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[189627_at] carboxypeptidase

Description Y59C2A.1 /REP_DB=WormBase Gene ID /WP=CE20329 /TR=Q9TZC6 /GB=AAC68743.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=carboxypeptidase
Cluster 6grp_highest_10_10 > 90      6grp_high1_10_10 > 19      4grp_highest_8_8 > 15      4grp_high_8_8 > 13      6grp_highest_nonorm > 71      6grp_total > 19      4grp_total > 10      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 746
1 2 3 4 range
A 430.7
(-0.2)
P 		530.6
(1.4)
P 		248
(-3)
P 		637.3
(3)
P 		389
B 332.3
(-2.6)
P 		288.7
(-3)
P 		417.6
(-1.9)
P 		994.4
(3)
P 		706
C 380.1
(-2.9)
P 		449.7
(-2)
P 		373.5
(-3)
P 		828
(3)
P 		455
avr 381
(-2.6) 		423
(-2) 		346.4
(-3) 		819.9
(3) 		474

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 238
1 2 3 4 5 6 range
A 376.7
(3)
P 		361.2
(2.4)
P 		292.3
(-0.4)
P 		356.2
(2.2)
P 		350.3
(1.9)
P 		228.6
(-3)
P 		148
B 466.1
(3)
P 		333.2
(-0.7)
P 		297.4
(-1.8)
P 		253.3
(-3)
P 		405.6
(1.3)
P 		262.8
(-2.7)
P 		213
C 345.1
(2.3)
P 		358.9
(3)
P 		243.3
(-3)
P 		291.5
(-0.5)
P 		334
(1.7)
P 		263.3
(-2)
P 		116
avr 396
(3) 		351.1
(1.1) 		277.7
(-1.9) 		300.3
(-1) 		363.3
(1.6) 		251.6
(-3) 		144
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 147
1 2 3 4 range
A 156.8
(3)
P 		115.2
(0.3)
P 		64.8
(-3)
P 		93.3
(-1.1)
P 		92
B 106
(-1.5)
P 		71.3
(-3)
P 		96.8
(-1.9)
P 		211.9
(3)
P 		141
C 125.8
(-3)
P 		129.3
(-1.5)
P 		130.2
(-1.1)
P 		139.6
(3)
P 		14
avr 129.5
(0.8) 		105.3
(-2.1) 		97.3
(-3) 		148.3
(3) 		51

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 109
1 2 3 4 5 6 range
A 69.4
(-1.9)
P 		128.4
(3)
P 		63.6
(-2.3)
P 		90.4
(-0.1)
P 		105.7
(1.1)
P 		55.6
(-3)
P 		73
B 162.2
(2.8)
P 		110.9
(-0.3)
P 		72.2
(-2.7)
P 		67.1
(-3)
P 		164.8
(3)
P 		98
(-1.1)
P 		98
C 127.9
(3)
P 		109.5
(1.4)
P 		61.9
(-2.7)
P 		58.6
(-3)
P 		108.1
(1.3)
P 		88.2
(-0.4)
P 		69
avr 119.8
(2.4) 		116.3
(2) 		65.9
(-3) 		72
(-2.4) 		126.2
(3) 		80.6
(-1.5) 		60
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189627_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5232
Sequence Type Exemplar sequence
Representative Public ID Y59C2A.1 NCBI
Target Description Y59C2A.1 /REP_DB=WormBase Gene ID /WP=CE20329 /TR=Q9TZC6 /GB=AAC68743.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=carboxypeptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061812(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061812 NCBI Caenorhabditis elegans Y59C2A.1 (carboxypeptidase) mRNA, complete cds. 11/11 None
GENEFINDER00000003204 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:2208119:2212726:1 11/11 None
Y59C2A.1 ENSEMBL cdna:known chromosome:CEL140:II:2208113:2212864:1 gene:Y59C2A.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:2208117-2212891(+) 100.0 100.0
Public Domain and Genome References
Gene Title carboxypeptidase
Ensembl Y59C2A.1
Entrez Gene 173577 Entrez gene
SwissProt Q9TZC6 EMBL-EBI
WormBase CE31658 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1630302_AT dm
DROSGENOME1:148332_AT dm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
4182 carboxypeptidase A activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC68743 Hypothetical protein Y59C2A.1 [Caenorhabditis elegans] ref|NP_494213.2| Y59C2A.1 [Caenorhabditis elegans] 0.0
blast CAE73874 Hypothetical protein CBG21465 [Caenorhabditis briggsae] 0.0
blast BAD60916.1 molting fluid carboxypeptidase A [Bombyx mori] 8.0E-63
blast XP_786036 PREDICTED: similar to Carboxypeptidase A2 precursor [Strongylocentrotus purpuratus] 5.0E-55
Protein Domains
Database ID Description E-Value
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 2.5E-62
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 2.7E-71
Sequence
Target Sequence 
>C. ELEGANS:189627_AT
aaacccggagcaagaacgtcacagtgaaccgttggtgcgttggagccgacgccaaccgta
actgggggtaccgatggggtgaagccggtgcaaatcgtacaccttgctcgaatatctata
tgggaagccatccgtattcggagccggagattcgagggctcaaagagtttttcacttggc
aaatcactaatccaatggtctacatcagtcttcattcctatgggcaactacttctatcgc
catggggttacactaacgagagaactgaaaattatcaggatcagcaaaacgccgctaagg
aggccgctcaagccatcaaaaac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAACCCGGAGCAAGAACGTCACAGT 147 127 761 Antisense
ACGTCACAGTGAACCGTTGGTGCGT 412 95 776 Antisense
TTGGTGCGTTGGAGCCGACGCCAAC 615 649 792 Antisense
GGGGTGAAGCCGGTGCAAATCGTAC 256 385 836 Antisense
AATCGTACACCTTGCTCGAATATCT 478 169 853 Antisense
TATGGGAAGCCATCCGTATTCGGAG 649 651 879 Antisense
ATGGTCTACATCAGTCTTCATTCCT 423 51 955 Antisense
TCATTCCTATGGGCAACTACTTCTA 196 619 972 Antisense
ACTACTTCTATCGCCATGGGGTTAC 571 99 987 Antisense
CAAAACGCCGCTAAGGAGGCCGCTC 319 191 1045 Antisense
GGAGGCCGCTCAAGCCATCAAAAAC 513 513 1059 Antisense
Sequence Source Affymetrix Proprietary Database