-3) 		534.4
(-0.4) 		470.6
(-1.9) 		435.4
(-2.7) 		679.5
(3) 		577
(0.6) 		256
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189750_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2729
Sequence Type Exemplar sequence
Representative Public ID ZK673.2 NCBI
Target Description ZK673.2 /REP_DB=WormBase Gene ID /WP=CE01714 /TR=SW:Q09629 /GB=CAA88479.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=adenylate kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063844(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063844 NCBI Caenorhabditis elegans ZK673.2 (ZK673.2) mRNA, complete cds. 11/11 None
SNAP00000007624 ENSEMBL cdna:SNAP chromosome:CEL140:II:10448187:10449783:1 11/11 None
GENEFINDER00000007637 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:10443250:10449783:1 11/11 None
ZK673.2.2 ENSEMBL cdna:known chromosome:CEL140:II:10448171:10450116:1 gene:ZK673.2 11/11 None
ZK673.2.1 ENSEMBL cdna:known chromosome:CEL140:II:10448176:10450122:1 gene:ZK673.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:10448183-10449780(+) 100.0 100.0
Public Domain and Genome References
Gene Title adenylate kinase
Ensembl ZK673.2
Entrez Gene 174608 Entrez gene
SwissProt Q09629 EMBL-EBI
WormBase CE01714 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.21226.1.S1_S_AT similar to adenylate kinase 3 cfa
CANINE_2:CFAAFFX.21229.1.S1_S_AT similar to adenylate kinase 3 cfa
CANINE_2:CFAAFFX.4041.1.S1_S_AT similar to adenylate kinase 3 cfa
CANINE_2:CFAAFFX.4181.1.S1_S_AT similar to adenylate kinase 3 cfa
DROSOPHILA_2:1630986_S_AT Adenylate kinase-3 dm
DROSGENOME1:142703_AT Adenylate kinase-3 dm
HG-U133_PLUS_2:224151_S_AT adenylate kinase 3 hs
HG-U133B:224151_S_AT adenylate kinase 3 hs
HU35KSUBA:HUM_ALU_AT adenylate kinase 3 hs
HU35KSUBB:HUM_ALU_AT adenylate kinase 3 hs
HU35KSUBC:HUM_ALU_AT adenylate kinase 3 hs
HU35KSUBD:HUM_ALU_AT adenylate kinase 3 hs
HUGENEFL:HUM_ALU_AT adenylate kinase 3 hs
HC-G110:HUM_ALU_AT adenylate kinase 3 hs
HU35KSUBA:AA476639_AT adenylate kinase 3 hs
HU35KSUBC:RC_N73807_AT adenylate kinase 3 hs
HU35KSUBC:RC_N23736_AT adenylate kinase 3 hs
HU35KSUBD:RC_R70790_AT adenylate kinase 3 hs
U133_X3P:G9963776_3P_A_AT adenylate kinase 3 hs
U133_X3P:HS.43436.1.S3_3P_X_AT adenylate kinase 3 hs
U133_X3P:HS.43436.1.S3_3P_AT adenylate kinase 3 hs
HG-U133_PLUS_2:224655_AT adenylate kinase 3 hs
HG-U133B:224655_AT adenylate kinase 3 hs
HG-U95B:45084_AT adenylate kinase 3 hs
HG-U95C:49054_AT adenylate kinase 3 hs
HG-U95B:44316_AT Adenylate kinase 3 hs
HG-U95E:69856_AT Adenylate kinase 3 hs
MOUSE430A_2:1432436_A_AT adenylate kinase 3 mm
MOUSE430_2:1432436_A_AT adenylate kinase 3 mm
MOE430A:1432436_A_AT adenylate kinase 3 mm
MU11KSUBB:MSA.40192.0_S_AT adenylate kinase 3 mm
MG-U74AV2:92492_AT adenylate kinase 3 mm
MG-U74AV2:160233_AT adenylate kinase 3 mm
MG-U74BV2:164931_R_AT adenylate kinase 3 mm
MOE430A:1423717_AT adenylate kinase 3 mm
MOUSE430A_2:1423717_AT adenylate kinase 3 mm
MOUSE430_2:1423717_AT adenylate kinase 3 mm
MOE430A:1423718_AT adenylate kinase 3 mm
MOUSE430A_2:1423718_AT adenylate kinase 3 mm
MOUSE430_2:1423718_AT adenylate kinase 3 mm
MOUSE430_2:1458812_AT Adenylate kinase 3 (Ak3), mRNA mm
MOE430B:1458812_AT Adenylate kinase 3 (Ak3), mRNA mm
MU19KSUBC:TC37214_AT Adenylate kinase 3 (Ak3), mRNA mm
MU19KSUBC:TC37214_G_AT Adenylate kinase 3 (Ak3), mRNA mm
RG-U34A:RC_AI176052_AT adenylate kinase 3 rn
RAE230A:1368095_AT adenylate kinase 3 rn
RAT230_2:1368095_AT adenylate kinase 3 rn
RAE230A:1375577_AT Adenylate kinase 3 rn
RAT230_2:1375577_AT Adenylate kinase 3 rn
RAE230A:1377160_AT Adenylate kinase 3 rn
RAT230_2:1377160_AT Adenylate kinase 3 rn
RAE230B:1383733_AT Adenylate kinase 3 rn
RAT230_2:1383733_AT Adenylate kinase 3 rn
RAE230A:1388558_AT Adenylate kinase 3 rn
RAT230_2:1388558_AT Adenylate kinase 3 rn
RG-U34C:RC_AI171802_AT Adenylate kinase 3 rn
YEAST_2:1771081_AT Mitochondrial adenylate kinase, catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background Sc
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4017 adenylate kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88479 Hypothetical protein ZK673.2 [Caenorhabditis elegans] ref|NP_496245.1| ZK673.2 [Caenorhabditis elegans] sp|Q09629|KADY_CAEEL Probable adenylate kinase isoenzyme ZK673.2 (ATP-AMP transphosphorylase) 1.0E-122
blast CAA88479 Hypothetical protein ZK673.2 [Caenorhabditis elegans] ref|NP_496245.1| ZK673.2 [Caenorhabditis elegans] sp|Q09629|KADY_CAEEL Probable adenylate kinase isoenzyme ZK673.2 (ATP-AMP transphosphorylase) 1.0E-121
blast CAE59681 Hypothetical protein CBG03104 [Caenorhabditis briggsae] 1.0E-119
Protein Domains
Database ID Description E-Value
Pfam IPR000850 EMBL-EBI Adenylate kinase 1.2E-36
Pfam IPR007862 EMBL-EBI Adenylate kinase, lid region 3.7E-15
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 6.1E-16
Pfam IPR000850 EMBL-EBI Adenylate kinase 1.2E-36
Pfam IPR007862 EMBL-EBI Adenylate kinase, lid region 3.7E-15
Sequence
Target Sequence 
>C. ELEGANS:189750_S_AT
tgctcgtgcgagaattcgaacccctaggattcaattatttcgctgctggagactttattc
gcgatcatattgccagagggacagaattcggagttcgtgcacaatcgttcctcaacaagg
gcgagcacgttccagacagtattctgaacggagccatactggcggagatgcttaaagcag
gaccacgtgtcgttctcgacggatatccacgaaacatgagccagctgaaaatggttgaag
agcaggcgccgttgaatttgatcgttgaattgaaggttcctcgcaaagtgctcatcgatc
gtttgtcaaagcaattggtgcatccagcatccggaagagcatacaatttggaagtgaatc
caccaaaggaggagggcaaagacgatatcacgggagagccactgttcaagcgaagcacgg
atcagttggaggtggcaagaaggaggcttgaggtttacgataagacagaaaacaaggtgt
tggactattataagaagcaaaacaagtgcatcacaatgtctggtgaatcatcgaaagccg
tattcgagtcggttgccga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGCTCGTGCGAGAATTCGAACCCCT 178 581 71 Antisense
GCTGCTGGAGACTTTATTCGCGATC 283 297 112 Antisense
TCGGAGTTCGTGCACAATCGTTCCT 351 605 158 Antisense
TCAACAAGGGCGAGCACGTTCCAGA 507 629 182 Antisense
TAAAGCAGGACCACGTGTCGTTCTC 494 637 243 Antisense
TGTCGTTCTCGACGGATATCCACGA 42 559 258 Antisense
GAGCAGGCGCCGTTGAATTTGATCG 549 389 310 Antisense
GTTCCTCGCAAAGTGCTCATCGATC 540 551 346 Antisense
CAATTGGTGCATCCAGCATCCGGAA 604 179 382 Antisense
GGGAGAGCCACTGTTCAAGCGAAGC 292 487 462 Antisense
AAGCCGTATTCGAGTCGGTTGCCGA 537 147 605 Antisense
Sequence Source Affymetrix Proprietary Database