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[189744_s_at] aldose 1-epimerase /// ---

Description C01B4.6 /REP_DB=WormBase Gene ID /WP=CE20475 /TR=Q9UAT6 /GB=AAD14698.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=aldose 1-epimerase
Cluster 6grp_high1_10_10 > 19      6grp_total > 02      4grp_total > 63      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 173
1 2 3 4 range
A 216.7
(3)
P 		93.3
(-3)
M 		200.1
(2.2)
P 		174.5
(0.9)
P 		123
B 142.9
(-1.2)
P 		161.8
(3)
M 		135.7
(-2.9)
M 		135.1
(-3)
P 		27
C 125.2
(2)
A 		117.6
(1.5)
M 		141.1
(3)
P 		44.2
(-3)
A 		97
avr 161.6
(3) 		124.2
(-2.1) 		159
(2.6) 		117.9
(-3) 		44

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 245
1 2 3 4 5 6 range
A 107.8
(-2)
P 		276.2
(3)
P 		176.3
(0)
P 		149.7
(-0.8)
M 		99
(-2.3)
A 		74.4
(-3)
P 		202
B 139.1
(-2.8)
M 		218
(3)
P 		136.9
(-3)
P 		139
(-2.8)
P 		166.8
(-0.8)
P 		178.1
(0)
P 		81
C 311.2
(2.8)
P 		215
(-0.1)
P 		205.8
(-0.3)
P 		114.8
(-3)
A 		319.7
(3)
P 		123.9
(-2.7)
P 		205
avr 186
(0.3) 		236.4
(3) 		173
(-0.4) 		134.5
(-2.5) 		195.2
(0.8) 		125.5
(-3) 		111
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 72
1 2 3 4 range
A 78.9
(3)
P 		20.2
(-3)
M 		52.3
(0.3)
P 		25.5
(-2.5)
P 		59
B 45.6
(3)
P 		40
(1)
M 		31.4
(-2.1)
M 		28.8
(-3)
P 		17
C 41.4
(1.9)
A 		33.8
(0.8)
M 		49.2
(3)
P 		7.4
(-3)
A 		42
avr 55.3
(3) 		31.3
(-1.1) 		44.3
(1.1) 		20.6
(-3) 		35

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 97
1 2 3 4 5 6 range
A 19.9
(-2.9)
P 		98.2
(3)
P 		38.4
(-1.5)
P 		38
(-1.5)
M 		29.9
(-2.1)
A 		18.1
(-3)
P 		80
B 48.4
(-0.7)
M 		72.5
(3)
P 		33.3
(-3)
P 		36.8
(-2.5)
P 		67.8
(2.3)
P 		66.4
(2.1)
P 		39
C 115.4
(3)
P 		65.6
(-0.2)
P 		52.4
(-1.1)
P 		23.1
(-3)
A 		103.4
(2.2)
P 		41.5
(-1.8)
P 		92
avr 61.2
(0.7) 		78.8
(3) 		41.4
(-1.9) 		32.6
(-3) 		67
(1.5) 		42
(-1.8) 		46
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189744_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14991
Sequence Type Exemplar sequence
Representative Public ID C01B4.6 NCBI
Target Description C01B4.6 /REP_DB=WormBase Gene ID /WP=CE20475 /TR=Q9UAT6 /GB=AAD14698.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=aldose 1-epimerase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071256(11), NM_071283(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071256 NCBI Caenorhabditis elegans Y19D10A.4 (Y19D10A.4) mRNA, complete cds. 11/11 A 
NM_071283 NCBI Caenorhabditis elegans C01B4.6 (C01B4.6) mRNA, complete cds. 11/11 A 
SNAP00000008433 ENSEMBL cdna:SNAP chromosome:CEL140:V:2500879:2503295:1 11/11 None
GENEFINDER00000008437 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:2494063:2513096:1 11/11 None
SNAP00000029974 ENSEMBL cdna:SNAP chromosome:CEL140:V:2392600:2395016:1 11/11 None
GENEFINDER00000029978 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:2385784:2404817:1 11/11 None
Y19D10A.4 ENSEMBL cdna:known chromosome:CEL140:V:2385784:2393975:1 gene:Y19D10A.4 11/11 A 
C01B4.6 ENSEMBL cdna:known chromosome:CEL140:V:2500879:2502254:1 gene:C01B4.6 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:2392599-2393975(+) 100.0 100.0
chrV:2500878-2502254(+) 100.0 100.0
Public Domain and Genome References
Gene Title aldose 1-epimerase

Ensembl Y19D10A.4
C01B4.6
Entrez Gene 178718 Entrez gene
178723 Entrez gene
SwissProt Q9UAT6 EMBL-EBI
Q966D4 EMBL-EBI
WormBase CE20475 Wormbase
CE21450 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1636453_AT dm
DROSGENOME1:146248_AT dm
DROSOPHILA_2:1636453_AT dm
DROSGENOME1:146248_AT dm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6012 galactose metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4034 aldose 1-epimerase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_503657 Y19D10A.4 [Caenorhabditis elegans] gb|AAK68417.1| Hypothetical protein Y19D10A.4 [Caenorhabditis elegans] 0.0
blast AAD14699 Hypothetical protein C01B4.7 [Caenorhabditis elegans] ref|NP_503683.1| C01B4.7 [Caenorhabditis elegans] 0.0
blast CAE58098 Hypothetical protein CBG01182 [Caenorhabditis briggsae] 0.0
blast AAD14695 Seven tm receptor protein 258 [Caenorhabditis elegans] ref|NP_503686.1| Seven TM Receptor family member (str-258) [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR008183 EMBL-EBI Aldose 1-epimerase 2.0E-113
Pfam IPR008183 EMBL-EBI Aldose 1-epimerase 2.0E-113
Pfam IPR003002 EMBL-EBI 7TM chemoreceptor, subfamily 1 4.7E-9
Pfam IPR008183 EMBL-EBI Aldose 1-epimerase 2.0E-113
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_503657.1 12 39-61,92-114,119-141,151-173,180-202,212-231,272-294,309-328,341-363,367-389,402-424,434-456
Y19D10A.4 12 39-61,92-114,119-141,151-173,180-202,212-231,272-294,309-328,341-363,367-389,402-424,434-456
GENEFINDER00000008437 25 39-61,92-114,119-141,151-173,180-202,212-231,272-294,309-328,341-363,367-389,402-424,955-977,989-1011,1039-1061,1082-1099,1134-1156,1184-1206,1278-1300,1378-1400,1413-1430,1459-1481,1501-1523,1575-1597,1628-1650,1657-1679
GENEFINDER00000029978 25 39-61,92-114,119-141,151-173,180-202,212-231,272-294,309-328,341-363,367-389,402-424,955-977,989-1011,1039-1061,1082-1099,1134-1156,1184-1206,1278-1300,1378-1400,1413-1430,1459-1481,1501-1523,1575-1597,1628-1650,1657-1679
Sequence
Target Sequence 
>C. ELEGANS:189744_S_AT
ggcttcctggcgatgcgaaaattgatgtaacctacactgtaaatgaccgtaaccagctca
tcatcgagcaccacgcgacatgcgacaccccgggcctgctcgctctcaccaatcacgcct
actggaacctagacggctcggataccgtcgccgagcactttctggagatggaagccgacg
agttcgtggaggtggacgatacgttctgcccaactggagccatccgatccgtcaccgaca
ccggattcgattttcggagtgggaagcagctgaaagagtcggggaaggacgcggaggagt
tgctggatttggataatgatttagtgatcactaagaagaccccgccatcaactccatcga
cttacttgagattttggagc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGCTTCCTGGCGATGCGAAAATTGA 689 537 386 Antisense
ATGCGAAAATTGATGTAACCTACAC 430 35 398 Antisense
GTAACCTACACTGTAAATGACCGTA 367 423 412 Antisense
AAATGACCGTAACCAGCTCATCATC 595 119 426 Antisense
TAACCAGCTCATCATCGAGCACCAC 461 635 435 Antisense
CCAATCACGCCTACTGGAACCTAGA 366 277 494 Antisense
GCCTACTGGAACCTAGACGGCTCGG 708 277 502 Antisense
GTTGCTGGATTTGGATAATGATTTA 72 441 684 Antisense
TAGTGATCACTAAGAAGACCCCGCC 108 655 707 Antisense
ATCAACTCCATCGACTTACTTGAGA 411 27 732 Antisense
ATCGACTTACTTGAGATTTTGGAGC 4 23 741 Antisense
Sequence Source Affymetrix Proprietary Database