[Home] | [Total List]

[189685_at] Aldose reductase

Description C35D10.6 /REP_DB=WormBase Gene ID /WP=CE01200 /TR=Q18483 /GB=AAA62562.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Aldose reductase
Cluster 6grp_highest_10_10 > 57      6grp_high1_10_10 > 75      4grp_highest_8_8 > 15      4grp_high_8_8 > 14      6grp_highest_nonorm > 87      6grp_total > 65      4grp_total > 09      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 942
1 2 3 4 range
A 601.6
(-3)
P 		688.7
(-2.1)
P 		635.1
(-2.7)
P 		1183.8
(3)
P 		582
B 555.9
(-3)
P 		793.6
(-1.2)
P 		621.8
(-2.5)
P 		1365.5
(3)
P 		810
C 632.6
(-3)
P 		794.1
(-1.9)
P 		858.9
(-1.4)
P 		1498
(3)
P 		865
avr 596.7
(-3) 		758.8
(-1.7) 		705.3
(-2.1) 		1349.1
(3) 		752

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 839
1 2 3 4 5 6 range
A 798.5
(-3)
P 		1269.5
(3)
P 		1260.5
(2.9)
P 		1224
(2.4)
P 		889.7
(-1.8)
P 		1269.6
(3)
P 		471
B 635.5
(-3)
P 		1028.4
(0.5)
P 		1006.6
(0.3)
P 		1049
(0.7)
P 		982.5
(0.1)
P 		1309.6
(3)
P 		674
C 605.3
(-3)
P 		1116.6
(0.7)
P 		908.7
(-0.8)
P 		1285
(1.9)
P 		857.1
(-1.2)
P 		1443.8
(3)
P 		839
avr 679.8
(-3) 		1138.2
(1.2) 		1058.6
(0.4) 		1186
(1.6) 		909.8
(-0.9) 		1341
(3) 		661
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 155
1 2 3 4 range
A 219
(3)
P 		149.5
(-3)
P 		166
(-1.6)
P 		173.3
(-0.9)
P 		70
B 177.3
(-1.6)
P 		196
(-0.9)
P 		144.1
(-3)
P 		291
(3)
P 		147
C 209.4
(-3)
P 		228.3
(-1.7)
P 		299.3
(3)
P 		252.6
(-0.1)
P 		90
avr 201.9
(-1.7) 		191.3
(-3) 		203.1
(-1.5) 		239
(3) 		48

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 341
1 2 3 4 5 6 range
A 147.2
(-3)
P 		451.5
(3)
P 		274.5
(-0.5)
P 		310.4
(0.2)
P 		268.5
(-0.6)
P 		309.1
(0.2)
P 		304
B 221.1
(-3)
P 		342.3
(-0.3)
P 		244.4
(-2.5)
P 		277.9
(-1.7)
P 		399.2
(1)
P 		488.3
(3)
P 		267
C 224.4
(-3)
P 		340.7
(-0.3)
P 		231.3
(-2.8)
P 		258.4
(-2.2)
P 		277.3
(-1.8)
P 		483.3
(3)
P 		259
avr 197.6
(-3) 		378.2
(1.7) 		250.1
(-1.6) 		282.2
(-0.8) 		315
(0.1) 		426.9
(3) 		229
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189685_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6862
Sequence Type Exemplar sequence
Representative Public ID C35D10.6 NCBI
Target Description C35D10.6 /REP_DB=WormBase Gene ID /WP=CE01200 /TR=Q18483 /GB=AAA62562.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Aldose reductase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065610(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065610 NCBI Caenorhabditis elegans C35D10.6 (C35D10.6) mRNA, complete cds. 11/11 None
GENEFINDER00000029570 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4852286:4860647:1 11/11 None
SNAP00000029543 ENSEMBL cdna:SNAP chromosome:CEL140:III:4856164:4860647:1 11/11 None
C35D10.6 ENSEMBL cdna:known chromosome:CEL140:III:4859300:4860647:1 gene:C35D10.6 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4859304-4860647(+) 100.0 100.0
Public Domain and Genome References
Gene Title Aldose reductase
Ensembl C35D10.6
Entrez Gene 175645 Entrez gene
SwissProt Q18483 EMBL-EBI
WormBase CE01200 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast NP_001021203 CEll Death abnormality family member (ced-4) [Caenorhabditis elegans] gb|AAX22294.1| Cell death abnormality protein 4, isoform b [Caenorhabditis elegans] sp|P30429|CED4_CAEEL Cell death protein 0.0
blast NP_498009 C35D10.7a [Caenorhabditis elegans] gb|AAN63435.1| Hypothetical protein C35D10.7a [Caenorhabditis elegans] 0.0
blast CAA48781 ced-4 [Caenorhabditis elegans] ref|NP_001021202.1| CEll Death abnormality family member (ced-4) [Caenorhabditis elegans] gb|AAA62564.1| Cell death abnormality protein 4, isoform a [Caenorhabditis elegans] 0.0
blast NP_498010 C35D10.7b [Caenorhabditis elegans] gb|AAN63436.1| Hypothetical protein C35D10.7b [Caenorhabditis elegans] 0.0
blast S72568 hypothetical protein C35D10.7 - Caenorhabditis elegans 0.0
blast NP_498011 C35D10.6 [Caenorhabditis elegans] gb|AAA62562.1| Hypothetical protein C35D10.6 [Caenorhabditis elegans] 1.0E-165
blast CAE71107 Hypothetical protein CBG17960 [Caenorhabditis briggsae] 1.0E-132
Protein Domains
Database ID Description E-Value
Pfam IPR002182 EMBL-EBI NB-ARC domain 1.1E-38
Pfam IPR002182 EMBL-EBI NB-ARC domain 2.9E-87
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 1.1E-110
Pfam IPR001315 EMBL-EBI CARD interaction domain 8.6E-24
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 4.1E-102
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 1.1E-110
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000029570 6 552-574,587-609,614-636,787-809,1360-1379,1386-1408
Sequence
Target Sequence 
>C. ELEGANS:189685_AT
gccccatctaatgctggcgttaagaaagctcgggaaagcattgaggagtcactgagcaat
cttaaagtcgaatatttggatcttttgctcattcactggcctggaagttccctgaaaagc
gaaaatccggcaaacaagaaactgagagtggaaagttggaacgttatgtgtgaaatgatg
gctgaaggaaaattgcgttcagttggggtctctaattttgagatttgtcatttggaagaa
ttgaaaaaagattctaatgttgtcccagcagtcaatcaagttgagtatcatcctcatttc
catcaggacgatctggtcaaatactgtaacgaaaataacattcatttccaggcgtacagt
agccttggcagcccaacatatcgtaaacaattatccgaagaacctctgatcaaagaactt
gctcaaaagtacaatgtcgagattcctgtgctccttcttggatttgcttattgccaggga
attagcgtacttccgagaactacaaatccagagcatgttgctaccaattttaaagttact
aagctggcgattactcaagaagacatcgatcgtttattggctttgactgtcg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCCCCATCTAATGCTGGCGTTAAGA 627 283 247 Antisense
ATTTGGATCTTTTGCTCATTCACTG 509 17 320 Antisense
TTCACTGGCCTGGAAGTTCCCTGAA 459 685 338 Antisense
AATTGCGTTCAGTTGGGGTCTCTAA 429 177 437 Antisense
GATTCTAATGTTGTCCCAGCAGTCA 261 431 496 Antisense
GTATCATCCTCATTTCCATCAGGAC 690 453 531 Antisense
CAGGCGTACAGTAGCCTTGGCAGCC 214 209 595 Antisense
TTGGCAGCCCAACATATCGTAAACA 687 707 611 Antisense
CAATGTCGAGATTCCTGTGCTCCTT 414 183 678 Antisense
TGTGCTCCTTCTTGGATTTGCTTAT 373 557 693 Antisense
GATCGTTTATTGGCTTTGACTGTCG 586 417 814 Antisense
Sequence Source Affymetrix Proprietary Database