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[189734_at] protease inhibitor

Description K08B4.6 /REP_DB=WormBase Gene ID /WP=CE18035 /TR=Q9TYY2 /GB=AAC68983.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protease inhibitor
Cluster 6grp_highest_10_10 > 99      6grp_high1_10_10 > 99      4grp_highest_8_8 > 21      4grp_high_8_8 > 15      6grp_highest_nonorm > 78      6grp_total > 94      4grp_total > 0      6grp_cgc > 89      6grp_total_sub > Hat      6grp_rule_based > S5      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 599
1 2 3 4 range
A 728.8
(-3)
P 		768.2
(-2.4)
P 		887.6
(-0.7)
P 		1141.2
(3)
P 		412
B 681.6
(-2.2)
P 		609.7
(-3)
P 		768.2
(-1.3)
P 		1159.1
(3)
P 		549
C 672.3
(-1.7)
P 		560.4
(-3)
P 		946.5
(1.4)
P 		1087.5
(3)
P 		527
avr 694.2
(-2.4) 		646.1
(-3) 		867.4
(-0.3) 		1129.3
(3) 		483

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1352
1 2 3 4 5 6 range
A 1631.5
(-0.3)
P 		1192.2
(-3)
P 		1794.3
(0.7)
P 		1889
(1.3)
P 		2161.5
(3)
P 		1734.5
(0.4)
P 		969
B 1549.2
(-1.5)
P 		1566.4
(-1.5)
P 		1436.1
(-2.1)
P 		1231.9
(-3)
P 		2544.4
(3)
P 		2198.8
(1.4)
P 		1313
C 1594.5
(-1)
P 		1494.6
(-1.6)
P 		1246.2
(-3)
P 		1525.5
(-1.4)
P 		2306.1
(3)
P 		1727.2
(-0.3)
P 		1060
avr 1591.7
(-1.9) 		1417.7
(-3) 		1492.2
(-2.5) 		1548.8
(-2.1) 		2337.3
(3) 		1886.8
(0.1) 		920
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 179
1 2 3 4 range
A 265.3
(3)
P 		166.8
(-3)
P 		232
(1)
P 		167
(-3)
P 		99
B 217.4
(1.2)
P 		150.6
(-3)
P 		178
(-1.3)
P 		247
(3)
P 		96
C 222.6
(-0.8)
P 		161.1
(-3)
P 		329.9
(3)
P 		183.4
(-2.2)
P 		169
avr 235.1
(2.2) 		159.5
(-3) 		246.6
(3) 		199.1
(-0.3) 		87

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 733
1 2 3 4 5 6 range
A 300.8
(-3)
P 		424
(-0.9)
P 		390.8
(-1.5)
P 		479.1
(0)
P 		652.2
(3)
P 		422.3
(-0.9)
P 		351
B 539
(-1.2)
P 		521.4
(-1.3)
P 		348.7
(-2.8)
P 		326.3
(-3)
P 		1033.8
(3)
P 		819.9
(1.2)
P 		708
C 591
(0.9)
P 		456.1
(-1)
P 		317.2
(-2.9)
P 		306.8
(-3)
P 		746.2
(3)
P 		578.2
(0.7)
P 		439
avr 476.9
(-1.4) 		467.2
(-1.5) 		352.2
(-3) 		370.7
(-2.8) 		810.7
(3) 		606.8
(0.3) 		459
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189734_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10605
Sequence Type Exemplar sequence
Representative Public ID K08B4.6 NCBI
Target Description K08B4.6 /REP_DB=WormBase Gene ID /WP=CE18035 /TR=Q9TYY2 /GB=AAC68983.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protease inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068514(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068514 NCBI Caenorhabditis elegans Cystatin-LIke protease inhibitor family member (cli-2) (cli-2) mRNA, complete cds. 11/11 None
GENEFINDER00000004913 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:6090766:6093600:-1 11/11 None
K08B4.6 ENSEMBL cdna:known chromosome:CEL140:IV:6092613:6093631:-1 gene:K08B4.6 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000004907 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:6092664-6093606(-) 100.0 100.0
Public Domain and Genome References
Gene Title protease inhibitor
Gene Symbol cli-2
Ensembl K08B4.6
Entrez Gene 177372 Entrez gene
SwissProt Q9TYY2 EMBL-EBI
WormBase CE18035 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4869 cysteine protease inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC68983 Cystatin-like protease inhibitor protein 2 [Caenorhabditis elegans] emb|CAC33821.1| cystatin [Caenorhabditis elegans] ref|NP_500915.1| Cystatin-LIke protease inhibitor family member (cli-2) [Caenorhabditis elegans] 4.0E-68
blast AAC68983 Cystatin-like protease inhibitor protein 2 [Caenorhabditis elegans] emb|CAC33821.1| cystatin [Caenorhabditis elegans] ref|NP_500915.1| Cystatin-LIke protease inhibitor family member (cli-2) [Caenorhabditis elegans] 3.0E-63
blast CAE61605 Hypothetical protein CBG05524 [Caenorhabditis briggsae] 1.0E-42
blast CAE61605 Hypothetical protein CBG05524 [Caenorhabditis briggsae] 2.0E-40
blast AAC17767 Cystatin-like protease inhibitor protein 1, isoform a [Caenorhabditis elegans] emb|CAC33822.1| cystatin C [Caenorhabditis elegans] ref|NP_504565.1| Cystatin-LIke protease inhibitor family member (cli-1) [Caenorhabditis elegans] 4.0E-26
blast AAC17767 Cystatin-like protease inhibitor protein 1, isoform a [Caenorhabditis elegans] emb|CAC33822.1| cystatin C [Caenorhabditis elegans] ref|NP_504565.1| Cystatin-LIke protease inhibitor family member (cli-1) [Caenorhabditis elegans] 7.0E-25
Protein Domains
Database ID Description E-Value
Pfam IPR000010 EMBL-EBI Cysteine protease inhibitor 5.6E-18
Sequence
Target Sequence 
>C. ELEGANS:189734_AT
gcgtttcattcttcttatcgcacttgttttcgctgttcttgacggaataaattgccaaat
tgctggtggattgtctgatgtgaatgcctctgagtatactggagcagcttggaattcggt
gccggaaataaacagtaagaataatggacaaaactacatggttccaattaaggttgttaa
agctcaagttcaagttgttgccggaaccaatacagttttggaagttcttgttggagagtc
aact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCGTTTCATTCTTCTTATCGCACTT 535 291 15 Antisense
TCTTATCGCACTTGTTTTCGCTGTT 456 615 27 Antisense
GTTCTTGACGGAATAAATTGCCAAA 456 443 49 Antisense
GTGGATTGTCTGATGTGAATGCCTC 556 489 80 Antisense
GTCTGATGTGAATGCCTCTGAGTAT 419 471 87 Antisense
GCCTCTGAGTATACTGGAGCAGCTT 522 281 100 Antisense
GGAGCAGCTTGGAATTCGGTGCCGG 490 519 115 Antisense
GGACAAAACTACATGGTTCCAATTA 31 527 160 Antisense
AGCTCAAGTTCAAGTTGTTGCCGGA 271 79 195 Antisense
TTGCCGGAACCAATACAGTTTTGGA 652 695 212 Antisense
GGAAGTTCTTGTTGGAGAGTCAACT 154 531 234 Antisense
Sequence Source Affymetrix Proprietary Database