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[189749_s_at] GTP-binding protein

Description F46B6.4 /REP_DB=WormBase Gene ID /WP=CE05870 /TR=Q20446 /GB=CAA94821.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=GTP-binding protein
Cluster 6grp_highest_10_10 > 98      6grp_high1_10_10 > 89      4grp_highest_8_8 > 37      4grp_high_8_8 > 01      6grp_highest_nonorm > 73      6grp_total > 59      4grp_total > 07      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 386
1 2 3 4 range
A 644.1
(-0.4)
P 		473.5
(-3)
P 		593.1
(-1.1)
P 		859.9
(3)
P 		386
B 706.1
(3)
P 		570.7
(-0.7)
P 		595.7
(-0.1)
P 		489.3
(-3)
P 		217
C 682.3
(3)
P 		526.4
(-3)
P 		592.8
(-0.4)
P 		681.4
(3)
P 		156
avr 677.5
(3) 		523.5
(-3) 		593.9
(-0.3) 		676.9
(3) 		154

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 246
1 2 3 4 5 6 range
A 665.4
(3)
P 		456.2
(-2.1)
P 		419
(-3)
P 		553.8
(0.3)
P 		517.6
(-0.6)
P 		640.2
(2.4)
P 		246
B 582.4
(0.6)
P 		533.8
(-0.9)
P 		504.7
(-1.8)
P 		466.5
(-3)
P 		657.5
(3)
P 		591.1
(0.9)
P 		191
C 483.4
(-2.1)
P 		455.3
(-3)
P 		593.8
(1.7)
P 		465.1
(-2.7)
P 		619
(2.5)
P 		632.9
(3)
P 		178
avr 577.1
(1.1) 		481.8
(-3) 		505.8
(-2) 		495.1
(-2.4) 		598
(2) 		621.4
(3) 		140
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 132
1 2 3 4 range
A 234.5
(3)
P 		102.8
(-3)
P 		155.1
(-0.6)
P 		125.9
(-1.9)
P 		132
B 225.2
(3)
P 		141
(-1.2)
P 		138
(-1.3)
P 		104.3
(-3)
P 		121
C 225.8
(3)
P 		151.3
(-1)
P 		206.6
(2)
P 		114.9
(-3)
P 		111
avr 228.5
(3) 		131.7
(-2.1) 		166.6
(-0.3) 		115
(-3) 		114

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 176
1 2 3 4 5 6 range
A 122.7
(-0.3)
P 		162.2
(3)
P 		91.2
(-3)
P 		140.5
(1.2)
P 		156.2
(2.5)
P 		155.9
(2.5)
P 		71
B 202.7
(0.3)
P 		177.7
(-0.7)
P 		122.5
(-3)
P 		123.6
(-3)
P 		267.2
(3)
P 		220.4
(1.1)
P 		145
C 179.2
(1.3)
P 		138.9
(-0.7)
P 		151.1
(-0.1)
P 		93.5
(-3)
P 		200.3
(2.4)
P 		211.9
(3)
P 		118
avr 168.2
(0.3) 		159.6
(-0.3) 		121.6
(-2.8) 		119.2
(-3) 		207.9
(3) 		196.1
(2.2) 		89
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189749_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11391
Sequence Type Exemplar sequence
Representative Public ID F46B6.4 NCBI
Target Description F46B6.4 /REP_DB=WormBase Gene ID /WP=CE05870 /TR=Q20446 /GB=CAA94821.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=GTP-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073122(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073122 NCBI Caenorhabditis elegans F46B6.4 (F46B6.4) mRNA, complete cds. 11/11 None
SNAP00000041197 ENSEMBL cdna:SNAP chromosome:CEL140:V:9780467:9785625:-1 11/11 None
GENEFINDER00000041207 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:9777576:9782099:-1 11/11 None
F46B6.4 ENSEMBL cdna:known chromosome:CEL140:V:9780467:9782099:-1 gene:F46B6.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:9780466-9782099(-) 99.64 100.0
Public Domain and Genome References
Gene Title GTP-binding protein
Ensembl F46B6.4
Entrez Gene 179372 Entrez gene
SwissProt Q20446 EMBL-EBI
WormBase CE05870 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:247891_AT GTP-binding family protein at
CANINE_2:CFAAFFX.17078.1.S1_AT similar to pseudoautosomal GTP-binding protein-like protein cfa
DROSOPHILA_2:1628971_AT dm
DROSGENOME1:150591_AT dm
CHICKEN:GGAAFFX.10694.1.S1_AT similar to pseudoautosomal GTP-binding protein-like protein gga
MG-U74BV2:164439_F_AT GTP binding protein 6 (putative) mm
MG-U74CV2:171161_I_AT GTP binding protein 6 (putative) mm
MOE430A:1427350_A_AT GTP binding protein 6 (putative) mm
MOUSE430A_2:1427350_A_AT GTP binding protein 6 (putative) mm
MOUSE430_2:1427350_A_AT GTP binding protein 6 (putative) mm
MU19KSUBB:TC29742_AT GTP binding protein 6 (putative) (Gtpbp6), mRNA mm
RG-U34B:RC_AI012210_AT similar to Pseudoautosomal GTP-binding protein-like protein (predicted) rn
RG-U34C:RC_AI145384_AT similar to Pseudoautosomal GTP-binding protein-like protein (predicted) rn
RG-U34C:RC_AI145384_G_AT similar to Pseudoautosomal GTP-binding protein-like protein (predicted) rn
RAE230B:1393325_AT similar to Pseudoautosomal GTP-binding protein-like protein (predicted) rn
RAT230_2:1393325_AT similar to Pseudoautosomal GTP-binding protein-like protein (predicted) rn
RAE230B:1393326_S_AT similar to Pseudoautosomal GTP-binding protein-like protein (predicted) rn
RAT230_2:1393326_S_AT similar to Pseudoautosomal GTP-binding protein-like protein (predicted) rn
RAE230B:1393102_AT similar to Pseudoautosomal GTP-binding protein-like protein (predicted) rn
RAT230_2:1393102_AT similar to Pseudoautosomal GTP-binding protein-like protein (predicted) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94821 Hypothetical protein F46B6.4 [Caenorhabditis elegans] ref|NP_505523.1| F46B6.4 [Caenorhabditis elegans] 0.0
blast CAE72253 Hypothetical protein CBG19372 [Caenorhabditis briggsae] 0.0
blast CAA94828 Hypothetical protein F46B6.5a [Caenorhabditis elegans] ref|NP_505524.2| F46B6.5a [Caenorhabditis elegans] 0.0
blast CAD54137 Hypothetical protein F46B6.5b [Caenorhabditis elegans] ref|NP_872162.2| F46B6.5b [Caenorhabditis elegans] 0.0
blast CAD91633 Hypothetical protein F46B6.5c [Caenorhabditis elegans] ref|NP_001023935.1| F46B6.5c [Caenorhabditis elegans] 0.0
blast CAD18872 Hypothetical protein F46B6.3b [Caenorhabditis elegans] ref|NP_741600.1| Suppressor with Morphological effect on Genitalia family member (smg-4) [Caenorhabditis elegans] 1.0E-164
Protein Domains
Database ID Description E-Value
Pfam IPR005120 EMBL-EBI Smg-4/UPF3 4.2E-103
Pfam IPR008584 EMBL-EBI Eukaryotic protein of unknown function DUF866 1.1E-58
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000041207 1 478-500
Sequence
Target Sequence 
>C. ELEGANS:189749_S_AT
ggatcagttgtttgccacattggacaccacacgccacttggcaaagttaccttctggtcg
atcagctgtgtttactgatacaatcggatttttgagcgatttgccaatgcatttgattgc
ggcattcgaagctacgctggctcatgtgaaatctgcggatgtgataatccaccttcgaga
catttccaatccggactggaaagcacaagaagaagatgttctggcaacacttaaatccat
tggagttacagattatgtactcaacgaaaggataatttctgttgataacaagatcgacaa
agaatctgcatttcccacttccgaatcaaacaattccgtacgaatttcgtgtaaaacagg
tgatggtatgcatgaactcattgatgttatcaacgataaagttacaatggttacaaagtg
caaaacgattcgacttcgtctggatgctcgatcaccagtaattgaatggctttatcataa
cgaattagtggtcattgagcccaccatcg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGATCAGTTGTTTGCCACATTGGAC 319 511 801 Antisense
ACACCACACGCCACTTGGCAAAGTT 593 109 824 Antisense
AAGTTACCTTCTGGTCGATCAGCTG 664 155 844 Antisense
GATTGCGGCATTCGAAGCTACGCTG 203 433 915 Antisense
GAAGCTACGCTGGCTCATGTGAAAT 134 343 928 Antisense
GATAATCCACCTTCGAGACATTTCC 14 423 963 Antisense
TCGAGACATTTCCAATCCGGACTGG 547 601 975 Antisense
CATTTCCCACTTCCGAATCAAACAA 154 215 1109 Antisense
GATTCGACTTCGTCTGGATGCTCGA 181 433 1227 Antisense
GATGCTCGATCACCAGTAATTGAAT 537 413 1243 Antisense
TTAGTGGTCATTGAGCCCACCATCG 615 681 1285 Antisense
Sequence Source Affymetrix Proprietary Database