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[189667_at] cytochrome P450

Description C34B7.3 /REP_DB=WormBase Gene ID /WP=CE08567 /TR=SW:P90771 /GB=CAB05702.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cytochrome P450
Cluster 6grp_highest_10_10 > 31      6grp_high1_10_10 > 12      4grp_highest_8_8 > 63      4grp_high_8_8 > 28      6grp_highest_nonorm > 60      6grp_total > 23      4grp_total > 28      6grp_highest_sub > De      6grp_cgc > 31      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 190
1 2 3 4 range
A 340.5
(0.6)
P 		305.5
(-0.8)
P 		251.1
(-3)
P 		399.4
(3)
P 		148
B 210
(-3)
P 		399.8
(3)
P 		245.2
(-1.9)
P 		325.8
(0.7)
P 		190
C 350.5
(3)
P 		302.8
(0.4)
P 		241.6
(-3)
P 		337.9
(2.3)
P 		109
avr 300.3
(0) 		336
(2) 		246
(-3) 		354.4
(3) 		108

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 505
1 2 3 4 5 6 range
A 598.7
(3)
P 		581
(2.7)
P 		552.4
(2.3)
P 		422.8
(0.4)
P 		244.3
(-2.2)
P 		190.8
(-3)
P 		408
B 675.1
(3)
P 		572.6
(1.8)
P 		417.6
(-0.1)
P 		310.3
(-1.4)
P 		315.8
(-1.4)
P 		181.6
(-3)
P 		494
C 686.2
(3)
P 		547.2
(1.2)
P 		554.1
(1.3)
P 		372.5
(-1)
P 		335.8
(-1.5)
P 		216.2
(-3)
P 		470
avr 653.3
(3) 		566.9
(1.9) 		508
(1.1) 		368.5
(-0.7) 		298.6
(-1.7) 		196.2
(-3) 		457
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 67
1 2 3 4 range
A 124
(3)
P 		66.3
(-2.3)
P 		65.6
(-2.3)
P 		58.5
(-3)
P 		66
B 67
(-1.5)
P 		98.7
(3)
P 		56.8
(-3)
P 		69.4
(-1.2)
P 		42
C 116
(3)
P 		87.1
(0.1)
P 		84.2
(-0.2)
P 		57
(-3)
P 		59
avr 102.3
(3) 		84
(0.3) 		68.9
(-1.9) 		61.6
(-3) 		41

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 208
1 2 3 4 5 6 range
A 110.4
(-0.6)
P 		206.6
(3)
P 		120.3
(-0.2)
P 		107.2
(-0.7)
P 		73.7
(-2)
P 		46.4
(-3)
P 		160
B 234.9
(3)
P 		190.6
(1.4)
P 		101.4
(-1.8)
P 		82.2
(-2.5)
P 		128.3
(-0.8)
P 		67.7
(-3)
P 		167
C 254.3
(3)
P 		167
(0.1)
P 		141
(-0.7)
P 		74.9
(-2.9)
P 		108.7
(-1.8)
P 		72.4
(-3)
P 		182
avr 199.9
(3) 		188.1
(2.5) 		120.9
(-0.4) 		88.1
(-1.9) 		103.6
(-1.2) 		62.2
(-3) 		138
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189667_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.637
Sequence Type Exemplar sequence
Representative Public ID C34B7.3 NCBI
Target Description C34B7.3 /REP_DB=WormBase Gene ID /WP=CE08567 /TR=SW:P90771 /GB=CAB05702.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cytochrome P450
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059866(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059866 NCBI Caenorhabditis elegans CYtochrome P450 family member (cyp-36A1) (cyp-36A1) mRNA, complete cds. 11/11 None
SNAP00000044468 ENSEMBL cdna:SNAP chromosome:CEL140:I:8341912:8352103:-1 11/11 None
GENEFINDER00000044469 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:8350073:8354147:-1 11/11 None
C34B7.3 ENSEMBL cdna:known chromosome:CEL140:I:8349833:8354147:-1 gene:C34B7.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:8350003-8354077(-) 100.0 100.0
Public Domain and Genome References
Gene Title cytochrome P450
Gene Symbol cyp-36A1
Ensembl C34B7.3
Entrez Gene 183193 Entrez gene
SwissProt P90771 EMBL-EBI
WormBase CE08567 Wormbase
Functional Annotations
Ortholog
ID Title Organism
MU11KSUBB:MSA.36946.0_F_AT cytochrome P450, family 2, subfamily c, polypeptide 40 mm
MG-U74AV2:96334_F_AT cytochrome P450, family 2, subfamily c, polypeptide 40 mm
MG-U74AV2:96334_F_AT similar to Cyp2c40 protein mm
MOE430A:1423244_AT similar to Cyp2c40 protein mm
MOUSE430A_2:1423244_AT similar to Cyp2c40 protein mm
MOUSE430_2:1423244_AT similar to Cyp2c40 protein mm
MG-U74AV2:96334_F_AT hypothetical protein LOC545288 mm
MU19KSUBA:TC24183_AT PREDICTED: similar to Cyp2c40 protein [Mus musculus], mRNA sequence mm
MU19KSUBC:TC39135_F_AT PREDICTED: similar to Cyp2c40 protein [Mus musculus], mRNA sequence mm
MU19KSUBC:TC41208_F_AT PREDICTED: similar to Cyp2c40 protein [Mus musculus], mRNA sequence mm
RAT230_2:1370495_S_AT cytochrome P450 2c13 rn
RAE230A:1370495_S_AT cytochrome P450 2c13 rn
RT-U34:J02861MRNA_S_AT cytochrome P450 2c13 rn
RG-U34A:J02861MRNA_S_AT cytochrome P450 2c13 rn
RT-U34:M82855CDS_S_AT cytochrome P450 2c13 rn
RG-U34A:M82855CDS_S_AT cytochrome P450 2c13 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4497 monooxygenase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05702 Hypothetical protein C34B7.3 [Caenorhabditis elegans] ref|NP_492267.1| CYtochrome P450 family member (cyp-36A1) [Caenorhabditis elegans] sp|P90771|C36A1_CAEEL Probable cytochrome P450 CYP36A1 0.0
blast CAE60465 Hypothetical protein CBG04076 [Caenorhabditis briggsae] 0.0
blast AAB03125 Hypothetical protein C49C8.4 [Caenorhabditis elegans] ref|NP_501480.2| CYtochrome P450 family member (cyp-33E1) [Caenorhabditis elegans] 5.0E-69
Protein Families
Method ID Description E-Value
p450 CP1B_HUMAN Animalia; CYP1B1; hum; CP1B_HUMAN; Homo sapiens; Q16678 1.0E-106
p450 CP1B_HUMAN Animalia; CYP1B1; hum; CP1B_HUMAN; Homo sapiens; Q16678 1.0E-136
Protein Domains
Database ID Description E-Value
Pfam IPR001128 EMBL-EBI Cytochrome P450 3.0E-102
Pfam IPR001128 EMBL-EBI Cytochrome P450 3.4E-79
Pfam IPR001128 EMBL-EBI Cytochrome P450 3.0E-102
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_492267.1 1 2-21
C34B7.3 1 2-21
GENEFINDER00000044469 1 2-19
Sequence
Target Sequence 
>C. ELEGANS:189667_AT
tcattattgttcttcgattcgcattcttgtaccttgttaataatccagaaacacaaaaaa
gaattcatgaggaattggatagaaatgttggaagagaaaggcaagtagtaatggatgatc
agaagcatcttccatacacctgtgcctttcttcaagaagtatatcgcctcggatacgtac
ttccagtgaatttcctccgatgcacacttaccgatgttgaggattgtgaagggtatcgtt
tgaatgcgggaacacgtgtcattgcacaatttcaatcggttcatgttgacaagaaacact
tcccggatccagaacatttcaatccagatcgattcttgaatagtcgtggtgaatacatcc
gtgatgatcgtgtcaacccattctcaatgggaaaacgttcatgtcttggcgagaatcttg
ctcgtatggaagtattcctttatttctgtactttaatgcaaaacttcgaatggcatacag
atggcccatatgctccacc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCATTATTGTTCTTCGATTCGCATT 547 619 929 Antisense
GATTCGCATTCTTGTACCTTGTTAA 9 433 944 Antisense
CAGAAGCATCTTCCATACACCTGTG 262 205 1048 Antisense
TATATCGCCTCGGATACGTACTTCC 638 661 1088 Antisense
GTACTTCCAGTGAATTTCCTCCGAT 532 457 1105 Antisense
TCCGATGCACACTTACCGATGTTGA 42 595 1124 Antisense
GCGGGAACACGTGTCATTGCACAAT 500 291 1174 Antisense
TGACAAGAAACACTTCCCGGATCCA 197 571 1215 Antisense
TGATGATCGTGTCAACCCATTCTCA 391 567 1290 Antisense
GGGAAAACGTTCATGTCTTGGCGAG 566 493 1317 Antisense
ATACAGATGGCCCATATGCTCCACC 156 25 1403 Antisense
Sequence Source Affymetrix Proprietary Database