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[189672_at] carboxylesterase

Description C17H12.4 /REP_DB=WormBase Gene ID /WP=CE16865 /TR=O45083 /GB=AAC02583.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=carboxylesterase
Cluster 6grp_highest_10_10 > 49      6grp_high1_10_10 > 94      4grp_highest_8_8 > 54      4grp_high_8_8 > 09      6grp_highest_nonorm > 92      6grp_total > 84      4grp_total > 22      6grp_highest_sub > 04_05_06      6grp_high1_sub > In      6grp_total_sub > Hat      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 226
1 2 3 4 range
A 344.9
(3)
P 		300.2
(-0.1)
P 		259.1
(-3)
P 		277
(-1.7)
P 		86
B 337.2
(2.6)
P 		339
(2.7)
P 		233.2
(-3)
P 		344.5
(3)
P 		111
C 416.8
(1.3)
P 		309.7
(-3)
P 		427.7
(1.7)
P 		458.8
(3)
P 		149
avr 366.3
(3) 		316.3
(-2) 		306.7
(-3) 		360.1
(2.4) 		60

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 370
1 2 3 4 5 6 range
A 130
(-3)
P 		148.6
(-2.7)
P 		374.7
(1)
P 		499.6
(3)
P 		407.4
(1.5)
P 		300.7
(-0.2)
P 		370
B 147.1
(-3)
P 		168.5
(-2.6)
P 		224.6
(-1.7)
P 		352.5
(0.5)
P 		495.3
(3)
P 		495.2
(3)
P 		348
C 208.2
(-3)
P 		217.2
(-2.8)
P 		335.9
(-0.2)
P 		399.5
(1.1)
P 		365.3
(0.4)
P 		485
(3)
P 		277
avr 161.8
(-3) 		178.1
(-2.6) 		311.7
(0.4) 		417.2
(2.8) 		422.7
(2.9) 		427
(3) 		265
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 109
1 2 3 4 range
A 125.6
(3)
P 		65.2
(-1.3)
P 		67.7
(-1.1)
P 		40.5
(-3)
P 		85
B 107.5
(3)
P 		83.7
(0.3)
P 		54
(-3)
P 		73.4
(-0.8)
P 		54
C 138
(2.1)
P 		89.1
(-2)
P 		149.1
(3)
P 		77.4
(-3)
P 		72
avr 123.7
(3) 		79.3
(-1.4) 		90.3
(-0.3) 		63.8
(-3) 		60

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 177
1 2 3 4 5 6 range
A 24
(-3)
P 		52.8
(-1.3)
P 		81.6
(0.4)
P 		126.7
(3)
P 		122.9
(2.8)
P 		73.2
(-0.1)
P 		103
B 51.2
(-3)
P 		56.1
(-2.8)
P 		54.5
(-2.9)
P 		93.4
(-1.3)
P 		201.2
(3)
P 		184.7
(2.3)
P 		150
C 77.2
(-2.3)
P 		66.3
(-3)
P 		85.5
(-1.8)
P 		80.3
(-2.1)
P 		118.2
(0.2)
P 		162.4
(3)
P 		96
avr 50.8
(-3) 		58.4
(-2.5) 		73.9
(-1.6) 		100.1
(0.1) 		147.4
(3) 		140.1
(2.5) 		97
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189672_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9596
Sequence Type Exemplar sequence
Representative Public ID C17H12.4 NCBI
Target Description C17H12.4 /REP_DB=WormBase Gene ID /WP=CE16865 /TR=O45083 /GB=AAC02583.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=carboxylesterase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068642(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068642 NCBI Caenorhabditis elegans C17H12.4 (carboxylesterase) mRNA, complete cds. 11/11 None
SNAP00000015109 ENSEMBL cdna:SNAP chromosome:CEL140:IV:6798961:6802243:-1 9/11 None
GENEFINDER00000015131 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:6798961:6802243:-1 11/11 None
C17H12.4 ENSEMBL cdna:known chromosome:CEL140:IV:6798961:6802275:-1 gene:C17H12.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:6798966-6802249(-) 100.0 100.0
Public Domain and Genome References
Gene Title carboxylesterase
Ensembl C17H12.4
Entrez Gene 177445 Entrez gene
SwissProt O45083 EMBL-EBI
WormBase CE16865 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAC02583 Hypothetical protein C17H12.4 [Caenorhabditis elegans] ref|NP_501043.1| C17H12.4 [Caenorhabditis elegans] 0.0
blast CAE61475 Hypothetical protein CBG05369 [Caenorhabditis briggsae] 0.0
blast AAC47921 Hypothetical protein C01B10.10 [Caenorhabditis elegans] ref|NP_501021.2| C01B10.10 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 3.7E-109
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 6.4E-13
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501043.1 1 540-562
C17H12.4 1 540-562
SNAP00000015109 1 528-550
GENEFINDER00000015131 1 540-562
Sequence
Target Sequence 
>C. ELEGANS:189672_AT
gatgagactcaagccatcatggttcaagtaagagtaagagttaataatctactctcaaaa
aatgttccggcatatctttacgagtacacatatccaaaacatgcacgacatactgacgat
ttgttttatttaatgggtgttcatcgttttgaaaaggatgaaaatgaaattgaattggga
aaagtctacgaaacgatattcatgaattttgcaaaatttggtgacccgaaagaaggtttt
gagttggccaacgcagaaaatgaatcatattatgaagtatattgggatggagaaacagga
gaaagaccacaaatgaaaactaaatttgaagaaaagattatcaactattggctgaaagat
atggtggaatatgacaagcacatcacagaactcaaaaatcaaaaaatctcaataagaaag
ccagttgtcagattttatgaagaatcatctaaataccatcagtactcgtatatgacaatt
agcattttattgatttttaccatttttctaaccggctacttatttggaagatgttgttgt
gttggcaatcagga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATGAGACTCAAGCCATCATGGTTC 182 411 1171 Antisense
AATCTACTCTCAAAAAATGTTCCGG 184 169 1216 Antisense
TGTTCCGGCATATCTTTACGAGTAC 67 563 1233 Antisense
AACATGCACGACATACTGACGATTT 668 137 1268 Antisense
AGAAGGTTTTGAGTTGGCCAACGCA 148 67 1401 Antisense
GACAAGCACATCACAGAACTCAAAA 379 365 1543 Antisense
AGAAAGCCAGTTGTCAGATTTTATG 425 71 1585 Antisense
GAAGAATCATCTAAATACCATCAGT 220 341 1609 Antisense
TACCATCAGTACTCGTATATGACAA 269 649 1624 Antisense
TTCTAACCGGCTACTTATTTGGAAG 289 679 1676 Antisense
GATGTTGTTGTGTTGGCAATCAGGA 678 409 1700 Antisense
Sequence Source Affymetrix Proprietary Database