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[189666_s_at] aldose reductase

Description T08H10.1 /REP_DB=WormBase Gene ID /WP=CE17230 /TR=Q22352 /GB=AAA97992.2 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=aldose reductase
Cluster 6grp_highest_10_10 > 36      6grp_high1_10_10 > 40      4grp_highest_8_8 > 09      4grp_high_8_8 > 54      6grp_highest_nonorm > 38      6grp_total > 51      4grp_total > 58      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3959
1 2 3 4 range
A 5013
(-2.2)
P 		7654.2
(2.4)
P 		8016.6
(3)
P 		4563.5
(-3)
P 		3453
B 6067.8
(0.2)
P 		6681.6
(1.2)
P 		7821.9
(3)
P 		4073.6
(-3)
P 		3748
C 4903.6
(-0.8)
P 		6384
(3)
P 		6370.1
(3)
P 		4058
(-3)
P 		2326
avr 5328.1
(-0.9) 		6906.6
(2.1) 		7402.9
(3) 		4231.7
(-3) 		3171

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 4794
1 2 3 4 5 6 range
A 7123.8
(2.3)
P 		6309.4
(-0.8)
P 		6516.9
(-0)
P 		7308.6
(3)
P 		5746
(-3)
P 		6813.9
(1.1)
P 		1563
B 5783.6
(-1.1)
P 		5708.4
(-1.2)
P 		7723.3
(3)
P 		7007.3
(1.5)
P 		4850.5
(-3)
P 		5408.9
(-1.8)
P 		2873
C 5891.5
(-2)
P 		5595.7
(-2.4)
P 		9644.8
(3)
P 		6966.8
(-0.6)
P 		5145
(-3)
P 		6008.7
(-1.8)
P 		4500
avr 6266.3
(-0.7) 		5871.2
(-1.6) 		7961.7
(3) 		7094.2
(1.1) 		5247.2
(-3) 		6077.2
(-1.2) 		2715
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1552
1 2 3 4 range
A 1825.2
(1.9)
P 		1661.5
(1.2)
P 		2095.7
(3)
P 		668
(-3)
P 		1428
B 1935
(3)
P 		1650.2
(1.4)
P 		1812.5
(2.3)
P 		868.1
(-3)
P 		1067
C 1623.2
(0.7)
P 		1835.4
(1.5)
P 		2220.2
(3)
P 		684.2
(-3)
P 		1536
avr 1794.5
(1.9) 		1715.7
(1.5) 		2042.8
(3) 		740.1
(-3) 		1303

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1142
1 2 3 4 5 6 range
A 1313.2
(-3)
P 		2243.9
(3)
P 		1419.2
(-2.3)
P 		1853.6
(0.5)
P 		1733.9
(-0.3)
P 		1659
(-0.8)
P 		931
B 2012.4
(2.8)
P 		1900.1
(-1.4)
P 		1875.4
(-2.3)
P 		1856
(-3)
P 		1970.7
(1.3)
P 		2016.9
(3)
P 		161
C 2183.7
(1.5)
P 		1707.4
(-1.3)
P 		2454.8
(3)
P 		1401
(-3)
P 		1664.8
(-1.5)
P 		2011.4
(0.5)
P 		1054
avr 1836.4
(0.2) 		1950.5
(3) 		1916.5
(2.2) 		1703.5
(-3) 		1789.8
(-0.9) 		1895.8
(1.7) 		247
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189666_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15723
Sequence Type Exemplar sequence
Representative Public ID T08H10.1 NCBI
Target Description T08H10.1 /REP_DB=WormBase Gene ID /WP=CE17230 /TR=Q22352 /GB=AAA97992.2 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=aldose reductase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071830(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071830 NCBI Caenorhabditis elegans T08H10.1 (T08H10.1) mRNA, complete cds. 11/11 None
SNAP00000001969 ENSEMBL cdna:SNAP chromosome:CEL140:V:4483319:4486231:1 11/11 None
GENEFINDER00000001973 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:4483319:4486210:1 11/11 None
T08H10.1 ENSEMBL cdna:known chromosome:CEL140:V:4483319:4486281:1 gene:T08H10.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:4483318-4486231(+) 100.0 100.0
Public Domain and Genome References
Gene Title aldose reductase
Ensembl T08H10.1
Entrez Gene 178844 Entrez gene
SwissProt Q22352 EMBL-EBI
WormBase CE17230 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1628404_AT dm
DROSGENOME1:154286_AT dm
Protein Similarities
Method ID Description E-Value
blast AAA97992 Hypothetical protein T08H10.1 [Caenorhabditis elegans] ref|NP_504231.1| T08H10.1 [Caenorhabditis elegans] 0.0
blast CAE56773 Hypothetical protein CBG24579 [Caenorhabditis briggsae] 1.0E-157
blast CAE56773 Hypothetical protein CBG24579 [Caenorhabditis briggsae] 1.0E-151
blast CAE73313 Hypothetical protein CBG20740 [Caenorhabditis briggsae] 8.0E-66
Protein Domains
Database ID Description E-Value
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 3.5E-118
Sequence
Target Sequence 
>C. ELEGANS:189666_S_AT
ccaacttcagttgcaaccagcttcaagcgctctatgacgccgccgaagtgaagccagcca
accaacaagtcgagtgtcacatctattggccacaacaagagctccgtgctctgtgcaaaa
aactcggagtcactgttacagcatacgcaccacttggctcaccaggcagaaaagctgctc
gtccggacggtgtctggccggaaggtgacccacttctcgagccaatcgtcaaacaactgg
ctgccaagtatcacaaaactgctgcacagattctcattcgccacctgactcaacacggta
tttcgacgattccgaagagtgtcagtccggacagaattgttgagaatatctcgacgtttg
attttaagctgagcgatgaggatatgcacactttgaacagtatcgagaccagaactagac
ttttcatcgctgatttcgctgtcaagcatccattcttcccacacgacgacattgaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCAACTTCAGTTGCAACCAGCTTCA 399 275 500 Antisense
CCAGCTTCAAGCGCTCTATGACGCC 481 273 516 Antisense
CTATGACGCCGCCGAAGTGAAGCCA 70 183 531 Antisense
GAGTGTCACATCTATTGGCCACAAC 530 401 571 Antisense
CACTGTTACAGCATACGCACCACTT 596 195 630 Antisense
ACCACTTGGCTCACCAGGCAGAAAA 368 83 648 Antisense
GGACGGTGTCTGGCCGGAAGGTGAC 691 523 684 Antisense
CCACTTCTCGAGCCAATCGTCAAAC 351 273 709 Antisense
AACTGCTGCACAGATTCTCATTCGC 631 141 756 Antisense
GCCACCTGACTCAACACGGTATTTC 30 279 779 Antisense
TTCTTCCCACACGACGACATTGACA 520 689 952 Antisense
Sequence Source Affymetrix Proprietary Database